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BRPI0713182A8 - usos de adapaleno ou de um de seus sais farmaceuticamente aceitáveis, kit e produto - Google Patents

usos de adapaleno ou de um de seus sais farmaceuticamente aceitáveis, kit e produto

Info

Publication number
BRPI0713182A8
BRPI0713182A8 BRPI0713182A BRPI0713182A BRPI0713182A8 BR PI0713182 A8 BRPI0713182 A8 BR PI0713182A8 BR PI0713182 A BRPI0713182 A BR PI0713182A BR PI0713182 A BRPI0713182 A BR PI0713182A BR PI0713182 A8 BRPI0713182 A8 BR PI0713182A8
Authority
BR
Brazil
Prior art keywords
adapalene
pharmaceutically acceptable
acceptable salts
kit
product
Prior art date
Application number
BRPI0713182A
Other languages
English (en)
Inventor
Loesche Christian
Gross Denis
Abou-Chacra Vernet Marie-Line
Poncet Michel
Original Assignee
Galderma Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37763873&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0713182(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Galderma Res & Dev filed Critical Galderma Res & Dev
Publication of BRPI0713182A2 publication Critical patent/BRPI0713182A2/pt
Publication of BRPI0713182A8 publication Critical patent/BRPI0713182A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

usos de adapaleno ou de um de seus sais farmaceuticamente aceitáveis, kit e produto. a presente invenção trata do uso de adapaleno ou de um de seus sais farmaceuticamente aceitáveis para a fabricação de uma composição farmacêutica a fim de reduzir o número de lesões acnéicas, por meio de uma aplicação tópica diária, em combinação ou associação com peróxido de benzoila (bpo). o tratamento recomendado pode assumir a forma de uma composição farmacêutica que combina adapaleno e bpo ou a aplicação concomitante de duas composições farmacêuticas, uma das quais compreende o adapaleno e a outra, hpo.
BRPI0713182A 2006-07-13 2007-07-12 usos de adapaleno ou de um de seus sais farmaceuticamente aceitáveis, kit e produto BRPI0713182A8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR0652968 2006-07-13
FR0652968A FR2903603B1 (fr) 2006-07-13 2006-07-13 Combinaison d'adapalene et de peroxyde de benzole dans le traitement de l'acne
US83349106P 2006-07-27 2006-07-27
US60/833,491 2006-07-27
PCT/EP2007/057207 WO2008006888A1 (en) 2006-07-13 2007-07-12 Combination of adapalene and benzoyl peroxide for treating acne lesions

Publications (2)

Publication Number Publication Date
BRPI0713182A2 BRPI0713182A2 (pt) 2012-04-17
BRPI0713182A8 true BRPI0713182A8 (pt) 2018-01-02

Family

ID=37763873

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0713182A BRPI0713182A8 (pt) 2006-07-13 2007-07-12 usos de adapaleno ou de um de seus sais farmaceuticamente aceitáveis, kit e produto

Country Status (23)

