[go: up one dir, main page]

BR0208879A - Artigo - Google Patents

Artigo

Info

Publication number
BR0208879A
BR0208879A BR0208879-7A BR0208879A BR0208879A BR 0208879 A BR0208879 A BR 0208879A BR 0208879 A BR0208879 A BR 0208879A BR 0208879 A BR0208879 A BR 0208879A
Authority
BR
Brazil
Prior art keywords
cells
present
article
layer
support matrices
Prior art date
Application number
BR0208879-7A
Other languages
English (en)
Inventor
Bruno M Giannetti
Samuel S Asculai
Ahmed Idouraine
Original Assignee
Verigen Transplantation Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verigen Transplantation Serv filed Critical Verigen Transplantation Serv
Publication of BR0208879A publication Critical patent/BR0208879A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3817Cartilage-forming cells, e.g. pre-chondrocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30756Cartilage endoprostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3629Intestinal tissue, e.g. small intestinal submucosa
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645Connective tissue
    • A61L27/3654Cartilage, e.g. meniscus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843Connective tissue
    • A61L27/3852Cartilage, e.g. meniscus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068General culture methods using substrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0655Chondrocytes; Cartilage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/54Collagen; Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"ARTIGO". A presente invenção descreve várias matrizes de suporte, em que as células podem aderir e proliferar. Tais matrizes de suporte são úteis para implante em um sítio ferido, para promover a cura e regeneração do tecido avariado. O presente ainda descreve um artigo incluindo uma membrana tendo pelo menos uma camada tendo uma superfície porosa e também incluindo tecido de intestino submucoso e células aderidas à camada. A presente invenção descreve ainda que as células aderidas à camada incluem células de condrócito.
BR0208879-7A 2001-04-12 2002-04-12 Artigo BR0208879A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28325301P 2001-04-12 2001-04-12
PCT/US2002/011497 WO2002083878A1 (en) 2001-04-12 2002-04-12 Method for autologous transplantation

Publications (1)

Publication Number Publication Date
BR0208879A true BR0208879A (pt) 2004-06-29

Family

ID=23085209

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0208879-7A BR0208879A (pt) 2001-04-12 2002-04-12 Artigo

Country Status (14)

Country Link
EP (1) EP1390471A4 (pt)
JP (1) JP2005502390A (pt)
CN (1) CN1514877A (pt)
BR (1) BR0208879A (pt)
CA (1) CA2444004A1 (pt)
CZ (1) CZ20033051A3 (pt)
HU (1) HUP0401450A3 (pt)
IL (1) IL158371A0 (pt)
MX (1) MXPA03009312A (pt)
NO (1) NO20034581L (pt)
PL (1) PL367295A1 (pt)
RU (1) RU2003132877A (pt)
SK (1) SK13892003A3 (pt)
WO (1) WO2002083878A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005221083A1 (en) * 2004-03-09 2005-09-22 Osteobiologics, Inc. Implant scaffold combined with autologous or allogenic tissue
US20060100138A1 (en) * 2004-11-10 2006-05-11 Olsen David R Implantable collagen compositions
DE102005030614B4 (de) 2005-06-30 2014-05-08 Biotissue Ag Zellfreies Transplantat, dessen Verwendung, Verfahren zu dessen Herstellung, dabei hergestellte Matrix mit Gel und Verfahren zur Herstellung dieser Matrix mit Gel
JP5225844B2 (ja) * 2005-09-02 2013-07-03 エー・デー・ガイストリヒ・ゾーネ・アクチェンゲゼルシャフト・フュール・ヒェーミシェ・インダストリー 半月板断裂を修復するためのコラーゲン膜材料のシート
CA2713118A1 (en) * 2008-02-29 2009-09-03 Interface Biotech A/S Biosynthetic cartilaginous matrix and methods for their production
EP2698173A1 (en) 2008-02-29 2014-02-19 Coloplast A/S Compositions and methods for augmentation and regeneration of living tissue in a subject
CA2878808A1 (en) * 2012-07-11 2014-01-16 Osiris Therapeutics, Inc. Methods of manufacturing cartilage products

