BG31224A3 - Method for obtaining the derivatives of enkefaline - Google Patents

Method for obtaining the derivatives of enkefaline

Info

Publication number: BG31224A3
Authority: BG; Bulgaria
Prior art keywords: obtaining; derivatives; enkefaline; proven; formulated
Prior art date: 1977-10-03

Application number

BG040985A

Other languages

Bulgarian (bg)

English (en)

Inventor

Edward Smithwick

Robert Frederickson

Robert Shuman

Original Assignee

Eli Lilly And Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-10-03

Filing date

1978-10-02

Publication date

1981-11-16

1978-10-02 Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company

1981-11-16 Publication of BG31224A3 publication Critical patent/BG31224A3/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

BG040985A 1977-10-03 1978-10-02 Method for obtaining the derivatives of enkefaline BG31224A3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/838,516 US4264491A (en)	1977-10-03	1977-10-03	Analgesic compounds

Publications (1)

Publication Number	Publication Date
BG31224A3 true BG31224A3 (en)	1981-11-16

Family

ID=25277291

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BG040985A BG31224A3 (en)	1977-10-03	1978-10-02	Method for obtaining the derivatives of enkefaline

Country Status (33)

Country	Link
US (1)	US4264491A (ro)
EP (1)	EP0001684B1 (ro)
JP (1)	JPS5459247A (ro)
AR (1)	AR224238A1 (ro)
AT (1)	AT367028B (ro)
AU (1)	AU520315B2 (ro)
BE (1)	BE870819A (ro)
BG (1)	BG31224A3 (ro)
CA (1)	CA1156219A (ro)
CH (1)	CH635571A5 (ro)
CS (1)	CS235072B2 (ro)
DD (1)	DD139710A5 (ro)
DE (1)	DE2861019D1 (ro)
DK (1)	DK149231C (ro)
EG (1)	EG13636A (ro)
ES (1)	ES473925A1 (ro)
FI (1)	FI66842C (ro)
FR (1)	FR2404629B1 (ro)
GB (1)	GB2005688B (ro)
GR (1)	GR71651B (ro)
HU (1)	HU182866B (ro)
IE (1)	IE47378B1 (ro)
IL (1)	IL55650A (ro)
IT (1)	IT1100839B (ro)
LU (1)	LU80316A1 (ro)
NZ (1)	NZ188521A (ro)
PH (1)	PH14660A (ro)
PL (1)	PL114271B1 (ro)
PT (1)	PT68598A (ro)
RO (1)	RO76176A (ro)
SU (1)	SU908246A3 (ro)
YU (1)	YU231578A (ro)
ZA (1)	ZA785564B (ro)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK28377A (da)	1976-02-02	1977-08-03	Sandoz Ag	Fremgangsmade til fremstilling af polypeptidderivater
US4331593A (en) *	1977-10-03	1982-05-25	Smithwick Jr Edward L	Analgesic compounds
US4333873A (en)	1979-12-17	1982-06-08	Eli Lilly And Company	Pharmacologically active peptides
US4283330A (en) *	1979-12-17	1981-08-11	Eli Lilly And Company	Pharmacologically active peptides
US4265808A (en) *	1979-12-17	1981-05-05	Eli Lilly And Company	Pharmacologically active peptides
JPS5692846A (en) *	1979-12-27	1981-07-27	Takeda Chem Ind Ltd	Tetrapeptide derivative and its preparation
FR2488253A1 (fr) *	1980-08-08	1982-02-12	Roques Bernard	Nouveaux peptides et leur application en therapeutique
JPS5738756A (en) *	1980-08-18	1982-03-03	Earth Chem Corp Ltd	Tripeptide alkylamide derivative
JPS5785349A (en) *	1980-11-14	1982-05-28	Earth Chem Corp Ltd	Tripeptide alkylamide derivative
US4322340A (en) *	1980-10-20	1982-03-30	Eli Lilly And Company	Pharmacologically active peptides
JPS5772950A (en) *	1980-10-24	1982-05-07	Takeda Chem Ind Ltd	Tetrapeptide derivative, its preparation and analgesic agent
DE3267380D1 (en) *	1981-06-22	1985-12-19	Ici Plc	Peptides and pseudopeptides in which the n terminus bears two substituents
US4448717A (en) *	1982-11-12	1984-05-15	Eli Lilly And Company	Pharmacologically active peptides
US4495178A (en) *	1983-10-06	1985-01-22	G. D. Searle & Co.	Enkephalin analogs

