BR9507597A - Variantes de subtilisina bpn tendo adsorção diminuída e hidrólise aumentada - Google Patents
Variantes de subtilisina bpn tendo adsorção diminuída e hidrólise aumentadaInfo
- Publication number
- BR9507597A BR9507597A BR9507597A BR9507597A BR9507597A BR 9507597 A BR9507597 A BR 9507597A BR 9507597 A BR9507597 A BR 9507597A BR 9507597 A BR9507597 A BR 9507597A BR 9507597 A BR9507597 A BR 9507597A
- Authority
- BR
- Brazil
- Prior art keywords
- variants
- subtilisin bpn
- increased hydrolysis
- decreased adsorption
- adsorption
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38609—Protease or amylase in solid compositions only
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Detergent Compositions (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23793994A | 1994-05-02 | 1994-05-02 | |
US28746194A | 1994-08-11 | 1994-08-11 | |
US08/394,011 US6436690B1 (en) | 1993-09-15 | 1995-03-03 | BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted |
PCT/US1995/003176 WO1995030010A1 (en) | 1994-05-02 | 1995-03-16 | Subtilisin bpn' variants having decreased adsorption and increased hydrolysis |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9507597A true BR9507597A (pt) | 1997-10-07 |
Family
ID=27399035
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9507597A BR9507597A (pt) | 1994-05-02 | 1995-03-16 | Variantes de subtilisina bpn tendo adsorção diminuída e hidrólise aumentada |
Country Status (13)
Country | Link |
---|---|
US (1) | US6436690B1 (pt) |
EP (1) | EP0758388A1 (pt) |
JP (1) | JPH09511652A (pt) |
CN (1) | CN1151761A (pt) |
AU (1) | AU2159195A (pt) |
BR (1) | BR9507597A (pt) |
CA (1) | CA2189426C (pt) |
CZ (1) | CZ321696A3 (pt) |
HU (1) | HUT75559A (pt) |
IL (1) | IL113048A0 (pt) |
MX (1) | MX9605357A (pt) |
PE (1) | PE27897A1 (pt) |
WO (1) | WO1995030010A1 (pt) |
Families Citing this family (88)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6436690B1 (en) * | 1993-09-15 | 2002-08-20 | The Procter & Gamble Company | BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted |
US6440717B1 (en) * | 1993-09-15 | 2002-08-27 | The Procter & Gamble Company | BPN′ variants having decreased adsorption and increased hydrolysis |
US6599730B1 (en) * | 1994-05-02 | 2003-07-29 | Procter & Gamble Company | Subtilisin 309 variants having decreased adsorption and increased hydrolysis |
US5837516A (en) * | 1995-03-03 | 1998-11-17 | Genentech, Inc. | Subtilisin variants capable of cleaving substrates containing basic residues |
US5780285A (en) * | 1995-03-03 | 1998-07-14 | Genentech, Inc. | Subtilisin variants capable of cleaving substrates containing dibasic residues |
US6455295B1 (en) * | 1995-03-08 | 2002-09-24 | The Procter & Gamble Company | Subtilisin Carlsberg variants having decreased adsorption and increased hydrolysis |
US6475765B1 (en) | 1995-03-09 | 2002-11-05 | Procter & Gamble Company | Subtilisin DY variants having decreased adsorption and increased hydrolysis |
IL117350A0 (en) * | 1995-03-09 | 1996-07-23 | Procter & Gamble | Proteinase k variants having decreased adsorption and increased hydrolysis |
US6682924B1 (en) * | 1995-05-05 | 2004-01-27 | Novozymes A/S | Protease variants and compositions |
DE19535082A1 (de) | 1995-09-21 | 1997-03-27 | Henkel Ecolab Gmbh & Co Ohg | Pastenförmiges Wasch- und Reinigungsmittel |
DE19615776A1 (de) | 1996-04-20 | 1997-10-23 | Henkel Kgaa | Löslichkeitsverbessertes Enzymgranulat |
DE19636035A1 (de) | 1996-09-05 | 1998-03-12 | Henkel Ecolab Gmbh & Co Ohg | Pastenförmiges Wasch- und Reinigungsmittel |
US6300116B1 (en) * | 1996-11-04 | 2001-10-09 | Novozymes A/S | Modified protease having improved autoproteolytic stability |
EP2278001B1 (en) | 1996-11-04 | 2013-10-23 | Novozymes A/S | Protease variants and compositions |
DE19703364A1 (de) | 1997-01-30 | 1998-08-06 | Henkel Ecolab Gmbh & Co Ohg | Pastenförmiges Wasch- und Reinigungsmittel |
