BR9912587A - Processo sistema e dispositivo para realçar a absorção celular de uma substância, processos para realçar a transfecção de gene de um gene transferido para uma região alvo do corpo de um paciente e para promover a angiogênese em membros isquêmicos, e, kit - Google Patents
Processo sistema e dispositivo para realçar a absorção celular de uma substância, processos para realçar a transfecção de gene de um gene transferido para uma região alvo do corpo de um paciente e para promover a angiogênese em membros isquêmicos, e, kitInfo
- Publication number
- BR9912587A BR9912587A BR9912587-0A BR9912587A BR9912587A BR 9912587 A BR9912587 A BR 9912587A BR 9912587 A BR9912587 A BR 9912587A BR 9912587 A BR9912587 A BR 9912587A
- Authority
- BR
- Brazil
- Prior art keywords
- enhancing
- target region
- substance
- patient
- gene
- Prior art date
Links
- 230000002708 enhancing effect Effects 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- 238000010521 absorption reaction Methods 0.000 title abstract 4
- 239000000126 substance Substances 0.000 title abstract 4
- 230000001413 cellular effect Effects 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 230000033115 angiogenesis Effects 0.000 title abstract 2
- 230000000302 ischemic effect Effects 0.000 title abstract 2
- 238000012637 gene transfection Methods 0.000 title 1
- 238000001890 transfection Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Abstract
"PROCESSO. SISTEMA E DISPOSITIVO PARA REALçAR A ABSORçãO CELULAR DE UMA SUBSTâNCIA, PROCESSOS PARA REALçAR A TRANSFECçãO DE GENE DE UM GENE TRANSFERIDO PARA UMA REGIãO ALVO DO CORPO DE UM PACIENTE E PARA PROMOVER A ANGIOGêNESE EM MEMBROS ISQUêMICOS E, KIT". A invenção é um processo de realçar a absorção celular de uma substância liberada em uma região alvo do corpo de um paciente, que compreende transferir a substância ( 21 ) para a região alvo ( 22 ) e direcionar energia vibracional ( 32 ) para a região alvo, em que a energia vibracional é de um tipo e em uma quantidade suficiente para realçar a absorção nas células ( 24 ) da região alvo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/126,011 US6464680B1 (en) | 1998-07-29 | 1998-07-29 | Ultrasonic enhancement of drug injection |
US25529099A | 1999-02-22 | 1999-02-22 | |
PCT/US1999/017305 WO2000006032A1 (en) | 1998-07-29 | 1999-07-29 | Ultrasonic enhancement of drug injection |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9912587A true BR9912587A (pt) | 2002-06-11 |
Family
ID=26824191
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9912587-0A BR9912587A (pt) | 1998-07-29 | 1999-07-29 | Processo sistema e dispositivo para realçar a absorção celular de uma substância, processos para realçar a transfecção de gene de um gene transferido para uma região alvo do corpo de um paciente e para promover a angiogênese em membros isquêmicos, e, kit |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1107702A4 (pt) |
JP (1) | JP2002521118A (pt) |
AU (1) | AU754022B2 (pt) |
BR (1) | BR9912587A (pt) |
CA (1) | CA2338396A1 (pt) |
WO (1) | WO2000006032A1 (pt) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
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US6050943A (en) | 1997-10-14 | 2000-04-18 | Guided Therapy Systems, Inc. | Imaging, therapy, and temperature monitoring ultrasonic system |
AU3597100A (en) * | 1999-02-22 | 2000-09-04 | Pharmasonics, Inc. | Methods and apparatus for uniform transcutaneous therapeutic ultrasound |
US7914453B2 (en) | 2000-12-28 | 2011-03-29 | Ardent Sound, Inc. | Visual imaging system for ultrasonic probe |
US6623444B2 (en) * | 2001-03-21 | 2003-09-23 | Advanced Medical Applications, Inc. | Ultrasonic catheter drug delivery method and device |