Country Link
US (6) US8129362B2 (pt)
EP (2) EP2450035B1 (pt)
JP (3) JP2009542779A (pt)
KR (3) KR20150003917A (pt)
CN (1) CN101541320B (pt)
AR (1) AR061989A1 (pt)
AU (1) AU2007274288B2 (pt)
BR (1) BRPI0713182A8 (pt)
CA (1) CA2656456A1 (pt)
CO (1) CO6150136A2 (pt)
CY (1) CY1121398T1 (pt)
DK (2) DK2450035T3 (pt)
ES (2) ES2423951T3 (pt)
FR (1) FR2903603B1 (pt)
HU (1) HUE043502T2 (pt)
LT (1) LT2450035T (pt)
MX (1) MX2009000319A (pt)
PL (2) PL2046318T3 (pt)
PT (2) PT2450035T (pt)
RU (3) RU2009104949A (pt)
SI (2) SI2450035T1 (pt)
TR (1) TR201819658T4 (pt)
WO (1) WO2008006888A1 (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7820186B2 (en) 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
FR2910321B1 (fr) 2006-12-21 2009-07-10 Galderma Res & Dev S N C Snc Gel creme comprenant au moins un retinoide et du peroxyde de benzole
FR2910320B1 (fr) 2006-12-21 2009-02-13 Galderma Res & Dev S N C Snc Emulsion comprenant au moins un retinoide et du peroxyde de benzole
ES2546029T3 (es) * 2007-01-30 2015-09-17 Galderma Research & Development Uso de adapaleno y peróxido de benzoilo para el tratamiento a largo plazo del acné vulgar
KR101538187B1 (ko) * 2007-11-30 2015-07-22 갈데르마 리써어치 앤드 디벨로프먼트 하나 이상의 나프토산 유도체, 과산화 벤조일 및 하나 이상의 필름-형성제를 함유하는 조성물
JP2011520849A (ja) * 2008-05-16 2011-07-21 ガルデルマ・リサーチ・アンド・デヴェロップメント ざ瘡関連疾患を処置するための治療投与法
KR20120118064A (ko) * 2010-02-09 2012-10-25 갈데르마 리써어치 앤드 디벨로프먼트 염증후 과다색소침착의 감소로 비코카서스인 모집단에서의 여드름 치료를 위한 아다팔렌과 벤조일 퍼옥사이드의 조합물을 포함하는 피부용 조성물
WO2011135090A1 (en) * 2010-04-29 2011-11-03 Galderma Research & Development Method for treating scars with adapalene 0.3%
FR2969491B1 (fr) * 2010-12-23 2013-07-12 Galderma Res & Dev Mousses dermatologiques obtenues a partir d'un gel ou d'une suspension contenant une combinaison d'adapalene et de bpo
US8563535B2 (en) * 2011-03-29 2013-10-22 Kamal Mehta Combination composition comprising benzoyl peroxide and adapalene
CA2870690A1 (en) * 2012-05-25 2013-11-28 Galderma Research & Development Treatment of preadolescent moderate acne vulgaris
BR112015011673B1 (pt) 2012-11-20 2021-03-09 Allergan, Inc. composição e uso da mesma
AU2015239688B2 (en) * 2014-04-01 2020-06-25 Galderma Research & Development Combination of adapalene and benzoyl peroxide for treating acne scars
SG11201700449RA (en) 2014-07-25 2017-02-27 Galderma Res & Dev Combination of adapalene and benzoyl peroxide for the treatment of severe acne
WO2017029665A1 (en) * 2015-08-20 2017-02-23 Sol-Gel Technologies Ltd. Compositions for topical application comprising benzoyl peroxide and adapalene
JP6679299B2 (ja) * 2015-12-21 2020-04-15 第一三共ヘルスケア株式会社 ニキビ治療用外用医薬組成物
WO2018080284A1 (ko) * 2016-10-31 2018-05-03 (주)동구바이오제약 여드름 치료용 약물의 생체이용률을 증진시키는 약학적 조성물
KR101986177B1 (ko) * 2016-10-31 2019-06-05 (주)동구바이오제약 여드름 치료용 약물의 생체이용률을 증진시키는 약학적 조성물
MX395001B (es) * 2017-03-08 2025-03-24 Centro Int De Cosmiatria S A P I De C V Composición y método para el tratamiento tópico del acné severo.
RU2019134342A (ru) * 2017-03-30 2021-04-28 Сайнтелл, Ллк Способ лечения и предупреждения инфекций
WO2021019092A1 (en) 2019-08-01 2021-02-04 Bausch Health Ireland Limited Topical compositions
WO2023177625A1 (en) * 2022-03-14 2023-09-21 Blue Hill Technologies Llc Shelf-stable formulations of benzoyl peroxide and methods of producing same