US6284246B1 (en) | 1997-07-30 | 2001-09-04 | The Procter & Gamble Co. | Modified polypeptides with high activity and reduced allergenicity |
CN1272137A (zh) | 1997-08-29 | 2000-11-01 | 诺沃挪第克公司 | 蛋白酶变体及组合物 |
AU8798198A (en) | 1997-08-29 | 1999-03-22 | Novo Nordisk A/S | Protease variants and compositions |
EP0913458B1 (en) * | 1997-10-22 | 2004-06-16 | The Procter & Gamble Company | Liquid hard-surface cleaning compositions |
AR015977A1 (es) | 1997-10-23 | 2001-05-30 | Genencor Int | Variantes de proteasa multiplemente substituida con carga neta alterada para su empleo en detergentes |
ES2367505T3 (es) * | 1997-10-23 | 2011-11-04 | Danisco Us Inc. | Variantes de proteasa con sustituciones múltiples con carga neta alterada para usar en detergentes. |
WO1999027082A1 (en) | 1997-11-21 | 1999-06-03 | Novo Nordisk A/S | Protease variants and compositions |
US6773907B2 (en) | 1997-11-21 | 2004-08-10 | Peter Kamp Hansen | Subtilase enzymes |
US6780629B2 (en) | 1997-11-21 | 2004-08-24 | Novozymes A/S | Subtilase enzymes |
AU2742499A (en) | 1998-03-26 | 1999-10-18 | Procter & Gamble Company, The | Serine protease variants having amino acid substitutions |
US6908757B1 (en) | 1998-03-26 | 2005-06-21 | The Procter & Gamble Company | Serine protease variants having amino acid deletions and substitutions |
US6495136B1 (en) | 1998-03-26 | 2002-12-17 | The Procter & Gamble Company | Proteases having modified amino acid sequences conjugated to addition moieties |
JP2002526434A (ja) * | 1998-09-22 | 2002-08-20 | ザ、プロクター、エンド、ギャンブル、カンパニー | 水不溶性基質と結合したサブチリシン酵素を含有するパーソナルケア組成物 |
US6376450B1 (en) | 1998-10-23 | 2002-04-23 | Chanchal Kumar Ghosh | Cleaning compositions containing multiply-substituted protease variants |
US6831053B1 (en) | 1998-10-23 | 2004-12-14 | The Procter & Gamble Company | Bleaching compositions comprising multiply-substituted protease variants |
DE19857687A1 (de) | 1998-12-15 | 2000-06-21 | Henkel Ecolab Gmbh & Co Ohg | Pastenförmiges Waschmittel |
AU772993B2 (en) * | 1998-12-18 | 2004-05-13 | Novozymes A/S | Subtilase enzymes of the I-S1 and I-S2 sub-groups having an additional amino acid residue in an active site loop region |
ATE504651T1 (de) | 1998-12-18 | 2011-04-15 | Novozymes As | Subtilase enzyme der i-s1- und i-s2-untergruppen mit einem zusätzlichen aminosäurerest in einer aktiven schleifenregion |
WO2000071687A1 (en) | 1999-05-20 | 2000-11-30 | Novozymes A/S | Subtilase enzymes of the i-s1 and i-s2 sub-groups having at least one additional amino acid residue between positions 129 and 130 |
JP5563180B2 (ja) † | 1999-05-20 | 2014-07-30 | ノボザイムス アクティーゼルスカブ | 97位と98位との間に少なくとも1個の追加のアミノ酸残基を有するi−s1及びi−s2サブグループのズブチラーゼ酵素 |
DE60040287D1 (de) † | 1999-05-20 | 2008-10-30 | Novozymes As | Subtilase enzyme der i-s1 und i-s2 untergruppen mit mindestens einer zusätzlichen aminosäure zwischen position 128 und 129 |
DE60040149D1 (de) | 1999-05-20 | 2008-10-16 | Novozymes As | Subtilase-enzyme der i-s1 und i-s2 untergruppen mit wenigstens einem zusätzlichen aminosäurerest zwischen positionen 126 und 127 |
DE60039693D1 (de) | 1999-05-20 | 2008-09-11 | Novozymes As | Subtilase-enzyme der i-s1 und i-s2 untergruppen mit wenigstens einem zusätzlichen aminosäurerest zwischen positionen 125 und 126 |
DE60040285D1 (de) | 1999-05-20 | 2008-10-30 | Novozymes As | Subtilase enzyme der i-s1 und i-s2 untergruppen mit mindestens einer zusätzlichen aminosäure zwischen position 127 und 128 |
DE60040282D1 (de) | 1999-05-20 | 2008-10-30 | Novozymes As | SUBTILASE ENZYME DER I-S1 UND I-S2 UNTERGRUPPEN MIT MINDESTENS EINER ZUSäTZLICHEN AMINOSäURE ZWISCHEN POSITION 132 UND 133 |
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ATE407202T1 (de) | 2003-05-07 | 2008-09-15 | Novozymes As | Enzymvarianten von subtilisin (subtilasen) |
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JPH04500384A (ja) | 1989-06-26 | 1992-01-23 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 酵素洗剤組成物 |