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5788625A (en) * 1996-04-05 1998-08-04 Depuy Orthopaedics, Inc. Method of making reconstructive SIS structure for cartilaginous elements in situ
US5759190A (en) * 1996-08-30 1998-06-02 Vts Holdings Limited Method and kit for autologous transplantation
US6171340B1 (en) * 1998-02-27 2001-01-09 Mcdowell Charles L. Method and device for regenerating cartilage in articulating joints

Also Published As

Publication number Publication date
CN1514877A (zh) 2004-07-21
IL158371A0 (en) 2004-05-12
HUP0401450A3 (en) 2006-11-28
NO20034581D0 (no) 2003-10-10
EP1390471A4 (en) 2005-04-13
HUP0401450A2 (hu) 2004-11-29
EP1390471A1 (en) 2004-02-25
MXPA03009312A (es) 2004-03-10
CZ20033051A3 (en) 2004-05-12
CA2444004A1 (en) 2002-10-24
SK13892003A3 (sk) 2004-07-07
WO2002083878A1 (en) 2002-10-24
PL367295A1 (en) 2005-02-21
NO20034581L (no) 2003-12-09
JP2005502390A (ja) 2005-01-27
RU2003132877A (ru) 2005-03-10

Similar Documents

Publication Publication Date Title
BR0207775A (pt) Lipossomos anfotéricos métodos para carregamento dos mesmos com ingredientes ativos e sua utilização
ES2150492T3 (es) Utilizacion de un material poroso a base de carbonato de calcio como soporte para un factor de crecimiento en la preparacion de un implante.
ES2152196T3 (es) Implante para vertebra.
BR9912517A (pt) Membranas compósitas e métodos para fabricação de tais membranas
AR004357A1 (es) Compuestos de 1-fenil-2-dimetilaminometil-ciclohexan-1-ol, y procedimiento de preparacion para dichos compuestos.
BR0107942A (pt) Polìmeros de proteìna de liberação lenta
BR0203650A (pt) Estentor de auto-articulação
ATE214595T1 (de) Verfahren zur herstellung von lösungsmittelfreien nicht-kristallinen biologisch aktiven substanzen
SE9604793D0 (sv) New polymorphs
ECSP045520A (es) Metodos de tratamiento con inhibidores de la ptec y agentes antihipertensivos
ES2195664T3 (es) Uso de fumaratos de dialquilo.
AR024138A1 (es) Inhibidores de la proliferacion celular
DK1715900T3 (da) Kompositstrukturer, som indeholder hyaluronsyre derivaterne deraf som nye knoglesubstitutter og -transplantater
ATE224213T1 (de) Implantat aus resorbierbaren phosphatglas
BR0211257A (pt) Aparelho para enxerto de um vaso sanguìneo, enxerto para um vaso sanguìneo, e, métodos para formação de um enxerto para inserção em um vaso sanguìneo e para preparo de um emplastro para inserção em um vaso sanguìneo
TR199900310T2 (xx) Trombin inhibit�rleri
IS5856A (is) Aðferðir þar sem integrín-mótlyf eru notuð til aðmeðhöndla margföld mergæxli og uppsog í bein af völdum mergæxla
BR0208879A (pt) Artigo
ATE361756T1 (de) Insulinartiger-wachstumsfaktorbindungsprotein-4 protease
PT1017681E (pt) Derivados de hidrazono-benzazuleno composicoes farmaceuticas e intermediarios
ATE414267T1 (de) Gewebefixativzusammensetzung
DE69026087D1 (de) Substituierte 2-imidazoline und verfahren zur herstellung sowie deren verwendung
BR0116641A (pt) Uso de um material biológico contendo armações tridimensionais de derivados de ácido hialurÈnico para preparação de implantes por artroscopia e kit de instrumentos para inserção do dito material biológico por artrocospia
PT1185314E (pt) Material para um enxerto osseo feito de uma ceramica fosfocalcica e de tecido osseo
BR0309008A (pt) polipeptìdeos de micoplasma

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 6A., 7A. E 8A. ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2060 DE 29/06/2010.