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BRPI0711328A2 - atuação de arranjos microfluìdicos paralelos - Google Patents

atuação de arranjos microfluìdicos paralelos Download PDF

Info

Publication number
BRPI0711328A2
BRPI0711328A2 BRPI0711328-5A BRPI0711328A BRPI0711328A2 BR PI0711328 A2 BRPI0711328 A2 BR PI0711328A2 BR PI0711328 A BRPI0711328 A BR PI0711328A BR PI0711328 A2 BRPI0711328 A2 BR PI0711328A2
Authority
BR
Brazil
Prior art keywords
actuator
rating
external
block
performance
Prior art date
Application number
BRPI0711328-5A
Other languages
English (en)
Inventor
Andrew Johnson
John R Gilbert
Manish Deshpande
Hugh Lewis
Bernard Bunenr
Original Assignee
Cytonome Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytonome Inc filed Critical Cytonome Inc
Publication of BRPI0711328A2 publication Critical patent/BRPI0711328A2/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B07—SEPARATING SOLIDS FROM SOLIDS; SORTING
    • B07C—POSTAL SORTING; SORTING INDIVIDUAL ARTICLES, OR BULK MATERIAL FIT TO BE SORTED PIECE-MEAL, e.g. BY PICKING
    • B07C5/00—Sorting according to a characteristic or feature of the articles or material being sorted, e.g. by control effected by devices which detect or measure such characteristic or feature; Sorting by manually actuated devices, e.g. switches
    • B07C5/34—Sorting according to other particular properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0439—Moving fluids with specific forces or mechanical means specific forces vibrational forces ultrasonic vibrations, vibrating piezo elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Fluid Mechanics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Sustainable Development (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

ATUAçãO DE ARRANJOS MICROFLUìDICOS PARALELOS. é descrito um atuador melhorado para uso em um sistema de classificação de partículas microfluídicas que utiliza um esquema de empacotamento defasado para uma pluralidade de atuadores usada para desviar seletivamente uma partícula em um canal de classificação associado de uma corrente de canais. Um bloco do atuador pode ser provido para alojar um arranjo bidimensional de atuadores, cada qual configurado para se alinhar com um orifício de atuação em um chip de classificação associado contendo uma pluralidade de canais de classificação. O bloco do atuador pode incluir um dispositivo de tensionamento incorporado para pré-tensionar cada atuador alojado pelo bloco. Um atuador compreendendo uma pilha piezoelétrica pode empregar conexão elétrica a base de contato, em vez de arames solados, para melhorar a densidade de empacotamento. O atuador pode ser um atuador externo. Ou seja, o atuador externo é externo ao substrato no qual os canais de classificação são formados.
BRPI0711328-5A 2006-05-05 2007-05-04 atuação de arranjos microfluìdicos paralelos BRPI0711328A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79815406P 2006-05-05 2006-05-05
PCT/US2007/010959 WO2007130647A2 (en) 2006-05-05 2007-05-04 Actuation of parallel microfluidic arrays

Publications (1)

Publication Number Publication Date
BRPI0711328A2 true BRPI0711328A2 (pt) 2011-08-30

Family

ID=38668370

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0711328-5A BRPI0711328A2 (pt) 2006-05-05 2007-05-04 atuação de arranjos microfluìdicos paralelos

Country Status (10)

Country Link
US (2) US8123044B2 (pt)
EP (1) EP2026912B1 (pt)
JP (1) JP5059851B2 (pt)
KR (1) KR20090024691A (pt)
CN (1) CN101460260A (pt)
AU (1) AU2007248494B2 (pt)
BR (1) BRPI0711328A2 (pt)
CA (1) CA2651250C (pt)
IL (1) IL195116A (pt)
WO (1) WO2007130647A2 (pt)

