[go: up one dir, main page]

BR9905089A - Derivados macrolìdeos - Google Patents

Derivados macrolìdeos

Info

Publication number
BR9905089A
BR9905089A BR9905089-7A BR9905089A BR9905089A BR 9905089 A BR9905089 A BR 9905089A BR 9905089 A BR9905089 A BR 9905089A BR 9905089 A BR9905089 A BR 9905089A
Authority
BR
Brazil
Prior art keywords
compounds
formula
macrolide derivatives
derivatives
macrolydic
Prior art date
Application number
BR9905089-7A
Other languages
English (en)
Inventor
Brian Scott Bronk
Hengmiao Cheng
Jason Kenneth Dutra
Michael Anthony Letavic
Robert John Rafka
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR9905089A publication Critical patent/BR9905089A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Patente de Invenção: <B>"DERIVADOS MACROLìDEOS"<D>. A invenção refere-se a compostos da fórmula I e aos seus sais farmaceuticamente aceitáveis, em que R^ 1^, R^ 2^, R^ 3^, Q, X, Y, e Z têm o significado atribuído no texto. A invenção também abarca composições farmacêuticas contendo os compostos da fórmula I, os métodos de utilização dos referidos compostos da fórmula I para tratamento de infecções, e os processos de síntese dos referidos compostos da fórmula I.
BR9905089-7A 1998-10-09 1999-10-11 Derivados macrolìdeos BR9905089A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10383898P 1998-10-09 1998-10-09

Publications (1)

Publication Number Publication Date
BR9905089A true BR9905089A (pt) 2000-08-08

Family

ID=22297279

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9905089-7A BR9905089A (pt) 1998-10-09 1999-10-11 Derivados macrolìdeos

Country Status (10)

Country Link
US (1) US6100240A (pt)
EP (1) EP0992509B1 (pt)
JP (1) JP3679656B2 (pt)
AT (1) ATE277062T1 (pt)
BR (1) BR9905089A (pt)
CA (1) CA2286511C (pt)
DE (1) DE69920362T2 (pt)
DK (1) DK0992509T3 (pt)
ES (1) ES2226294T3 (pt)
PT (1) PT992509E (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001515865A (ja) * 1997-09-10 2001-09-25 メルク エンド カムパニー インコーポレーテッド 家畜抗菌剤としての９ａ−アザライド
US6339063B1 (en) 1997-09-10 2002-01-15 Merck & Co., Inc. 9a-azalides as veterinary antimicrobial agents
EP1779853A3 (en) * 1997-09-10 2010-01-27 Merial Ltd. 9a-azalides as veterinary antimicrobial agents
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
IL144178A0 (en) * 1999-01-27 2002-05-23 Pfizer Prod Inc Ketolide antibiotics
CA2292359C (en) * 1999-01-28 2004-09-28 Pfizer Products Inc. Novel azalides and methods of making same
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
CZ20013733A3 (cs) * 1999-05-24 2002-11-13 Pfizer Products Inc. Deriváty 13-methylerythromycinu
US6420535B1 (en) * 1999-06-07 2002-07-16 Abbott Laboratories 6-O-carbamate ketolide derivatives
SK14882002A3 (en) * 2000-04-27 2004-11-03 Pfizer Prod Inc The use of azalide antibiotic compositions for treating or preventing a bacterial or protozoal infection in mammals
EP1471923A4 (en) * 2002-01-17 2006-01-11 Kosan Biosciences Inc AMIDO macrolides
WO2003070173A2 (en) 2002-02-15 2003-08-28 Sympore Gmbh Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
AU2003211113B2 (en) 2002-02-15 2007-08-09 Merckle Gmbh Antibiotic conjugates
US20050171342A1 (en) 2002-02-15 2005-08-04 Michael Burnet Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
CN101423539B (zh) * 2008-12-09 2011-04-27 山东大学 4″,11-二氨基甲酸酯阿奇霉素衍生物、制备方法及其药物组合物
CN103965273B (zh) * 2013-08-23 2016-05-25 普莱柯生物工程股份有限公司 一种大环内酯类化合物
CN105669798B (zh) * 2013-08-23 2019-07-26 普莱柯生物工程股份有限公司 一种大环内酯类化合物
CN109535211B (zh) * 2018-12-19 2020-05-08 江苏威凌生化科技有限公司 一种合成纯化泰拉霉素杂质c的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5441939A (en) * 1994-03-04 1995-08-15 Pfizer Inc. 3"-desmethoxy derivatives of erythromycin and azithromycin
US5641753A (en) * 1996-03-25 1997-06-24 Chris E. Platt 10-AZA-9-deoxo-11-deoxy-erythromycin A and derivatives combined with sulfisoxazole
HN1998000074A (es) * 1997-06-11 1999-01-08 Pfizer Prod Inc Derivados de macrolidos c-4 sustituidos
HN1998000086A (es) * 1997-06-11 1999-03-08 Pfizer Prod Inc Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.

