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BR9702123A - Processo para a preparação de (-)- trans-n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3,4-(m etilenodióxi)fenóxi)metil)-piperidina - Google Patents

Processo para a preparação de (-)- trans-n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3,4-(m etilenodióxi)fenóxi)metil)-piperidina

Info

Publication number
BR9702123A
BR9702123A BR9702123-7A BR9702123A BR9702123A BR 9702123 A BR9702123 A BR 9702123A BR 9702123 A BR9702123 A BR 9702123A BR 9702123 A BR9702123 A BR 9702123A
Authority
BR
Brazil
Prior art keywords
pct
fluorophenyl
phenoxy
trans
methyl
Prior art date
Application number
BR9702123-7A
Other languages
English (en)
Inventor
Rafael Foguet
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of BR9702123A publication Critical patent/BR9702123A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Patente de Invenção: <B>"PROCESSO PARA A PREPARAçãO DE (-)-TRANS-N-p-FLUOROBENZOILMETIL-4-(p-FLUOROFENIL)-3-[[ 3,4-(METILENODIóXI)FENó-XI]METIL]-PIPERIDINA"<D>. O processo consise na reação do acetato de (-)-trans-N-(p-fluorofenil)-3-[[3,4-(metilenodióxi)fenóxi]metil]-piperidina com 2-cloro ou 2-bromo-4'-fluoroacetofenona, e o composto que dela resulta pode ser isolado como um sal de adição de forma farmacêutica aceitável, pela reação com o ácido correspondente.
BR9702123-7A 1996-02-29 1997-02-28 Processo para a preparação de (-)- trans-n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3,4-(m etilenodióxi)fenóxi)metil)-piperidina BR9702123A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09600481A ES2117557B1 (es) 1996-02-29 1996-02-29 Nuevo procedimiento de obtencion de (-)-trans -n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3- ((3,4-(metilendioxi)fenoxi ) metil)-piperidina.
PCT/EP1997/001007 WO1997031915A1 (en) 1996-02-29 1997-02-28 NEW PROCESS FOR PREPARING (-)-TRANS-N-p-FLUOROBENZOYLMETHYL-4-(p-FLUOROPHENYL)-3-[[3,4-(METHYLENEDIOXY)PHENOXY]METHYL]-PIPERIDINE

Publications (1)

Publication Number Publication Date
BR9702123A true BR9702123A (pt) 1999-12-28

Family

ID=8293999

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9702123-7A BR9702123A (pt) 1996-02-29 1997-02-28 Processo para a preparação de (-)- trans-n-p-fluorobenzoilmetil-4-(p-fluorofenil)-3,4-(m etilenodióxi)fenóxi)metil)-piperidina

Country Status (17)

Country Link
US (1) US5973155A (pt)
EP (1) EP0823907B1 (pt)
JP (1) JPH11504659A (pt)
AT (1) ATE180481T1 (pt)
AU (1) AU705887B2 (pt)
BR (1) BR9702123A (pt)
CA (1) CA2217171C (pt)
DE (1) DE69700236T2 (pt)
DK (1) DK0823907T3 (pt)
ES (1) ES2117557B1 (pt)
GR (1) GR3030683T3 (pt)
IL (1) IL121995A (pt)
NO (1) NO312549B1 (pt)
NZ (1) NZ328932A (pt)
TW (1) TW416941B (pt)
WO (1) WO1997031915A1 (pt)
ZA (1) ZA971074B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE03970B1 (et) * 1997-06-10 2003-02-17 Synthon B.V. 4-fenüülpiperidiinühend, selle valmistamine ja kasutamine ning seda sisaldav ravim
GB9808896D0 (en) * 1998-04-25 1998-06-24 Smithkline Beecham Plc Novel compound
CH689805A8 (fr) * 1998-07-02 2000-02-29 Smithkline Beecham Plc Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant.
AU2001290873B2 (en) * 2000-09-11 2006-07-27 Sepracor Inc. Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3426784A1 (de) * 1984-07-20 1986-01-30 Bosch Gmbh Robert Magnetoresistiver sensor zur abgabe von elektrischen signalen
DK231088D0 (da) * 1988-04-28 1988-04-28 Ferrosan As Piperidinforbindelser, deres fremstilling og anvendelse
ES2102295B1 (es) * 1994-03-18 1998-04-01 Ferrer Int Nuevos compuestos derivados de la n-benzoilmetil-piperidina.
GB2297550B (en) * 1995-02-06 1997-04-09 Smithkline Beecham Plc Paroxetine hydrochloride anhydrate substantially free of bound organic solvent
WO1996036636A1 (en) * 1995-05-17 1996-11-21 Novo Nordisk A/S Process for preparing 4-aryl-piperidine derivatives

Also Published As

Publication number Publication date
EP0823907B1 (en) 1999-05-26
AU705887B2 (en) 1999-06-03
CA2217171A1 (en) 1997-09-04
IL121995A (en) 2001-01-28
JPH11504659A (ja) 1999-04-27
ES2117557B1 (es) 1999-07-01
DE69700236T2 (de) 1999-09-30
NO974958L (no) 1997-10-27
NO974958D0 (no) 1997-10-27
DE69700236D1 (de) 1999-07-01
IL121995A0 (en) 1998-03-10
ATE180481T1 (de) 1999-06-15
CA2217171C (en) 2001-09-11
WO1997031915A1 (en) 1997-09-04
US5973155A (en) 1999-10-26
NO312549B1 (no) 2002-05-27
TW416941B (en) 2001-01-01
AU2094097A (en) 1997-09-16
NZ328932A (en) 1998-04-27
GR3030683T3 (en) 1999-11-30
ZA971074B (en) 1997-11-18
DK0823907T3 (da) 1999-11-08
ES2117557A1 (es) 1998-08-01
EP0823907A1 (en) 1998-02-18

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]