[go: up one dir, main page]

BG44029A3 - Method for preparing of n- dimethyl morphinanic derivatives - Google Patents

Method for preparing of n- dimethyl morphinanic derivatives

Info

Publication number
BG44029A3
BG44029A3 BG071084A BG7108485A BG44029A3 BG 44029 A3 BG44029 A3 BG 44029A3 BG 071084 A BG071084 A BG 071084A BG 7108485 A BG7108485 A BG 7108485A BG 44029 A3 BG44029 A3 BG 44029A3
Authority
BG
Bulgaria
Prior art keywords
derivatives
morphinanic
dimethyl
preparing
alkylmorphinan
Prior art date
Application number
BG071084A
Other languages
Bulgarian (bg)
Inventor
Sandor Hosztafi
Tibor Timar
Julianna Nagy
Ilona Fabian
Original Assignee
Alkaloida Vegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkaloida Vegyeszeti Gyar filed Critical Alkaloida Vegyeszeti Gyar
Publication of BG44029A3 publication Critical patent/BG44029A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Finger-Pressure Massage (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Materials For Photolithography (AREA)
  • Cephalosporin Compounds (AREA)
  • Electrophonic Musical Instruments (AREA)
  • Stringed Musical Instruments (AREA)

Abstract

Съединенията се използват като междинни продукти за получаване на други n-алкилморфинанови производни с биологична активност. Те се получават с добър добив и висока чистота. 5 претенцииThe compounds are used as intermediates for the preparation of other n-alkylmorphinan derivatives with biological activity. They are obtained in good yield and high purity. 5 claims

BG071084A 1984-07-17 1985-07-15 Method for preparing of n- dimethyl morphinanic derivatives BG44029A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU842774A HU197750B (en) 1984-07-17 1984-07-17 Process for n-demethylation of morphine alkaloids

Publications (1)

Publication Number Publication Date
BG44029A3 true BG44029A3 (en) 1988-09-15

Family

ID=10961043

Family Applications (1)

Application Number Title Priority Date Filing Date
BG071084A BG44029A3 (en) 1984-07-17 1985-07-15 Method for preparing of n- dimethyl morphinanic derivatives

Country Status (18)

Country Link
EP (1) EP0168686B1 (en)
JP (1) JPS6193184A (en)
AT (1) ATE41933T1 (en)
BG (1) BG44029A3 (en)
CS (1) CS251792B2 (en)
DD (1) DD235639A5 (en)
DE (1) DE3569244D1 (en)
DK (1) DK322385A (en)
ES (1) ES8603716A1 (en)
FI (1) FI81583C (en)
HU (1) HU197750B (en)
IL (2) IL75509A0 (en)
IN (1) IN166255B (en)
NO (1) NO161915C (en)
PL (1) PL254552A1 (en)
RO (1) RO91516B (en)
SU (1) SU1398776A3 (en)
YU (1) YU45264B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101896464B (en) * 2007-12-17 2014-12-10 马林克罗特有限公司 Sinomenine derivatives and processes for their synthesis
EP2222642B1 (en) * 2007-12-17 2014-02-12 Mallinckrodt LLC Process and compounds for the production of (+) opiates
CA2761287A1 (en) * 2009-05-12 2010-11-18 Board Of Regents The University Of Texas System Synthesis of morphine and related derivatives
CA2768199C (en) * 2010-07-16 2018-08-28 Mallinckrodt Llc (+)-morphinans as antagonists of toll-like receptor 9 and therapeutic uses thereof
WO2013036729A1 (en) 2011-09-08 2013-03-14 Mallinckrodt Llc Production of alkaloids without the isolation of intermediates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE719019A (en) * 1967-08-04 1969-02-03
DE2254298A1 (en) * 1972-11-06 1974-05-16 Boehringer Sohn Ingelheim Heteroarylmethyl-normorphines prepn - by alkylation of normorphine etc., antidotes for opiate poisoning
DE2727805A1 (en) * 1977-06-21 1979-01-04 Goedecke Ag METHOD FOR PRODUCING OXYNORMORPHONE

Also Published As

Publication number Publication date
RO91516A (en) 1987-06-30
DD235639A5 (en) 1986-05-14
FI81583C (en) 1990-11-12
HUT38645A (en) 1986-06-30
DE3569244D1 (en) 1989-05-11
FI81583B (en) 1990-07-31
RO91516B (en) 1987-07-01
EP0168686A1 (en) 1986-01-22
PL254552A1 (en) 1986-07-15
ATE41933T1 (en) 1989-04-15
CS528085A2 (en) 1986-12-18
ES544385A0 (en) 1986-01-16
HU197750B (en) 1989-05-29
IL75509A0 (en) 1985-10-31
YU45264B (en) 1992-05-28
SU1398776A3 (en) 1988-06-15
FI852779L (en) 1986-01-18
JPS6193184A (en) 1986-05-12
YU117485A (en) 1988-04-30
IL78503A (en) 1990-01-18
FI852779A0 (en) 1985-07-15
NO161915C (en) 1989-10-11
IN166255B (en) 1990-03-31
ES8603716A1 (en) 1986-01-16
DK322385D0 (en) 1985-07-15
DK322385A (en) 1986-01-18
CS251792B2 (en) 1987-08-13
NO852838L (en) 1986-01-20
NO161915B (en) 1989-07-03
EP0168686B1 (en) 1989-04-05

Similar Documents

Publication Publication Date Title
FI906438A0 (en) Process for the preparation of new therapeutically useful A-nor-steroid-3-carboxylic acid derivatives
PT82127A (en) Process for the preparation of phenyl carbamates
PT87754A (en) PROCESS FOR THE PREPARATION OF NEW AMINO ACID DERIVATIVES
BG35189A3 (en) Method for preparing derivatives of 6- beta- hydroxyalkylpenicillanic acid
FI884806A (en) Process for the preparation of therapeutically useful substituted tetralins, chromanes and closely related compounds, as well as intermediates useful in the process
PT80489B (en) PROCESS FOR THE PREPARATION OF NOVEL HETEROCYCLIC DERIVATIVES USEFULLY AS INNIBITORS OF ALDOSE REDUCTASE
BG42835A3 (en) Method for preparing derivatives of thiazolylacetic acid
IT1156487B (en) PROCEDURE AND MICRO-ORGANISMS FOR THE PRODUCTION OF LYSINE BY FERMENTATION
IT1218065B (en) PROCEDURE FOR PA PREPARATION OF 1,2,5,6,9,10 HEXABROMOCYCLODODECANE
IT8420358A0 (en) PROCEDURE FOR THE PREPARATION OF 1-CARBAMOYLMETHYL DERIVATIVES OF 4-HYDROXY-2-OXO-PYRROLIDINE AS WELL AS INTERMEDIATES TO OBTAIN SUCH COMPOUNDS.
BG37992A3 (en) Method for preparing derivatives of benzamide
BG44029A3 (en) Method for preparing of n- dimethyl morphinanic derivatives
BG32418A3 (en) Method for obtaining of amid derivatives of 1, 2, 3- thiadiazol- 5- carbonic acid
RO89363A (en) PROCESS FOR THE PREPARATION OF CEFALOSPORINE
BG44203A3 (en) Method for preparing of 2- oxyindol- 1- carboxamides
IT1099161B (en) PROCESS FOR THE PREPARATION OF GRANULATES EQUIPPED WITH BIOLOGICAL ACTIVITY
IT8567141A0 (en) PROCEDURE FOR THE CULTURE OF CELLS BY GAS DISPERSION
IT8621094A0 (en) PROCEDURE FOR THE PRODUCTION OF COUPLED ZIPPERS.
AU585279B2 (en) Pesticidal biphenylyloxy and biphenylylalkoxy aryl acyl urea compounds
BG40653A3 (en) Method for preparing amidothiocarbamate derivatives of carbon acid
IT1206247B (en) METHOD AND COMPOSITION TO IMPROVE THE GROWTH SCHEME OF ANIMALS
ES546136A0 (en) PROCESS TO PRODUCE DERIVATIVES OF 1,4-DIHIDRO-PIRIDINA-3,5, DICARBOXILATO.
BG47345A3 (en) Method for preparing of dialkyloxalacetates
MX7343E (en) MICROBIOLOGICAL PROCEDURE FOR THE PRODUCTION OF L-SERINE
PT81139A (en) PROCESS FOR THE PREPARATION OF NOVEL (ALCOXY-2) PHENYLPIPERAZINIC DERIVATIVES