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BR0313100A - Immunogenic composition, isolated immunogenic composition, vaccine, method of treating or preventing gram-negative bacterial disease, use of the vaccine, genetically engineered gram-negative bacterial strain, method of preparing the immunogenic composition, method of preparing the vaccine, method of preparing a immunoglobulin for use in the prevention or treatment of neisserial infection, immunoglobulin preparation, pharmaceutical preparation, and use of pharmaceutical preparation - Google Patents

Immunogenic composition, isolated immunogenic composition, vaccine, method of treating or preventing gram-negative bacterial disease, use of the vaccine, genetically engineered gram-negative bacterial strain, method of preparing the immunogenic composition, method of preparing the vaccine, method of preparing a immunoglobulin for use in the prevention or treatment of neisserial infection, immunoglobulin preparation, pharmaceutical preparation, and use of pharmaceutical preparation

Info

Publication number
BR0313100A
BR0313100A BR0313100-9A BR0313100A BR0313100A BR 0313100 A BR0313100 A BR 0313100A BR 0313100 A BR0313100 A BR 0313100A BR 0313100 A BR0313100 A BR 0313100A
Authority
BR
Brazil
Prior art keywords
vaccine
immunogenic composition
preparing
preparation
immunoglobulin
Prior art date
Application number
BR0313100-9A
Other languages
Portuguese (pt)
Inventor
Francois-Xavier Jacque Berthet
Ralph Biemans
Philippe Denoel
Christiane Feron
Carine Goraj
Jan Poolman
Vincent Weynants
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0218051A external-priority patent/GB0218051D0/en
Priority claimed from GB0218037A external-priority patent/GB0218037D0/en
Priority claimed from GB0218035A external-priority patent/GB0218035D0/en
Priority claimed from GB0218036A external-priority patent/GB0218036D0/en
Priority claimed from GBGB0220199.4A external-priority patent/GB0220199D0/en
Priority claimed from GBGB0220197.8A external-priority patent/GB0220197D0/en
Priority claimed from GB0225531A external-priority patent/GB0225531D0/en
Priority claimed from GB0225524A external-priority patent/GB0225524D0/en
Priority claimed from GB0230164A external-priority patent/GB0230164D0/en
Priority claimed from GB0230168A external-priority patent/GB0230168D0/en
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Priority claimed from PCT/EP2003/008567 external-priority patent/WO2004014419A1/en
Publication of BR0313100A publication Critical patent/BR0313100A/en

Links

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

"COMPOSIçãO IMUNOGêNICA, COMPOSIçãO IMUNOGêNICA ISOLADA, VACINA, MéTODO DE TRATAMENTO OU PREVENçãO DE DOENçA BACTERIANA GRAM-NEGATIVA, USO DA VACINA, CEPA BACTERIANA GRAM-NEGATIVA GENETICAMENTE MANIPULADA, MéTODO PARA PREPARAR A COMPOSIçãO IMUNOGêNICA, MéTODO PARA PREPARAR A VACINA, MéTODO DE PREPARAR UMA IMUNOGLOBULINA PARA USO NA PREVENçãO OU TRATAMENTO DE INFECçãO NEISSERIAL, PREPARAçãO DE IMUNOGLOBULINA, PREPARAçãO FARMACêUTICA, E, USO DA PREPARAçãO FARMACêUTICA". A presente invenção refere-se a vacinas e composições imunogênicas para a prevenção ou tratamento de infecção bacteriana Gram-negativa. Demonstrou-se que composições imunogênicas da invenção compreendem proteína de ligação de transferina e Hsf, e a combinação destes dois antígenos atua sinergicamente para produzir anticorpos com elevada atividade em um ensaio bactericida no soro. Esta combinação de antígenos é útil para uso em vacinas contra Neisseria meningitidis, Neisseria gonorrhoeae, Moraxella catarrhalis e Haemophilus influenzae."IMMUNOGENIC COMPOSITION, ISOLATED IMMUNOGENIC COMPOSITION, VACCINE, METHOD OF TREATMENT OR PREVENTION OF GRAM-NEGATIVE BACTERIAL DISEASE, GRAM-NEGATIVE PREPARATION OF THE BACTERIAL PREPARATION OF THE PREPARATION OF THE PREPARATION OF THE PREPARATION IMMUNOGLOBULIN FOR USE IN PREVENTION OR TREATMENT OF NEISSERIAL INFECTION, PREPARATION OF IMMUNOGLOBULIN, PHARMACEUTICAL PREPARATION, AND USE OF PHARMACEUTICAL PREPARATION ". The present invention relates to vaccines and immunogenic compositions for the prevention or treatment of Gram-negative bacterial infection. Immunogenic compositions of the invention have been shown to comprise transferin binding protein and Hsf, and the combination of these two antigens acts synergistically to produce antibodies with high activity in a serum bactericidal assay. This combination of antigens is useful for use in vaccines against Neisseria meningitidis, Neisseria gonorrhoeae, Moraxella catarrhalis and Haemophilus influenzae.

