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BG104757A - Pellets having a core coated with a lipid lowering agent and a polymer - Google Patents

Pellets having a core coated with a lipid lowering agent and a polymer

Info

Publication number
BG104757A
BG104757A BG104757A BG10475700A BG104757A BG 104757 A BG104757 A BG 104757A BG 104757 A BG104757 A BG 104757A BG 10475700 A BG10475700 A BG 10475700A BG 104757 A BG104757 A BG 104757A
Authority
BG
Bulgaria
Prior art keywords
pellets
lowering agent
lipid lowering
polymer
core coated
Prior art date
Application number
BG104757A
Other languages
Bulgarian (bg)
Inventor
Conde Valentin De
Paul Gilis
Peter Putteman
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of BG104757A publication Critical patent/BG104757A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The present invention is concerned with pellets comprising a 250-1180 micrometer (16-60 mesh) sugar sphere, a coating film of a water-soluble polymer and a sparingly soluble lipid lowering agent, and a seal coating layer; pharmaceutical dosage forms comprising said pellets and a method of preparing said pellets. 20 claims
BG104757A 1998-04-27 2000-09-12 Pellets having a core coated with a lipid lowering agent and a polymer BG104757A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98201331 1998-04-27
PCT/EP1999/002768 WO1999055313A1 (en) 1998-04-27 1999-04-20 Pellets having a core coated with a lipid lowering agent and a polymer

Publications (1)

Publication Number Publication Date
BG104757A true BG104757A (en) 2001-05-31

Family

ID=8233644

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104757A BG104757A (en) 1998-04-27 2000-09-12 Pellets having a core coated with a lipid lowering agent and a polymer

Country Status (14)

Country Link
EP (1) EP1073424A1 (en)
JP (1) JP2002544118A (en)
KR (1) KR20010041460A (en)
CN (1) CN1308523A (en)
AU (1) AU3710099A (en)
BG (1) BG104757A (en)
BR (1) BR9909963A (en)
CA (1) CA2328970A1 (en)
EE (1) EE200000796A (en)
HU (1) HUP0102052A3 (en)
NO (1) NO20005426D0 (en)
PL (1) PL358909A1 (en)
SK (1) SK15252000A3 (en)
WO (1) WO1999055313A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60209673T2 (en) * 2002-10-22 2006-09-21 Rohm And Haas Co. tablet coating
US8246986B2 (en) 2003-09-26 2012-08-21 Alza Corporation Drug coating providing high drug loading
AU2005205933B2 (en) * 2004-01-21 2010-02-18 Elanco Animal Health Ireland Limited Mitratapide oral solution
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
FR2897267A1 (en) * 2006-02-16 2007-08-17 Flamel Technologies Sa MULTIMICROPARTICULAR PHARMACEUTICAL FORMS FOR PER OS ADMINISTRATION
CN112074505B (en) 2018-03-08 2024-04-05 因赛特公司 Aminopyrazine diol compounds as PI 3K-gamma inhibitors
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RO118715B1 (en) * 1994-10-27 2003-09-30 Janssen Pharmaceutica Nv Apolipoprotein-b synthesis inhibitors

Also Published As

Publication number Publication date
CA2328970A1 (en) 1999-11-04
EE200000796A (en) 2002-06-17
HUP0102052A3 (en) 2002-10-28
NO20005426L (en) 2000-10-27
HUP0102052A2 (en) 2002-05-29
PL358909A1 (en) 2004-08-23
WO1999055313A1 (en) 1999-11-04
SK15252000A3 (en) 2001-10-08
AU3710099A (en) 1999-11-16
JP2002544118A (en) 2002-12-24
EP1073424A1 (en) 2001-02-07
NO20005426D0 (en) 2000-10-27
KR20010041460A (en) 2001-05-25
CN1308523A (en) 2001-08-15
BR9909963A (en) 2000-12-26

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