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BRPI0612931B8 - composição para aplicação na pele - Google Patents

composição para aplicação na pele

Info

Publication number
BRPI0612931B8
BRPI0612931B8 BRPI0612931A BRPI0612931A BRPI0612931B8 BR PI0612931 B8 BRPI0612931 B8 BR PI0612931B8 BR PI0612931 A BRPI0612931 A BR PI0612931A BR PI0612931 A BRPI0612931 A BR PI0612931A BR PI0612931 B8 BRPI0612931 B8 BR PI0612931B8
Authority
BR
Brazil
Prior art keywords
skin
composition
patient
application
biocide
Prior art date
Application number
BRPI0612931A
Other languages
English (en)
Inventor
Kritzler Steven
Original Assignee
Novapharm Res Australia Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2005902493A external-priority patent/AU2005902493A0/en
Application filed by Novapharm Res Australia Pty Ltd filed Critical Novapharm Res Australia Pty Ltd
Publication of BRPI0612931A2 publication Critical patent/BRPI0612931A2/pt
Publication of BRPI0612931B1 publication Critical patent/BRPI0612931B1/pt
Publication of BRPI0612931B8 publication Critical patent/BRPI0612931B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/327—Peroxy compounds, e.g. hydroperoxides, peroxides, peroxyacids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

composição para aplicação na pele e método para preparar um paciente para cirurgia. composição para aplicação na pele, compreendendo um biocida ou combinação de biocidas (tais como clorexidina, fenóis halogenados, compostos de amônio quaternário; iodopovidona; piridinotiona de zinco; álcoóis, etc.) e pelo menos um veículo transcutâneo (por exemplo alquil metil sulfóxidos, alquil pirrolidonas, glicóis, glicol éteres, e glicol ésteres) eficazes para transportar o biocida até um microorganismo "residente" sub-epidérmico. também um método para preparar um paciente para cirurgia compreendendo a etapa de tratar uma área da pele do paciente no ou nas adjacências do local de uma incisão cirúrgica pretendida com uma composição eficaz para exterminar mais de 93% de microorganismos tanto "transitórios" como "residentes".
BRPI0612931A 2005-05-16 2006-04-28 composição para aplicação na pele BRPI0612931B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2005902493A AU2005902493A0 (en) 2005-05-16 Method and composition for use in preparation of a patient for surgery
AU2005902493 2005-05-16
PCT/AU2006/000553 WO2006122345A1 (en) 2005-05-16 2006-04-28 Method and composition for use in preparation of a patient for surgery

Publications (3)

Publication Number Publication Date
BRPI0612931A2 BRPI0612931A2 (pt) 2010-12-07
BRPI0612931B1 BRPI0612931B1 (pt) 2020-09-01
BRPI0612931B8 true BRPI0612931B8 (pt) 2021-05-25

Family

ID=37430837

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0612931A BRPI0612931B8 (pt) 2005-05-16 2006-04-28 composição para aplicação na pele

Country Status (13)

Country Link
US (2) US20080175811A1 (pt)
EP (1) EP1887864B1 (pt)
JP (2) JP2008540581A (pt)
KR (1) KR101413138B1 (pt)
CN (1) CN101175404B (pt)
BR (1) BRPI0612931B8 (pt)
CA (1) CA2608344C (pt)
ES (1) ES2785999T3 (pt)
MX (1) MX2007014372A (pt)
MY (1) MY162625A (pt)
TW (1) TWI417046B (pt)
WO (1) WO2006122345A1 (pt)
ZA (1) ZA200710387B (pt)

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Publication number Priority date Publication date Assignee Title
BRPI0819417A2 (pt) * 2007-12-17 2015-03-17 Novapharm Res Australia "composição que não mancha que é bactericida, fungicida e viricida"
WO2009091622A1 (en) 2008-01-18 2009-07-23 Dow Global Technologies Inc. Method to enhance aqueous solubility of poorly soluble actives using methoxypolyethylene glycol
TW200932107A (en) * 2008-01-18 2009-08-01 Dow Global Technologies Inc Stable, low VOC, low viscous biocidal formulations and method of making such formulations
JP5189402B2 (ja) * 2008-04-30 2013-04-24 株式会社マンダム 抗菌剤組成物及び防臭剤用組成物
WO2012034032A2 (en) * 2010-09-10 2012-03-15 The Board Of Regents Of Unbiversity Of Texas System Antimicrobial solutions
IN2014CN03706A (pt) * 2011-11-16 2015-10-09 3M Innovative Properties Co
JP6122035B2 (ja) * 2012-02-17 2017-04-26 ヴェローチェ・バイオファーマ・エルエルシー 皮膚および爪の治療のための抗真菌組成物
CA2877121A1 (en) 2012-06-18 2013-12-27 Vi-Jon, Inc. Sanitizer compositions comprising alcohol and an antimicrobial efficacy enhancer
CN102988236B (zh) * 2012-11-30 2015-06-24 哈尔滨医科大学 一种神经外科术前头部皮肤准备时所用备皮液及其制备方法和应用
EP2934121B1 (en) * 2012-12-24 2020-02-05 Novapharm Research (Australia) Pty Ltd Improved antimicrobial compositions
DE102014115080A1 (de) 2014-10-16 2016-04-21 Schülke & Mayr GmbH Verwendung von Fettsäureester zur Verbesserung der antimikrobiellen Wirksamkeit eines alkoholischen Desinfektionsmittels
EP3247365A4 (en) * 2015-01-20 2018-08-01 Veloce BioPharma LLC Novel iodophor composition and methods of use
WO2016141450A1 (en) * 2015-03-10 2016-09-15 Covalon Technologies Inc. Method for local reduction of microbial skin flora
CN108472505A (zh) * 2015-12-22 2018-08-31 3M创新有限公司 用于孢子移除的方法
CN108498535A (zh) * 2018-04-04 2018-09-07 哈尔滨快好药业有限公司 一种用于治疗皮肤及黏膜感染的聚维酮碘药物组合物及其制备方法和应用
BR102020024967A2 (pt) * 2020-12-07 2022-06-21 União Brasileira De Educação E Assistência - Mantenedora Da Pucrs Composição antimicrobiana para uso tópico e/ou externo
CN116407489A (zh) * 2021-12-29 2023-07-11 杜克有限责任公司 一种水溶性聚维酮碘凝胶、其制备方法及应用
WO2023129596A2 (en) * 2021-12-29 2023-07-06 Dukal, Llc Povidone iodine solution and gel, preparation method and application thereof

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Also Published As

Publication number Publication date
EP1887864A4 (en) 2012-12-19
JP2013173758A (ja) 2013-09-05
EP1887864B1 (en) 2020-02-12
MY162625A (en) 2017-06-30
TWI417046B (zh) 2013-12-01
KR20080019610A (ko) 2008-03-04
CN101175404B (zh) 2013-03-27
WO2006122345A1 (en) 2006-11-23
KR101413138B1 (ko) 2014-07-01
TW200721974A (en) 2007-06-16
US20110117048A1 (en) 2011-05-19
JP2008540581A (ja) 2008-11-20
EP1887864A1 (en) 2008-02-20
US20080175811A1 (en) 2008-07-24
CN101175404A (zh) 2008-05-07
MX2007014372A (es) 2008-02-07
CA2608344A1 (en) 2006-11-23
BRPI0612931B1 (pt) 2020-09-01
BRPI0612931A2 (pt) 2010-12-07
JP5892969B2 (ja) 2016-03-23
ES2785999T3 (es) 2020-10-08
US9511017B2 (en) 2016-12-06
CA2608344C (en) 2017-07-04
ZA200710387B (en) 2008-12-31

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