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US20070065808A1 (en) * 2002-04-17 2007-03-22 Cytonome, Inc. Method and apparatus for sorting particles
US9943847B2 (en) 2002-04-17 2018-04-17 Cytonome/St, Llc Microfluidic system including a bubble valve for regulating fluid flow through a microchannel
US11243494B2 (en) 2002-07-31 2022-02-08 Abs Global, Inc. Multiple laminar flow-based particle and cellular separation with laser steering
ZA200603614B (en) 2003-10-30 2007-09-26 Cytonome Inc Multilayer hydrodynamic sheath flow structure
US9260693B2 (en) 2004-12-03 2016-02-16 Cytonome/St, Llc Actuation of parallel microfluidic arrays
US20120292367A1 (en) 2006-01-31 2012-11-22 Ethicon Endo-Surgery, Inc. Robotically-controlled end effector
US8360244B2 (en) * 2008-06-09 2013-01-29 Wyatt Technology Corporation Method and apparatus for optimizing the separation of small particles using the asymmetric flow field flow fractionation method
US9645010B2 (en) 2009-03-10 2017-05-09 The Regents Of The University Of California Fluidic flow cytometry devices and methods
US9134221B2 (en) 2009-03-10 2015-09-15 The Regents Of The University Of California Fluidic flow cytometry devices and particle sensing based on signal-encoding
CN102472697A (zh) * 2009-07-06 2012-05-23 索尼公司 微流体装置
US9963739B2 (en) 2010-05-21 2018-05-08 Hewlett-Packard Development Company, L.P. Polymerase chain reaction systems
US9395050B2 (en) 2010-05-21 2016-07-19 Hewlett-Packard Development Company, L.P. Microfluidic systems and networks
US10132303B2 (en) 2010-05-21 2018-11-20 Hewlett-Packard Development Company, L.P. Generating fluid flow in a fluidic network
WO2011146069A1 (en) 2010-05-21 2011-11-24 Hewlett-Packard Development Company, L.P. Fluid ejection device including recirculation system
KR101885936B1 (ko) 2010-10-21 2018-09-10 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 무선 전력이 공급되는 전자 회로를 포함하는 미세 유체
US10908066B2 (en) 2010-11-16 2021-02-02 1087 Systems, Inc. Use of vibrational spectroscopy for microfluidic liquid measurement
US8695618B2 (en) 2010-12-22 2014-04-15 Carnegie Mellon University 3D chemical pattern control in 2D fluidics devices
US8871500B2 (en) 2011-01-21 2014-10-28 Innovative Micro Technology MEMS particle sorting actuator and method of manufacturing
WO2014062719A2 (en) 2012-10-15 2014-04-24 Nanocellect Biomedical, Inc. Systems, apparatus, and methods for sorting particles
US9757726B2 (en) 2013-03-14 2017-09-12 Inguran, Llc System for high throughput sperm sorting
US10190960B2 (en) 2013-03-14 2019-01-29 Cytonome/St, Llc Micro-lens systems for particle processing systems
EP4220124A1 (en) 2013-03-14 2023-08-02 Cytonome/ST, LLC Hydrodynamic focusing apparatus and methods
EP2972207B1 (en) 2013-03-14 2022-09-21 Cytonome/ST, LLC Assemblies and methods for reducing optical crosstalk in particle processing systems
US10662408B2 (en) 2013-03-14 2020-05-26 Inguran, Llc Methods for high throughput sperm sorting
US10371622B2 (en) 2013-03-14 2019-08-06 Inguran, Llc Device for high throughput sperm sorting
EP4332546A3 (en) 2013-03-14 2024-06-05 Cytonome/ST, LLC Operatorless particle processing systems and methods
EP3569313A1 (en) * 2013-03-15 2019-11-20 GPB Scientific, LLC On-chip microfluidic processing of particles
US8961904B2 (en) 2013-07-16 2015-02-24 Premium Genetics (Uk) Ltd. Microfluidic chip
US11796449B2 (en) 2013-10-30 2023-10-24 Abs Global, Inc. Microfluidic system and method with focused energy apparatus
US10960396B2 (en) 2014-05-16 2021-03-30 Cytonome/St, Llc Thermal activated microfluidic switching
CN106999933B (zh) * 2014-11-19 2019-10-18 Imec 非营利协会 微泡产生器装置、系统及其制造方法
EP3250912A4 (en) * 2015-01-30 2018-10-10 Hewlett-Packard Development Company, L.P. Microfluidic sensing
EP3259579B1 (en) 2015-02-19 2022-09-14 1087 Systems, Inc. Scanning infrared measurement system
US11982611B2 (en) 2017-03-20 2024-05-14 Nanocellect Biomedical, Inc. Systems, apparatuses, and methods for cell sorting and flow cytometry
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Also Published As

Publication number Publication date
CA2651250A1 (en) 2007-11-15
US20080087584A1 (en) 2008-04-17
CA2651250C (en) 2016-06-28
AU2007248494B2 (en) 2012-11-08
WO2007130647A3 (en) 2008-11-13
EP2026912A2 (en) 2009-02-25
JP5059851B2 (ja) 2012-10-31
IL195116A (en) 2013-01-31
IL195116A0 (en) 2009-09-22
EP2026912B1 (en) 2013-07-10
US8863962B2 (en) 2014-10-21
KR20090024691A (ko) 2009-03-09
JP2009536032A (ja) 2009-10-08
CN101460260A (zh) 2009-06-17
WO2007130647A2 (en) 2007-11-15
AU2007248494A1 (en) 2007-11-15
US8123044B2 (en) 2012-02-28
US20120138513A1 (en) 2012-06-07

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: CYTONOME/ST, LLC (US)

Free format text: TRANSFERIDO DE: CYTONOME, INC.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 4A E 5A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 4A E 5A ANUIDADES.