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BRPI0520014A2 - emulsões oftálmicas estáveis de óleo-em-água com hialuronato de sódio para alìvio de olho seco - Google Patents

emulsões oftálmicas estáveis de óleo-em-água com hialuronato de sódio para alìvio de olho seco

Info

Publication number
BRPI0520014A2
BRPI0520014A2 BRPI0520014-8A BRPI0520014A BRPI0520014A2 BR PI0520014 A2 BRPI0520014 A2 BR PI0520014A2 BR PI0520014 A BRPI0520014 A BR PI0520014A BR PI0520014 A2 BRPI0520014 A2 BR PI0520014A2
Authority
BR
Brazil
Prior art keywords
dry eye
sodium hyaluronate
eye relief
stable oil
water
Prior art date
Application number
BRPI0520014-8A
Other languages
English (en)
Inventor
Zhi-Jian Yu
Stanley W Huth
Lauren L Crawford
James N Cook
Original Assignee
Advanced Medical Optics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Medical Optics Inc filed Critical Advanced Medical Optics Inc
Publication of BRPI0520014A2 publication Critical patent/BRPI0520014A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535—Perilla (beefsteak plant)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/55—Linaceae (Flax family), e.g. Linum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/141—Biguanides, e.g. chlorhexidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/141—Biguanides, e.g. chlorhexidine
    • A61L12/142—Polymeric biguanides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/143—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dispersion Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

EMULSõES OFTáLMICAS ESTáVEIS DE óLEO-EM-áGUA COM HIALURONATO DE SóDIO PARA ALìVIO DE OLHO SECO. A presente invenção refere-se a emulsões óleo-em-água que contêm um demulcente para o tratamento olho seco, como o hialuronato de sódio. As emulsões óleo-em-água são estáveis e possuem atividade antimicrobiana suficiente para serem utilizadas como soluções de desinfecção de lentes de contato.
BRPI0520014-8A 2005-04-04 2005-09-23 emulsões oftálmicas estáveis de óleo-em-água com hialuronato de sódio para alìvio de olho seco BRPI0520014A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/098,827 US20050196370A1 (en) 2003-03-18 2005-04-04 Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye
PCT/US2005/034055 WO2006107330A1 (en) 2005-04-04 2005-09-23 Stable ophthalmic oil-in-water emulsions with sodium hyaluronate for alleviating dry eye

Publications (1)

Publication Number Publication Date
BRPI0520014A2 true BRPI0520014A2 (pt) 2009-04-14

Family

ID=35501164

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0520014-8A BRPI0520014A2 (pt) 2005-04-04 2005-09-23 emulsões oftálmicas estáveis de óleo-em-água com hialuronato de sódio para alìvio de olho seco

Country Status (8)

Country Link
US (2) US20050196370A1 (pt)
EP (1) EP1868620A1 (pt)
JP (1) JP2008534680A (pt)
CN (1) CN101151038A (pt)
AU (1) AU2005330293A1 (pt)
BR (1) BRPI0520014A2 (pt)
CA (1) CA2605386A1 (pt)
WO (1) WO2006107330A1 (pt)