BR0313100-9A 2002-08-02 2003-07-31 Immunogenic composition, isolated immunogenic composition, vaccine, method of treating or preventing gram-negative bacterial disease, use of the vaccine, genetically engineered gram-negative bacterial strain, method of preparing the immunogenic composition, method of preparing the vaccine, method of preparing a immunoglobulin for use in the prevention or treatment of neisserial infection, immunoglobulin preparation, pharmaceutical preparation, and use of pharmaceutical preparation BR0313100A (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
GB0218035A GB0218035D0 (en) 2002-08-02 2002-08-02 Vaccine composition
GB0218036A GB0218036D0 (en) 2002-08-02 2002-08-02 Vaccine
GB0218051A GB0218051D0 (en) 2002-08-02 2002-08-02 Vaccine composition
GB0218037A GB0218037D0 (en) 2002-08-02 2002-08-02 Vaccine composition
GBGB0220199.4A GB0220199D0 (en) 2002-08-30 2002-08-30 Mutant protein and refolding method
GBGB0220197.8A GB0220197D0 (en) 2002-08-30 2002-08-30 Refolding method
GB0225531A GB0225531D0 (en) 2002-11-01 2002-11-01 Vaccine
GB0225524A GB0225524D0 (en) 2002-11-01 2002-11-01 Vaccine composition
GB0230164A GB0230164D0 (en) 2002-12-24 2002-12-24 Vaccine composition
GB0230168A GB0230168D0 (en) 2002-12-24 2002-12-24 Vaccine composition
PCT/EP2003/008567 WO2004014419A1 (en) 2002-08-02 2003-07-31 Vaccine composition comprising transferrin binding protein and hsf from gram negative bacteria

Publications (1)

Publication Number Publication Date
BR0313100A true BR0313100A (en) 2005-06-21

Family

ID=34705473

Family Applications (2)

Application Number Title Priority Date Filing Date
BR0313100-9A BR0313100A (en) 2002-08-02 2003-07-31 Immunogenic composition, isolated immunogenic composition, vaccine, method of treating or preventing gram-negative bacterial disease, use of the vaccine, genetically engineered gram-negative bacterial strain, method of preparing the immunogenic composition, method of preparing the vaccine, method of preparing a immunoglobulin for use in the prevention or treatment of neisserial infection, immunoglobulin preparation, pharmaceutical preparation, and use of pharmaceutical preparation
BRPI0313120-3A BR0313120A (en) 2002-08-02 2003-07-31 bleb and de los preparations, neisserial / neisserial strain (s), immunogenic composition or vaccine, and, manufacturing processes of the neisserial bleb preparation vaccine and production of a bleb preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0313120-3A BR0313120A (en) 2002-08-02 2003-07-31 bleb and de los preparations, neisserial / neisserial strain (s), immunogenic composition or vaccine, and, manufacturing processes of the neisserial bleb preparation vaccine and production of a bleb preparation

Country Status (2)

Country Link
CN (1) CN103007263A (en)
BR (2) BR0313100A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107722120B (en) * 2017-08-29 2020-07-14 杭州医学院 A kind of serum for treating otitis media caused by Haemophilus influenzae and application of the serum
CN107602697B (en) * 2017-08-29 2020-05-05 杭州医学院 Serum for treating nasosinusitis caused by haemophilus influenzae and application of serum

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9726398D0 (en) * 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
EP2270174A1 (en) * 1999-05-19 2011-01-05 Novartis Vaccines and Diagnostics S.r.l. Combination neisserial compositions
GB9918319D0 (en) * 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition

Also Published As

Publication number Publication date
BR0313120A (en) 2007-07-17
CN103007263A (en) 2013-04-03

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2317 DE 02-06-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI