[go: up one dir, main page]

BG104291A - 3-заместени тетрахидропиридопиримидинонови производни, тяхното получаване и използване - Google Patents

3-заместени тетрахидропиридопиримидинонови производни, тяхното получаване и използване

Info

Publication number
BG104291A
BG104291A BG104291A BG10429100A BG104291A BG 104291 A BG104291 A BG 104291A BG 104291 A BG104291 A BG 104291A BG 10429100 A BG10429100 A BG 10429100A BG 104291 A BG104291 A BG 104291A
Authority
BG
Bulgaria
Prior art keywords
producing
same
derivatives
substituted
substituted tetrahydropyridopyrimidinone
Prior art date
Application number
BG104291A
Other languages
English (en)
Inventor
Wilfried Lubisch
Uta Dullweber
Dorothea Starck
Gerd Steiner
Alfred Bach
Franz Emling
Xavier Garcia-Ladona
Hans-Juergen Teschendorf
Karsten Wicke
Original Assignee
Basf Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Aktiengesellschaft filed Critical Basf Aktiengesellschaft
Publication of BG104291A publication Critical patent/BG104291A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Structure And Mechanism Of Cameras (AREA)

Abstract

Изобретението се отнася до нови 3-заместени тетрахидропиридопиримидинонови производни с формула@@в която заместителите имат значенията, посочени в описанието, до методи за получаване и до използването им като лекарствени средства.
BG104291A 1997-10-24 2000-04-03 3-заместени тетрахидропиридопиримидинонови производни, тяхното получаване и използване BG104291A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19747063A DE19747063A1 (de) 1997-10-24 1997-10-24 3-substituierte Tetrahydropyridopyrimidinon-Derivate, ihre Herstellung und Verwendung
PCT/EP1998/006305 WO1999021857A1 (de) 1997-10-24 1998-10-05 3-substituierte tetrahydropyridopyrimidinon-derivate, ihre herstellung und verwendung

Publications (1)

Publication Number Publication Date
BG104291A true BG104291A (bg) 2001-05-31

Family

ID=7846539

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104291A BG104291A (bg) 1997-10-24 2000-04-03 3-заместени тетрахидропиридопиримидинонови производни, тяхното получаване и използване

Country Status (27)

Country Link
US (1) US6414157B1 (bg)
EP (1) EP1025100B1 (bg)
JP (1) JP2001521035A (bg)
KR (1) KR20010015787A (bg)
CN (1) CN1277611A (bg)
AR (1) AR015466A1 (bg)
AT (1) ATE212346T1 (bg)
AU (1) AU748666B2 (bg)
BG (1) BG104291A (bg)
BR (1) BR9812970A (bg)
CA (1) CA2305258A1 (bg)
CO (1) CO4980862A1 (bg)
DE (2) DE19747063A1 (bg)
DK (1) DK1025100T3 (bg)
ES (1) ES2172222T3 (bg)
HR (1) HRP980554A2 (bg)
HU (1) HUP0004648A3 (bg)
ID (1) ID24633A (bg)
NO (1) NO20001934D0 (bg)
NZ (1) NZ503486A (bg)
PL (1) PL340034A1 (bg)
PT (1) PT1025100E (bg)
SK (1) SK3872000A3 (bg)
TR (1) TR200001102T2 (bg)
TW (1) TW432063B (bg)
WO (1) WO1999021857A1 (bg)
ZA (1) ZA989664B (bg)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19900544A1 (de) * 1999-01-11 2000-07-13 Basf Ag Verwendung von Verbindungen der Formel I zur Prophylaxe und Therapie der zerebralen Ischämie
WO2004014909A1 (en) * 2002-08-13 2004-02-19 Warner-Lambert Company Llc Fused tetrahydropyridine derivatives as matrix metalloproteinase inhibitors
US20040127501A1 (en) * 2002-09-24 2004-07-01 Zhengming Chen Therapeutic agents useful for treating pain
ES2350977T3 (es) 2002-11-05 2011-01-28 Glaxo Group Limited Agentes antibacterianos.
CL2004000409A1 (es) * 2003-03-03 2005-01-07 Vertex Pharma Compuestos derivados de 2-(cilo sustituido)-1-(amino u oxi sustituido)-quinazolina, inhibidores de canales ionicos de sodio y calcio dependientes de voltaje; composicion farmaceutica; y uso del compuesto en el tratamiento de dolor agudo, cronico, neu
US7160888B2 (en) * 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
US20050165025A1 (en) * 2004-01-22 2005-07-28 Recordati Ireland Ltd. Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
DE102004020908A1 (de) 2004-04-28 2005-11-17 Grünenthal GmbH Substituierte 5,6,7,8,-Tetrahydro-pyrido[4,3-d]pyrimidin-2-yl- und 5,6,7,8,-Tetrahydro-chinazolin-2-yl-Verbindungen
CN101189237A (zh) * 2005-04-01 2008-05-28 沃尼尔·朗伯有限责任公司 用于治疗精神分裂症的四氢－吡啶并氮杂䓬－8－酮和相关化合物
US8097610B2 (en) * 2005-08-26 2012-01-17 Shionogi & Co., Ltd. Derivative having PPAR agonistic activity
CN102952129B (zh) * 2011-08-16 2015-09-23 上海师范大学 四氢吡啶并二氢嘧啶酮衍生物及其制备方法和应用
CN116724038A (zh) 2020-10-21 2023-09-08 安力高医药股份有限公司 双环化合物
US11957683B2 (en) 2021-06-18 2024-04-16 Aligos Therapeutics, Inc. Bicyclic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0827149A (ja) * 1994-07-08 1996-01-30 Meiji Seika Kaisha Ltd ピリミジノン誘導体およびその塩