Families Citing this family (114)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6702949B2 (en) 1997-10-24 2004-03-09 Microdiffusion, Inc. Diffuser/emulsifier for aquaculture applications
US20110075507A1 (en) * 1997-10-24 2011-03-31 Revalesio Corporation Diffuser/emulsifier
US20060251685A1 (en) * 2003-03-18 2006-11-09 Zhi-Jian Yu Stable ophthalmic oil-in-water emulsions with Omega-3 fatty acids for alleviating dry eye
US20040185068A1 (en) * 2003-03-18 2004-09-23 Zhi-Jian Yu Self-emulsifying compositions, methods of use and preparation
AU2005304424A1 (en) * 2004-11-09 2006-05-18 Abbott Medical Optics Inc. Ophthalmic solution
ES2393675T3 (es) * 2005-07-13 2012-12-27 Santen Pharmaceutical Co., Ltd. Composición conservante para uso oftálmico
JP5014348B2 (ja) 2005-10-04 2012-08-29 アショーリアン、ジャムシッド スナック食品の製造方法及びそれにより製造される製品
US9615601B2 (en) 2005-10-04 2017-04-11 Jimmyash Llc Process for the controlled introduction of oil into food products
ES2678057T3 (es) 2005-10-04 2018-08-08 Jimmyash Llc Productos alimentarios fritos que tienen contenido reducido de grasa
US7745400B2 (en) * 2005-10-14 2010-06-29 Gregg Feinerman Prevention and treatment of ocular side effects with a cyclosporin
US9839667B2 (en) 2005-10-14 2017-12-12 Allergan, Inc. Prevention and treatment of ocular side effects with a cyclosporin
US20070087962A1 (en) * 2005-10-17 2007-04-19 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins
EP1968379A2 (en) * 2005-12-12 2008-09-17 Riolan Technologies, Inc. Compositions, methods and kits for removing debris from an ocular area
US8673297B2 (en) 2006-02-28 2014-03-18 Basf Corporation Chlorine dioxide based cleaner/sanitizer
US7767217B2 (en) 2006-03-14 2010-08-03 Foresight Biotherapeutics Ophthalmic compositions comprising povidone-iodine
US20070264226A1 (en) * 2006-05-10 2007-11-15 Karagoezian Hampar L Synergistically enhanced disinfecting solutions
US8088300B2 (en) * 2006-06-21 2012-01-03 Basf Corporation Stabilized composition for producing chlorine dioxide
US20080020064A1 (en) * 2006-07-21 2008-01-24 Advanced Vision Research Methods and compositions for the treatment of infection or infectious colonization of the eyelid, ocular surface, skin or ear
US8609148B2 (en) 2006-10-25 2013-12-17 Revalesio Corporation Methods of therapeutic treatment of eyes
US8445546B2 (en) 2006-10-25 2013-05-21 Revalesio Corporation Electrokinetically-altered fluids comprising charge-stabilized gas-containing nanostructures
US7919534B2 (en) 2006-10-25 2011-04-05 Revalesio Corporation Mixing device
US8784897B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of therapeutic treatment of eyes
AU2007349224B2 (en) 2006-10-25 2014-04-03 Revalesio Corporation Methods of wound care and treatment
AU2007308840C1 (en) * 2006-10-25 2014-09-25 Revalesio Corporation Methods of therapeutic treatment of eyes and other human tissues using an oxygen-enriched solution
US8784898B2 (en) 2006-10-25 2014-07-22 Revalesio Corporation Methods of wound care and treatment
WO2008074885A2 (en) * 2006-12-21 2008-06-26 Novagali Pharma Sa Process for manufacturing ophthalmic oil-in-water emulsions
JP5563745B2 (ja) * 2007-04-04 2014-07-30 大正製薬株式会社 点眼剤
EP1985298A1 (en) * 2007-04-24 2008-10-29 Azad Pharma AG Ophtalmic oil-in-water emulsions containing prostaglandins
US8609634B2 (en) 2007-05-16 2013-12-17 Mcneil-Ppc, Inc. Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods
US9579341B2 (en) * 2007-05-16 2017-02-28 Johnson & Johnson Consumer Inc. Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods
FR2916636B1 (fr) * 2007-05-29 2009-09-04 Octalia Technologies Vehicule sous forme d'une emulsion huile-dans-eau notamment destine a une utilisation ophtalmique ou dermocosmetique
US8759321B2 (en) * 2007-06-13 2014-06-24 Bausch & Lomb Incorporated Ophthalmic composition with hyaluronic acid and polymeric biguanide
US20090036404A1 (en) * 2007-08-02 2009-02-05 Macleod Steven K Ophthalmic compositions comprising a carboxyl-modified fructan or a salt thereof
US10125359B2 (en) 2007-10-25 2018-11-13 Revalesio Corporation Compositions and methods for treating inflammation
US9523090B2 (en) 2007-10-25 2016-12-20 Revalesio Corporation Compositions and methods for treating inflammation
US9745567B2 (en) 2008-04-28 2017-08-29 Revalesio Corporation Compositions and methods for treating multiple sclerosis
JP2009175731A (ja) * 2007-12-28 2009-08-06 Rohto Pharmaceut Co Ltd グリセリンおよびリン酸化合物を含有する亜塩素酸類化合物含有水性組成物