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1042487A (en) *	1964-06-25	1966-09-14	Ici Ltd	Polypeptide derivatives
HU184704B (en) *	1976-01-26	1984-10-29	Wellcome Found	Process for preparing biologically active encephaline analogues
GB1532181A (en) *	1976-02-02	1978-11-15	Beckman Instruments Inc	Pentapetides and a method of preparing them
DK28377A (da) *	1976-02-02	1977-08-03	Sandoz Ag	Fremgangsmade til fremstilling af polypeptidderivater
US4028319A (en) *	1976-05-07	1977-06-07	G. D. Searle & Co.	2 and 3-substituted enkephalins
DE2732451A1 (de) *	1976-07-27	1978-02-02	Reckitt & Colmann Prod Ltd	Peptidverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneipraeparate
FR2359817A1 (fr) *	1976-07-27	1978-02-24	Reckitt & Colmann Prod Ltd	Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant
US4259234A (en) *	1976-09-27	1981-03-31	Eli Lilly And Company	Analgesic compounds

1977
- 1977-10-03 US US05/838,516 patent/US4264491A/en not_active Expired - Lifetime
1978
- 1978-09-26 IE IE1926/78A patent/IE47378B1/en unknown
- 1978-09-26 CA CA000312073A patent/CA1156219A/en not_active Expired
- 1978-09-27 EP EP78300420A patent/EP0001684B1/en not_active Expired
- 1978-09-27 PT PT68598A patent/PT68598A/pt unknown
- 1978-09-27 IL IL55650A patent/IL55650A/xx unknown
- 1978-09-27 AU AU40247/78A patent/AU520315B2/en not_active Expired
- 1978-09-27 GB GB7838386A patent/GB2005688B/en not_active Expired
- 1978-09-27 NZ NZ188521A patent/NZ188521A/xx unknown
- 1978-09-27 DE DE7878300420T patent/DE2861019D1/de not_active Expired
- 1978-09-28 BE BE1009078A patent/BE870819A/xx not_active IP Right Cessation
- 1978-09-28 JP JP11984778A patent/JPS5459247A/ja active Pending
- 1978-09-28 CS CS786285A patent/CS235072B2/cs unknown
- 1978-09-29 FR FR7827954A patent/FR2404629B1/fr not_active Expired
- 1978-09-29 HU HU78EI814A patent/HU182866B/hu unknown
- 1978-09-29 PH PH21652A patent/PH14660A/en unknown
- 1978-09-29 FI FI782971A patent/FI66842C/fi not_active IP Right Cessation
- 1978-10-02 SU SU782669396A patent/SU908246A3/ru active
- 1978-10-02 BG BG040985A patent/BG31224A3/xx unknown
- 1978-10-02 RO RO7895316A patent/RO76176A/ro unknown
- 1978-10-02 ZA ZA785564A patent/ZA785564B/xx unknown
- 1978-10-02 IT IT28359/78A patent/IT1100839B/it active
- 1978-10-02 YU YU02315/78A patent/YU231578A/xx unknown
- 1978-10-02 GR GR57355A patent/GR71651B/el unknown
- 1978-10-02 AT AT0708778A patent/AT367028B/de not_active IP Right Cessation
- 1978-10-02 DK DK434778A patent/DK149231C/da not_active IP Right Cessation
- 1978-10-02 CH CH1020578A patent/CH635571A5/fr not_active IP Right Cessation
- 1978-10-03 PL PL1978210045A patent/PL114271B1/pl unknown
- 1978-10-03 DD DD78208248A patent/DD139710A5/de unknown
- 1978-10-03 EG EG585/78A patent/EG13636A/xx active
- 1978-10-03 AR AR273938A patent/AR224238A1/es active
- 1978-10-03 ES ES473925A patent/ES473925A1/es not_active Expired
- 1978-10-03 LU LU80316A patent/LU80316A1/xx unknown