Also Published As

Publication number Publication date
CN1277611A (zh) 2000-12-20
ZA989664B (en) 2000-04-25
NZ503486A (en) 2001-04-27
EP1025100B1 (de) 2002-01-23
NO20001934L (no) 2000-04-13
BR9812970A (pt) 2000-08-08
ES2172222T3 (es) 2002-09-16
US6414157B1 (en) 2002-07-02
TR200001102T2 (tr) 2000-08-21
TW432063B (en) 2001-05-01
ATE212346T1 (de) 2002-02-15
WO1999021857A1 (de) 1999-05-06
HUP0004648A2 (hu) 2001-05-28
DE59802922D1 (de) 2002-03-14
AU9748498A (en) 1999-05-17
HUP0004648A3 (en) 2001-11-28
NO20001934D0 (no) 2000-04-13
CA2305258A1 (en) 1999-05-06
DE19747063A1 (de) 1999-04-29
JP2001521035A (ja) 2001-11-06
SK3872000A3 (en) 2000-09-12
KR20010015787A (ko) 2001-02-26
EP1025100A1 (de) 2000-08-09
DK1025100T3 (da) 2002-05-06
AR015466A1 (es) 2001-05-02
CO4980862A1 (es) 2000-11-27
ID24633A (id) 2000-07-27
PL340034A1 (en) 2001-01-15
PT1025100E (pt) 2002-07-31
AU748666B2 (en) 2002-06-06
HRP980554A2 (en) 1999-08-31

Similar Documents

Publication Publication Date Title
BG103251A (bg) Оксадиазоли, методи за получаването им и приложението им като лекарствени средства
BG101194A (bg) Нови хетероарилови оксазолидинони
BG101139A (bg) Съдържащи хетероатоми циклопентанопиридилоксазолидинони
BG103413A (bg) Производни на сулфиновата киселина, тяхното получаване и използване
BG104056A (bg) Триазолови съединения и използването им като допамин-d3-лиганди
BG104812A (bg) Нови дихидропиримидини
AU2002343557A1 (en) Substituted aryl 1,4-pyrazine derivatives
PL336580A1 (en) Fine-molecular compounds useful in treating inflammatory diseases
BG103310A (bg) Бензонафтиридини като бронхиални лечебни средства
IL130260A0 (en) 3-thiocarbamoylpyrazole derivatives as pesticides
IL138847A0 (en) New hydroxyindoles, their use as phosphodiesterase 4 inhibitors and method for producing same
BG103219A (bg) Бензамидинови производни и използването им като лекарствени средства с ltb4-антагонистично действие
BG103590A (bg) Пестицидни 1-арилпиразоли
BG101110A (bg) Заместени пиримидинови съединения и тяхното използване
BG102616A (bg) Заместени аза- и диазациклохептанови и циклооктанови производни и използването им
BG101105A (bg) Заместени бензамидини, тяхното получаване и използването им като лекарствени средства
BG104291A (bg) 3-заместени тетрахидропиридопиримидинонови производни, тяхното получаване и използване
BG102623A (bg) Нови производни на бензоилгуанидина, методи за тяхното получаване и приложението им за производството на ле- карствени средства
BG104232A (bg) Заместени 1,2,3,4,5,6-хексахидро-2,6-метано-3-бензазоцин- 10-оли, метод за тяхното получаване и приложението им като лекарствени средства
BG102770A (bg) Нови производни на карбоксилни киселини, тяхното получаване и използване
MX9700813A (es) Nuevos derivados 3-substituidos de 3h-2,3-benzodiazepina, su preparacion y su uso como medicamentos.
ES2185196T3 (es) Un procedimiento para la preparacion de tetraazamacrociclos.
TR200000371T2 (tr) 3-İkame edilen 3,4,5,7,- tetrahidro-pirrolo [3',4':4,5] tieno[2,3-D] pirimidin türevleri, üretimi ve 5HT-antagonistleri olarak kullanımları.
BG102771A (bg) Нови диарилметилиденфуранови производни, метод за тяхното получаване и използването им като лекарствени средства
ZA200005540B (en) New hydroxyindoles, their use as phosphodiestrase 4 inhibitors and method for producing same.