BG29287A3 - Method of obtaining of substituated 6- phenyl- 1, 2, 4- triazol (4, 3- b)- pyridazin - Google Patents
Method of obtaining of substituated 6- phenyl- 1, 2, 4- triazol (4, 3- b)- pyridazinInfo
- Publication number
- BG29287A3 BG29287A3 BG037371A BG3737177A BG29287A3 BG 29287 A3 BG29287 A3 BG 29287A3 BG 037371 A BG037371 A BG 037371A BG 3737177 A BG3737177 A BG 3737177A BG 29287 A3 BG29287 A3 BG 29287A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- phenyl
- substituated
- pyridazin
- triazol
- obtaining
- Prior art date
Links
- -1 substituted Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/08—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/12—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/20—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/725,597 US4230705A (en) | 1976-09-22 | 1976-09-22 | 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazines and their uses in treating anxiety |
| US73039576A | 1976-10-07 | 1976-10-07 | |
| US73547576A | 1976-10-26 | 1976-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG29287A3 true BG29287A3 (en) | 1980-10-15 |
Family
ID=27419081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG037371A BG29287A3 (en) | 1976-09-22 | 1977-09-20 | Method of obtaining of substituated 6- phenyl- 1, 2, 4- triazol (4, 3- b)- pyridazin |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS5340798A (xx) |
| AR (2) | AR218036A1 (xx) |
| AT (1) | AT360034B (xx) |
| AU (1) | AU513760B2 (xx) |
| BG (1) | BG29287A3 (xx) |
| CA (1) | CA1080712A (xx) |
| DD (1) | DD132586A5 (xx) |
| DE (1) | DE2741763A1 (xx) |
| DK (1) | DK417377A (xx) |
| ES (3) | ES462543A1 (xx) |
| FI (1) | FI772802A (xx) |
| FR (1) | FR2442848A1 (xx) |
| GB (1) | GB1589237A (xx) |
| GR (1) | GR71699B (xx) |
| LU (1) | LU78150A1 (xx) |
| NL (1) | NL7710389A (xx) |
| NO (1) | NO773245L (xx) |
| PT (1) | PT67067B (xx) |
| RO (1) | RO72226A (xx) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR70309B (xx) * | 1979-10-29 | 1982-09-08 | Dow Chemical Co | |
| FR2473522A1 (fr) * | 1980-01-16 | 1981-07-17 | Synthelabo | Nouveaux derives substitues de dihydro-2,3 imidazo(1,2-b)pyridazines et les medicaments, utiles notamment comme antidepresseurs, qui en contiennent |
| EP0036711B1 (en) * | 1980-03-22 | 1985-12-04 | Fbc Limited | Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use |
| DE3217325A1 (de) * | 1982-05-08 | 1983-11-10 | Hoechst Ag, 6230 Frankfurt | 3-amino-6-aryl-1,2,4-triazolo(4,3-b)-pyridazine, ihre herstellung und ihre verwendung |
| US4487930A (en) * | 1982-09-07 | 1984-12-11 | The Dow Chemical Company | 6-[(Cyclic amino)alkylamino]-tetrahydrotriazolo[3,4-a]phthalazines |
| FR2562071B1 (fr) * | 1984-03-30 | 1986-12-19 | Sanofi Sa | Triazolo(4,3-b)pyridazines, procede pour leur preparation et compositions pharmaceutiques les contenant |
| US4654343A (en) * | 1985-10-31 | 1987-03-31 | American Cyanamid Company | N-substituted-N[3-(1,2,4-triazolo[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas |
| US4767765A (en) * | 1985-10-31 | 1988-08-30 | American Cyanamid Company | N-substituted-N-[3-(1,2,4-triazolo-[4,3-b]pyridazin-6-yl)phenyl]alkanamides, carbamates and ureas |
| TR199900047T2 (xx) * | 1996-07-25 | 1999-03-22 | Merck Sharp & Dohme Limited | Gaba resept�rleri ligandlar� olarak ikame triazolo-piridazin t�revleri |
| AU746866B2 (en) | 1998-01-14 | 2002-05-02 | Merck Sharp & Dohme Limited | Triazolo-pyridazine derivatives as ligands for GABA receptors |
