BR9807537B1 - composição liofilizada de fator humano morfogenético ósseo mp52, bem como processo para sua preparação. - Google Patents

composição liofilizada de fator humano morfogenético ósseo mp52, bem como processo para sua preparação.

Info

Publication number: BR9807537B1
Authority: BR; Brazil
Prior art keywords: preparation; well; bone morphogenetic; human bone; lyophilized composition
Prior art date: 1997-01-30

Application number

BRPI9807537-3A

Other languages

English (en)

Other versions

BR9807537A (pt

Inventor

Hideki Ichikawa

Mitsuko Inagaki

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-01-30

Filing date

1998-01-29

Publication date

2009-01-13

1998-01-29 Application filed filed Critical

2000-03-21 Publication of BR9807537A publication Critical patent/BR9807537A/pt

2009-01-13 Publication of BR9807537B1 publication Critical patent/BR9807537B1/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Immunology (AREA)
Zoology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

BRPI9807537-3A 1997-01-30 1998-01-29 composição liofilizada de fator humano morfogenético ósseo mp52, bem como processo para sua preparação. BR9807537B1 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP1634997		1997-01-30
PCT/JP1998/000371 WO1998033514A1 (fr)	1997-01-30	1998-01-29	Composition lyophilisee de mp52 humaine de proteines morphogenetiques osseuses

Publications (2)

Publication Number	Publication Date
BR9807537A BR9807537A (pt)	2000-03-21
BR9807537B1 true BR9807537B1 (pt)	2009-01-13

Family

ID=11913900

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI9807537-3A BR9807537B1 (pt)	1997-01-30	1998-01-29	composição liofilizada de fator humano morfogenético ósseo mp52, bem como processo para sua preparação.

Country Status (22)

Country	Link
EP (1)	EP0972520B9 (pt)
JP (1)	JP4209948B2 (pt)
KR (1)	KR100548107B1 (pt)
CN (1)	CN1152712C (pt)
AP (1)	AP983A (pt)
AT (1)	ATE302021T1 (pt)
AU (1)	AU737595B2 (pt)
BR (1)	BR9807537B1 (pt)
CA (1)	CA2278546C (pt)
DE (1)	DE69831223T9 (pt)
DK (1)	DK0972520T3 (pt)
EA (1)	EA001579B1 (pt)
ES (1)	ES2244043T3 (pt)
HU (1)	HU226554B1 (pt)
IL (2)	IL130967A0 (pt)
NO (1)	NO322334B1 (pt)
NZ (1)	NZ336509A (pt)
PL (1)	PL189381B1 (pt)
RS (1)	RS49691B (pt)
SI (1)	SI0972520T1 (pt)
TR (1)	TR199901832T2 (pt)
WO (1)	WO1998033514A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU6267798A (en) †	1997-02-07	1998-08-26	Stryker Corporation	Matrix-free osteogenic devices, implants and methods of use thereof
US20050053596A1 (en) *	2001-10-09	2005-03-10	Stringer Bradley Michael John	Therapeutic biological product and method for formation of new vascularised bone
ATE303169T1 (de)	2001-11-19	2005-09-15	Scil Technology Gmbh	Homogen beschichtete vorrichtung mit osteoinduktiven und osteokonduktiven eigenschaften
ATE322916T1 (de)	2002-09-10	2006-04-15	Scil Technology Gmbh	Unter verringerter sauerstoffkonzentration mit einem osteoinduktiven protein beschichtetes metallimplantat
EP1651272A1 (en) *	2003-08-05	2006-05-03	Fuji Photo Film B.V.	Use of recombinant or synthetic gelatin as a stabiliser in vaccines
EP1685160A1 (en) *	2003-11-10	2006-08-02	Arriva-Prometic Inc.	Dry recombinant human alpha 1-antitrypsin formulation
DE602005022998D1 (de)	2004-03-10	2010-09-30	Scil Technology Gmbh	Überzogene implantate, ihre herstellung und verwendung davon
US10360287B2 (en)	2015-05-22	2019-07-23	Microsoft Technology Licensing, Llc	Unified messaging platform and interface for providing user callouts
US20160344677A1 (en)	2015-05-22	2016-11-24	Microsoft Technology Licensing, Llc	Unified messaging platform for providing interactive semantic objects

