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BG60752B2 - Метод за повишаване растежа на животни с фенеталови амини - Google Patents

Метод за повишаване растежа на животни с фенеталови амини Download PDF

Info

Publication number
BG60752B2
BG60752B2 BG098574A BG9857494A BG60752B2 BG 60752 B2 BG60752 B2 BG 60752B2 BG 098574 A BG098574 A BG 098574A BG 9857494 A BG9857494 A BG 9857494A BG 60752 B2 BG60752 B2 BG 60752B2
Authority
BG
Bulgaria
Prior art keywords
compound
hydroxyphenyl
animals
methyl
formula
Prior art date
Application number
BG098574A
Other languages
Bulgarian (bg)
English (en)
Inventor
David Anderson
Klaus Schmiegel
Edward Veenhuizen
Ronald Tuttle
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of BG60752B2 publication Critical patent/BG60752B2/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/111—Aromatic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fodder In General (AREA)
BG098574A 1983-01-31 1994-02-25 Метод за повишаване растежа на животни с фенеталови амини BG60752B2 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US46258783A 1983-01-31 1983-01-31

Publications (1)

Publication Number Publication Date
BG60752B2 true BG60752B2 (bg) 1996-02-29

Family

ID=23836986

Family Applications (1)

Application Number Title Priority Date Filing Date
BG098574A BG60752B2 (bg) 1983-01-31 1994-02-25 Метод за повишаване растежа на животни с фенеталови амини

Country Status (25)

Country Link
EP (2) EP0117647B1 (da)
JP (1) JPS59155343A (da)
AU (1) AU577271B2 (da)
BG (1) BG60752B2 (da)
CA (2) CA1247451A (da)
CY (2) CY1433A (da)
DE (2) DE3473439D1 (da)
DK (1) DK171627B1 (da)
FI (1) FI81713C (da)
GB (2) GB2133986B (da)
GR (1) GR79758B (da)
GT (1) GT198400014A (da)
HK (1) HK39090A (da)
HU (1) HU190526B (da)
IE (1) IE56843B1 (da)
IL (1) IL70813A (da)
MX (1) MX9203041A (da)
MY (1) MY100559A (da)
NZ (1) NZ206985A (da)
PH (1) PH20912A (da)
PL (1) PL144053B1 (da)
SG (1) SG4190G (da)
SU (1) SU1523043A3 (da)
UA (1) UA8350A1 (da)
ZA (1) ZA84721B (da)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602044A (en) * 1983-12-19 1986-07-22 Eli Lilly And Company β-phenethanolamine antiobesity agents
NZ212204A (en) * 1984-06-04 1988-07-28 Merck & Co Inc Growth-promoting compositions containing hydroxylic compounds
GB8505284D0 (en) * 1985-03-01 1985-04-03 Beecham Group Plc Growth promoters
PT82120B (en) * 1985-03-01 1988-06-16 Beecham Group Plc Process for preparing veterinary formulations containing ethanolamine derivatives
CA1298785C (en) * 1985-11-27 1992-04-14 David Bennett Anderson Use of phenethanol amines to improve fat content of sow's milk
DE3623940A1 (de) * 1986-07-16 1988-01-21 Bayer Ag Arylethanolhydroxylamine, verfahren zu ihrer herstellung und ihre verwendung zur leistungsfoerderung
DE3631009A1 (de) * 1986-09-12 1988-03-24 Bayer Ag Arylethanolamine, verfahren zu ihrer herstellung und ihre verwendung zur leistungsfoerderung
US5530029A (en) * 1987-09-15 1996-06-25 The Rowett Research Institute Therapeutic applications of clenbuterol
US5552442A (en) * 1987-09-15 1996-09-03 The Rowett Research Institute Therapeutic applications of clenbuterol
ATE149089T1 (de) * 1987-09-15 1997-03-15 Rowett Research Inst Anwendungsgebiete von beta-adrenergenen agonisten
US5108363A (en) * 1988-02-19 1992-04-28 Gensia Pharmaceuticals, Inc. Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist
CN1073983C (zh) * 1994-10-31 2001-10-31 中国科学院成都有机化学研究所 一种β－拟肾上腺素兴奋剂型饲料添加剂的合成方法
CN1082042C (zh) * 1997-06-09 2002-04-03 中国科学院成都有机化学研究所 莱克多巴胺的合成方法
DK1633340T3 (da) * 2003-04-15 2011-02-07 Wellstat Therapeutics Corp Forbindelser til behandling af stofskifteforstyrrelser
WO2005036980A1 (en) * 2003-10-07 2005-04-28 Eli Lilly And Company Liquid formulations of ractopamine
PT2346349E (pt) * 2008-09-18 2015-02-04 Elanco Animal Health Ireland Utilização de azaperona para melhorar o desempenho do crescimento
US9192585B2 (en) 2009-07-31 2015-11-24 Cognition Therapeutics, Inc. Inhibitors of cognitive decline
CN102060716A (zh) * 2009-11-15 2011-05-18 海南中化联合制药工业股份有限公司 一种盐酸利托君的制备方法
RU2014111079A (ru) * 2011-08-25 2015-09-27 Когнишн Терапьютикс, Инк. Композиции и способы для лечения нейродегенеративного заболевания
RU2528962C9 (ru) * 2012-12-07 2015-02-20 Государственное научное учреждение Поволжский научно-исследовательский институт производства и переработки мясомолочной продукции Российской академии сельскохозяйственных наук Способ выращивания молодняка свиней
WO2014108449A1 (en) 2013-01-08 2014-07-17 Atrogi Ab A screening method, a kit, a method of treatment and a compound for use in a method of treatment
ES2915833T3 (es) 2014-01-31 2022-06-27 Cognition Therapeutics Inc Composiciones de isoindolina y métodos para tratar una enfermedad neurodegenerativa y una degeneración macular
CN104387282B (zh) * 2014-11-13 2016-09-14 上海应用技术学院 一种氘代莱克多巴胺的制备方法
CN104370759B (zh) * 2014-11-13 2016-04-27 上海应用技术学院 一种氘代二甲基莱克多巴胺的制备方法
KR102614814B1 (ko) 2017-05-15 2023-12-20 카그니션 테라퓨틱스, 인코퍼레이티드 신경변성 질환 치료용 조성물
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses
WO2024153813A1 (en) 2023-01-20 2024-07-25 Atrogi Ab Beta 2-adrenergic receptor agonists for treatment or prevention of muscle wasting
GB202302225D0 (en) 2023-02-16 2023-04-05 Atrogi Ab New medical uses
GB202303229D0 (en) 2023-03-06 2023-04-19 Atrogi Ab New medical uses