Also Published As

Publication number	Publication date
GR71651B (ro)	1983-06-20
ATA708778A (de)	1981-10-15
CA1156219A (en)	1983-11-01
EP0001684B1 (en)	1981-09-02
FR2404629B1 (fr)	1985-12-27
FI66842C (fi)	1984-12-10
IE781926L (en)	1979-04-03
PH14660A (en)	1981-10-20
AR224238A1 (es)	1981-11-13
AU520315B2 (en)	1982-01-28
LU80316A1 (fr)	1979-03-16
EP0001684A3 (en)	1979-06-27
NZ188521A (en)	1981-07-13
RO76176A (ro)	1981-11-04
FI66842B (fi)	1984-08-31
DK434778A (da)	1979-04-04
IT7828359A0 (it)	1978-10-02
IL55650A (en)	1982-02-28
ES473925A1 (es)	1980-01-16
SU908246A3 (ru)	1982-02-23
FR2404629A1 (fr)	1979-04-27
PL114271B1 (en)	1981-01-31
CH635571A5 (fr)	1983-04-15
ZA785564B (en)	1980-05-28
DE2861019D1 (en)	1981-11-26
GB2005688B (en)	1982-02-24
PL210045A1 (pl)	1979-06-18
US4264491A (en)	1981-04-28
FI782971A (fi)	1979-04-04
DK149231B (da)	1986-03-24
EP0001684A2 (en)	1979-05-02
CS235072B2 (en)	1985-04-16
GB2005688A (en)	1979-04-25
YU231578A (en)	1982-10-31
DK149231C (da)	1986-08-18
IT1100839B (it)	1985-09-28
AU4024778A (en)	1980-04-03
BE870819A (fr)	1979-03-28
EG13636A (en)	1982-03-31
PT68598A (en)	1978-10-01
IE47378B1 (en)	1984-03-07
HU182866B (en)	1984-03-28
AT367028B (de)	1982-05-25
JPS5459247A (en)	1979-05-12
DD139710A5 (de)	1980-01-16

Publication	Publication Date	Title
BG31225A3 (en)	1981-11-16	Method for obtaining of acilanilid derivatives
BG33286A3 (en)	1983-01-14	Method for obtaining of 4- hydroxy- 2h- 1, 2- benzothiazin- 3- carboxamid- 1, 1- dioxides
BG28708A3 (en)	1980-06-16	Method of obtaining of imidazole derivatives
BG28065A4 (en)	1980-02-25	Method of obtaining of 2-phenyl-3-aroylbenzothiophenes
BG34338A3 (en)	1983-08-15	Method for obtaining thiadiazolylcephalosporines
BG33294A3 (en)	1983-01-14	Method for obtaining the derivatives of 4- dezacetyl- vincaledcoblactine c- 3- carboxyhydrazid
BG31224A3 (en)	1981-11-16	Method for obtaining the derivatives of enkefaline
BG28700A3 (en)	1980-06-16	Method of obtaining of alkylendiamine derivatives
BG28573A3 (bg)	1980-05-15	Метод за получаване на аминоалкоксифенилови производни
BG31498A3 (en)	1982-01-15	Method for obtaining of pyridiliminomethyl benzene derivatives
BG31073A3 (en)	1981-10-15	Method for obtaining of 1, 5- substituated- 2- pyrolidine
BG29870A3 (en)	1981-02-16	Method for obtaining of pyridon compounds
BG28565A3 (bg)	1980-05-15	Метод за получаване на пиролхиноксалинони и пиролбензодиазепинони
BG30021A3 (en)	1981-03-16	Method for obtaining of imidazoisohinolin- dion
BG28574A3 (en)	1980-05-15	Method of obtaining of 4- diphenylmethylene- 1- hydroxybensylpiperidin
BG32117A4 (en)	1982-05-14	Method for obtaining of oleandomicine
BG28845A3 (en)	1980-07-15	Method of obtaining of n- alkyldiphenylamines
BG27897A3 (en)	1980-01-15	Method of obtaining of benzo (c) hinolines
BG30016A3 (en)	1981-03-16	Method for obtaining of bis / nitro zoureid /- polyol derivatives
BG31947A3 (en)	1982-04-15	Method for obtaining of acetidine derivatives
BG33284A3 (en)	1983-01-14	Method for obtaining of pyridazinylhydrazon
BG32718A3 (en)	1982-09-15	Method for obtaininh of derivatives of 4"- deoxy- 4"- aminoeritromizine- a
BG28066A3 (en)	1980-02-25	Method of obtaining of pyridobenzodiazepinones
BG29285A3 (en)	1980-10-15	Method of obtaining of 3- di- n- propyl- acetoxy- benzodiazepin- 2- on
BG33157A3 (en)	1982-12-15	Method for obtaining of triazon derivatives