[go: up one dir, main page]

BR0013375A - Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation - Google Patents

Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation

Info

Publication number
BR0013375A
BR0013375A BR0013375-2A BR0013375A BR0013375A BR 0013375 A BR0013375 A BR 0013375A BR 0013375 A BR0013375 A BR 0013375A BR 0013375 A BR0013375 A BR 0013375A
Authority
BR
Brazil
Prior art keywords
composition
preparation
compositions containing
pharmaceutical compositions
pharmaceutically acceptable
Prior art date
Application number
BR0013375-2A
Other languages
Portuguese (pt)
Inventor
Robin Edwin Buckingham
Michael Urquhart
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9919465.6A external-priority patent/GB9919465D0/en
Priority claimed from GBGB9919842.6A external-priority patent/GB9919842D0/en
Priority claimed from GBGB9920149.3A external-priority patent/GB9920149D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of BR0013375A publication Critical patent/BR0013375A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"COMPOSIçõES FARMACêUTICAS CONTENDO DERIVADOS TIAZOLIDINODIONA E PROCESSO PARA SUA PREPARAçãO". Uma composição farmacêutica, cuja composição compreende uma quantidade eficaz, não tóxica, de um composto de fórmula (I), ou uma sua forma tautomérica e/ou um seu sal farmaceuticamente aceitável, e/ou um seu solvato farmaceuticamente aceitável, onde: A^ 1^ representa OH ou -OSO~ 2~OH; R^ 1^ representa um átomo de hidrogênio ou um grupo alquila C~ 1-6~; e R^ 2^ e R^ 3^ cada um representa hidrogênio ou R^ 2^ e R^ 3^ juntos representam uma ligação; e um veículo farmaceuticamente aceitável para isso; alguns novos compostos usados em tal composição e o uso de tais compostos e da composição em medicina."Pharmaceutical compositions containing thiazolidine derivatives and process for their preparation". A pharmaceutical composition, the composition of which comprises a non-toxic effective amount of a compound of formula (I), or a tautomeric form thereof and / or a pharmaceutically acceptable salt thereof, and / or a pharmaceutically acceptable solvate thereof, wherein: R1 represents OH or -OSO-2-OH; R 13 represents a hydrogen atom or a C 1-6 alkyl group; and R 2 and R 3 each represent hydrogen or R 2 and R 3 together represent a bond; and a pharmaceutically acceptable carrier therefor; some novel compounds used in such a composition and the use of such compounds and the composition in medicine.

BR0013375-2A 1999-08-17 2000-08-14 Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation BR0013375A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9919465.6A GB9919465D0 (en) 1999-08-17 1999-08-17 Novel compounds
GBGB9919842.6A GB9919842D0 (en) 1999-08-20 1999-08-20 Novel compounds
GBGB9920149.3A GB9920149D0 (en) 1999-08-25 1999-08-25 Novel compounds
PCT/EP2000/007926 WO2001012628A1 (en) 1999-08-17 2000-08-14 Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
BR0013375A true BR0013375A (en) 2002-07-23

Family

ID=27269792

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0013375-2A BR0013375A (en) 1999-08-17 2000-08-14 Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation

Country Status (15)

Country Link
EP (1) EP1202991A1 (en)
JP (1) JP2003507379A (en)
KR (1) KR20020022812A (en)
CN (1) CN1379776A (en)
AU (1) AU7408900A (en)
BR (1) BR0013375A (en)
CA (1) CA2381976A1 (en)
CZ (1) CZ2002531A3 (en)
HU (1) HUP0202438A2 (en)
IL (1) IL148164A0 (en)
MX (1) MXPA02001716A (en)
NO (1) NO20020777L (en)
PL (1) PL353886A1 (en)
TR (1) TR200200438T2 (en)
WO (1) WO2001012628A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001260615A1 (en) * 2000-05-25 2001-12-03 Yamanouchi Pharmaceutical Co..Ltd. Human pgc-1 promoter
WO2003029251A1 (en) * 2001-09-28 2003-04-10 Biocon Limited Novel process for the synthesis of thiazolidinedione derivatives
GB0129871D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
GB0130509D0 (en) * 2001-12-20 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
KR100450700B1 (en) * 2002-03-22 2004-10-01 주식회사종근당 Thiazolidinedione derivatives and pharmaceutical composition comprising the same
KR20050068860A (en) 2003-12-30 2005-07-05 엘지.필립스 엘시디 주식회사 Upper substrate for use in dual-plate organic electroluminescent device and method for fabricating the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE186724T1 (en) * 1987-09-04 1999-12-15 Beecham Group Plc SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVES
GB8919417D0 (en) * 1989-08-25 1989-10-11 Beecham Group Plc Novel compounds
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
WO1995021608A1 (en) * 1994-02-10 1995-08-17 Smithkline Beecham Plc Use of insulin sensitisers for treating renal diseases

