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BRPI0607765A2 - pirazolopirimidinas - Google Patents

pirazolopirimidinas

Info

Publication number
BRPI0607765A2
BRPI0607765A2 BRPI0607765-0A BRPI0607765A BRPI0607765A2 BR PI0607765 A2 BRPI0607765 A2 BR PI0607765A2 BR PI0607765 A BRPI0607765 A BR PI0607765A BR PI0607765 A2 BRPI0607765 A2 BR PI0607765A2
Authority
BR
Brazil
Prior art keywords
pyrazolopyrimidines
pirazolopyrimidines
formula
preparation
description
Prior art date
Application number
BRPI0607765-0A
Other languages
English (en)
Inventor
Stefan Herrmann
Olaf Gebauer
Herbert Gayer
Stefan Hillebrand
Ulrich Heinemann
Oliver Guth
Kerstin Ilg
Ronald Ebbert
Ulrike Wachendorff-Neumann
Karl-Heinz Kuck
Thomas Seitz
Peter Dahmen
Horst-Peter Antonicek
Original Assignee
Bayer Cropscience Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag filed Critical Bayer Cropscience Ag
Publication of BRPI0607765A2 publication Critical patent/BRPI0607765A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PIRAZOLOPIRIMIDINAS. A presente invenção refere-se a pirazolopirimidinas da fórmula (I) na qual R^ 1^, R^ 2^, R^ 3^, R^ 4^, R^ 5^ e X têm os significados indicados na descrição, processo para sua preparação e seu emprego para o controle de microor- ganismos indesejados.
BRPI0607765-0A 2005-02-17 2006-02-07 pirazolopirimidinas BRPI0607765A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005007534A DE102005007534A1 (de) 2005-02-17 2005-02-17 Pyrazolopyrimidine
PCT/EP2006/001064 WO2006087120A2 (de) 2005-02-17 2006-02-07 Pyrazolopyrimidine

Publications (1)

Publication Number Publication Date
BRPI0607765A2 true BRPI0607765A2 (pt) 2009-10-06

Family

ID=36793966

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0607765-0A BRPI0607765A2 (pt) 2005-02-17 2006-02-07 pirazolopirimidinas

Country Status (16)

Country Link
US (1) US7781439B2 (pt)
EP (1) EP1853607A2 (pt)
JP (1) JP2008530155A (pt)
KR (1) KR20070103473A (pt)
CN (1) CN101120000B (pt)
AR (1) AR052913A1 (pt)
AU (1) AU2006215858A1 (pt)
BR (1) BRPI0607765A2 (pt)
CA (1) CA2597833A1 (pt)
DE (1) DE102005007534A1 (pt)
EA (1) EA200701707A1 (pt)
IL (1) IL185092A0 (pt)
MX (1) MX2007010045A (pt)
TW (1) TW200640926A (pt)
WO (1) WO2006087120A2 (pt)
ZA (1) ZA200706734B (pt)

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DE102006039255A1 (de) * 2006-08-17 2008-02-21 Bayer Cropscience Ag Insektizide heterocyclische Carbonsäurederivate
EP2014661A1 (de) * 2007-06-13 2009-01-14 Bayer CropScience AG Heterocyclisch substituierte Heterocyclyl-carbonsäurederivate
GB0712653D0 (en) 2007-06-28 2007-08-08 Syngenta Ltd Novel herbicides
GB0717082D0 (en) 2007-09-03 2007-10-10 Syngenta Ltd Novel herbicides
WO2010045615A2 (en) 2008-10-16 2010-04-22 Cenomed Biosciences, Llc Treatment of organophosphate exposure with ocinaplon
JP6154746B2 (ja) * 2010-12-08 2017-06-28 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ グルコセレブロシダーゼ活性剤としての置換ピラゾロピリミジン類
JP2014517079A (ja) 2011-06-22 2014-07-17 バーテックス ファーマシューティカルズ インコーポレイテッド Ａｔｒキナーゼ阻害剤として有用な化合物
ES2946360T3 (es) 2012-12-07 2023-07-17 Vertex Pharma Pirazolo[1,5-a]pirimidinas útiles como inhibidores de ATR quinasa para el tratamiento de enfermedades de cáncer
JP2016512239A (ja) 2013-03-15 2016-04-25 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ Ａｔｒキナーゼの阻害剤として有用な化合物
JP2016512816A (ja) 2013-03-15 2016-05-09 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ Ａｔｒキナーゼの阻害剤として有用な化合物
US9663519B2 (en) 2013-03-15 2017-05-30 Vertex Pharmaceuticals Incorporated Compounds useful as inhibitors of ATR kinase
HRP20192183T1 (hr) 2013-12-06 2020-02-21 Vertex Pharmaceuticals Inc. Spoj 2-amino-6-fluoro-n-[5-fluoro-piridin-3-il]pirazolo[1,5-a]pirimidin-3-karboksamida koristan kao inhibitor atr kinase, njegova priprava, različiti kruti oblici te njegovi radioaktivno označeni derivati
LT3152212T (lt) 2014-06-05 2020-05-11 Vertex Pharmaceuticals Inc. Radioaktyviai žymėti 2-amino-6-fluor-n-[5-fluor-piridin-il]- pirazolo[1,5-a]pirimidin-3-karboksamido junginio dariniai, naudingi kaip atr kinazės inhibitoriai, minėto junginio gamybos būdas ir jo skirtingos kietos formos
NZ727399A (en) 2014-06-17 2022-07-29 Vertex Pharma Method for treating cancer using a combination of chk1 and atr inhibitors
CN107001379B (zh) 2014-11-06 2022-11-01 Bial研发投资股份有限公司 取代的吡唑并[1,5-a]嘧啶以及它们在治疗医学障碍中的用途
KR102678021B1 (ko) 2015-09-30 2024-06-26 버텍스 파마슈티칼스 인코포레이티드 Dna 손상제와 병용되는, atr 저해제를 포함하는 암 치료용 약제학적 조성물
EP3440080A4 (en) 2016-04-06 2020-01-22 Lysosomal Therapeutics Inc. PYRAZOLO [1,5-A] PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
JP7034935B2 (ja) 2016-04-06 2022-03-14 リソソーマル・セラピューティクス・インコーポレイテッド ピロロ［１，２－ａ］ピリミジニルカルボキサミド化合物および医学的障害の処置におけるその使用
EP3440083A4 (en) 2016-04-06 2019-09-18 Lysosomal Therapeutics Inc. IMIDAZO [1,5-A] PYRIMIDINYL-CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDER
BR112018072552A8 (pt) 2016-05-05 2023-03-14 Lysosomal Therapeutics Inc Compostos de imidazo [1,2-b]piridazinas e imidazo [1,5-b] piridazinas substituídas, composição farmacêutica que os compreende e seu uso no tratamento de distúrbios médicos
RS65838B1 (sr) 2017-07-28 2024-09-30 Takeda Pharmaceuticals Co Tyk2 inhibitori i njihova upotreba
MX2021004769A (es) 2018-10-30 2021-08-24 Kronos Bio Inc Compuestos, composiciones, y metodos para modular la actividad cdk9.
CN113287620B (zh) * 2021-06-18 2021-11-19 浙江大学 1H-吡唑并[3,4-d]嘧啶类化合物在制备禾谷镰刀菌杀菌剂中的应用

