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BG105725A - Химеричен ген кодиращ антигенни детерминанти на четири протеина на l. infantum - Google Patents

Химеричен ген кодиращ антигенни детерминанти на четири протеина на l. infantum

Info

Publication number
BG105725A
BG105725A BG105725A BG10572501A BG105725A BG 105725 A BG105725 A BG 105725A BG 105725 A BG105725 A BG 105725A BG 10572501 A BG10572501 A BG 10572501A BG 105725 A BG105725 A BG 105725A
Authority
BG
Bulgaria
Prior art keywords
proteins
gene encoding
chimeric gene
infantum
determinants
Prior art date
Application number
BG105725A
Other languages
English (en)
Other versions
BG65569B1 (bg
Inventor
Alonso Carlos Bedate
Original Assignee
C.B.F. Leti S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA2256124A external-priority patent/CA2256124C/en
Application filed by C.B.F. Leti S.A. filed Critical C.B.F. Leti S.A.
Publication of BG105725A publication Critical patent/BG105725A/bg
Publication of BG65569B1 publication Critical patent/BG65569B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Изобретението се отнася до фармацевтичен състав за профилактика и лечение на лейшманиаза при хора или животни. Съставът съдържа химеричния протеин Q,който е продукт на химеричния ген, кодиращ антигенни детерминанти на четири протеина на Leishmania infantum.
BG105725A 1998-12-23 2001-07-23 Химерен ген кодиращ антигенни детерминанти на четири протеина на l. infantum BG65569B1 (bg)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11382598P 1998-12-23 1998-12-23
CA2256124A CA2256124C (en) 1998-12-23 1998-12-23 Chimeric gene formed of the dna sequences that encode the antigenic determinants of four proteins of l. infantum, and protein encoded by said gene, and pharmaceutical composition useful for preventing and/or treating leishmaniosis in animals or humans
PCT/EP1999/010441 WO2000039298A1 (en) 1998-12-23 1999-12-23 Chimeric gene encoding the antigenic determinants of four proteins of l. infantum

Publications (2)

Publication Number Publication Date
BG105725A true BG105725A (bg) 2002-06-28
BG65569B1 BG65569B1 (bg) 2008-12-30

Family

ID=25680668

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105725A BG65569B1 (bg) 1998-12-23 2001-07-23 Химерен ген кодиращ антигенни детерминанти на четири протеина на l. infantum

Country Status (22)

