BRPI0612580A8 - glicinamidas substituídas, processo para a sua preparação e uso da mesma como medicamentos - Google Patents
glicinamidas substituídas, processo para a sua preparação e uso da mesma como medicamentosInfo
- Publication number
- BRPI0612580A8 BRPI0612580A8 BRPI0612580A BRPI0612580A BRPI0612580A8 BR PI0612580 A8 BRPI0612580 A8 BR PI0612580A8 BR PI0612580 A BRPI0612580 A BR PI0612580A BR PI0612580 A BRPI0612580 A BR PI0612580A BR PI0612580 A8 BRPI0612580 A8 BR PI0612580A8
- Authority
- BR
- Brazil
- Prior art keywords
- substituted glycine
- medicines
- glycine amides
- preparation
- amides
- Prior art date
Links
- BEBCJVAWIBVWNZ-UHFFFAOYSA-N glycinamide Chemical class NCC(N)=O BEBCJVAWIBVWNZ-UHFFFAOYSA-N 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 3
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
glicinamidas substituidas, seus sais fisiologicamente aceitáveis e seu uso, composições farmacêuticas, bem como seu processo de preparação. a presente invenção refere-se a novas glicinamidas substituidas de fórmula geral (1) na qual d, m, r^3^, r^4^ e r^5^ são definidos conforme indicados na descrição, os tautômeros, enanciômeros, diastereômeros, misturas e sais dos mesmos, especialmente os sais fisiologicamente aceitáveis dos mesmos com ácidos ou bases inorgânicas ou orgânicas, que são fornecidos com características valiosas.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05014270.2 | 2005-06-30 | ||
| EP05014270 | 2005-06-30 | ||
| PCT/EP2006/063611 WO2007003536A1 (de) | 2005-06-30 | 2006-06-28 | Substituierte glycinamide mit antithrombotischer und faktor xa-inhibierender wirkung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0612580A2 BRPI0612580A2 (pt) | 2010-11-23 |
| BRPI0612580A8 true BRPI0612580A8 (pt) | 2017-12-26 |
Family
ID=35907001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0612580A BRPI0612580A8 (pt) | 2005-06-30 | 2006-06-28 | glicinamidas substituídas, processo para a sua preparação e uso da mesma como medicamentos |
Country Status (32)
| Country | Link |
|---|---|
| US (3) | US20100216769A1 (pt) |
| EP (1) | EP1899330B9 (pt) |
| JP (1) | JP4768016B2 (pt) |
| KR (1) | KR101321722B1 (pt) |
| CN (1) | CN101213195B (pt) |
| AR (1) | AR054627A1 (pt) |
| AT (1) | ATE489381T1 (pt) |
| AU (1) | AU2006265216B2 (pt) |
| BR (1) | BRPI0612580A8 (pt) |
| CA (1) | CA2613059C (pt) |
| CY (1) | CY1111627T1 (pt) |
| DE (1) | DE502006008392D1 (pt) |
| DK (1) | DK1899330T3 (pt) |
| EA (1) | EA015188B1 (pt) |
| EC (1) | ECSP078058A (pt) |
| ES (1) | ES2357029T3 (pt) |
| HR (1) | HRP20110044T2 (pt) |
| IL (1) | IL188323A (pt) |
| MX (1) | MX2007016253A (pt) |
| MY (1) | MY145883A (pt) |
| NO (1) | NO340670B1 (pt) |
| NZ (1) | NZ565440A (pt) |
| PE (1) | PE20070171A1 (pt) |
| PL (1) | PL1899330T3 (pt) |
| PT (1) | PT1899330E (pt) |
| RS (1) | RS51572B (pt) |
| SG (1) | SG163540A1 (pt) |
| SI (1) | SI1899330T1 (pt) |
| TW (1) | TWI392495B (pt) |
| UA (1) | UA94910C2 (pt) |
| WO (1) | WO2007003536A1 (pt) |
| ZA (1) | ZA200708525B (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1799684B1 (en) | 2004-10-04 | 2014-12-03 | Millennium Pharmaceuticals, Inc. | Lactam compounds useful as protein kinase inhibitors |
| PE20080145A1 (es) | 2006-03-21 | 2008-02-11 | Janssen Pharmaceutica Nv | Tetrahidro-pirimidoazepinas como moduladores de trpv1 |
| EP2094695A4 (en) * | 2006-07-20 | 2010-04-28 | Cascade Therapeutics Inc | TETRAHYDRO-5H-PYRIDO [2,3-D] AZEPINES AS 5-HT2C LIGANDS |
