BG106958A - Method for the preparation of citalopram - Google Patents
Method for the preparation of citalopramInfo
- Publication number
- BG106958A BG106958A BG106958A BG10695802A BG106958A BG 106958 A BG106958 A BG 106958A BG 106958 A BG106958 A BG 106958A BG 10695802 A BG10695802 A BG 10695802A BG 106958 A BG106958 A BG 106958A
- Authority
- BG
- Bulgaria
- Prior art keywords
- preparation
- citalopram
- phthalid
- cyano
- new
- Prior art date
Links
- WSEQXVZVJXJVFP-HXUWFJFHSA-N (R)-citalopram Chemical compound C1([C@@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-HXUWFJFHSA-N 0.000 title abstract 2
- 229960001653 citalopram Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- XEEGWTLAFIZLSF-UHFFFAOYSA-N 1-oxo-3h-2-benzofuran-5-carbonitrile Chemical compound N#CC1=CC=C2C(=O)OCC2=C1 XEEGWTLAFIZLSF-UHFFFAOYSA-N 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention provides a new and improved method for the preparation of 5-cyano-phthalid, which is a key intermediate in the preparation of antidepressant compound citalopram. 13 claims
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BG106958A BG65515B1 (en) | 2002-07-26 | 2002-07-26 | Method for the preparation of 5-cyanophthalide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BG106958A BG65515B1 (en) | 2002-07-26 | 2002-07-26 | Method for the preparation of 5-cyanophthalide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BG106958A true BG106958A (en) | 2003-03-31 |
| BG65515B1 BG65515B1 (en) | 2008-10-31 |
Family
ID=40328095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG106958A BG65515B1 (en) | 2002-07-26 | 2002-07-26 | Method for the preparation of 5-cyanophthalide |
Country Status (1)
| Country | Link |
|---|---|
| BG (1) | BG65515B1 (en) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8419963D0 (en) * | 1984-08-06 | 1984-09-12 | Lundbeck & Co As H | Intermediate compound and method |
| DK213290D0 (en) * | 1990-09-06 | 1990-09-06 | Lundbeck & Co As H | TREATMENT OF CEREBROVASCULAR DISORDERS |
| DK1015416T3 (en) * | 1997-07-08 | 2001-11-05 | Lundbeck & Co As H | Process for the preparation of citalopram |
| UA62985C2 (en) * | 1997-11-10 | 2004-01-15 | Lunnbeck As H | A method for the preparation of citalopram |
| SK283907B6 (en) * | 1997-11-11 | 2004-04-06 | H. Lundbeck A/S | A method for the preparation of citalopram |
-
2002
- 2002-07-26 BG BG106958A patent/BG65515B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BG65515B1 (en) | 2008-10-31 |
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