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0080879B1 (en) *	1981-11-28	1986-10-01	Sunstar Kabushiki Kaisha	Pharmaceutical composition containing interferon in stable state
US5037644A (en) *	1986-10-27	1991-08-06	Cetus Corporation	Pharmaceutical compositions of recombinant interleukin-2 and formulation processes
AU663328B2 (en) *	1991-06-21	1995-10-05	Genetics Institute, Llc	Pharmaceutical formulations of osteogenic proteins
JP2966592B2 (ja) *	1991-07-20	1999-10-25	萩原義秀	安定化されたヒトモノクローナル抗体製剤
KR0172186B1 (ko) *	1992-02-12	1999-02-01	미하엘 파울리스타	신규의 성장/분화인자를 암호화하는 dna 서열
CA2093836A1 (en) *	1992-04-24	1993-10-25	Wayne Gombotz	Biodegradable tgf-.beta. delivery system for bone regeneration
DE4239877C1 (de) *	1992-11-27	1994-03-17	Boehringer Ingelheim Int	Stabilisierte Superoxid-Dismutase (SOD)-Zusammensetzung
DE69524456T2 (de) *	1995-03-21	2002-08-01	Applied Research Systems	Flüssige hcg-formulierungen
AU704515C (en) *	1995-04-19	2002-03-28	Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh	Novel protein and process for producing the same

1998
- 1998-01-29 DK DK98901044T patent/DK0972520T3/da active
- 1998-01-29 EA EA199900694A patent/EA001579B1/ru not_active IP Right Cessation
- 1998-01-29 AT AT98901044T patent/ATE302021T1/de active
- 1998-01-29 CN CNB988019841A patent/CN1152712C/zh not_active Expired - Fee Related
- 1998-01-29 CA CA002278546A patent/CA2278546C/en not_active Expired - Fee Related
- 1998-01-29 EP EP98901044A patent/EP0972520B9/en not_active Expired - Lifetime
- 1998-01-29 JP JP53271798A patent/JP4209948B2/ja not_active Expired - Fee Related
- 1998-01-29 WO PCT/JP1998/000371 patent/WO1998033514A1/ja active IP Right Grant
- 1998-01-29 AP APAP/P/1999/001602A patent/AP983A/en active
- 1998-01-29 SI SI9830798T patent/SI0972520T1/sl unknown
- 1998-01-29 PL PL98334852A patent/PL189381B1/pl not_active IP Right Cessation
- 1998-01-29 NZ NZ336509A patent/NZ336509A/xx not_active IP Right Cessation
- 1998-01-29 DE DE69831223T patent/DE69831223T9/de active Active
- 1998-01-29 HU HU0002386A patent/HU226554B1/hu not_active IP Right Cessation
- 1998-01-29 KR KR1019997006833A patent/KR100548107B1/ko not_active Expired - Fee Related
- 1998-01-29 ES ES98901044T patent/ES2244043T3/es not_active Expired - Lifetime
- 1998-01-29 RS YUP-349/99A patent/RS49691B/sr unknown
- 1998-01-29 IL IL13096798A patent/IL130967A0/xx active IP Right Grant
- 1998-01-29 AU AU56791/98A patent/AU737595B2/en not_active Ceased
- 1998-01-29 TR TR1999/01832T patent/TR199901832T2/xx unknown
- 1998-01-29 BR BRPI9807537-3A patent/BR9807537B1/pt not_active IP Right Cessation
1999
- 1999-07-15 IL IL130967A patent/IL130967A/en not_active IP Right Cessation
- 1999-07-29 NO NO19993702A patent/NO322334B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
DK0972520T3 (da)	2005-12-19
IL130967A (en)	2006-12-10
DE69831223T2 (de)	2006-02-16
KR20000070586A (ko)	2000-11-25
EP0972520B1 (en)	2005-08-17
AP983A (en)	2001-07-16
EP0972520A1 (en)	2000-01-19
ES2244043T3 (es)	2005-12-01
HUP0002386A3 (en)	2002-09-30
EP0972520A4 (en)	2002-11-05
EA001579B1 (ru)	2001-06-25
AU5679198A (en)	1998-08-25
NZ336509A (en)	2001-03-30
NO322334B1 (no)	2006-09-18
WO1998033514A1 (fr)	1998-08-06
NO993702D0 (no)	1999-07-29
AU737595B2 (en)	2001-08-23
YU34999A (sh)	2002-08-12
DE69831223D1 (de)	2005-09-22
KR100548107B1 (ko)	2006-02-02
HU226554B1 (en)	2009-03-30
IL130967A0 (en)	2001-01-28
BR9807537A (pt)	2000-03-21
EP0972520B9 (en)	2006-03-22
RS49691B (sr)	2007-12-31
ATE302021T1 (de)	2005-09-15
CN1152712C (zh)	2004-06-09
JP4209948B2 (ja)	2009-01-14
PL334852A1 (en)	2000-03-27
AP9901602A0 (en)	1999-09-30
SI0972520T1 (sl)	2006-02-28
NO993702L (no)	1999-09-29
DE69831223T9 (de)	2006-12-07
TR199901832T2 (xx)	1999-12-21
HUP0002386A2 (hu)	2000-11-28
CN1244127A (zh)	2000-02-09
CA2278546A1 (en)	1998-08-06
PL189381B1 (pl)	2005-07-29
EA199900694A1 (ru)	2000-04-24
CA2278546C (en)	2008-04-01

