BR0011815B1 - processo para a purificação de poloxámeros que contêm impurezas de aldeìdo. - Google Patents
processo para a purificação de poloxámeros que contêm impurezas de aldeìdo.Info
- Publication number
- BR0011815B1 BR0011815B1 BRPI0011815-0A BR0011815A BR0011815B1 BR 0011815 B1 BR0011815 B1 BR 0011815B1 BR 0011815 A BR0011815 A BR 0011815A BR 0011815 B1 BR0011815 B1 BR 0011815B1
- Authority
- BR
- Brazil
- Prior art keywords
- purification
- poloxamers
- poloxamer
- aldehyde impurities
- containing aldehyde
- Prior art date
Links
- 229920001983 poloxamer Polymers 0.000 title abstract 5
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000000746 purification Methods 0.000 title abstract 3
- 239000012535 impurity Substances 0.000 title abstract 2
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 4
- 239000002904 solvent Substances 0.000 abstract 3
- 229960000502 poloxamer Drugs 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001993 poloxamer 188 Polymers 0.000 abstract 1
- 229940044519 poloxamer 188 Drugs 0.000 abstract 1
- 229920001992 poloxamer 407 Polymers 0.000 abstract 1
- 229940044476 poloxamer 407 Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/30—Post-polymerisation treatment, e.g. recovery, purification, drying
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polyethers (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9902364A SE9902364D0 (sv) | 1999-06-21 | 1999-06-21 | New process |
| PCT/SE2000/001305 WO2000078841A1 (en) | 1999-06-21 | 2000-06-19 | New process for the purification of aldehyde impurities |
| US09/656,036 US6448371B1 (en) | 1999-06-21 | 2000-09-08 | Process for the purification of aldehyde impurities |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR0011815A BR0011815A (pt) | 2002-03-19 |
| BR0011815B1 true BR0011815B1 (pt) | 2010-06-15 |
Family
ID=26663601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0011815-0A BR0011815B1 (pt) | 1999-06-21 | 2000-06-19 | processo para a purificação de poloxámeros que contêm impurezas de aldeìdo. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6448371B1 (pt) |
| EP (1) | EP1192204B1 (pt) |
| JP (1) | JP2003503517A (pt) |
| CN (1) | CN1139615C (pt) |
| AT (1) | ATE312863T1 (pt) |
| AU (1) | AU765560B2 (pt) |
| BR (1) | BR0011815B1 (pt) |
| CA (1) | CA2377004A1 (pt) |
| DE (1) | DE60024821T2 (pt) |
| DK (1) | DK1192204T3 (pt) |
| ES (1) | ES2254200T3 (pt) |
| IL (1) | IL146746A0 (pt) |
| MX (1) | MXPA01013369A (pt) |
| NO (1) | NO318915B1 (pt) |
| NZ (1) | NZ515954A (pt) |
| SE (1) | SE9902364D0 (pt) |
| WO (1) | WO2000078841A1 (pt) |
| ZA (1) | ZA200109740B (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040266983A1 (en) * | 2000-08-17 | 2004-12-30 | Reeve Lorraine E | Purified polyoxyalkylene block copolymers |
| WO2002088217A1 (en) * | 2001-05-01 | 2002-11-07 | Union Carbide Chemicals & Plastics Technology Corporation | Poly(alkylene oxides) having reduced amounts of formic compounds |
| AU2003243172A1 (en) * | 2002-04-29 | 2003-11-17 | Alza Corporation | Reduced formate poly(alkylene oxides) with secondary amines for reducing impurity formation |
| JP2005343964A (ja) * | 2004-06-01 | 2005-12-15 | Otsuka Pharmaceut Factory Inc | ポリアルキレングリコール類含有水溶液、及びその調製方法 |
| KR101343040B1 (ko) * | 2010-12-28 | 2013-12-18 | 주식회사 삼양바이오팜 | 정제된 폴록사머 및 그의 정제방법 |
| JP2013237638A (ja) * | 2012-05-15 | 2013-11-28 | Lion Corp | 眼科組成物 |
| JP6747748B2 (ja) | 2014-07-07 | 2020-08-26 | ライフラフト バイオサイエンシーズ，インコーポレイテッド | 長期循環物質のないポロクサマー組成物、その産生方法およびその使用 |
| BR112018012678B1 (pt) | 2015-12-22 | 2022-03-08 | Basf Se | Processo para purificação de copolímeros em bloco de poliéter. |
| JP6634531B2 (ja) * | 2017-01-06 | 2020-01-22 | 三洋化成工業株式会社 | ポリエーテルポリオールの製造方法及びポリウレタンフォームの製造方法 |
