BR112013017172A2 - variantes de plasminogênio e plasmina - Google Patents
variantes de plasminogênio e plasminaInfo
- Publication number
- BR112013017172A2 BR112013017172A2 BR112013017172A BR112013017172A BR112013017172A2 BR 112013017172 A2 BR112013017172 A2 BR 112013017172A2 BR 112013017172 A BR112013017172 A BR 112013017172A BR 112013017172 A BR112013017172 A BR 112013017172A BR 112013017172 A2 BR112013017172 A2 BR 112013017172A2
- Authority
- BR
- Brazil
- Prior art keywords
- plasminogen
- plasmin variants
- plasmin
- variants
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6435—Plasmin (3.4.21.7), i.e. fibrinolysin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/484—Plasmin (3.4.21.7)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Cell Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161429868P | 2011-01-05 | 2011-01-05 | |
| EP11150246 | 2011-01-05 | ||
| PCT/EP2012/050074 WO2012093132A1 (en) | 2011-01-05 | 2012-01-04 | Plasminogen and plasmin variants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013017172A2 true BR112013017172A2 (pt) | 2016-10-11 |
Family
ID=45470557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013017172A BR112013017172A2 (pt) | 2011-01-05 | 2012-01-04 | variantes de plasminogênio e plasmina |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9121014B2 (pt) |
| EP (1) | EP2661493B1 (pt) |
| JP (1) | JP6085568B2 (pt) |
| KR (1) | KR20140015289A (pt) |
| CN (1) | CN103384722B (pt) |
| AU (1) | AU2012204874B9 (pt) |
| BR (1) | BR112013017172A2 (pt) |
| CA (1) | CA2823491A1 (pt) |
| DK (1) | DK2661493T3 (pt) |
| ES (1) | ES2583082T3 (pt) |
| IL (1) | IL227007A (pt) |
| MX (1) | MX337248B (pt) |
| RU (1) | RU2604807C2 (pt) |
| WO (1) | WO2012093132A1 (pt) |
| ZA (1) | ZA201304937B (pt) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2451835A1 (en) | 2009-07-10 | 2012-05-16 | ThromboGenics N.V. | Variants of plasminogen and plasmin |
| US20120189609A1 (en) | 2009-08-28 | 2012-07-26 | Thrombogenics Nv | Improvement to trabeculectomy |
| MX337248B (es) | 2011-01-05 | 2016-02-19 | Thrombogenics Nv | Variantes de plasminogeno y plasmina. |
| EP2741767A1 (en) | 2011-08-12 | 2014-06-18 | ThromboGenics N.V. | Plasminogen and plasmin variants |
| CN106609266B (zh) * | 2015-10-27 | 2020-09-11 | 江苏恒瑞医药股份有限公司 | 一种微纤溶酶原变体及通过其得到的微纤溶酶变体 |
| TW201722464A (zh) | 2015-11-10 | 2017-07-01 | 波麥堤克生化科學有限公司 | 用於傷口癒合之纖維蛋白溶酶原給藥方案 |
| US11338022B2 (en) | 2015-12-18 | 2022-05-24 | Talengen International Limited | Method for preventing and treating angiocardiopathy |
| CA3008691A1 (en) | 2015-12-18 | 2017-06-22 | Talengen International Limited | Method for preventing or treating diabetic retinopathy |
| WO2017101867A1 (zh) | 2015-12-18 | 2017-06-22 | 深圳瑞健生命科学研究院有限公司 | 一种预防或治疗糖尿病性神经损伤及其相关病症的方法 |
| EP3395354B1 (en) * | 2015-12-18 | 2024-05-22 | Talengen International Limited | Plasminogen for use in treating diabetic nephropathy |
| CA3047177A1 (en) | 2016-12-15 | 2018-06-21 | Talengen International Limited | Method for promoting expression of insulin receptor substrate-2 |
| WO2018107688A1 (zh) * | 2016-12-15 | 2018-06-21 | 深圳瑞健生命科学研究院有限公司 | 一种预防和治疗脂肪肝的方法 |
| TWI677348B (zh) | 2016-12-15 | 2019-11-21 | 大陸商深圳瑞健生命科學研究院有限公司 | 一種改善心臟病變的方法 |
| TWI657823B (zh) | 2016-12-15 | 2019-05-01 | 大陸商深圳瑞健生命科學研究院有限公司 | 一種預防和治療系統性硬化症的方法 |
| US11207387B2 (en) | 2016-12-15 | 2021-12-28 | Talengen International Limited | Method and drug for preventing and treating obesity |