| GB9801234D0 (en) * | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801208D0 (en) * | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801202D0 (en) | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801210D0 (en) | 1998-01-21 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| CZ290883B6 (cs) | 1998-01-21 | 2002-11-13 | Merck Sharp And Dohme Limited | Triazolopyridazinové deriváty, způsob jejich výroby a farmaceutický prostředek je obsahující |
| GB9801397D0 (en) | 1998-01-22 | 1998-03-18 | Merck Sharp & Dohme | Therapeutic agents |
| GB9801538D0 (en) | 1998-01-23 | 1998-03-25 | Merck Sharp & Dohme | Pharmaceutical product |
| CN1922183B (zh) * | 2004-02-18 | 2010-05-26 | 万有制药株式会社 | 含氮的稠合杂芳环衍生物 |
| BR112019010880A2 (pt) | 2016-11-28 | 2019-10-01 | Praxis Prec Medicines Inc | compostos e seus métodos de uso |
| US11866439B2 (en) | 2018-05-30 | 2024-01-09 | Praxis Precision Medicines, Inc. | Ion channel modulators |
| US11773099B2 (en) | 2019-05-28 | 2023-10-03 | Praxis Precision Medicines, Inc. | Compounds and their methods of use |
| US11505554B2 (en) | 2019-05-31 | 2022-11-22 | Praxis Precision Medicines, Inc. | Substituted pyridines as ion channel modulators |
-
1977
- 1977-08-16 CA CA284,806A patent/CA1080712A/en not_active Expired
- 1977-08-19 GR GR54197A patent/GR71699B/el unknown
- 1977-09-07 AR AR269126A patent/AR218036A1/es active
- 1977-09-16 DE DE19772741763 patent/DE2741763A1/de not_active Withdrawn
- 1977-09-20 RO RO7791618A patent/RO72226A/ro unknown
- 1977-09-20 LU LU78150A patent/LU78150A1/xx unknown
- 1977-09-20 BG BG037371A patent/BG29287A3/xx unknown
- 1977-09-21 DK DK417377A patent/DK417377A/da unknown
- 1977-09-21 AT AT677577A patent/AT360034B/de not_active IP Right Cessation
- 1977-09-21 AU AU28995/77A patent/AU513760B2/en not_active Expired
- 1977-09-21 NO NO773245A patent/NO773245L/no unknown
- 1977-09-22 JP JP11344877A patent/JPS5340798A/ja active Pending
- 1977-09-22 FR FR7728639A patent/FR2442848A1/fr active Pending
- 1977-09-22 FI FI772802A patent/FI772802A/fi not_active Application Discontinuation
- 1977-09-22 NL NL7710389A patent/NL7710389A/xx not_active Application Discontinuation
- 1977-09-22 ES ES462543A patent/ES462543A1/es not_active Expired
- 1977-09-22 PT PT67067A patent/PT67067B/pt unknown
- 1977-09-22 GB GB39619/77A patent/GB1589237A/en not_active Expired
- 1977-09-22 DD DD7700201157A patent/DD132586A5/xx unknown
-
1978
- 1978-12-18 AR AR274489A patent/AR217886A1/es active
-
1979
- 1979-02-16 ES ES477799A patent/ES477799A1/es not_active Expired
- 1979-02-16 ES ES477800A patent/ES477800A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES462543A1 (es) | 1979-06-16 |
| ES477799A1 (es) | 1980-04-01 |
| FR2442848A1 (fr) | 1980-06-27 |
| AU2899577A (en) | 1979-03-29 |
| DD132586A5 (de) | 1978-10-11 |
| AR217886A1 (es) | 1980-04-30 |
| NL7710389A (nl) | 1978-03-28 |
| RO72226A (ro) | 1982-09-09 |
| LU78150A1 (xx) | 1978-01-23 |
| ES477800A1 (es) | 1979-10-16 |
| PT67067A (en) | 1977-10-01 |
| AT360034B (de) | 1980-12-10 |
| PT67067B (en) | 1979-02-19 |
| DE2741763A1 (de) | 1978-03-23 |
| AU513760B2 (en) | 1980-12-18 |
| FI772802A (fi) | 1978-03-23 |
| AR218036A1 (es) | 1980-05-15 |
| ATA677577A (de) | 1980-05-15 |
| JPS5340798A (en) | 1978-04-13 |
| GR71699B (xx) | 1983-06-21 |
| NO773245L (no) | 1978-03-28 |
| DK417377A (da) | 1978-03-23 |
| CA1080712A (en) | 1980-07-01 |
| GB1589237A (en) | 1981-05-07 |
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