BRPI0416736A - construções de ácidos nucleicos, proteìnas imunogênicas isoladas, cepas de leishmania geneticamente modificadas, e, processo de transfecção de um parasita de leishmania - Google Patents
construções de ácidos nucleicos, proteìnas imunogênicas isoladas, cepas de leishmania geneticamente modificadas, e, processo de transfecção de um parasita de leishmaniaInfo
- Publication number
- BRPI0416736A BRPI0416736A BRPI0416736-8A BRPI0416736A BRPI0416736A BR PI0416736 A BRPI0416736 A BR PI0416736A BR PI0416736 A BRPI0416736 A BR PI0416736A BR PI0416736 A BRPI0416736 A BR PI0416736A
- Authority
- BR
- Brazil
- Prior art keywords
- seq
- leishmania
- nucleic acid
- transfecting
- genetically modified
- Prior art date
Links
- 241000222722 Leishmania <genus> Species 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 230000002163 immunogen Effects 0.000 title abstract 2
- 244000045947 parasite Species 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 230000029142 excretion Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 230000002018 overexpression Effects 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/008—Leishmania antigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/473—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used alpha-Glycoproteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Abstract
"CONSTRUçõES DE áCIDOS NUCLEICOS, PROTEìNAS IMUNOGêNICAS ISOLADAS, CEPAS DE LEISHMANIA GENETICAMENTE MODIFICADAS, E, PROCESSO DE TRANSFECçãO DE UM PARASITA DE LEISHMANIA". A invenção tem por objeto construções de ácidos nucleicos, caracterizadas em que elas comportam ácidos nucleicos isolados em posição sentido, capazes de codificar para uma proteína imunogênica de formas de promastigotos ou de formas de amastigotos de Leishimania, os referidos ácidos nucleicos respondendo a uma das seqüências SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5 e SEQ ID NO: 11, e codificando para uma proteína apresentando, respectivamente, uma seqüência SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 10 e SEQ ID NO: 12. Aplicação para a super-expressão de genes de Leishmania codificando para um antígeno de excreção/ secreção.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0313555A FR2862313B1 (fr) | 2003-11-19 | 2003-11-19 | Nouveaux moyens pour la prevention des leishmanioses |
| FR0313555 | 2003-11-19 | ||
| FR0407010 | 2004-06-25 | ||
| FR0407010A FR2863272B1 (fr) | 2003-11-19 | 2004-06-25 | Nouveaux moyens pour la prevention des leishmanioses |
| PCT/FR2004/002955 WO2005051989A2 (fr) | 2003-11-19 | 2004-11-19 | Nouveaux moyens pour la prévention des leishmanioses |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BRPI0416736A true BRPI0416736A (pt) | 2007-01-16 |
| BRPI0416736B1 BRPI0416736B1 (pt) | 2019-05-21 |
| BRPI0416736B8 BRPI0416736B8 (pt) | 2021-05-25 |
Family
ID=34593697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0416736A BRPI0416736B8 (pt) | 2003-11-19 | 2004-11-19 | construções de ácidos nucleicos, proteínas imunogênicas isoladas, cepas de leishmania geneticamente modificadas, e, processo de transfecção de um parasita de leishmania |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8574598B2 (pt) |
| EP (1) | EP1685156B1 (pt) |
| AT (1) | ATE463507T1 (pt) |
| AU (1) | AU2004293211B2 (pt) |
| BR (1) | BRPI0416736B8 (pt) |
| CA (1) | CA2546326C (pt) |
| DE (1) | DE602004026466D1 (pt) |
| ES (1) | ES2345824T3 (pt) |
| FR (1) | FR2863272B1 (pt) |
| PT (1) | PT1685156E (pt) |
| WO (1) | WO2005051989A2 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2863272B1 (fr) | 2003-11-19 | 2006-06-09 | Inst Rech Developpement Ird | Nouveaux moyens pour la prevention des leishmanioses |
| FR2881752B1 (fr) * | 2005-02-10 | 2009-07-31 | Inst Rech Pour Le Dev I R D Et | Moyens pour l'obtention de promastigotes de leishmanies avirulents, promastigotes obtenus et leurs applications |
| FR2932802B1 (fr) * | 2008-06-19 | 2010-08-20 | Oridan Inc | Peptide de synthese non natif cyclise et complexe de peptides comprenant ledit peptide cyclise, destine a induire et a caracteriser la prevention ou le traitement d'affections chez les mammiferes |