| TW202123962A (zh) * | 2016-12-15 | 2021-07-01 | 大陸商深圳瑞健生命科學研究院有限公司 | 一種預防和治療腎纖維化的方法 |
| CN108210904A (zh) * | 2016-12-15 | 2018-06-29 | 深圳瑞健生命科学研究院有限公司 | 治疗动脉粥样硬化及其并发症的药物及其用途 |
| WO2018233604A1 (zh) | 2017-06-19 | 2018-12-27 | 泰伦基国际有限公司 | 一种调控glp-1/glp-1r的方法和药物 |
| US12226462B2 (en) | 2019-01-25 | 2025-02-18 | Council Of Scientific & Industrial Research | Fibrinolytic composition and method of its preparation |
| CN110066783B (zh) * | 2019-05-16 | 2021-07-13 | 重庆派金生物科技有限公司 | 一种无自切形式的微纤溶酶制备方法 |
| EP4281471A4 (en) * | 2021-01-20 | 2025-01-15 | Univ Monash | FUSION PROTEINS |
| CN113755476B (zh) * | 2021-10-14 | 2023-04-11 | 北京农学院 | 蛆激酶制备方法及其用途 |
| CN114736948B (zh) * | 2022-06-10 | 2022-11-08 | 深圳市帝迈生物技术有限公司 | 一种α2-抗纤溶酶活性测定试剂盒 |
Family Cites Families (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3208908A (en) | 1961-11-16 | 1965-09-28 | Parke Davis & Co | Fibrinolysin-desoxyribonuclease for enzymatic debridement |
| US4122158A (en) | 1976-09-23 | 1978-10-24 | Alza Corporation | Topical therapeutic preparations |
| NZ191320A (en) | 1978-09-07 | 1982-09-14 | Beecham Group Ltd | In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions |
| IT1194135B (it) | 1981-01-05 | 1988-09-14 | Novo Industri As | Composizioni di plasmina stabilizzata e metodo per la loro preparazione |
| US4774087A (en) | 1987-08-14 | 1988-09-27 | Northwestern University | Micro-size fibrinolytic plasmin |
| WO1990013640A1 (en) | 1989-05-01 | 1990-11-15 | The University Of Notre Dame Du Lac | Methods and materials for expression of human plasminogen in a eukaryotic cell system |
| US5087572A (en) | 1989-12-01 | 1992-02-11 | Genentech, Inc. | Dna encoding human plasminogen modified at the cleavage site |
| AT402367B (de) | 1990-10-11 | 1997-04-25 | Immuno Ag | Pharmazeutische zubereitung auf basis von lys-plasminogen |
| US5288489A (en) | 1991-08-28 | 1994-02-22 | Orion Therapeutic Systems, Inc. | Fibrinolysis and fibrinogenolysis treatment |
| IT1260468B (it) | 1992-01-29 | 1996-04-09 | Metodo per mantenere l'attivita' di enzimi proteolitici modificati con polietilenglicole | |
| US5304118A (en) | 1992-12-16 | 1994-04-19 | Trese Michael T | Method for performing a vitrectomy on an eye |
| US5520912A (en) | 1993-07-02 | 1996-05-28 | Immuno Aktiengesellschaft | Prevention and treatment of ischemic events and reperfusion injury resulting therefrom using lys-plasminogen |
| DE4411143C2 (de) | 1994-03-30 | 1996-08-01 | Immuno Ag | Thrombosemittel |
| EP0835931A4 (en) | 1995-06-26 | 2000-11-15 | Daiichi Pure Chemicals Co Ltd | STABLE PLASMINE SOLUTION |
| CN1152962C (zh) | 1996-05-03 | 2004-06-09 | 艾博特公司 | 新型抗血管生成肽、其编码多核苷酸和抑制血管生成的方法 |
| ES2276536T3 (es) | 1998-09-29 | 2007-06-16 | LEUVEN RESEARCH & DEVELOPMENT VZW | Uso de compuestos que reducen las alfas2-antiplasminas in vivo para la preparacion de una composicion para el tratamiento del ictus isquemico. |
| US6899877B2 (en) | 1999-03-09 | 2005-05-31 | Minu, L.L.C. | Process for generating plasmin in the vitreous of the eye and inducing separation of the posterior hyaloid from the retina |
| US6585972B2 (en) | 1999-03-09 | 2003-07-01 | Gholam A. Peyman | Process for crosslinking of collagen in the vitreous of the eye and inducing separation of the posterior hyaloid from the retina |
| US20040081643A1 (en) | 1999-03-09 | 2004-04-29 | Peyman Gholam A. | Process for inhibiting vascular proliferation in the eye |
