BG60207B2 - Process for preparing n-substituted 3-acyl-2-oxindole-1-carboxamides - Google Patents
Process for preparing n-substituted 3-acyl-2-oxindole-1-carboxamidesInfo
- Publication number
- BG60207B2 BG60207B2 BG096583A BG9658392A BG60207B2 BG 60207 B2 BG60207 B2 BG 60207B2 BG 096583 A BG096583 A BG 096583A BG 9658392 A BG9658392 A BG 9658392A BG 60207 B2 BG60207 B2 BG 60207B2
- Authority
- BG
- Bulgaria
- Prior art keywords
- oxindole
- carboxamides
- acyl
- substituted
- preparing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- -1 pyridile Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- HRDXJKGNWSUIBT-UHFFFAOYSA-N methoxybenzene Chemical group [CH2]OC1=CC=CC=C1 HRDXJKGNWSUIBT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
- 125000005301 thienylmethyl group Chemical group [H]C1=C([H])C([H])=C(S1)C([H])([H])* 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/60—Naphtho [b] pyrroles; Hydrogenated naphtho [b] pyrroles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60735684A | 1984-05-04 | 1984-05-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG60207B2 true BG60207B2 (en) | 1993-12-30 |
Family
ID=24431933
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG070071A BG60208B2 (en) | 1984-05-04 | 1985-05-03 | Process for preparingn-substituted 3-acyl-2-oxindole-1-carboxamides |
| BG096583A BG60207B2 (en) | 1984-05-04 | 1992-07-08 | Process for preparing n-substituted 3-acyl-2-oxindole-1-carboxamides |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG070071A BG60208B2 (en) | 1984-05-04 | 1985-05-03 | Process for preparingn-substituted 3-acyl-2-oxindole-1-carboxamides |
Country Status (25)
| Country | Link |
|---|---|
| JP (1) | JPS60243068A (xx) |
| KR (1) | KR870000497B1 (xx) |
| AR (1) | AR241159A1 (xx) |
| BG (2) | BG60208B2 (xx) |
| CS (1) | CS252828B2 (xx) |
| DD (1) | DD232916A5 (xx) |
| EG (1) | EG17193A (xx) |
| ES (2) | ES8609248A1 (xx) |
| FI (1) | FI80016C (xx) |
| HU (1) | HU196057B (xx) |
| IE (1) | IE851103L (xx) |
| IN (1) | IN161509B (xx) |
| MA (1) | MA20424A1 (xx) |
| MW (1) | MW1685A1 (xx) |
| MX (1) | MX5839A (xx) |
| NO (1) | NO163132C (xx) |
| OA (1) | OA08098A (xx) |
| PL (2) | PL147508B1 (xx) |
| PT (1) | PT80375B (xx) |
| RO (2) | RO94455B (xx) |
| RU (1) | RU2017729C1 (xx) |
| SU (1) | SU1468413A3 (xx) |
| YU (1) | YU44998B (xx) |
| ZA (1) | ZA853324B (xx) |
| ZW (1) | ZW7885A1 (xx) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5047554A (en) * | 1989-04-18 | 1991-09-10 | Pfizer Inc. | 3-substituted-2-oxindole derivatives |
| IL95880A (en) * | 1989-10-13 | 1995-12-31 | Pfizer | Use of 3-Transformed History of 2-Oxindole for the Preparation of Pharmaceuticals for Inhibition of Interlaukio-1 Biosynthesis |
-
1985
- 1985-04-08 IN IN288/DEL/85A patent/IN161509B/en unknown
- 1985-04-30 PT PT80375A patent/PT80375B/pt unknown
- 1985-04-30 YU YU730/85A patent/YU44998B/xx unknown
- 1985-05-02 JP JP60095275A patent/JPS60243068A/ja active Granted
- 1985-05-02 IE IE851103A patent/IE851103L/xx unknown
- 1985-05-02 AR AR300259A patent/AR241159A1/es active
- 1985-05-02 EG EG275/85A patent/EG17193A/xx active
- 1985-05-02 DD DD85275898A patent/DD232916A5/de not_active IP Right Cessation
- 1985-05-03 NO NO851774A patent/NO163132C/no not_active IP Right Cessation
- 1985-05-03 ZA ZA853324A patent/ZA853324B/xx unknown