Publication	Publication Date	Title
DE69922576D1 (de)	2005-01-20	Applikator für Knochenmehltransplantate
BR9807848B1 (pt)	2013-11-05	Composto de arilsulfonamidas e análogos, bem como composição farmacêutica e uso dos mesmos.
BR9807502B1 (pt)	2008-11-18	compostos orgÂnicos, processo para sua preparaÇço, bem como composiÇço e aplicaÇço dos mesmos.
BR9810116B1 (pt)	2009-05-05	composição de solução e processo para sua preparação.
DE69801973D1 (de)	2001-11-15	Verfahren zur Herstellung von 1,1,1,3,3-Pentafluorpropan
BR9810829B1 (pt)	2009-08-11	composto heterocìclico, processo para preparar o mesmo, composição farmacêutica, e, uso de um composto ou de uma composição farmacêutica.
BR9810802B1 (pt)	2010-10-19	composto, composição farmacêutica, e, processo para a preparação de um composto.
FI990596A0 (fi)	1999-03-17	Luun morfogeneettiset proteiini-16 (BMP-16) -koostumukset
EE04438B1 (et)	2005-02-15	Bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline kompositsioon ja selle valmistamismeetod
BR9611675A (pt)	1999-02-23	Processo para preparação de uma composição de asfalto
EE04277B1 (et)	2004-04-15	Taksoidide klassi kuuluvate derivaatide valmistamismeetod
PT905254E (pt)	2006-08-31	Processo para a preparacao de uma polietilenoimina de baixo peso molecular.
TR199802394A3 (tr)	1999-06-21	Proteinleri stabilize etmek için gelistirilmis proses.
BR9807537B1 (pt)	2009-01-13	composição liofilizada de fator humano morfogenético ósseo mp52, bem como processo para sua preparação.
EE04681B1 (et)	2006-08-15	3,6-poolketaalid 9a-asaliidide klassist, nende valmistamismeetod ja farmatseutiline kompositsioon
BRPI9914571B1 (pt)	2011-10-18	composto, processo para sua preparação, uso do mesmo, bem como composição farmacêutica.
EP1023250A4 (en)	2001-03-21	METHOD FOR PRODUCING 2,6-DIALKYLNAPHTHALINE
PT977813E (pt)	2002-11-29	Processo para a preparacao de uma composicao asfaltica
EE03996B1 (et)	2003-04-15	Farmatseutilised kompositsioonid, nende valmistamismeetod ja kasutamine
EE04260B1 (et)	2004-04-15	Farmatseutiline kompositsioon, selle valmistamisemeetod ja kasutamine
MY120085A (en)	2005-08-30	Pyrido-thieno-diazepines, method for the production thereof and pharmaceutical compositions containing said pyrido-thieno-diazepines.
FI971081L (fi)	1997-05-06	Triatsolopyridatsiinit, menetelmä ja välituotteet niiden valmistamiseksi sekä niiden käyttö lääkeaineina
BR9703403B1 (pt)	2010-06-29	compostos, processo para preparação de compostos, utilização de composto e processo para preparação de composição farmacêutica.
EE200000336A (et)	2001-08-15	Ehhinokandiini derivaadid, nende valmistamismeetod, vaheühendid ja farmatseutilised kompositsioonid
CZ90898A3 (cs)	1998-10-14	Komorová nebo tunelová sušárna, jakož i předehřívač pro keramické polotovary

Legal Events

Date	Code	Title	Description
2005-03-08	B25D	Requested change of name of applicant approved
2005-03-15	B25A	Requested transfer of rights approved	Free format text: BIOPHAM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBH (DE)
2008-11-18	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2009-04-07	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 07/04/2009, OBSERVADAS AS CONDICOES LEGAIS.
2014-12-02	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 17A ANUIDADE.
2015-11-24	B24J	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)	Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2291 DE 02-12-2014 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.