BG103684A - DERIVATIVES OF 2,3-DIHYDROFLUORO[3,2-b]PYRIDIN, METHOD FOR THEIR PREPARATION AND APPLICATION IN THERAPY - Google Patents
DERIVATIVES OF 2,3-DIHYDROFLUORO[3,2-b]PYRIDIN, METHOD FOR THEIR PREPARATION AND APPLICATION IN THERAPYInfo
- Publication number
- BG103684A BG103684A BG103684A BG10368499A BG103684A BG 103684 A BG103684 A BG 103684A BG 103684 A BG103684 A BG 103684A BG 10368499 A BG10368499 A BG 10368499A BG 103684 A BG103684 A BG 103684A
- Authority
- BG
- Bulgaria
- Prior art keywords
- alkyl group
- dihydrofluoro
- pyridin
- therapy
- derivatives
- Prior art date
Links
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 229960002715 nicotine Drugs 0.000 abstract 2
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 cyano, hydroxy Chemical group 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 210000005095 gastrointestinal system Anatomy 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9703395A FR2761072B1 (fr) | 1997-03-20 | 1997-03-20 | Derives de 2,3-dihydrofuro[3,2-b]pyridine, leur preparation et leur application en therapeutique |
| PCT/FR1998/000531 WO1998042713A1 (fr) | 1997-03-20 | 1998-03-17 | DERIVES DE 2,3-DIHYDROFURO[3,2-b]PYRIDINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG103684A true BG103684A (en) | 2000-06-30 |
Family
ID=9505006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG103684A BG103684A (en) | 1997-03-20 | 1999-08-24 | DERIVATIVES OF 2,3-DIHYDROFLUORO[3,2-b]PYRIDIN, METHOD FOR THEIR PREPARATION AND APPLICATION IN THERAPY |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6143761A (xx) |
| EP (1) | EP0971929A1 (xx) |
| JP (1) | JP2001518099A (xx) |
| KR (1) | KR20000076282A (xx) |
| CN (1) | CN1251105A (xx) |
| AR (1) | AR012097A1 (xx) |
| AU (1) | AU6924298A (xx) |
| BG (1) | BG103684A (xx) |
| BR (1) | BR9808346A (xx) |
| CA (1) | CA2282320A1 (xx) |
| CO (1) | CO4940417A1 (xx) |
| EE (1) | EE9900414A (xx) |
| FR (1) | FR2761072B1 (xx) |
| HU (1) | HUP0002335A3 (xx) |
| IL (1) | IL131254A0 (xx) |
| NO (1) | NO994527L (xx) |
| NZ (1) | NZ337566A (xx) |
| PL (1) | PL335759A1 (xx) |
| SK (1) | SK127699A3 (xx) |
| TR (1) | TR199902115T2 (xx) |
| WO (1) | WO1998042713A1 (xx) |
| ZA (1) | ZA982365B (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2790474B1 (fr) * | 1999-03-05 | 2001-04-06 | Synthelabo | Derives de pyridopyranoazepines, leur preparation et leur application en therapeutique |
| SE9902267D0 (sv) * | 1999-06-16 | 1999-06-16 | Astra Ab | New compounds |
| JP2005104838A (ja) * | 2003-01-09 | 2005-04-21 | Tanabe Seiyaku Co Ltd | 縮合フラン化合物 |
| EP1802258A4 (en) | 2004-09-13 | 2015-09-23 | Chrono Therapeutics Inc | BIOSYNCHRONE TRANSDERMAL MEDICINES |
| EP1977746B8 (en) | 2007-04-02 | 2014-09-24 | Parkinson's Institute | Methods and compositions for reduction of side effects of therapeutic treatments |
| WO2016123406A1 (en) | 2015-01-28 | 2016-08-04 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
| US9585867B2 (en) | 2015-08-06 | 2017-03-07 | Charles Everett Ankner | Cannabinod formulation for the sedation of a human or animal |
| CA3049529A1 (en) | 2017-01-06 | 2018-07-12 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
| US11596779B2 (en) | 2018-05-29 | 2023-03-07 | Morningside Venture Investments Limited | Drug delivery methods and systems |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT842178E (pt) * | 1995-07-28 | 2001-08-30 | Abbott Lab | Furopiridina tienopiridina pirrolopiridina e compostos relacionados de pirimidina piridazina e triazina uteis no controlo da transmissao sinaptica quimica |
-
1997
- 1997-03-20 FR FR9703395A patent/FR2761072B1/fr not_active Expired - Fee Related
-
1998
- 1998-03-17 HU HU0002335A patent/HUP0002335A3/hu unknown
- 1998-03-17 TR TR1999/02115T patent/TR199902115T2/xx unknown
- 1998-03-17 CA CA002282320A patent/CA2282320A1/en not_active Abandoned
- 1998-03-17 SK SK1276-99A patent/SK127699A3/sk unknown
- 1998-03-17 CN CN98803563A patent/CN1251105A/zh active Pending
- 1998-03-17 BR BR9808346-5A patent/BR9808346A/pt not_active IP Right Cessation
- 1998-03-17 WO PCT/FR1998/000531 patent/WO1998042713A1/fr not_active Application Discontinuation
- 1998-03-17 EP EP98914931A patent/EP0971929A1/fr not_active Withdrawn
