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BR0307671A - Derivados de tricicloimidazolina, método para sua produção e uso dos mesmos como medicamentos - Google Patents

Derivados de tricicloimidazolina, método para sua produção e uso dos mesmos como medicamentos

Info

Publication number
BR0307671A
BR0307671A BR0307671-7A BR0307671A BR0307671A BR 0307671 A BR0307671 A BR 0307671A BR 0307671 A BR0307671 A BR 0307671A BR 0307671 A BR0307671 A BR 0307671A
Authority
BR
Brazil
Prior art keywords
sub
tricycloimidazoline
medicines
derivatives
production
Prior art date
Application number
BR0307671-7A
Other languages
English (en)
Inventor
Bernard Vacher
Bernard Bonnaud
Marc Marien
Thierry Imbert
Original Assignee
Pf Medicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pf Medicament filed Critical Pf Medicament
Publication of BR0307671A publication Critical patent/BR0307671A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C69/757—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"DERIVADOS DE TRICICLOIMIDAZOLINA, MéTODO PARA SUA PRODUçãO E USO DOS MESMOS COMO MEDICAMENTOS". A presente invenção refere-se a compostos de fórmula geral (1) em que R1 = H, F ou OCH~ 3~, e pode ocupar a posição 2, 3, 4 ou 5 no carbociclo aromático, R2 = H ou CH~ 3~, R3 = H, CH~ 3~, OH ou OCH~ 3~, R4 = H e R3 e R4 juntos podem ser um grupo carbonila (C=O), seus sais de adição e opcionalmente os hidratos de sais de adição com ácidos minerais ou orgânicos farmaceuticamente aceitáveis, seus isómeros e tautómeros.
BR0307671-7A 2002-02-14 2003-02-14 Derivados de tricicloimidazolina, método para sua produção e uso dos mesmos como medicamentos BR0307671A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0201839A FR2835834B1 (fr) 2002-02-14 2002-02-14 Nouveaux derives de tricyclo-imidazolines, leur procede de preparation et leur utilisation a titre de medicaments
PCT/FR2003/000480 WO2003068755A1 (fr) 2002-02-14 2003-02-14 Nouveaux derives de tricyclo-imidazolines, leur procede de preparation et leur utilisation a titre de medicaments

Publications (1)

Publication Number Publication Date
BR0307671A true BR0307671A (pt) 2005-01-04

Family

ID=27620209

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0307671-7A BR0307671A (pt) 2002-02-14 2003-02-14 Derivados de tricicloimidazolina, método para sua produção e uso dos mesmos como medicamentos

Country Status (13)

Country Link
US (1) US20050107455A1 (pt)
EP (1) EP1476433B1 (pt)
JP (1) JP2005525342A (pt)
CN (1) CN1646496A (pt)
AT (1) ATE309221T1 (pt)
AU (1) AU2003226482A1 (pt)
BR (1) BR0307671A (pt)
CA (1) CA2475880A1 (pt)
DE (1) DE60302217D1 (pt)
FR (1) FR2835834B1 (pt)
MX (1) MXPA04007856A (pt)
WO (1) WO2003068755A1 (pt)
ZA (1) ZA200406445B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2323734A1 (en) * 2008-08-04 2011-05-25 Schering Corporation Cyclopropylchromene derivatives as modulators of the alpha-2c receptor
CN103360360A (zh) * 2012-04-10 2013-10-23 肖竹平 一种基于二氢杨梅素制备(+)-没食子儿茶素的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1280779E (pt) * 2000-05-08 2005-11-30 Orion Corp Novos indanilimidazois policiclicos com actividade adrenergica alfa2

Also Published As

Publication number Publication date
CA2475880A1 (fr) 2003-08-21
DE60302217D1 (de) 2005-12-15
MXPA04007856A (es) 2004-10-15
US20050107455A1 (en) 2005-05-19
EP1476433A1 (fr) 2004-11-17
JP2005525342A (ja) 2005-08-25
AU2003226482A1 (en) 2003-09-04
FR2835834B1 (fr) 2004-04-02
ZA200406445B (en) 2005-06-14
FR2835834A1 (fr) 2003-08-15
CN1646496A (zh) 2005-07-27
ATE309221T1 (de) 2005-11-15
WO2003068755A1 (fr) 2003-08-21
EP1476433B1 (fr) 2005-11-09

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Legal Events

Date Code Title Description
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]