| PE20081834A1 (es) * | 2006-12-31 | 2009-01-16 | Boehringer Ingelheim Int | Proceso para la sintesis de derivados de acido 3-amino-tetrahidrofuran-3-carboxilico y uso de los mismos como medicamentos |
| EP1975165A1 (de) | 2007-03-27 | 2008-10-01 | Boehringer Ingelheim Pharma GmbH & Co. KG | Substituierte Pyrrolidinamide, deren Herstellung und deren Verwendung als Arzneimittel |
| WO2009063028A2 (en) * | 2007-11-15 | 2009-05-22 | Boehringer Ingelheim International Gmbh | Substituted amides, manufacturing and use thereof as medicaments |
| JP5562865B2 (ja) | 2007-12-17 | 2014-07-30 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Ｔｒｐｖ１のイミダゾロ−、オキサゾロ−、及びチアゾロピリミジン・モジュレーター |
| AR074487A1 (es) | 2008-12-05 | 2011-01-19 | Millennium Pharm Inc | Tiolactamas inhibidoras de proteinquinasas plk, composiciones farmaceuticas que las contienen y usos de las mismas para el tratamiento de trastornos proliferativos e inflamatorios, en particular cancer. |
| US20120015938A1 (en) * | 2009-02-17 | 2012-01-19 | Msd K.K. | 1,4-benzodiazepin-2-on derivatives |
| EP3248615A1 (en) | 2010-03-30 | 2017-11-29 | Mount Sinai School of Medicine of New York University | Influenza virus vaccines and uses thereof |
| CN104185476A (zh) | 2011-09-20 | 2014-12-03 | 西奈山医学院 | 流感病毒疫苗及其应用 |
| EP4154907A1 (en) | 2012-12-18 | 2023-03-29 | Icahn School of Medicine at Mount Sinai | Influenza virus vaccines and uses thereof |
| FI3102200T3 (fi) * | 2014-02-07 | 2023-05-31 | Exithera Pharmaceuticals Inc | Terapeuttisia yhdisteitä ja koostumuksia |
| CN105622511B (zh) * | 2014-11-03 | 2018-01-23 | 北京瑞都医药科技有限公司 | 一种减肥药物及其制备方法 |
| EP3078378B1 (en) | 2015-04-08 | 2020-06-24 | Vaiomer | Use of factor xa inhibitors for regulating glycemia |
| TWI823961B (zh) | 2018-07-05 | 2023-12-01 | 德商拜耳廠股份有限公司 | 噻吩基噁唑酮及類似物 |
| CN111196772B (zh) * | 2018-11-16 | 2022-09-30 | 沈阳化工研究院有限公司 | 一种芳酰氨基异丁酰衍生物及其应用 |
| PL4077317T3 (pl) | 2019-12-20 | 2024-11-04 | Bayer Aktiengesellschaft | Tienylooksazolony i analogi |
| WO2022096542A1 (en) | 2020-11-06 | 2022-05-12 | Boehringer Ingelheim International Gmbh | 2-[thiophen-2-yl)formamido]-n-(phenyl)-2-methylpropanamide derivatives and the use thereof as medicament |
| WO2025019631A1 (en) | 2023-07-19 | 2025-01-23 | Icahn School Of Medicine At Mount Sinai | Immunogenic compositions containing inactivated influenza a virus and cpg oligonucleotide adjuvant and uses thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1192132B1 (en) | 1999-06-14 | 2005-09-07 | Eli Lilly And Company | Serine protease inhibitors |
| DE19962924A1 (de) * | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| MXPA02009305A (es) * | 2000-03-21 | 2003-03-12 | Smithkline Beecham Corp | Inhibidores de proteasa. |
| DE10063008A1 (de) | 2000-12-16 | 2002-06-20 | Merck Patent Gmbh | Carbonsäureamidderivate |
| WO2002092563A2 (en) | 2001-05-17 | 2002-11-21 | Smithkline Beecham Corporation | Protease inhibitors |
| PE20040837A1 (es) | 2002-11-19 | 2004-12-24 | Takeda Chemical Industries Ltd | Compuestos de amina |
| JP2004300133A (ja) * | 2002-11-19 | 2004-10-28 | Takeda Chem Ind Ltd | アミン誘導体 |
| DE10254336A1 (de) | 2002-11-21 | 2004-06-03 | Merck Patent Gmbh | Carbonsäureamide |
| US7250415B2 (en) * | 2003-06-04 | 2007-07-31 | Bristol-Myers Squibb Company | 1,1-Disubstitutedcycloalkyl-, glycinamidyl-, sulfonyl-amidino-, and tetrahydropyrimidinyl-containing diaminoalkyl, β-aminoacids, α-aminoacids and derivatives thereof as factor Xa inhibitors |
| WO2005111013A1 (de) | 2004-05-13 | 2005-11-24 | Boehringer Ingelheim International Gmbh | Substituierte thiophen-2-carbonsäureamide, deren herstellung und deren verwendung als arzneimittel |
