[go: up one dir, main page]

BR112012031295A2 - modified cellulases with higher thermostability - Google Patents

modified cellulases with higher thermostability

Info

Publication number
BR112012031295A2
BR112012031295A2 BR112012031295A BR112012031295A BR112012031295A2 BR 112012031295 A2 BR112012031295 A2 BR 112012031295A2 BR 112012031295 A BR112012031295 A BR 112012031295A BR 112012031295 A BR112012031295 A BR 112012031295A BR 112012031295 A2 BR112012031295 A2 BR 112012031295A2
Authority
BR
Brazil
Prior art keywords
higher thermostability
modified
cellulases
modified cellulases
family
Prior art date
Application number
BR112012031295A
Other languages
Portuguese (pt)
Inventor
Edward Bayer
Michael Anbar
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of BR112012031295A2 publication Critical patent/BR112012031295A2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01004—Cellulase (3.2.1.4), i.e. endo-1,4-beta-glucanase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Paper (AREA)

Abstract

celulases modificadas com uma maior termoestabilidade. a presente invenção se refere acelulares da família 8 modifidadas que apresentam uma maior termoestabilidade em comparação com a enzima do tipo selvagem correspondente, a polinucleotídeos que codificam as celulases modificadas, a composições que compreendem as mesmas e aos seus usos. as variantes das celulares da família 8 apresentam vantagens para o processo de bioconversão de substratos celulósicos.modified cellulases with higher thermostability. The present invention relates to modified family 8 acellulars which exhibit higher thermostability compared to the corresponding wild-type enzyme, polynucleotides encoding modified cellulases, compositions comprising them and their uses. Family 8 cell phone variants have advantages for the bioconversion process of cellulosic substrates.

BR112012031295A 2010-06-07 2011-06-06 modified cellulases with higher thermostability BR112012031295A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35195110P 2010-06-07 2010-06-07
US201161473825P 2011-04-11 2011-04-11
PCT/IL2011/000447 WO2011154943A1 (en) 2010-06-07 2011-06-06 Modified cellulases with enhanced thermostability

Publications (1)

Publication Number Publication Date
BR112012031295A2 true BR112012031295A2 (en) 2016-02-16

Family

ID=44454679

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012031295A BR112012031295A2 (en) 2010-06-07 2011-06-06 modified cellulases with higher thermostability

Country Status (3)

Country Link
EP (1) EP2576775A1 (en)
BR (1) BR112012031295A2 (en)
WO (1) WO2011154943A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9035830B2 (en) 2012-09-28 2015-05-19 Nokia Technologies Oy Antenna arrangement

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
GB9724270D0 (en) 1997-11-17 1998-01-14 Babraham The Inst Methods and means for mutagenesis of dna
US20090130718A1 (en) 1999-02-04 2009-05-21 Diversa Corporation Gene site saturation mutagenesis
WO2003002761A1 (en) 2001-06-29 2003-01-09 Novozymes A/S Method of multimerization and site-directed mutagenesis
US7785854B2 (en) * 2006-08-31 2010-08-31 Iogen Energy Corporation Modified cellulases with increased thermostability, thermophilicity, and alkalophilicity
EP2443139B1 (en) * 2009-06-16 2016-08-10 Codexis, Inc. Beta-glucosidase variant enzymes and related polynucleotides

Also Published As

Publication number Publication date
EP2576775A1 (en) 2013-04-10
WO2011154943A1 (en) 2011-12-15

Similar Documents

Publication Publication Date Title
BR112012020277A2 (en) "optimized cellulase enzymes".
MX2010010144A (en) Hemicellulase enriched compositions for enhancing hydrolysis of biomass.
BR112012011711A2 (en) Beta-glucosidase 1 (bgl1) variants with optimized properties, their production method, composition, nucleic acid, expression vector, host cell, as well as method of converting biomass to sugars
BR112013025753A8 (en) METHODS FOR IMPROVING PRODUCT AND PRODUCTION YIELD IN A MICROORGANISM BY ADDITION OF ALTERNATIVE ELECTRON ACCEPTERS
BR112015013129A2 (en) methods and materials for biosynthesis of mogroside compounds
BR112013031414A2 (en) methods for converting lignocellulosic material into useful products
BR112014006009A8 (en) ENZYME VARIANTS WITH IMPROVED PROPERTIES
BR112016002067A2 (en) ENZYME VARIANTS
BR112013010812A2 (en) compositions and methods for producing fermentable sugars.
BR112013031307A2 (en) methods for treating lignocellulosic material
BR112015010134A2 (en) PROCESS FOR CONSUMPTION OF ACETATE DURING THE ETHANOL FERMENTATION OF CELLULOSIC RAW MATERIALS
MX342388B (en) Variants and compositions comprising variants with high stability in presence of a chelating agent.
AR069168A1 (en) ALFA VARIANTS -AMILASES WITH ALTERED PROPERTIES
MX353237B (en) Novel glycosyl hydrolase enzymes and uses thereof.
BR112013013136A2 (en) biogas production process
BR112013010551A8 (en) Isoprene synthase variants for enhanced isoprene production
EA201201125A1 (en) CELL-HOST, THE ABLE TO PRODUCT ENZYMES SUITABLE FOR DEGRADATION OF LIGNOCELLULOSE MATERIAL
WO2011143632A3 (en) Cellobiohydrolase variants
BR112015005782A2 (en) Enzyme variants with enhanced ester synthase properties
BR112013032092A2 (en) process for digestion of organic material
BR112014014151A2 (en) fungal cells and fermentation processes
BR112013009532A2 (en) thermostable tricoderma cellulase
IN2012DE00622A (en)
WO2013141905A3 (en) Engineering an increase in ethanol production by altering cofactor specificity
BR112013004419A2 (en) filamentous fungi that have a phenotype of altered viscosity.

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]