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE894396C (de) * 1944-05-21 1953-10-26 Troponwerke Dinklage & Co Verfahren zur Herstellung von 1-(o-, m- oder p-Oxyphenyl)-1-oxy-2-aralkylamino-aethanen
DE1543918A1 (de) * 1966-01-28 1970-01-08 Troponwerke Dinklage & Co 1-[m-Hydroxyphenyl]-2-[1-methyl-3-phenylpropyl-(1)-amino]-aethanol-(1) und Verfahren zu dessen Herstellung
US3987200A (en) * 1972-04-12 1976-10-19 Eli Lilly And Company Method for increasing cardiac contractility
US4391826A (en) * 1978-07-03 1983-07-05 Eli Lilly And Company Phenethanolamines, compositions containing the same, and method for effecting weight control
IL57671A (en) * 1978-07-03 1982-11-30 Lilly Co Eli Phenethanolamines,process for their preparation and pharmaceutical and animal feed compositions containing the same
CA1126296A (en) * 1978-07-03 1982-06-22 Jack Mills R-n-(2-phenyl-2-hydroxyethyl)-3-phenylpropyl amines, formulations and method of treatment
CA1120058A (en) * 1978-07-03 1982-03-16 Jack Mills Phenethanolamines, formulations and potentiation of oncolytic drugs
DE3104850A1 (de) * 1981-02-11 1982-08-26 Dr. Karl Thomae Gmbh, 7950 Biberach "neuer futterzusatz zur verbesserung des wachstums"
EP0089154A3 (en) * 1982-03-12 1984-08-08 Beecham Group Plc Ethanolamine derivatives, their preparation and use in pharmaceutical compositions

Also Published As

Publication number Publication date
GR79758B (da) 1984-10-31
GB8614772D0 (en) 1986-07-23
DK171627B1 (da) 1997-03-03
IL70813A (en) 1987-10-30
UA8350A1 (uk) 1996-03-29
HU190526B (en) 1986-09-29
CA1247451A (en) 1988-12-28
GB2177600A (en) 1987-01-28
PH20912A (en) 1987-05-28
FI840369L (fi) 1984-08-01
CY1525A (en) 1990-11-16
FI81713C (fi) 1990-12-10
IE56843B1 (en) 1992-01-01
DK41484A (da) 1984-08-01
GB2133986B (en) 1987-08-26
GB2133986A (en) 1984-08-08
DE3481754D1 (de) 1990-05-03
AU2391584A (en) 1984-08-02
PL144053B1 (en) 1988-04-30
MX9203041A (es) 1992-07-01
EP0204948A1 (en) 1986-12-17
CY1433A (en) 1988-09-02
EP0204948B1 (en) 1990-03-28
SU1523043A3 (ru) 1989-11-15
IE840211L (en) 1984-07-31
GB2177600B (en) 1987-09-03
ZA84721B (en) 1984-09-26
EP0117647A1 (en) 1984-09-05
HK39090A (en) 1990-05-25
FI81713B (fi) 1990-08-31
SG4190G (en) 1990-07-06
HUT37012A (en) 1985-11-28
AU577271B2 (en) 1988-09-22
DE3473439D1 (en) 1988-09-22
CA1275934C (en) 1990-11-06
NZ206985A (en) 1986-09-10
PL245969A1 (en) 1985-01-30
GB8402343D0 (en) 1984-02-29
MY100559A (en) 1990-11-15
IL70813A0 (en) 1984-04-30
JPS59155343A (ja) 1984-09-04
EP0117647B1 (en) 1988-08-17
DK41484D0 (da) 1984-01-30
JPH0320225B2 (da) 1991-03-18
GT198400014A (es) 1985-07-23
FI840369A0 (fi) 1984-01-30

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