US8119112B2 (en) * 2008-01-31 2012-02-21 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid
US9096819B2 (en) * 2008-01-31 2015-08-04 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer
US20110046033A1 (en) * 2008-01-31 2011-02-24 Jinzhong Zhang Multipurpose Lens Care Solution with Benefits to Corneal Epithelial Barrier Function
US20090239775A1 (en) * 2008-03-19 2009-09-24 Collins Gary L Ophthalmic solutions displaying improved efficacy
CN102076327B (zh) 2008-05-01 2014-04-16 利发利希奥公司 治疗消化功能紊乱的组合物和方法
EP2285364B1 (en) 2008-05-07 2015-01-21 The Regents of The University of California Therapeutic replenishment and enrichment of ocular surface lubrication
US8506944B2 (en) * 2008-05-07 2013-08-13 The Regents Of The University Of California Replenishment and enrichment of ocular surface lubrication
US20100286010A1 (en) * 2008-09-03 2010-11-11 Erning Xia Ophthalmic Compositions with Hyaluronic Acid
US20100086512A1 (en) * 2008-10-02 2010-04-08 Rolf Schaefer Mucomimetic compositions and uses therefore
EP2385839B1 (en) * 2009-01-09 2014-11-26 The Schepens Eye Research Institute, Inc. Therapeutic compositions for treatment of corneal disorders
US20100233101A1 (en) 2009-02-13 2010-09-16 Micropure, Inc. Composition and method for the oxidative consumption of salivary biomolecules
US20100234319A1 (en) * 2009-03-11 2010-09-16 Abbott Medical Optics Inc. Complex of Polymeric Quaternary Ammonium and Anionic Polymers as a New Antimicrobial Agent for Ophthalmic Compositions
US8815292B2 (en) 2009-04-27 2014-08-26 Revalesio Corporation Compositions and methods for treating insulin resistance and diabetes mellitus
CA2762959A1 (en) * 2009-05-29 2010-12-02 Symatese Injectable combination of adrenergic receptor agonists with fillers, for decreasing skin reactions due to injection
JP5601805B2 (ja) * 2009-08-24 2014-10-08 キユーピー株式会社 経口用ドライアイ改善剤、ならびに前記経口用ドライアイ改善剤を含む食品組成物および医薬品組成物
US9717703B2 (en) 2009-10-16 2017-08-01 Glaxosmithkline Llc Emulsion and emulsion preconcentrate compositions comprising omega-3 fatty acids and uses thereof are disclosed
TWI478730B (zh) * 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
EP2511752B1 (en) * 2009-12-08 2014-10-15 Menicon Co., Ltd. Process for production of contact lens package
WO2011127139A2 (en) * 2010-04-07 2011-10-13 Allergan, Inc. Combinations of preservative compositions for ophthalmic formulations
BR112012028540A2 (pt) 2010-05-07 2016-07-26 Revalesio Corp composições e métodos para melhorar desempenho fisiológico e tempo de recuperação
KR20130091759A (ko) 2010-08-12 2013-08-19 레발레시오 코퍼레이션 타우병증의 치료를 위한 조성물 및 방법
IT1401922B1 (it) * 2010-09-09 2013-08-28 Ibsa Inst Biochimique Sa Processo per ottenere acido ialuronico a peso molecolare definito
ES2385995B2 (es) * 2011-01-10 2013-05-21 Universidade De Santiago De Compostela Nanocápsulas con cubierta polimérica
US9375401B2 (en) * 2012-02-24 2016-06-28 Bausch ÷ Lomb Incorporated Ophthalmic compositions with alkoxylated natural waxes
KR101211902B1 (ko) * 2012-04-30 2012-12-13 주식회사 휴온스 사이클로스포린 함유 무자극성 나노에멀젼 안약 조성물
US20140235554A1 (en) * 2013-02-12 2014-08-21 Brian Lawrence Ophthalmic formulation derived from silk protein
FR3002452B1 (fr) * 2013-02-28 2016-02-12 Dermaconcept Jmc Composition dermatologique antimicrobienne topique
US11179327B2 (en) * 2013-08-28 2021-11-23 Lenz Therapeutics, Inc. Compositions and methods for the treatment of presbyopia
US10959990B2 (en) * 2013-08-28 2021-03-30 Presbyopia Therapies, Inc Compositions and methods for the treatment of presbyopia
US10307408B2 (en) * 2013-08-28 2019-06-04 Presbyopia Therapies, LLC Contact lens compositions and methods for the treatment of presbyopia
US11344538B2 (en) * 2013-08-28 2022-05-31 Lenz Therapeutics, Inc. Methods for the treatment of myopia
US10617763B2 (en) * 2013-08-28 2020-04-14 Presbyopia Therapies, LLC Compositions and methods for the treatment of presbyopia
US10052313B2 (en) * 2013-08-28 2018-08-21 Presbyopia Therapies, LLC Compositions and methods for the treatment of presbyopia
EP3049119B1 (en) * 2013-09-27 2018-07-11 Novartis AG Compositions and methods for disinfecting and cleaning contact lenses
JP2014028865A (ja) * 2013-11-11 2014-02-13 Santen Sas 眼科用水中油型乳剤を製造する方法
CN103805069B (zh) * 2014-01-27 2016-03-02 欧普康视科技股份有限公司 一种角膜接触镜抛光液及其制备方法
WO2016029034A1 (en) 2014-08-20 2016-02-25 Silk Technologies, Ltd. Fibroin-derived protein composition
DK3229780T3 (en) 2014-12-12 2019-03-18 Alfa Intes Ind Terapeutica Splendore S R L Ophthalmic composition for use in the treatment of dry eye syndrome