| BRPI0510019A (pt) * | 2004-05-13 | 2007-09-25 | Boehringer Ingelheim Int | amidas de ácido tiofenocarboxìlico substituìdas, sua preparação e seu uso como medicamento |
| JP2007537181A (ja) * | 2004-05-13 | 2007-12-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 置換されたチオフェン−カルボン酸アミド、医薬品の形態におけるこれらの製造及び使用 |
| DE102004047840A1 (de) | 2004-09-29 | 2006-03-30 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue substituierte Thiophencarbonsäureamide, deren Herstellung und deren Verwendung als Arzneimittel |
| PE20081834A1 (es) | 2006-12-31 | 2009-01-16 | Boehringer Ingelheim Int | Proceso para la sintesis de derivados de acido 3-amino-tetrahidrofuran-3-carboxilico y uso de los mismos como medicamentos |
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2006
- 2006-06-27 PE PE2006000745A patent/PE20070171A1/es not_active Application Discontinuation
- 2006-06-28 MX MX2007016253A patent/MX2007016253A/es active IP Right Grant
- 2006-06-28 DK DK06763910.4T patent/DK1899330T3/da active
- 2006-06-28 PL PL06763910T patent/PL1899330T3/pl unknown
- 2006-06-28 EP EP06763910A patent/EP1899330B9/de active Active
- 2006-06-28 ES ES06763910T patent/ES2357029T3/es active Active
- 2006-06-28 UA UAA200800769A patent/UA94910C2/ru unknown
- 2006-06-28 US US11/993,426 patent/US20100216769A1/en not_active Abandoned
- 2006-06-28 RS RS20110015A patent/RS51572B/en unknown
- 2006-06-28 KR KR1020087002478A patent/KR101321722B1/ko not_active Expired - Fee Related
- 2006-06-28 AT AT06763910T patent/ATE489381T1/de active
- 2006-06-28 AU AU2006265216A patent/AU2006265216B2/en not_active Ceased
- 2006-06-28 JP JP2008517518A patent/JP4768016B2/ja not_active Expired - Fee Related
- 2006-06-28 SI SI200630915T patent/SI1899330T1/sl unknown
- 2006-06-28 DE DE502006008392T patent/DE502006008392D1/de active Active
- 2006-06-28 PT PT06763910T patent/PT1899330E/pt unknown
- 2006-06-28 SG SG201004677-9A patent/SG163540A1/en unknown
- 2006-06-28 MY MYPI20063092A patent/MY145883A/en unknown
- 2006-06-28 NZ NZ565440A patent/NZ565440A/en not_active IP Right Cessation
- 2006-06-28 BR BRPI0612580A patent/BRPI0612580A8/pt not_active Application Discontinuation
- 2006-06-28 WO PCT/EP2006/063611 patent/WO2007003536A1/de active Application Filing
- 2006-06-28 CN CN2006800242678A patent/CN101213195B/zh not_active Expired - Fee Related
- 2006-06-28 CA CA2613059A patent/CA2613059C/en not_active Expired - Fee Related
- 2006-06-28 EA EA200702620A patent/EA015188B1/ru not_active IP Right Cessation
- 2006-06-28 HR HR20110044T patent/HRP20110044T2/hr unknown
- 2006-06-29 TW TW095123603A patent/TWI392495B/zh not_active IP Right Cessation
- 2006-06-30 AR ARP060102825A patent/AR054627A1/es active IP Right Grant
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2007
- 2007-10-05 ZA ZA200708525A patent/ZA200708525B/xx unknown
- 2007-10-11 NO NO20075186A patent/NO340670B1/no not_active IP Right Cessation
- 2007-12-20 IL IL188323A patent/IL188323A/en not_active IP Right Cessation
- 2007-12-27 EC EC2007008058A patent/ECSP078058A/es unknown
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2011
- 2011-02-16 CY CY20111100202T patent/CY1111627T1/el unknown
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2013
- 2013-03-05 US US13/785,176 patent/US9062034B2/en active Active
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2015
- 2015-05-19 US US14/716,227 patent/US9676781B2/en active Active
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