| US6733750B1 (en) | 1999-03-09 | 2004-05-11 | Minu, L.L.C. | Process and composition for inducing posterior vitreous detachment |
| DK1194528T3 (da) | 1999-07-14 | 2007-07-09 | D Collen Res Foundation Vzw | Monoklonalt antistof mod faktor VII, hvilket antistof selv ved forekomst i molært overskud kun delvist inaktiverer faktor VII, samt fremgangsmåde til produktion af et sådant antistof |
| WO2005016455A2 (en) | 2003-08-14 | 2005-02-24 | D. Collen Research Foundation Vzw | Antibodies against factor viii with modified glycosylation in the variable region |
| US6440414B1 (en) | 1999-10-01 | 2002-08-27 | Amgen Inc. | Pharmaceutical compositions of fibrinolytic agent |
| US6964764B2 (en) | 1999-11-13 | 2005-11-15 | Talecris Biotherapeutics, Inc. | Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin |
| US6355243B1 (en) | 1999-11-13 | 2002-03-12 | Bayer Corporation | Method of thrombolysis by local delivery of active plasmin |
| US7544500B2 (en) | 1999-11-13 | 2009-06-09 | Talecris Biotherapeutics, Inc. | Process for the production of a reversibly inactive acidified plasmin composition |
| US6969515B2 (en) | 1999-11-13 | 2005-11-29 | Talecris Biotherapeutics, Inc. | Method of thrombolysis by local delivery of reversibly inactivated acidified plasmin |
| EP1263452A4 (en) | 2000-02-08 | 2006-12-20 | Univ Northwestern | METHODS AND COMPOSITIONS FOR PRODUCING ANGIOSTATIN |
| AU2002218890A1 (en) | 2000-12-21 | 2002-07-01 | Thromb-X N.V. | A yeast expression vector and a method of making a recombinant protein by expression in a yeast cell |
| US20020139378A1 (en) | 2001-03-28 | 2002-10-03 | Trese Michael T. | Method for creating a separation of posterior cortical vitreous from the retina of the eye |
| DE10153601A1 (de) * | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA zur Behandlung von Schlaganfall |
| US20040009212A1 (en) | 2002-01-30 | 2004-01-15 | Pharma Power Biotec Co. Ltd. | Mucoadhesive thermoresponsive medicament-carrier composition |
| CA2475277A1 (en) | 2002-02-06 | 2003-08-14 | Trommsdorff Gmbh & Co. Kg Arzneimittel | Method for producing recombinant proteins in micro-organisms |
| US7776026B2 (en) | 2002-02-06 | 2010-08-17 | Nuvue Technologies, Inc. | Method for vitreous liquefaction |
| US6787135B2 (en) | 2002-03-13 | 2004-09-07 | William Beaumont Hospital | Modification of vitreal matrix metalloproteinase activity |
| US20040235115A1 (en) | 2002-11-18 | 2004-11-25 | Reed Guy L. | Compositions and methods for treating thrombotic disorders |
| GB0228409D0 (en) | 2002-12-06 | 2003-01-08 | Thromb X Nv | Pharmacological vitreolysis |
| CN1938427A (zh) | 2004-02-11 | 2007-03-28 | 比奥莱克斯公司 | 纤溶酶原和微纤溶酶原在浮萍中的表达 |
| CN1253560C (zh) | 2004-03-01 | 2006-04-26 | 宁夏大学 | 组织型纤溶酶原激活剂缺失/点突变体基因转染细胞株 |
| DE602005022692D1 (de) | 2004-04-22 | 2010-09-16 | Talecris Biotherapeutics Inc | Recombinant modifiziertes plasmin |
| US20060257391A1 (en) | 2005-05-11 | 2006-11-16 | Bausch & Lomb Incorporated | Non-surgical method for preventing or reducing the rate of the progression of non-proliferative diabetic retinopathy and the treatment of other ocular conditions |
| US8231869B2 (en) | 2005-10-20 | 2012-07-31 | Grifols Therapeutics Inc. | Recombinant plasmin for opthalmic indications |
| US20070134231A1 (en) | 2005-12-13 | 2007-06-14 | Jani Dharmendra M | Method for prolonging activity of autodegradable enzymes and compositions thereof |
