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BRPI0509901A - aparelho e método para liberação transdérmica de agentes com base em fentanila - Google Patents

aparelho e método para liberação transdérmica de agentes com base em fentanila

Info

Publication number
BRPI0509901A
BRPI0509901A BRPI0509901-3A BRPI0509901A BRPI0509901A BR PI0509901 A BRPI0509901 A BR PI0509901A BR PI0509901 A BRPI0509901 A BR PI0509901A BR PI0509901 A BRPI0509901 A BR PI0509901A
Authority
BR
Brazil
Prior art keywords
fentanyl
microprojection member
based agent
based agents
contained
Prior art date
Application number
BRPI0509901-3A
Other languages
English (en)
Inventor
Mahmoud Ameri
Michel J N Cormier
Yuh-Fun Maa
Peter Daddona
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of BRPI0509901A publication Critical patent/BRPI0509901A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

APARELHO E MéTODO PARA LIBERAçãO TRANSDéRMICA DE AGENTES COM BASE EM FENTANILA. A presente invenção refere-se a um aparelho e método para transdermicamente liberar um agente biologicamente ativo compreendendo um sistema de liberação tendo um membro de microprojeção (ou sistema) que inclui uma pluralidade de microprojeções (ou conjunto destas) que são adaptadas para perfurar através do stratum corneum na camada da epiderme subjacente, ou camadas da epiderme e da derme. Em uma modalidade, o agente com base em fentanila está contido em um revestimento biocompatível que é aplicado ao membro de microprojeção. Em uma outra modalidade, o sistema de liberação inclui um pacote de gel tendo uma formulação de hidrogel contendo agente com base em fentanila que é disposta no membro de microprojeção após aplicação à pele de um paciente. Em uma modalidade alternativa, o agente com base em fentanila está contido tanto no revestimento quanto na formulação de hidrogel.
BRPI0509901-3A 2004-04-13 2005-03-18 aparelho e método para liberação transdérmica de agentes com base em fentanila BRPI0509901A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56194904P 2004-04-13 2004-04-13
PCT/US2005/009153 WO2005102334A2 (en) 2004-04-13 2005-03-18 Apparatus and method for transdermal delivery of fentany-based agents

Publications (1)

Publication Number Publication Date
BRPI0509901A true BRPI0509901A (pt) 2007-08-07

Family

ID=35197490

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0509901-3A BRPI0509901A (pt) 2004-04-13 2005-03-18 aparelho e método para liberação transdérmica de agentes com base em fentanila

Country Status (12)

Country Link
US (1) US20050226922A1 (pt)
EP (1) EP1737434A2 (pt)
JP (1) JP2007532645A (pt)
KR (1) KR20070011469A (pt)
CN (1) CN101027045A (pt)
AR (1) AR048827A1 (pt)
AU (1) AU2005235075A1 (pt)
BR (1) BRPI0509901A (pt)
CA (1) CA2562731A1 (pt)
MX (1) MXPA06011972A (pt)
TW (1) TW200602099A (pt)
WO (1) WO2005102334A2 (pt)

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EP1890732B1 (en) 2005-06-17 2018-03-28 Wisconsin Alumni Research Foundation Topical vasoconstrictor preparations and methods for protecting cells during cancer chemotherapy and radiotherapy
AU2012202731B2 (en) * 2005-06-17 2014-06-19 Wisconsin Alumni Research Foundation Topical vasoconstrictor preparations and methods for protecting cells during cancer chemotherapy and radiotherapy
AU2014202738B2 (en) * 2005-06-17 2016-05-12 Wisconsin Alumni Research Foundation Topical vasoconstrictor preparations and methods for protecting cells during cancer chemotherapy and radiotherapy
JP2009519018A (ja) * 2005-12-14 2009-05-14 アリアナ ホールディングス ピーティーワイ エルティーディー 化学薬品アプリケータ
WO2007127815A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
US10512644B2 (en) 2007-03-12 2019-12-24 Inheris Pharmaceuticals, Inc. Oligomer-opioid agonist conjugates
US8173666B2 (en) 2007-03-12 2012-05-08 Nektar Therapeutics Oligomer-opioid agonist conjugates
HUP0700828A2 (en) * 2007-12-20 2010-01-28 Richter Gedeon Nyrt Transdermal pharmaceutical compositions containing tolperisone alone and in combination
MX347741B (es) * 2008-09-16 2017-05-10 Nektar Therapeutics Opioides pegilados con bajo potencial de abuso.
US8894630B2 (en) 2009-11-13 2014-11-25 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
US8439896B2 (en) * 2009-11-13 2013-05-14 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
US8784368B2 (en) * 2009-11-13 2014-07-22 The Invention Science Fund I, Llc Device, system, and method for targeted delivery of anti-inflammatory medicaments to a mammalian subject
DK2533049T3 (en) 2010-02-05 2015-10-26 Nichirei Biosciences Inc PREPARATION SOLUTION FOR immunohistochemical staining AND CONCENTRATED SOLUTION THEREOF
CN105815785A (zh) * 2016-03-31 2016-08-03 常州大学 一种从黄瓜中提取丙醇二酸制备除脂粉的方法
US9650338B1 (en) 2016-07-29 2017-05-16 VDM Biochemicals, Inc. Opioid antagonist compounds and methods of making and using
EP3612495B1 (en) 2017-04-18 2022-07-13 Breakthrough Technologies, LLC Sulfur production
WO2019115815A1 (de) * 2017-12-14 2019-06-20 Lts Lohmann Therapie-Systeme Ag Mikronadelarray aufweisend einen wirkstoff in form von salzen
CN108318646A (zh) * 2018-03-27 2018-07-24 苏州桓晨医疗科技有限公司 一种模拟药物体外释放的释放介质
WO2021216925A1 (en) * 2020-04-22 2021-10-28 Zosano Pharma Corporation Transdermal active agent delivery devices having coronavirus vaccine coated microprotrusions

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US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
US4486423A (en) * 1983-04-21 1984-12-04 Janssen Pharmaceutica Inc. Stable fentanyl composition
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US5169382A (en) * 1988-10-03 1992-12-08 Alza Corporation Membrane for electrotransport transdermal drug delivery
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AU5740496A (en) * 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
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ATE221400T1 (de) * 1997-12-11 2002-08-15 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
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JP4205778B2 (ja) * 1998-04-17 2009-01-07 久光製薬株式会社 貼付製剤
ATE302598T1 (de) * 1999-04-01 2005-09-15 Alza Corp Transdermale vorrichtung zur arzneistoffverabreichung mit einem polyurethanwirkstoffreservoir
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Also Published As

Publication number Publication date
WO2005102334A2 (en) 2005-11-03
TW200602099A (en) 2006-01-16
KR20070011469A (ko) 2007-01-24
EP1737434A2 (en) 2007-01-03
JP2007532645A (ja) 2007-11-15
CN101027045A (zh) 2007-08-29
WO2005102334A3 (en) 2006-02-09
MXPA06011972A (es) 2007-04-16
CA2562731A1 (en) 2005-11-03
US20050226922A1 (en) 2005-10-13
AU2005235075A1 (en) 2005-11-03
AR048827A1 (es) 2006-05-31

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]