DK316989D0 (da) | 1989-06-26 | 1989-06-26 | Novo Nordisk As | Enzymer |
US5352603A (en) * | 1989-08-31 | 1994-10-04 | Kali-Chemie Ag | Highly alkaline proteases |
US6271012B1 (en) * | 1989-10-11 | 2001-08-07 | Genencor International, Inc. | Protease muteins and their use in detergents |
DE4009534A1 (de) * | 1990-03-24 | 1991-09-26 | Henkel Kgaa | Fluessiges handreinigungsmittel |
DK97190D0 (da) * | 1990-04-19 | 1990-04-19 | Novo Nordisk As | Oxidationsstabile detergentenzymer |
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DK271490D0 (da) * | 1990-11-14 | 1990-11-14 | Novo Nordisk As | Detergentkomposition |
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DK0563169T3 (da) | 1990-12-21 | 1998-05-18 | Novo Nordisk As | Enzymmutanter med lille variation i molekylær ladning i et pH område |
US5340735A (en) * | 1991-05-29 | 1994-08-23 | Cognis, Inc. | Bacillus lentus alkaline protease variants with increased stability |
DE4224125A1 (de) * | 1991-07-27 | 1993-01-28 | Solvay Enzymes Gmbh & Co Kg | Verfahren zur verbesserung der stabilitaet von enzymen und stabilisierte enzyme |
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US5470733A (en) * | 1993-06-01 | 1995-11-28 | University Of Maryland | Calcium free subtilisin mutants |
US5567601A (en) * | 1993-06-01 | 1996-10-22 | University Of Maryland | Subtilisin mutants lacking a primary calcium binding site |
CA2170491C (en) | 1993-09-15 | 2001-10-30 | Philip Frederick Brode, Iii | Subtilisin bpn' variants with decreased adsorption and increased hydrolysis |
US6436690B1 (en) * | 1993-09-15 | 2002-08-20 | The Procter & Gamble Company | BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted |
DE69434962T2 (de) * | 1993-10-14 | 2008-01-17 | The Procter & Gamble Company, Cincinnati | Proteasehaltige reinigungsmittel |
BR9407833A (pt) * | 1993-10-14 | 1997-05-13 | Procter & Gamble | Composições alvejantes compreendendo enzimas protease |
ES2364774T3 (es) * | 1994-02-24 | 2011-09-14 | HENKEL AG & CO. KGAA | Enzimas mejoradas y detergentes que las contienen. |
US6599730B1 (en) * | 1994-05-02 | 2003-07-29 | Procter & Gamble Company | Subtilisin 309 variants having decreased adsorption and increased hydrolysis |
US5780285A (en) * | 1995-03-03 | 1998-07-14 | Genentech, Inc. | Subtilisin variants capable of cleaving substrates containing dibasic residues |
-
1995
- 1995-03-03 US US08/394,011 patent/US6436690B1/en not_active Expired - Fee Related
- 1995-03-16 HU HU9603031A patent/HUT75559A/hu unknown
- 1995-03-16 EP EP95914713A patent/EP0758388A1/en not_active Withdrawn
- 1995-03-16 CN CN95193941A patent/CN1151761A/zh active Pending
- 1995-03-16 MX MX9605357A patent/MX9605357A/es unknown
- 1995-03-16 CA CA002189426A patent/CA2189426C/en not_active Expired - Fee Related
- 1995-03-16 CZ CZ963216A patent/CZ321696A3/cs unknown
- 1995-03-16 WO PCT/US1995/003176 patent/WO1995030010A1/en not_active Application Discontinuation
- 1995-03-16 BR BR9507597A patent/BR9507597A/pt not_active Application Discontinuation
- 1995-03-16 JP JP7528205A patent/JPH09511652A/ja not_active Ceased
- 1995-03-16 AU AU21591/95A patent/AU2159195A/en not_active Abandoned
- 1995-03-20 IL IL11304895A patent/IL113048A0/xx unknown
- 1995-04-03 PE PE1995265539A patent/PE27897A1/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN1151761A (zh) | 1997-06-11 |
WO1995030010A1 (en) | 1995-11-09 |
PE27897A1 (es) | 1997-08-13 |
CZ321696A3 (en) | 1997-05-14 |
JPH09511652A (ja) | 1997-11-25 |
HU9603031D0 (en) | 1997-01-28 |
US6436690B1 (en) | 2002-08-20 |
CA2189426C (en) | 2002-09-17 |
CA2189426A1 (en) | 1995-11-09 |
EP0758388A1 (en) | 1997-02-19 |
MX9605357A (es) | 1997-12-31 |
HUT75559A (en) | 1997-05-28 |
AU2159195A (en) | 1995-11-29 |
IL113048A0 (en) | 1995-06-29 |
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