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US2444605A (en) * 1945-12-15 1948-07-06 Gen Aniline & Film Corp Stabilizers for photographic emulsions
US3515715A (en) 1967-01-23 1970-06-02 Eastman Kodak Co Quaternized pyrazolylazo dyes
US3634391A (en) 1969-07-25 1972-01-11 Eastman Kodak Co Pyrazolyl-azo-indole dyestuffs
US4838925A (en) * 1986-04-25 1989-06-13 E. I. Du Pont De Nemours And Company Heterocyclic acyl sulfonamides
DE3825043A1 (de) * 1988-07-20 1990-02-15 Schering Ag 3-methylsulfonyl-pyrazolo(1,5-a)pyrimidin-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung als mittel mit herbizider, pflanzenwuchsregulierender und fungizider wirkung
IL131912A (en) 1998-09-25 2005-12-18 American Cyanamid Co Process for preparing halogenated phenylmalonates
US6156925A (en) 1998-09-25 2000-12-05 American Cyanamid Company Process for the preparation of halogenated phenylmaloates
DE60015817T2 (de) 2000-12-11 2005-03-17 Basf Ag 6-phenyl-pyrazolpyrimidine
ES2283626T3 (es) 2001-07-26 2007-11-01 Basf Aktiengesellschaft 7-aminotriazolpirimidinas para controlar hongos nocivos.
NZ518658A (en) * 2002-04-30 2004-10-29 Lionel Evans Method of water treatment
DE10223917A1 (de) 2002-05-29 2003-12-11 Bayer Cropscience Ag Pyrazolopyrimidine
FR2841982B1 (fr) 2002-07-03 2005-03-25 Inst Francais Du Petrole Capteur de pression a fibre optique compense en temperature
JP2006502992A (ja) 2002-07-17 2006-01-26 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー マトリックスメタロプロテイナーゼ−１３のアロステリック阻害剤とセレコキシブ又はバルデコキシブとの組合せ
JP4564485B2 (ja) 2003-02-28 2010-10-20 帝人ファーマ株式会社 ピラゾロ［１，５−ａ］ピリミジン誘導体
KR20060017529A (ko) 2003-06-03 2006-02-23 바스프 악티엔게젤샤프트 치환된 피라졸로피리미딘, 그의 제조 방법, 병원성 진균의방제를 위한 그의 용도 및 상기 화합물을 함유하는 제제
KR20060027809A (ko) 2003-06-27 2006-03-28 바이엘 크롭사이언스 아게 피라졸로피리미딘
DE10357567A1 (de) * 2003-12-10 2005-07-07 Bayer Cropscience Ag Pyrazolopyrimidine
DE10357568A1 (de) * 2003-12-10 2005-07-07 Bayer Cropscience Ag Pyrazolopyrimidine
DE10357565A1 (de) 2003-12-10 2005-07-07 Bayer Cropscience Ag Pyrazolopyrimidine
DE10357569A1 (de) 2003-12-10 2005-07-07 Bayer Cropscience Ag Pyrazolopyrimidine
DE102004008807A1 (de) * 2004-02-20 2005-09-08 Bayer Cropscience Ag Pyrazolopyrimidine

Also Published As

Publication number Publication date
MX2007010045A (es) 2007-10-02
CA2597833A1 (en) 2006-08-24
US20080287463A1 (en) 2008-11-20
CN101120000B (zh) 2011-05-18
AR052913A1 (es) 2007-04-11
EP1853607A2 (de) 2007-11-14
CN101120000A (zh) 2008-02-06
IL185092A0 (en) 2007-12-03
WO2006087120A3 (de) 2006-12-14
TW200640926A (en) 2006-12-01
AU2006215858A1 (en) 2006-08-24
KR20070103473A (ko) 2007-10-23
EA200701707A1 (ru) 2008-02-28
JP2008530155A (ja) 2008-08-07
WO2006087120A8 (de) 2007-08-30
ZA200706734B (en) 2009-01-28
DE102005007534A1 (de) 2006-08-31
WO2006087120A2 (de) 2006-08-24
US7781439B2 (en) 2010-08-24

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2161 DE 05/06/2012.