Country Link
EP (1) EP1141305B1 (bg)
CN (1) CN1158387C (bg)
AT (2) ATE429498T1 (bg)
AU (1) AU759316B2 (bg)
BE (1) BE2016C049I2 (bg)
BG (1) BG65569B1 (bg)
BR (1) BRPI9916549B8 (bg)
CY (3) CY1105331T1 (bg)
CZ (1) CZ20012360A3 (bg)
DE (2) DE69931518T2 (bg)
DK (1) DK1141305T3 (bg)
ES (2) ES2273519T3 (bg)
HR (1) HRP20010554A2 (bg)
HU (1) HUP0104743A3 (bg)
IL (2) IL143956A0 (bg)
LU (1) LU93259I2 (bg)
MX (1) MXPA01006548A (bg)
NL (1) NL300830I2 (bg)
PT (2) PT1624063E (bg)
SI (1) SI1624063T1 (bg)
TR (1) TR200102655T2 (bg)
WO (1) WO2000039298A1 (bg)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6613337B1 (en) * 1997-02-12 2003-09-02 Corixa Corporation Leishmania antigens for use in the therapy and diagnosis of leishmaniasis
ES2169995B1 (es) * 2000-04-17 2003-12-01 Leti Lab Composicion a base de la proteina lip2a y su uso en la preparacion de un medicamento para suscitar una respuesta inmune contra un antigeno.
US6673351B1 (en) 2001-03-16 2004-01-06 Astralis, Llc Compositions and methods for the treatment and clinical remission of psoriasis
WO2006058243A2 (en) * 2004-11-24 2006-06-01 Yale University Leishmania antigens and related compositions and uses
MX2010007831A (es) * 2008-01-18 2011-06-20 Leti S L Unipersonal Lab Vacuna que comprende un extracto de proteina ribosomal (rpe) y opcionalmente un adyuvante promotor de th-1.
BR112012000679A2 (pt) * 2009-07-13 2016-11-01 Leti Sl Lab diagnóstico de uma doença parasitária como a leishmaniose utilizando um extrato de proteína ribossômica (epr)
SA110310855B1 (ar) 2009-11-13 2014-09-16 Laboratories Leti S L Unipersonal استخدام مصدر l3 و/ أو l5 كلقاح أو كوسيلة تشخيصية لمرض طفيلي
BR102019003639A2 (pt) * 2019-02-22 2021-11-16 Fundação Oswaldo Cruz Proteína quimérica, seu método para produção e uso, bem como molécula de ácido nucleico, cassete de expressão, vetor de expressão, célula hospedeira, composição para diagnóstico de leishmaniose, kit de diagnóstico de leishmaniose e método de diagnóstico de leishmaniose in vitro
ES2795149B2 (es) 2020-06-08 2022-07-04 Univ Madrid Complutense Quimera sintetica multiepitopica como vacuna y tratamiento frente a leishmaniosis en mamiferos
CN112662694A (zh) * 2020-12-25 2021-04-16 康九生物科技(长春)有限公司 一种麦芽糖结合蛋白、麦芽糖结合蛋白表达载体、重组工程菌及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0703295A1 (en) * 1994-09-26 1996-03-27 Institut Pasteur Vaccine composition comprising recombinant BCG expressing gp 63 fusion protein
US5912166A (en) * 1995-04-21 1999-06-15 Corixa Corporation Compounds and methods for diagnosis of leishmaniasis
ES2133236B1 (es) * 1997-06-27 2000-04-16 Leti Lab Gen quimerico formado por las secuencias de dna que codifican los determinantes antigenicos de cuatro proteinas de l. infantum, aplicable para el diagnostico serologico de leishmaniosis canina y proteina obtenida.

Also Published As

Publication number Publication date
DE69931518D1 (de) 2006-06-29
ES2326174T3 (es) 2009-10-02
DK1141305T3 (da) 2006-09-25
ES2273519T3 (es) 2007-05-01
LU93259I2 (fr) 2016-12-06
TR200102655T2 (tr) 2002-04-22
CZ20012360A3 (cs) 2001-10-17
IL143956A0 (en) 2002-04-21
AU2434200A (en) 2000-07-31
WO2000039298A1 (en) 2000-07-06
PT1624063E (pt) 2009-06-19
HUP0104743A2 (hu) 2002-03-28
CY1105331T1 (el) 2010-03-03
EP1141305B1 (en) 2006-05-24
ATE429498T1 (de) 2009-05-15
DE69940793D1 (de) 2009-06-04
CY2016033I1 (el) 2017-03-15
CN1158387C (zh) 2004-07-21
BRPI9916549B1 (pt) 2018-10-02
MXPA01006548A (es) 2003-03-27
ATE327332T1 (de) 2006-06-15
EP1141305A1 (en) 2001-10-10
CY1109221T1 (el) 2014-07-02
BG65569B1 (bg) 2008-12-30
BRPI9916549B8 (pt) 2022-08-30
BE2016C049I2 (bg) 2019-03-05
DE69931518T2 (de) 2006-12-21
BR9916549A (pt) 2005-01-04
PT1141305E (pt) 2006-10-31
HUP0104743A3 (en) 2004-10-28
SI1624063T1 (sl) 2009-08-31
CY2016033I2 (el) 2017-03-15
HRP20010554A2 (en) 2002-08-31
CN1335889A (zh) 2002-02-13
NL300830I1 (nl) 2016-09-28
AU759316B2 (en) 2003-04-10
IL143956A (en) 2010-11-30
NL300830I2 (nl) 2020-08-31

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