- 1998-03-17 AU AU69242/98A patent/AU6924298A/en not_active Abandoned
- 1998-03-17 NZ NZ337566A patent/NZ337566A/xx unknown
- 1998-03-17 US US09/381,098 patent/US6143761A/en not_active Expired - Fee Related
- 1998-03-17 EE EEP199900414A patent/EE9900414A/xx unknown
- 1998-03-17 KR KR1019997008379A patent/KR20000076282A/ko not_active Application Discontinuation
- 1998-03-17 PL PL98335759A patent/PL335759A1/xx unknown
- 1998-03-17 IL IL13125498A patent/IL131254A0/xx unknown
- 1998-03-17 JP JP54444598A patent/JP2001518099A/ja active Pending
- 1998-03-18 AR ARP980101212A patent/AR012097A1/es unknown
- 1998-03-18 CO CO98015204A patent/CO4940417A1/es unknown
- 1998-03-19 ZA ZA982365A patent/ZA982365B/xx unknown
-
1999
- 1999-08-24 BG BG103684A patent/BG103684A/xx unknown
- 1999-09-17 NO NO994527A patent/NO994527L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL335759A1 (en) | 2000-05-22 |
| TR199902115T2 (xx) | 2000-01-21 |
| FR2761072B1 (fr) | 1999-04-23 |
| IL131254A0 (en) | 2001-01-28 |
| ZA982365B (en) | 1998-09-23 |
| CO4940417A1 (es) | 2000-07-24 |
| JP2001518099A (ja) | 2001-10-09 |
| NO994527D0 (no) | 1999-09-17 |
| HUP0002335A3 (en) | 2002-07-29 |
| CN1251105A (zh) | 2000-04-19 |
| NO994527L (no) | 1999-11-18 |
| EE9900414A (et) | 2000-04-17 |
| KR20000076282A (ko) | 2000-12-26 |
| WO1998042713A1 (fr) | 1998-10-01 |
| US6143761A (en) | 2000-11-07 |
| EP0971929A1 (fr) | 2000-01-19 |
| HUP0002335A2 (hu) | 2001-05-28 |
| AR012097A1 (es) | 2000-09-27 |
| AU6924298A (en) | 1998-10-20 |
| SK127699A3 (en) | 2000-05-16 |
| FR2761072A1 (fr) | 1998-09-25 |
| CA2282320A1 (en) | 1998-10-01 |
| BR9808346A (pt) | 2000-05-23 |
| NZ337566A (en) | 2000-09-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB9921150D0 (en) | Therapeutic agents | |
| BG104279A (en) | Derivatives of 2,3-diarylpyrazolo[1,5-b]pyridazins, their preparation and application as cyclooxygenase-2 (cox-2) inhibitors | |
| MY112232A (en) | Indole derivatives | |
| NZ512731A (en) | Tricyclic inhibitors of poly(ADP-ribose) polymerases | |
| MY118163A (en) | Aryl fused azapolycyclic compounds | |
| AU6607901A (en) | Azaindole derivatives, process for their preparation, and their use as antitumoragents | |
| BG101806A (en) | Indole derivatives as 5-ht receptor antagoniss | |
| NZ333706A (en) | Benzenesulfone derivatives and medicaments | |
| GB9927687D0 (en) | Therapeutic agents | |
| HUP9801340A1 (hu) | Triciklusos pirazolszármazékok és az azokat tartalmazó gyógyszerkészítmények | |
| BG102820A (en) | Substituted tetracyclic tetrahydrofurane derivatives | |
| NZ512981A (en) | Use of pyridazino[4,5-b]indole-1-acetamide derivatives for treating diseases related to the dysfunction of peripheral benzodiazepine receptors | |
| BG103684A (en) | DERIVATIVES OF 2,3-DIHYDROFLUORO[3,2-b]PYRIDIN, METHOD FOR THEIR PREPARATION AND APPLICATION IN THERAPY | |
| MX9806171A (es) | Derivados 2,3-benzodiazepina y sus usos como inhibidores del receptor-ampa. | |
| CA2252039A1 (en) | Isatin derivatives as acetylcholinesterase inhibitors and analgesics | |
| NO20000957L (no) | Forgrenede alkoksy-substituerte 2-aminopyridiner som NOS inhibitorer | |
| BG103301A (en) | Derivatives of 1h-pyrido(3,4-b)indol-4-carboxamide, method for their preparation and application as therapeutical means | |
| DE69840388D1 (de) | Camptothecin-analoge und verfahren zu ihrer herstellung | |
| NZ330974A (en) | Aminotetralin derivatives and pharmaceutical compositions thereof | |
| IL122974A (en) | Optionally substituted tetrahydro-1H-naph[1,2,3-de]isoquinoline and pharmaceutical compositions containing them | |
| UA66888C2 (uk) | 3-тетрагідропіридин-4-іл індоли, спосіб їх отримання та спосіб лікування психічних розладів | |
| BG99566A (en) | 4-quinoline derivatives with anti helicobacter activity | |
| NO973340L (no) | Anvendelse av 3,4-difenylkromaner til fremstilling av et farmasöytisk preparat for behandling eller profylakse av fedme | |
| DK1025101T3 (da) | Naphtho-imidazo[1,2-a]pyridinderivater, deres fremstilling og deres anvendelse ved behandlingen af sygdomme i centralnervesystemet | |
| MXPA98005355A (es) | Derivados de 5-[(heteroaril) alquil]-3 -oxo-pirido [1, 2-a]bencimidazol -4-carboxamida utiles en el tratamiento de trastornos del sistema nervioso central. |