| JP2020506276A (ja) * | 2017-02-09 | 2020-02-27 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | ポリエーテルブロックコポリマーの精製方法 |
| KR20200100108A (ko) | 2017-12-20 | 2020-08-25 | 바스프 에스이 | 양친매성 그라프트 공중합체를 세포 배양 시약으로 이용하여 세포 배양 시스템을 안정화하는 방법 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3036130A (en) * | 1957-09-10 | 1962-05-22 | Wyandotte Chemicals Corp | Mixtures of novel conjugated polyoxyethylene-polyoxypropylene compounds |
| US3462379A (en) * | 1965-12-02 | 1969-08-19 | Dow Chemical Co | Purification of poly(alkylene oxides) |
| US3546321A (en) * | 1967-02-08 | 1970-12-08 | Hercules Inc | Polyether graft copolymers |
| US3639574A (en) * | 1967-10-25 | 1972-02-01 | Basf Wyandotte Corp | Stable hydrogen peroxide gels |
| US3715402A (en) * | 1969-08-08 | 1973-02-06 | Basf Wyandotte Corp | Removal of catalysts from polyols |
| US3674502A (en) * | 1969-09-05 | 1972-07-04 | Firmenich Inc | Nonringing beverages containing poly(oxyethylene) - poly(oxypropylene) - poly(oxyethylene) copolymers |
| DE2755089C3 (de) * | 1977-12-10 | 1982-05-13 | Bayer Ag, 5090 Leverkusen | Verfahren zur Reinigung von Rohpolyäthern |
| DE2854541A1 (de) * | 1978-12-16 | 1980-06-26 | Bayer Ag | Verfahren zur reinigung nichtionischer emulgatoren |
| US4410447A (en) * | 1980-11-12 | 1983-10-18 | Union Carbide Corporation | Low-foaming nonionic surfactants |
| US4606918A (en) * | 1983-08-22 | 1986-08-19 | Syntex (U.S.A.) Inc. | Polyoxypropylene-polyoxyethylene block polymer based adjuvants |
| US5342541A (en) * | 1989-03-29 | 1994-08-30 | The Dow Chemical Company | Purified hydroxy-functional polyether compounds |
| DE3913937A1 (de) * | 1989-04-27 | 1990-10-31 | Hoechst Ag | Verfahren zur reinigung von alkylenoxid-addukten |
| JPH0791389B2 (ja) * | 1989-05-17 | 1995-10-04 | 信越化学工業株式会社 | 精製されたポリエーテルシリコーン及びその製造方法 |
| US5095061A (en) * | 1990-07-13 | 1992-03-10 | The Dow Chemical Company | Process to reduce propenyl polyethers in hydroxyfunctional polyethers |
| US5268510A (en) * | 1992-10-08 | 1993-12-07 | Vista Chemical Company | Process for purification of alkoxylated alcohols |
| KR0145350B1 (ko) * | 1993-09-07 | 1998-07-15 | 사또오 아키오 | 폴리옥시알킬렌폴리올의 제조방법 |
| CA2174394A1 (en) * | 1995-06-12 | 1996-12-13 | Timothy L. Lambert | Process for preparing low unsaturation polyether polyols |
| US6166266A (en) * | 1998-11-12 | 2000-12-26 | Bp Amoco Corporation | Preparation of polyoxymethylene dimethyl ethers by catalytic conversion of dimethyl ether with formaldehyde formed by oxidation of methanol |
-
1999
- 1999-06-21 SE SE9902364A patent/SE9902364D0/xx unknown
-
2000
- 2000-06-19 AT AT00946611T patent/ATE312863T1/de not_active IP Right Cessation
- 2000-06-19 DE DE60024821T patent/DE60024821T2/de not_active Expired - Lifetime
- 2000-06-19 CN CNB008093067A patent/CN1139615C/zh not_active Expired - Lifetime
- 2000-06-19 NZ NZ515954A patent/NZ515954A/en not_active IP Right Cessation
- 2000-06-19 ES ES00946611T patent/ES2254200T3/es not_active Expired - Lifetime
- 2000-06-19 AU AU60343/00A patent/AU765560B2/en not_active Expired
- 2000-06-19 CA CA002377004A patent/CA2377004A1/en not_active Abandoned
- 2000-06-19 WO PCT/SE2000/001305 patent/WO2000078841A1/en active IP Right Grant
- 2000-06-19 EP EP00946611A patent/EP1192204B1/en not_active Expired - Lifetime
- 2000-06-19 MX MXPA01013369A patent/MXPA01013369A/es active IP Right Grant
- 2000-06-19 IL IL14674600A patent/IL146746A0/xx active IP Right Grant
- 2000-06-19 DK DK00946611T patent/DK1192204T3/da active
- 2000-06-19 JP JP2001505595A patent/JP2003503517A/ja active Pending
- 2000-06-19 BR BRPI0011815-0A patent/BR0011815B1/pt not_active IP Right Cessation
- 2000-09-08 US US09/656,036 patent/US6448371B1/en not_active Expired - Lifetime