Also Published As

Publication number Publication date
JP2003507379A (en) 2003-02-25
IL148164A0 (en) 2002-09-12
NO20020777D0 (en) 2002-02-15
MXPA02001716A (en) 2002-08-06
HUP0202438A2 (en) 2002-12-28
TR200200438T2 (en) 2002-05-21
NO20020777L (en) 2002-02-15
WO2001012628A1 (en) 2001-02-22
CN1379776A (en) 2002-11-13
PL353886A1 (en) 2003-12-01
KR20020022812A (en) 2002-03-27
CZ2002531A3 (en) 2002-07-17
AU7408900A (en) 2001-03-13
CA2381976A1 (en) 2001-02-22
EP1202991A1 (en) 2002-05-08

Similar Documents

Publication Publication Date Title
HUP0102554A1 (en) Benzothiepine-1,1-dioxide derivatives, method for producing them, medicaments containing these compounds and their use
EE200100558A (en) A triaryl acid derivative, a pharmaceutical composition comprising it, and a compound for therapeutic use
PL315636A1 (en) Cosmetic or pharmaceutic compositions containing magnipherine or its derivatives
MXPA02012034A (en) Thiophene derivatives useful as anticancer agents.
HUP0102453A2 (en) Adenosine derivatives, their use and pharmaceutical compositions containing the compounds
AU7517400A (en) N-substituted 4-aminopteridines, synthesis and use thereof as pharmaceutical agent
AP9801321A0 (en) 2-(4-aryl or heteroaryl-piperazin-1-ylmethyl)-h-indole derivatives.
HU895226D0 (en) Process for the preparation of novel imidazoline derivatives and pharmaceutical compositions containing said compounds as active ingredients
PT992509E (en) NEW MACROLIDED DERIVATIVES
BR0013375A (en) Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation
ATE81655T1 (en) CEPHEM COMPOUNDS AND PROCESSES FOR THEIR PRODUCTION.
AR018632A1 (en) COMPOUNDS DERIVED FROM ACID 1,2,3,4-TETRAHYDROQUINOLIN-2-CARBOXILICO, ITS USE IN THE MANUFACTURE OF MEDICINES, PHARMACEUTICAL COMPOSITION CONTAINING THEM, PROCESS FOR PREPARATION.
HK1026212A1 (en) New indian-1-ol compounds, a process for their preparation and pharmaceutical compositions containing them
NO20003106D0 (en) Acronycin compounds, their preparation, and pharmaceutical compositions comprising such
MY136694A (en) New thiadiazine compounds, a process for their preparation and pharmaceutical compositions containing them
DK558786D0 (en) BASIC SUBSTITUTED PYRIDINE COMPOUNDS, PREPARATION THEREOF, AND MEDICINES, CONTAINING THESE
DK0556813T3 (en) Amphoteric tricyclic compounds such as antihistamine and antiallergic agents
DK702788A (en) THIOFORMAMIDE DERIVATIVES AND PHARMACEUTICAL ACCEPTABLE SALTS THEREOF, THEIR PREPARATION AND USE
AU562024B2 (en) (hydroxypropyl) phenoxy (propyl) piperidine
YU29299A (en) Steroids substituted in position 11, method of preparation, application as medicines and pharmaceutical composition containing them
WO2000024389A3 (en) Benzoquinoline derivatives useful as antibacterial agents
HUP0002715A2 (en) Use of benzotiophen derivatives for production of pharmaceutical compositions for lowering platelet counts
ATE78032T1 (en) 2-PYRIDYLACETIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
ATE29133T1 (en) TROPONONE DERIVATIVES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITION CONTAINING THEM.
WO2000008006A3 (en) Piperidine and piperazine derivatives, process for their preparation and pharmaceutical compounds containing them

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A, 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1927 DE 11/12/2007.