US20180221278A1 (en) * 2015-02-24 2018-08-09 Ocugen, Inc. Prsustained release opthalmic formuation and methods for using the same
ES2936394T3 (es) * 2015-02-24 2023-03-16 Univ Illinois Métodos y composiciones para tratar la enfermedad del ojo seco y otros trastornos oculares
US9877964B2 (en) 2015-02-24 2018-01-30 Ocugen, Inc. Methods and compositions for treating dry eye disease and other eye disorders
US10751337B2 (en) * 2015-02-24 2020-08-25 Ocugen, Inc. Preservative free ocular compositions and methods for using the same for treating dry eye disease and other eye disorders
WO2016205069A1 (en) * 2015-06-18 2016-12-22 Presbyopia Therapies, LLC Compositions for the improvement of distance vision and the treatment of refractive errors of the eye
KR101635915B1 (ko) * 2016-02-15 2016-07-04 삼천당제약주식회사 사이클로스포린과 히알루론산 또는 이의 염을 포함하는 수용액 형태의 안과용 조성물
SG11201805799YA (en) * 2016-02-22 2018-08-30 Coopervision International Holding Company Lp Silicone hydrogel contact lenses having improved lubricity
JP2019519596A (ja) 2016-04-08 2019-07-11 コーネル・ユニバーシティーCornell University シルク由来タンパク質を使用して創傷治癒を増進する方法
MX2019001633A (es) 2016-08-12 2019-09-18 Silk Tech Ltd Proteina derivada de la seda para el tratamiento de la inflamacion.
CN107789657A (zh) * 2016-08-30 2018-03-13 欧普康视科技股份有限公司 一种硬性接触镜护理液
US10150056B2 (en) 2016-11-14 2018-12-11 Lilac Solutions, Inc. Lithium extraction with coated ion exchange particles
JP2020523406A (ja) 2017-05-19 2020-08-06 オクジェン アイエヌシー． 眼科用組成物および使用方法
IT201700068170A1 (it) * 2017-06-20 2018-12-20 Iromed Group S R L Composizione disinfettante per uso oftalmico
EP3661619A4 (en) 2017-08-02 2021-05-05 Lilac Solutions, Inc. LITHIUM EXTRACTION WITH POROUS ION EXCHANGE BEADS
CA3020197C (en) 2017-09-01 2024-06-04 Micropure, Inc. Aliphatic anionic compounds and oxidative compounds with improved stability and efficacy for use in pharmaceutical compositions
KR102691673B1 (ko) 2018-02-21 2024-08-06 알콘 인코포레이티드 지질-기재 안과용 에멀션
KR20200116526A (ko) 2018-02-28 2020-10-12 리락 솔루션즈, 인크. 리튬 추출을 위한 입자 트랩을 가진 이온 교환 반응기
CN110538091A (zh) 2018-05-29 2019-12-06 玫琳凯有限公司 局部用组合物和方法
US20210251970A1 (en) 2018-10-10 2021-08-19 Presbyopia Therapies Inc Compositions and methods for storage stable ophthalmic drugs
RU2692087C1 (ru) * 2018-11-27 2019-06-21 Илья Александрович Марков Глазные гелеобразные капли для лечения острых и хронических воспалительных заболеваний глаз, вызванных вирусными, бактериальными, аллергическими, метаболическими или травматическими факторами
EP3982930A1 (en) 2019-06-11 2022-04-20 SIFI S.p.A. Microemulsion compositions
US11944097B2 (en) 2019-07-01 2024-04-02 Aseptic Health, LLC Antimicrobial composition
US11969454B2 (en) * 2019-11-19 2024-04-30 Johnson & Johnson Surgical Vision, Inc. Compositions and methods for treating the eye
CN111248221A (zh) * 2020-02-13 2020-06-09 上海克琴科技有限公司 一种通过协效物稳定的长效型消毒剂
EP3919047A1 (en) * 2020-06-03 2021-12-08 AZAD Pharma AG Microemulsion for the treatment of dry eye syndrome
CA3178825A1 (en) 2020-06-09 2021-12-16 David Henry SNYDACKER Lithium extraction in the presence of scalants
IT202000029288A1 (it) * 2020-12-01 2022-06-01 Altergon Sa Sali di microbiocidi biguanidinici con glicosamminoglicani
CN112716886B (zh) * 2020-12-03 2022-07-08 国药集团三益药业（芜湖）有限公司 一种醋酸地塞米松乳膏及其制备方法
WO2022156371A1 (zh) * 2021-01-22 2022-07-28 成都瑞沐生物医药科技有限公司 一种眼用制剂的载体或辅料及其制备方法和应用
CN114788840A (zh) * 2021-01-25 2022-07-26 陆达斌 眼睛及视力保养液
CN112842936A (zh) * 2021-03-15 2021-05-28 傅博 一种眼部清洁液及其制备方法
WO2022226219A1 (en) 2021-04-23 2022-10-27 Lilac Solutions, Inc. Ion exchange devices for lithium extraction
EP4433053A1 (en) 2021-11-17 2024-09-25 Lenz Therapeutics Operations, Inc. Aceclidine derivatives, compositions thereof and methods of use thereof
US11648247B1 (en) 2021-12-16 2023-05-16 Lenz Therapeutics, Inc. Compositions and methods for the treatment of presbyopia
ES2944784A1 (es) * 2021-12-23 2023-06-23 Univ Madrid Complutense Microemulsión oftálmica, procedimiento de obtención y uso dado a la misma
EP4499260A1 (en) 2022-03-28 2025-02-05 Lilac Solutions, Inc. Devices for efficient sorbent utilization in lithium extraction
WO2023192623A2 (en) 2022-04-01 2023-10-05 Lilac Solutions, Inc. Extraction of lithium with chemical additives
US20240165147A1 (en) * 2022-11-21 2024-05-23 Bausch + Lomb Ireland Limited Methods for Treating Eyetear Film Deficiency
WO2025108987A1 (en) * 2023-11-21 2025-05-30 Bausch + Lomb Ireland Limited Compositions and methods for treating eyetear film deficiency and redeye