-
2001
- 2001-11-27 ZA ZA200109740A patent/ZA200109740B/en unknown
- 2001-12-20 NO NO20016297A patent/NO318915B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200109740B (en) | 2003-03-03 |
| SE9902364D0 (sv) | 1999-06-21 |
| JP2003503517A (ja) | 2003-01-28 |
| AU6034300A (en) | 2001-01-09 |
| DE60024821D1 (de) | 2006-01-19 |
| NO20016297L (no) | 2002-02-04 |
| DE60024821T2 (de) | 2006-06-14 |
| WO2000078841A1 (en) | 2000-12-28 |
| NO20016297D0 (no) | 2001-12-20 |
| CN1357019A (zh) | 2002-07-03 |
| ATE312863T1 (de) | 2005-12-15 |
| US6448371B1 (en) | 2002-09-10 |
| EP1192204A1 (en) | 2002-04-03 |
| EP1192204B1 (en) | 2005-12-14 |
| MXPA01013369A (es) | 2002-07-30 |
| ES2254200T3 (es) | 2006-06-16 |
| CN1139615C (zh) | 2004-02-25 |
| CA2377004A1 (en) | 2000-12-28 |
| IL146746A0 (en) | 2002-07-25 |
| NO318915B1 (no) | 2005-05-23 |
| DK1192204T3 (da) | 2006-02-20 |
| BR0011815A (pt) | 2002-03-19 |
| AU765560B2 (en) | 2003-09-25 |
| NZ515954A (en) | 2003-05-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0011815B1 (pt) | processo para a purificação de poloxámeros que contêm impurezas de aldeìdo. | |
| ATE365340T1 (de) | Zur bilderzeugung mit tiefer uv-strahlung geeignete photoresistzusammensetzung und diese verwendendes bilderzeugungsverfahren | |
| BR0213380A (pt) | Derivados propiÈnicos alfa-oxissubstituìdos por beta-fenila: processo para sua preparação e seu uso na preparação de compostos farmaceuticamente importantes | |
| NO20071498L (no) | Substituerte acylhydroksamsyrer samt fremgangsmate for a redusere TNFa-nivaet | |
| NO20013881D0 (no) | Fremstilling av iodixanol | |
| DE59010254D1 (de) | Chinoloncarbonsäurederivate, Verfahren zu ihrer Herstellung sowie ihre Verwendung als antivirale Mittel | |
| BR0009129A (pt) | Processo e conjunto de exposição de uma imagemutilizando-se uma superfìcie adesiva reutilizável,e, compósito gráfico de imagem montaveladesivamente tendo uma superfìcie reutilizável | |
| BR0303658A (pt) | Inibidor de corrosão | |
| BR0210931A (pt) | Processo de preparação de micofenolato de mofetila | |
| ATE263145T1 (de) | Verfahren zur herstellung von n-carbamat- geschütztem beta-aminoepoxid und beta- aminoalkohol | |
| PT927195E (pt) | Processo para o fabrico de um medicamento contendo plasmoproteina | |
| AR046065A1 (es) | Cristales de penam y procedimiento para la produccion de los mismos | |
| BR0315254A (pt) | Processo para a fabricação de um composto, e, composto | |
| BR0208999A (pt) | Processo para a preparação de ácido de cefpodoxima | |
| ES2185551T3 (es) | Metodo de recuperar especies quimicas por despolimerizacion de poli(tereftalato de etileno) y su uso. | |
| BR9808011A (pt) | Processo para a purificação de caprolactama | |
| PE20001377A1 (es) | Una composicion de alta pureza de (7alfa,17alfa)-17-hidroxi-7-metil-19-nor-17-pregn-5(10)-en-20-in-3-ona | |
| PT98519A (pt) | Processo para a preparacao de 4-amino-delta 4,6-esteroides com accao inibidora da 5-alfa-redutase | |
| BR0108265A (pt) | Processo para remover resìduo de catalisador de hidrogenação de polìmeros hidrogenados | |
| BRPI0407448A (pt) | Processo quìmico | |
| BR9811437A (pt) | Processo para aumentar a pureza óptica do r-amino álcool | |
| DE69900892D1 (de) | Verfahren zur Herstellung von Racemisch Sertralin | |
| BR0015914A (pt) | Método para emendar conteúdos de banco de dados | |
| ES2122941B1 (es) | Procedimiento para la obtencion de quinapril clorhidrato y solvatos utiles para el aislamiento y purificacion de quinapril clorhidrato. | |
| MX9100983A (es) | Metodo para la purificacion de mezclas que comprenden ibuprofen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/06/2000, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 19.06.2020 |