| US20070134230A1 (en) | 2005-12-13 | 2007-06-14 | Jani Dharmendra M | Method for prolonging activity of autodegradable enzymes |
| US20070196350A1 (en) | 2006-02-22 | 2007-08-23 | Bartels Stephen P | Compositions and Methods for Effecting Controlled Posterior Vitreous Detachment |
| US20070212358A1 (en) | 2006-03-10 | 2007-09-13 | Bartels Stephen P | Compositions and Methods for Effecting Controlled Posterior Vitreous Detachment |
| CN101573134B (zh) | 2006-08-28 | 2013-03-06 | 李季男 | 抗感染候选药物 |
| WO2008054592A2 (en) | 2006-09-29 | 2008-05-08 | Proteomtech, Inc. | Methods for production of recombinant plasminogen and plasmin polypeptides |
| JP5539896B2 (ja) | 2007-11-29 | 2014-07-02 | グリフオルス・セラピユーテイクス・インコーポレーテツド | 組換え的に改変されたプラスミン |
| WO2009073457A1 (en) | 2007-11-30 | 2009-06-11 | Bausch & Lomb Incorporated | Methods and compositions for the rescue of a filtering bleb |
| EP2451835A1 (en) | 2009-07-10 | 2012-05-16 | ThromboGenics N.V. | Variants of plasminogen and plasmin |
| US20120189609A1 (en) | 2009-08-28 | 2012-07-26 | Thrombogenics Nv | Improvement to trabeculectomy |
| MX337248B (es) | 2011-01-05 | 2016-02-19 | Thrombogenics Nv | Variantes de plasminogeno y plasmina. |
| EP2741767A1 (en) | 2011-08-12 | 2014-06-18 | ThromboGenics N.V. | Plasminogen and plasmin variants |
-
2012
- 2012-01-04 MX MX2013007791A patent/MX337248B/es active IP Right Grant
- 2012-01-04 US US13/977,836 patent/US9121014B2/en not_active Expired - Fee Related
- 2012-01-04 DK DK12700154.3T patent/DK2661493T3/en active
- 2012-01-04 CN CN201280004750.5A patent/CN103384722B/zh not_active Expired - Fee Related
- 2012-01-04 JP JP2013547848A patent/JP6085568B2/ja not_active Expired - Fee Related
- 2012-01-04 CA CA2823491A patent/CA2823491A1/en not_active Abandoned
- 2012-01-04 KR KR1020137017313A patent/KR20140015289A/ko not_active Withdrawn
- 2012-01-04 BR BR112013017172A patent/BR112013017172A2/pt not_active IP Right Cessation
- 2012-01-04 RU RU2013132746/10A patent/RU2604807C2/ru not_active IP Right Cessation
- 2012-01-04 ES ES12700154.3T patent/ES2583082T3/es active Active
- 2012-01-04 WO PCT/EP2012/050074 patent/WO2012093132A1/en active Application Filing
- 2012-01-04 EP EP12700154.3A patent/EP2661493B1/en active Active
- 2012-01-04 AU AU2012204874A patent/AU2012204874B9/en not_active Ceased
-
2013
- 2013-06-17 IL IL227007A patent/IL227007A/en not_active IP Right Cessation
- 2013-07-02 ZA ZA2013/04937A patent/ZA201304937B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2604807C2 (ru) | 2016-12-10 |
| NZ612836A (en) | 2014-12-24 |
| DK2661493T3 (en) | 2016-07-18 |
| ZA201304937B (en) | 2014-03-26 |
| CN103384722B (zh) | 2016-11-16 |
| AU2012204874B9 (en) | 2014-10-30 |
| CA2823491A1 (en) | 2012-07-12 |
| AU2012204874B2 (en) | 2014-08-21 |
| MX2013007791A (es) | 2013-08-21 |
| WO2012093132A1 (en) | 2012-07-12 |
| EP2661493A1 (en) | 2013-11-13 |
| MX337248B (es) | 2016-02-19 |
| RU2013132746A (ru) | 2015-01-27 |
| KR20140015289A (ko) | 2014-02-06 |
| IL227007A (en) | 2016-06-30 |
| CN103384722A (zh) | 2013-11-06 |
| JP2014504867A (ja) | 2014-02-27 |
| EP2661493B1 (en) | 2016-03-30 |
| AU2012204874A1 (en) | 2013-05-02 |
| ES2583082T3 (es) | 2016-09-19 |
| JP6085568B2 (ja) | 2017-02-22 |
| US20130273028A1 (en) | 2013-10-17 |
| US9121014B2 (en) | 2015-09-01 |
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