Also Published As

Publication number Publication date
EP0992509A3 (en) 2001-03-07
PT992509E (pt) 2004-12-31
ATE277062T1 (de) 2004-10-15
JP3679656B2 (ja) 2005-08-03
EP0992509A2 (en) 2000-04-12
CA2286511A1 (en) 2000-04-09
DK0992509T3 (da) 2004-12-20
EP0992509B1 (en) 2004-09-22
DE69920362D1 (de) 2004-10-28
DE69920362T2 (de) 2006-02-09
CA2286511C (en) 2003-07-08
ES2226294T3 (es) 2005-03-16
US6100240A (en) 2000-08-08
JP2000119294A (ja) 2000-04-25

Similar Documents

Publication Publication Date Title
BR9905089A (pt) Derivados macrolìdeos
BRPI9810519A (pt) derivados de 4&#39;&#39;-substituído-9-desoxo-9a-aza-9a-homoeritromicina a e composição farmacêutica compreendendo os mesmos.
BR0010938A (pt) Derivados da 13-metil eritromicina
BR0111263A (pt) Derivados de 2-aminocarbonil-9h-purina
BR9810097A (pt) Derivados de macrolìdeos c-4-substituìdos
BR0012590A (pt) Composto, processo para a preparação do mesmo, formulação farmacêutica, uso de um composto, e, métodos para tratamento ou profilaxia de dor ou desconforto, e para tratamento ou profilaxia de dor neuropática ou central
BR9810021A (pt) Derivados 9-oxima-eritromicina
MY133473A (en) Haterocyclic glycyl beta-alanine derivatives.
BR0215240A (pt) Derivados de calcona e seu uso no tratamento de doenças
BR0010746A (pt) Derivados heterocìclicos úteis com agentes anticâncer
BR0111377A (pt) Derivados de tiofeno úteis como agentes anticancerìgenos
BR0211289A (pt) Derivados de dolastatina 10
ES2160949T3 (es) Derivados de fenilen-sulfonamida sustituidos en meta.
BR0215312A (pt) Uso de um composto, método para inibir a aurora quinase em um animal de sangue quente, composto, composição farmacêutica, e, processo para a preparação de um composto
BR0000003A (pt) Azalidas e métodos de preparação das mesmas
AP9801378A0 (en) 9-amino-3- keto erythromycin derivatives.
DK0889877T3 (da) Meta-substituerede phenylenderivater og deres anvendelse som alfav-beta3-integrin-antagonister eller -inhibitorer
BR9814601A (pt) &#34;macrólidos&#34;
BR9911160A (pt) Ciclosporinas
BR9915480A (pt) Azalìdeos de 13 membros e a sua utilização como agentes antibióticos
BR0212069A (pt) Agentes antidiabéticos orais
BR9813319A (pt) Composto, composição farmacêutica para tratamento de infecções bacterianas, e, processos para tratar infecções bacterianas e para preparar um composto
BR0008297A (pt) Uso de 4,6-o-(benzilideno-d1) -d-glucopiranose, 4,6-o-benzilideno-l-glucopiranose, e/ou 4,6-o-(benzilideno-d1) -l-glucopiranose, ou um sal farmacêutico aceitável dos mesmos, derivado de benzaldeìdo composição farmacêutica, e, processo para a fabricação da mesma
BR9705456A (pt) Compostos heterocìclicos, processo de aminometila para sua preparação e composições farmacêuticas que os contêm.
BR0015333A (pt) Derivados de isoxazol como inibidores de fosfodiesterase vii

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 8O DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.