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW203552B (en) * 1992-02-18 1993-04-11 J Baroody Lloyd Compositions of clindamycin and benzoyl peroxide for acne treatment
FR2727609B1 (fr) 1994-12-06 1997-01-10 Oreal Ensemble de distribution pour l'application d'un produit de consistance liquide a pateuse
FR2775566B1 (fr) 1998-03-03 2000-05-12 Oreal Cupule porte raisin et ensemble de conditionnement pour un produit de maquillage la comportant
US6559189B2 (en) * 1999-04-28 2003-05-06 Regents Of The University Of Michigan Non-toxic antimicrobial compositions and methods of use
FR2806273B1 (fr) 2000-03-16 2002-10-04 Oreal Dispositif de conditionnement et d'application d'un produit cosmetique ou de soin
US7820186B2 (en) * 2001-12-21 2010-10-26 Galderma Research & Development Gel composition for once-daily treatment of common acne comprising a combination of benzoyl peroxide and adapalene and/or adapalene salt
FR2833841B1 (fr) * 2001-12-21 2005-07-22 Galderma Res & Dev Gel comprenant au moins un retinoide et du peroxyde de benzoyle
FR2837101B1 (fr) 2002-03-12 2004-07-02 Galderma Res & Dev Utilisation de l'acide 6-[1-adamantyl)-4-methoxyphenyl]-2- naphthoique pour le traitement de desordres dermatologiques
GB0301577D0 (en) * 2003-01-23 2003-02-26 Edko Pazarlama Tanitim Ltd Sti Topical pharmaceutical and/or cosmetic dispense systems
WO2005009458A1 (en) * 2003-07-23 2005-02-03 Xoma Technology Ltd. Use of xmp-629 for the treatment of acne
US20050239723A1 (en) * 2004-04-27 2005-10-27 Amin Avinash N Compositions and methods useful for treatment of acne
US20060128808A1 (en) * 2004-10-20 2006-06-15 Galderma Research & Development, S.N.C. Method of using adapalene in acne maintenance therapy
AR054805A1 (es) * 2005-06-29 2007-07-18 Stiefel Laboratories Composiciones topicas para el tratamiento de la piel
FR2901139B1 (fr) 2006-05-17 2009-03-20 Galderma Res & Dev S N C Snc Compositions comprenant au moins un derive de l'acide naphtoique et du peroxyde de benzoyle, leurs procedes de preparation, et leurs utilisations

Also Published As

Publication number Publication date
ES2423951T3 (es) 2013-09-25
CY1121398T1 (el) 2020-05-29
KR20160120352A (ko) 2016-10-17
US20120115947A1 (en) 2012-05-10
RU2009104949A (ru) 2010-08-20
DK2450035T3 (en) 2019-02-25
EP2450035A1 (en) 2012-05-09
CN101541320B (zh) 2014-04-09
PT2450035T (pt) 2019-02-26
SI2046318T1 (sl) 2013-11-29
BRPI0713182A2 (pt) 2012-04-17
FR2903603B1 (fr) 2009-03-20
CO6150136A2 (es) 2010-04-20
US20120059063A1 (en) 2012-03-08
US8071644B2 (en) 2011-12-06
EP2046318B1 (en) 2013-06-05
RU2012144414A (ru) 2014-04-27
PL2046318T3 (pl) 2013-12-31
DK2046318T3 (da) 2013-08-05
AR061989A1 (es) 2008-08-10
PT2046318E (pt) 2013-09-04
KR20150003917A (ko) 2015-01-09
MX2009000319A (es) 2009-03-12
AU2007274288B2 (en) 2013-05-02
SI2450035T1 (sl) 2019-03-29
WO2008006888A1 (en) 2008-01-17
US8785420B2 (en) 2014-07-22
EP2046318A1 (en) 2009-04-15
CA2656456A1 (en) 2008-01-17
TR201819658T4 (tr) 2019-01-21
JP2009542779A (ja) 2009-12-03
JP2014040481A (ja) 2014-03-06
RU2012136952A (ru) 2014-03-10
JP2016029094A (ja) 2016-03-03
US20090253788A1 (en) 2009-10-08
US8129362B2 (en) 2012-03-06
CN101541320A (zh) 2009-09-23
US20140296340A1 (en) 2014-10-02
PL2450035T3 (pl) 2019-04-30
HUE043502T2 (hu) 2019-08-28
FR2903603A1 (fr) 2008-01-18
AU2007274288A1 (en) 2008-01-17
US20170202803A1 (en) 2017-07-20
LT2450035T (lt) 2019-01-25
US20080033047A1 (en) 2008-02-07
ES2703505T3 (es) 2019-03-11
EP2450035B1 (en) 2018-11-21
KR20090028764A (ko) 2009-03-19

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]