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BR112015016391A2 - carboxamidas i baseadas em pirazolil como inibidoras do canal crac - Google Patents

carboxamidas i baseadas em pirazolil como inibidoras do canal crac

Info

Publication number
BR112015016391A2
BR112015016391A2 BR112015016391A BR112015016391A BR112015016391A2 BR 112015016391 A2 BR112015016391 A2 BR 112015016391A2 BR 112015016391 A BR112015016391 A BR 112015016391A BR 112015016391 A BR112015016391 A BR 112015016391A BR 112015016391 A2 BR112015016391 A2 BR 112015016391A2
Authority
BR
Brazil
Prior art keywords
pyrazolyl
crac channel
channel inhibitors
carboxamides
compounds
Prior art date
Application number
BR112015016391A
Other languages
English (en)
Inventor
Kless Achim
Voss Felix
Wachten Sebastian
Nordhoff Sonja
Ritter Stefanie
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of BR112015016391A2 publication Critical patent/BR112015016391A2/pt

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    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract

resumo carboxamidas i baseadas em pirazolil como inibidoras do canal crac a invenção está relacionada a compostos de carboxamida baseados em pirazolil úteis como inibidores icrac, a composições farmacêuticas que contêm esses compostos e também a esses compostos para uso no tratamento e/ou profilaxia de doenças e/ou disfunções, em particular doenças e/ou disfunções inflamatórias. 1/1
BR112015016391A 2013-01-10 2014-01-10 carboxamidas i baseadas em pirazolil como inibidoras do canal crac BR112015016391A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13000118 2013-01-10
PCT/EP2014/000043 WO2014108337A1 (en) 2013-01-10 2014-01-10 Pyrazolyl-based carboxamides i as crac channel inhibitors

Publications (1)

Publication Number Publication Date
BR112015016391A2 true BR112015016391A2 (pt) 2017-07-11

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Application Number Title Priority Date Filing Date
BR112015016391A BR112015016391A2 (pt) 2013-01-10 2014-01-10 carboxamidas i baseadas em pirazolil como inibidoras do canal crac

Country Status (14)

Country Link
US (1) US9206136B2 (pt)
EP (1) EP2943196A1 (pt)
JP (1) JP2016508152A (pt)
KR (1) KR20150103751A (pt)
CN (1) CN104994851A (pt)
AR (1) AR094412A1 (pt)
AU (1) AU2014204978A1 (pt)
BR (1) BR112015016391A2 (pt)
CA (1) CA2897562A1 (pt)
EA (1) EA201500736A1 (pt)
HK (1) HK1216300A1 (pt)
IL (1) IL239790A0 (pt)
MX (1) MX2015008919A (pt)
WO (1) WO2014108337A1 (pt)

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TWI795381B (zh) 2016-12-21 2023-03-11 比利時商健生藥品公司 作為ｍａｌｔ１抑制劑之吡唑衍生物
WO2019081477A1 (de) 2017-10-26 2019-05-02 Bayer Cropscience Aktiengesellschaft Substituierte pyrazole sowie deren salze und ihre verwendung als herbizide wirkstoffe
WO2019081485A1 (de) 2017-10-26 2019-05-02 Bayer Cropscience Aktiengesellschaft Substituierte pyrazole sowie deren salze und ihre verwendung als herbizide wirkstoffe
BR112021004893A2 (pt) 2018-09-14 2021-06-01 Rhizen Pharmaceuticals A G composições compreendendo um inibidor de crac e um corticosteroide e métodos de uso dos mesmos
CN116847837A (zh) * 2020-11-13 2023-10-03 钙医学公司 Crac通道抑制剂的改进合成

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MX2015008919A (es) 2015-10-22
WO2014108337A1 (en) 2014-07-17
AR094412A1 (es) 2015-07-29
KR20150103751A (ko) 2015-09-11
AU2014204978A1 (en) 2015-08-20
CN104994851A (zh) 2015-10-21
HK1216300A1 (zh) 2016-11-04
WO2014108337A8 (en) 2015-07-23
CA2897562A1 (en) 2014-07-17
JP2016508152A (ja) 2016-03-17
EP2943196A1 (en) 2015-11-18
IL239790A0 (en) 2015-08-31
EA201500736A1 (ru) 2016-04-29
US20140194443A1 (en) 2014-07-10

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