- 1985-05-03 OA OA58583A patent/OA08098A/xx unknown
- 1985-05-03 PL PL1985257892A patent/PL147508B1/pl unknown
- 1985-05-03 PL PL1985253203A patent/PL145416B1/pl unknown
- 1985-05-03 RO RO123678A patent/RO94455B/ro unknown
- 1985-05-03 RO RO118604A patent/RO91141B/ro unknown
- 1985-05-03 ES ES542813A patent/ES8609248A1/es not_active Expired
- 1985-05-03 FI FI851756A patent/FI80016C/fi not_active IP Right Cessation
- 1985-05-03 BG BG070071A patent/BG60208B2/xx unknown
- 1985-05-03 MX MX583985A patent/MX5839A/es unknown
- 1985-05-03 MW MW16/85A patent/MW1685A1/xx unknown
- 1985-05-03 KR KR1019850003013A patent/KR870000497B1/ko not_active IP Right Cessation
- 1985-05-03 MA MA20648A patent/MA20424A1/fr unknown
- 1985-05-03 ZW ZW78/85A patent/ZW7885A1/xx unknown
- 1985-05-04 RU SU853891002A patent/RU2017729C1/ru active
- 1985-05-04 CS CS853202A patent/CS252828B2/cs not_active IP Right Cessation
- 1985-05-31 HU HU851693A patent/HU196057B/hu unknown
-
1986
- 1986-01-27 ES ES551275A patent/ES8707182A1/es not_active Expired
- 1986-05-12 SU SU864027453A patent/SU1468413A3/ru active
-
1992
- 1992-07-08 BG BG096583A patent/BG60207B2/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0176927A3 (en) | Diazepine-containing pharmaceutical compositions having a platelet activating factor (paf)-antagonist action | |
| NO179868C (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktive kondenserte heterocykliske forbindelser | |
| KR830007597A (ko) | 3-아릴-5-이소티아졸 유도체의 제조방법 | |
| ES8406419A1 (es) | Un procedimiento para la preparacion de derivados de areno y hetero-arenocarboxamidas | |
| IE41528L (en) | Furfuryl-benzomorphane derivatives. | |
| ES382550A1 (es) | Procedimiento para la preparacion de nuevas 2-aminoalcohi- lamino-tieno (3,2-d) pirimidinas. | |
| ES8609272A1 (es) | Un procedimiento para preparar derivados de hidantoina | |
| ES8609225A1 (es) | Un procedimiento para preparar un derivado de semicarbazida | |
| BG60207B2 (en) | Process for preparing n-substituted 3-acyl-2-oxindole-1-carboxamides | |
| ES8701174A1 (es) | Un metodo de preparacion de un compuesto de tiadiazina | |
| HUT49581A (en) | Process for producing imidazole derivatives and pharmaceutical compositions comprising same | |
| IE810728L (en) | Pyrazole derivatives. | |
| IE39576L (en) | DERIVATIVES OF 3- (p-CHLOROBENZOYL)-2-METHYL- PHENYLACETIC¹ACID | |
| KR840001154A (ko) | 1,2-디티올-3-일리덴 암모늄 유도체의 제조방법 | |
| JPS57183768A (en) | 4-methyl-5-(o-carboxyphenyl)carbamoylthiazole derivative and its preparation | |
| IE802112L (en) | Pyridine derivatives. | |
| IE831075L (en) | Thiophene derivatives | |
| ES465346A1 (es) | Procedimiento para preparar imidazoles 4,5-disustituidos. | |
| ES8308565A1 (es) | Procedimiento para la preparacion de compuestos de 1,4-benzodiazepina. | |
| DK342383A (da) | Fremgangsmaade til fremstilling af 4-amino-5-dialkoxymethylpyrimidinderivater | |
| GB1471851A (en) | Diaminomaleonitrile derivatives and processes for preparing the same | |
| ES8802300A1 (es) | Un metodo para preparar derivados de 3-ariloxiazetidincarboxamida | |
| EP0367671A3 (en) | Novel beta-d-phenylthioxylosides, their method of preparation and their use as pharmaceuticals | |
| KR850007599A (ko) | 3-아지노메틸 리파마이신의 제조방법 | |
| ES8302668A1 (es) | Un metodo de produccion de un compuesto 3,5-dt-t-butil-4-hidroxifenil-heterociclico sustituido. |