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BRPI0612268A2 - Ácido nucleico isolado, vetor de expressço, mÉtodos para produzir um rna genâmico da influenza, para produzir um vÍrus da influenza recombinante, para gerar um vÍrus de rna segmentado de filamento negativo recombinante nas cÉlulas caninas cultivadas e para gerar partÍculas virais da influenza infecciosa em cÉlulas caninas cultivadas, cÉlula, e, vÍrus - Google Patents

Ácido nucleico isolado, vetor de expressço, mÉtodos para produzir um rna genâmico da influenza, para produzir um vÍrus da influenza recombinante, para gerar um vÍrus de rna segmentado de filamento negativo recombinante nas cÉlulas caninas cultivadas e para gerar partÍculas virais da influenza infecciosa em cÉlulas caninas cultivadas, cÉlula, e, vÍrus

Info

Publication number
BRPI0612268A2
BRPI0612268A2 BRPI0612268-0A BRPI0612268A BRPI0612268A2 BR PI0612268 A2 BRPI0612268 A2 BR PI0612268A2 BR PI0612268 A BRPI0612268 A BR PI0612268A BR PI0612268 A2 BRPI0612268 A2 BR PI0612268A2
Authority
BR
Brazil
Prior art keywords
virus
influenza
producing
generating
cells
Prior art date
Application number
BRPI0612268-0A
Other languages
English (en)
Inventor
Gregory Duke
George Kemble
James Young
Zhaoti Wang
Original Assignee
Medimmune Vaccines Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Vaccines Inc filed Critical Medimmune Vaccines Inc
Publication of BRPI0612268A2 publication Critical patent/BRPI0612268A2/pt

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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C12N9/10—Transferases (2.)
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/008—Vector systems having a special element relevant for transcription cell type or tissue specific enhancer/promoter combination

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  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
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Abstract

ÁCIDO NUCLEICO ISOLADO, VETOR DE EXPRESSçO, MÉTODOS PARA PRODUZIR UM RNA GENâMICO DA INIFLUENZA, PARA PRODUZIR UM VÍRUS DA INFLUENZA RECOMBINANTE, PARA GERAR UM VÍRUS DE RNA SEGMENTADO DE FILAMENTO NEGATIVO RECOMBINANTE NAS CÉLULAS CANINAS CULTIVADAS E PARA GERAR PARTÍCULAS VIRAIS DA INFLUENZA INFECCIOSA EM CÉLULAS CANiNAS CULTIVADAS, CÉLULA, E, VÍRUS. A presente invenção fornece novas sequências de ácido nucleico reguladoras da polimerase 1 canina, úteis para a expressão das sequências de ácido nucleico em células caninas tais como as células MDCK. A invenção ainda fornece vetores de expressão e células compreendendo tais ácidos nucleicos, bem como métodos de uso de tais ácidos nucleicos para produzir vírus da influenza, incluindo os vírus da influenza infecciosa.
BRPI0612268-0A 2005-06-21 2006-06-20 Ácido nucleico isolado, vetor de expressço, mÉtodos para produzir um rna genâmico da influenza, para produzir um vÍrus da influenza recombinante, para gerar um vÍrus de rna segmentado de filamento negativo recombinante nas cÉlulas caninas cultivadas e para gerar partÍculas virais da influenza infecciosa em cÉlulas caninas cultivadas, cÉlula, e, vÍrus BRPI0612268A2 (pt)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US69296505P 2005-06-21 2005-06-21
US69297805P 2005-06-21 2005-06-21
US69955605P 2005-07-15 2005-07-15
US69955505P 2005-07-15 2005-07-15
US70200605P 2005-07-22 2005-07-22
US79352206P 2006-04-19 2006-04-19
US79352506P 2006-04-19 2006-04-19
PCT/US2006/023867 WO2007002008A2 (en) 2005-06-21 2006-06-20 Methods and compositions for expressing negative-sense viral rna in canine cells

Publications (1)

Publication Number Publication Date
BRPI0612268A2 true BRPI0612268A2 (pt) 2009-01-27

Family

ID=37595721

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0612268-0A BRPI0612268A2 (pt) 2005-06-21 2006-06-20 Ácido nucleico isolado, vetor de expressço, mÉtodos para produzir um rna genâmico da influenza, para produzir um vÍrus da influenza recombinante, para gerar um vÍrus de rna segmentado de filamento negativo recombinante nas cÉlulas caninas cultivadas e para gerar partÍculas virais da influenza infecciosa em cÉlulas caninas cultivadas, cÉlula, e, vÍrus

Country Status (11)

Country Link
US (4) US20060286591A1 (pt)
EP (2) EP1917352A4 (pt)
JP (2) JP2008546408A (pt)
KR (2) KR20080024212A (pt)
AU (2) AU2006262380A1 (pt)
BR (1) BRPI0612268A2 (pt)
CA (2) CA2613284A1 (pt)
IL (1) IL188202A0 (pt)
NO (1) NO20080358L (pt)
RU (1) RU2008101367A (pt)
WO (2) WO2007002007A2 (pt)

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KR20080024212A (ko) 2005-06-21 2008-03-17 메드이뮨 백신즈 인코포레이티드 개의 세포에서 네거티브 센스 바이러스 ｒｎａ를발현시키기 위한 방법 및 조성물
US7790434B2 (en) * 2005-06-21 2010-09-07 Medimmune, Llc Methods and compositions for expressing negative-sense viral RNA in canine cells
RU2457250C2 (ru) * 2006-04-19 2012-07-27 Медиммуне, Ллк Способы и композиции для экспрессии антисмысловой вирусной рнк в клетках собаки

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AU2006262381A1 (en) 2007-01-04
US20110045586A1 (en) 2011-02-24
WO2007002007A2 (en) 2007-01-04
KR20080025171A (ko) 2008-03-19
EP1917361A2 (en) 2008-05-07
WO2007002008A3 (en) 2007-12-27
US20060286591A1 (en) 2006-12-21
CA2613284A1 (en) 2007-01-04
AU2006262380A1 (en) 2007-01-04
US20120329150A1 (en) 2012-12-27
WO2007002008A2 (en) 2007-01-04
NO20080358L (no) 2008-03-03
US8278433B2 (en) 2012-10-02
JP2008543331A (ja) 2008-12-04
WO2007002007A8 (en) 2007-05-10
KR20080024212A (ko) 2008-03-17
CA2613283A1 (en) 2007-01-04
EP1917352A4 (en) 2009-03-25
EP1917361A4 (en) 2009-07-29
IL188202A0 (en) 2008-03-20
JP2008546408A (ja) 2008-12-25
RU2008101367A (ru) 2009-08-10
US20100203641A1 (en) 2010-08-12

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