US20030147812A1 (en) * | 2001-12-11 | 2003-08-07 | Friedrich Ueberle | Device and methods for initiating chemical reactions and for the targeted delivery of drugs or other agents |
US7358226B2 (en) * | 2003-08-27 | 2008-04-15 | The Regents Of The University Of California | Ultrasonic concentration of drug delivery capsules |
US9011336B2 (en) | 2004-09-16 | 2015-04-21 | Guided Therapy Systems, Llc | Method and system for combined energy therapy profile |
US7824348B2 (en) | 2004-09-16 | 2010-11-02 | Guided Therapy Systems, L.L.C. | System and method for variable depth ultrasound treatment |
US7393325B2 (en) | 2004-09-16 | 2008-07-01 | Guided Therapy Systems, L.L.C. | Method and system for ultrasound treatment with a multi-directional transducer |
US8444562B2 (en) | 2004-10-06 | 2013-05-21 | Guided Therapy Systems, Llc | System and method for treating muscle, tendon, ligament and cartilage tissue |
US10864385B2 (en) | 2004-09-24 | 2020-12-15 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
US8535228B2 (en) | 2004-10-06 | 2013-09-17 | Guided Therapy Systems, Llc | Method and system for noninvasive face lifts and deep tissue tightening |
US8133180B2 (en) | 2004-10-06 | 2012-03-13 | Guided Therapy Systems, L.L.C. | Method and system for treating cellulite |
US11883688B2 (en) | 2004-10-06 | 2024-01-30 | Guided Therapy Systems, Llc | Energy based fat reduction |
US9694212B2 (en) | 2004-10-06 | 2017-07-04 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of skin |
US7758524B2 (en) | 2004-10-06 | 2010-07-20 | Guided Therapy Systems, L.L.C. | Method and system for ultra-high frequency ultrasound treatment |
US20060111744A1 (en) | 2004-10-13 | 2006-05-25 | Guided Therapy Systems, L.L.C. | Method and system for treatment of sweat glands |
DE202005022028U1 (de) | 2004-10-06 | 2012-07-09 | Guided Therapy Systems, Llc | System zur Ultraschallgewebebehandlung |
US9827449B2 (en) | 2004-10-06 | 2017-11-28 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
US8690779B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Noninvasive aesthetic treatment for tightening tissue |
JP2008522642A (ja) | 2004-10-06 | 2008-07-03 | ガイデッド セラピー システムズ, エル.エル.シー. | 美容強化のための方法およびシステム |
US11235179B2 (en) | 2004-10-06 | 2022-02-01 | Guided Therapy Systems, Llc | Energy based skin gland treatment |
US11724133B2 (en) | 2004-10-07 | 2023-08-15 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
US11207548B2 (en) | 2004-10-07 | 2021-12-28 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
US7571336B2 (en) | 2005-04-25 | 2009-08-04 | Guided Therapy Systems, L.L.C. | Method and system for enhancing safety with medical peripheral device by monitoring if host computer is AC powered |
US20070232986A1 (en) * | 2006-03-31 | 2007-10-04 | Cytodome, Inc. | Low-profile implantable ultrasound array and method for enhancing drug delivery to tissue |
US9566454B2 (en) | 2006-09-18 | 2017-02-14 | Guided Therapy Systems, Llc | Method and sysem for non-ablative acne treatment and prevention |
US20150174388A1 (en) | 2007-05-07 | 2015-06-25 | Guided Therapy Systems, Llc | Methods and Systems for Ultrasound Assisted Delivery of a Medicant to Tissue |
US9216276B2 (en) | 2007-05-07 | 2015-12-22 | Guided Therapy Systems, Llc | Methods and systems for modulating medicants using acoustic energy |
US12102473B2 (en) | 2008-06-06 | 2024-10-01 | Ulthera, Inc. | Systems for ultrasound treatment |
ES2571680T3 (es) | 2008-06-06 | 2016-05-26 | Ulthera Inc | Sistema para tratamiento cosmético y formación de imágenes |
JP2012513837A (ja) | 2008-12-24 | 2012-06-21 | ガイデッド セラピー システムズ, エルエルシー | 脂肪減少および/またはセルライト処置のための方法およびシステム |
US8715186B2 (en) | 2009-11-24 | 2014-05-06 | Guided Therapy Systems, Llc | Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy |
US10183182B2 (en) | 2010-08-02 | 2019-01-22 | Guided Therapy Systems, Llc | Methods and systems for treating plantar fascia |
US9504446B2 (en) | 2010-08-02 | 2016-11-29 | Guided Therapy Systems, Llc | Systems and methods for coupling an ultrasound source to tissue |
US8857438B2 (en) | 2010-11-08 | 2014-10-14 | Ulthera, Inc. | Devices and methods for acoustic shielding |
WO2013009785A2 (en) | 2011-07-10 | 2013-01-17 | Guided Therapy Systems, Llc. | Systems and methods for improving an outside appearance of skin using ultrasound as an energy source |
KR20140047709A (ko) | 2011-07-11 | 2014-04-22 | 가이디드 테라피 시스템스, 엘.엘.씨. | 조직에 초음파원을 연결하는 시스템 및 방법 |
US9263663B2 (en) | 2012-04-13 | 2016-02-16 | Ardent Sound, Inc. | Method of making thick film transducer arrays |
US9510802B2 (en) | 2012-09-21 | 2016-12-06 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
CN113648551B (zh) | 2013-03-08 | 2025-03-25 | 奥赛拉公司 | 用于多焦点超声治疗的装置和方法 |
US10561862B2 (en) | 2013-03-15 | 2020-02-18 | Guided Therapy Systems, Llc | Ultrasound treatment device and methods of use |
CA2944707C (en) | 2014-04-18 | 2023-01-24 | Ulthera, Inc. | Band transducer ultrasound therapy |
RU2720661C2 (ru) | 2016-01-18 | 2020-05-12 | Ультера, Инк. | Компактное ультразвуковое устройство, содержащее кольцеобразную ультразвуковую матрицу, электрически соединенную по периферии с гибкой печатной платой, и способ сборки такого устройства |
KR20230149878A (ko) | 2016-08-16 | 2023-10-27 | 얼테라, 인크 | 이미징 오정렬을 감소시키도록 구성된 초음파 이미징 시스템, 초음파 이미징 모듈 및 이미징 오정렬을 감소시키는 방법 |
TW202327520A (zh) | 2018-01-26 | 2023-07-16 | 美商奧賽拉公司 | 用於多個維度中的同時多聚焦超音治療的系統和方法 |
US11944849B2 (en) | 2018-02-20 | 2024-04-02 | Ulthera, Inc. | Systems and methods for combined cosmetic treatment of cellulite with ultrasound |
JP7598331B2 (ja) | 2019-11-18 | 2024-12-11 | 株式会社カネカ | 薬液拡散システムおよび薬液拡散促進装置 |
CN112023243B (zh) * | 2020-09-15 | 2022-03-25 | 南京大学 | 超声循环聚焦发射的透皮给药装置及控制方法 |
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US5016615A (en) * | 1990-02-20 | 1991-05-21 | Riverside Research Institute | Local application of medication with ultrasound |
US5197946A (en) * | 1990-06-27 | 1993-03-30 | Shunro Tachibana | Injection instrument with ultrasonic oscillating element |
US5386837A (en) * | 1993-02-01 | 1995-02-07 | Mmtc, Inc. | Method for enhancing delivery of chemotherapy employing high-frequency force fields |
US5667487A (en) * | 1993-04-07 | 1997-09-16 | Henley; Julian L. | Ionosonic drug delivery apparatus |
US5490840A (en) * | 1994-09-26 | 1996-02-13 | General Electric Company | Targeted thermal release of drug-polymer conjugates |
US5752515A (en) * | 1996-08-21 | 1998-05-19 | Brigham & Women's Hospital | Methods and apparatus for image-guided ultrasound delivery of compounds through the blood-brain barrier |
WO1998018391A1 (en) * | 1996-10-30 | 1998-05-07 | Ekos Corporation | Intraluminal wall drug delivery device |
-
1999
- 1999-07-29 BR BR9912587-0A patent/BR9912587A/pt not_active IP Right Cessation
- 1999-07-29 JP JP2000561891A patent/JP2002521118A/ja not_active Withdrawn
- 1999-07-29 CA CA002338396A patent/CA2338396A1/en not_active Abandoned
- 1999-07-29 WO PCT/US1999/017305 patent/WO2000006032A1/en not_active Application Discontinuation
- 1999-07-29 EP EP99937661A patent/EP1107702A4/en not_active Withdrawn
- 1999-07-29 AU AU52450/99A patent/AU754022B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU754022B2 (en) | 2002-10-31 |
AU5245099A (en) | 2000-02-21 |
JP2002521118A (ja) | 2002-07-16 |
CA2338396A1 (en) | 2000-02-10 |
EP1107702A1 (en) | 2001-06-20 |
WO2000006032A1 (en) | 2000-02-10 |
EP1107702A4 (en) | 2002-10-09 |
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