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258063A (en) * 1978-06-23 1981-03-24 Henkel Corporation Self-emulsifying cosmetic base
US4818614A (en) * 1985-07-29 1989-04-04 Shiseido Company Ltd. Modified powder
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
JPH05503527A (ja) * 1990-02-22 1993-06-10 マクノート・ピーティーワイ・リミテッド 人工涙液
ATE183099T1 (de) * 1991-04-19 1999-08-15 Lds Technologies Inc Konvertierbare mikroemulsionsverbindungen
IL101241A (en) * 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
US5858346A (en) * 1997-05-09 1999-01-12 Allergan Compositions and methods for enhancing contact lens wearability
GB2326337A (en) * 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
CA2294032A1 (en) * 1997-07-29 1999-02-11 Pharmacia & Upjohn Company Self-emulsifying formulation for lipophilic compounds
WO1999029316A1 (en) * 1997-12-10 1999-06-17 Severson, Mary, L. Pharmaceutical compositions containing an omega-3 fatty acid oil
US6979456B1 (en) * 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
FR2787027B1 (fr) * 1998-12-14 2001-01-12 Oreal Nanoemulsion a base d'esters gras de sucre ou d'ethers gras de sucre et ses utilisations dans les domaines cosmetique, dermatologique et/ou ophtalmologique
US6761903B2 (en) * 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent
US6506394B1 (en) * 1999-06-30 2003-01-14 Kimberly-Clark Worldwide, Inc. Delivery of a botanical extract to a treated substrate for transfer to skin
US6309663B1 (en) * 1999-08-17 2001-10-30 Lipocine Inc. Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents
ATE250924T1 (de) * 2000-04-07 2003-10-15 Medidom Lab Cyklosporin, hyaluronsäure und polysorbate enthaltenes augenarzneimittel
WO2001097784A1 (fr) * 2000-06-23 2001-12-27 Takeda Chemical Industries, Ltd. Procede de production de medicaments contenant des phospholipides
US7235230B2 (en) * 2001-10-24 2007-06-26 Clariant Finance (Bvi) Limited Leave-on compositions for personal care
US6656460B2 (en) * 2001-11-01 2003-12-02 Yissum Research Development Method and composition for dry eye treatment
US20030165545A1 (en) * 2002-01-30 2003-09-04 Allergan, Inc. Ophthalmic compositions including oil-in-water emulsions, and methods for making and using same
US20040137079A1 (en) * 2003-01-08 2004-07-15 Cook James N. Contact lens and eye drop rewetter compositions and methods
US20040185068A1 (en) * 2003-03-18 2004-09-23 Zhi-Jian Yu Self-emulsifying compositions, methods of use and preparation

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US20050196370A1 (en) 2005-09-08
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