| FR2960550A1 (fr) | 2010-05-26 | 2011-12-02 | Inst Rech R Pour Le Dev Ird | Moyens pour la production transitoire dans les plantes de proteines recombinantes utilisables notamment en prophylaxie et en therapeutique |
| FR3014103B1 (fr) * | 2013-11-29 | 2019-08-16 | Institut De Recherche Pour Le Developpement (Ird) | Composition vaccinale pour la prevention et/ou le traitement de leishmanioses, peptides immunogenes et procede d'obtention |
| WO2021127271A1 (en) * | 2019-12-17 | 2021-06-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Live attenuated leishmania parasite vaccines with enhanced safety characteristics |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2705358B1 (fr) * | 1993-05-13 | 1995-08-04 | Orstom | Procédé de culture in vitro de différents stades de parasites tissulaires, stades parasitaires obtenus et applications biologiques. |
| US20020169285A1 (en) * | 1995-09-22 | 2002-11-14 | Reed Steven G. | Leishmania antigens for use in the therapy and diagnosis of leishmaniasis |
| ES2169995B1 (es) * | 2000-04-17 | 2003-12-01 | Leti Lab | Composicion a base de la proteina lip2a y su uso en la preparacion de un medicamento para suscitar una respuesta inmune contra un antigeno. |
| FR2863272B1 (fr) | 2003-11-19 | 2006-06-09 | Inst Rech Developpement Ird | Nouveaux moyens pour la prevention des leishmanioses |
| FR2881752B1 (fr) | 2005-02-10 | 2009-07-31 | Inst Rech Pour Le Dev I R D Et | Moyens pour l'obtention de promastigotes de leishmanies avirulents, promastigotes obtenus et leurs applications |
-
2004
- 2004-06-25 FR FR0407010A patent/FR2863272B1/fr not_active Expired - Fee Related
- 2004-11-19 WO PCT/FR2004/002955 patent/WO2005051989A2/fr active Application Filing
- 2004-11-19 ES ES04805492T patent/ES2345824T3/es not_active Expired - Lifetime
- 2004-11-19 CA CA2546326A patent/CA2546326C/fr not_active Expired - Fee Related
- 2004-11-19 AT AT04805492T patent/ATE463507T1/de not_active IP Right Cessation
- 2004-11-19 DE DE602004026466T patent/DE602004026466D1/de not_active Expired - Lifetime
- 2004-11-19 US US10/579,749 patent/US8574598B2/en not_active Expired - Fee Related
- 2004-11-19 PT PT04805492T patent/PT1685156E/pt unknown
- 2004-11-19 BR BRPI0416736A patent/BRPI0416736B8/pt not_active IP Right Cessation
- 2004-11-19 AU AU2004293211A patent/AU2004293211B2/en not_active Ceased
- 2004-11-19 EP EP04805492A patent/EP1685156B1/fr not_active Expired - Lifetime
-
2013
- 2013-11-04 US US14/070,685 patent/US20140193452A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1685156A2 (fr) | 2006-08-02 |
| AU2004293211A1 (en) | 2005-06-09 |
| CA2546326C (fr) | 2013-08-27 |
| ATE463507T1 (de) | 2010-04-15 |
| WO2005051989A2 (fr) | 2005-06-09 |
| DE602004026466D1 (de) | 2010-05-20 |
| FR2863272A1 (fr) | 2005-06-10 |
| ES2345824T3 (es) | 2010-10-04 |
| US20140193452A1 (en) | 2014-07-10 |
| US20080026467A1 (en) | 2008-01-31 |
| BRPI0416736B8 (pt) | 2021-05-25 |
| WO2005051989A3 (fr) | 2005-09-29 |
| US8574598B2 (en) | 2013-11-05 |
| BRPI0416736B1 (pt) | 2019-05-21 |
| FR2863272B1 (fr) | 2006-06-09 |
| AU2004293211B2 (en) | 2011-04-21 |
| EP1685156B1 (fr) | 2010-04-07 |
| CA2546326A1 (fr) | 2005-06-09 |
| PT1685156E (pt) | 2010-05-31 |
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Legal Events
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| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 21/05/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 21/05/2019, OBSERVADAS AS CONDICOES LEGAIS |
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| B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/11/2004 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
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| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 18A ANUIDADE. |
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| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2697 DE 13-09-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |