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BG102222A - Използване на производни на сулфаминовата киселина, ацил сулфонамиди или сулфамоил карбамати за получаването на средство за понижаване на липопротеиновите нива - Google Patents

Използване на производни на сулфаминовата киселина, ацил сулфонамиди или сулфамоил карбамати за получаването на средство за понижаване на липопротеиновите нива

Info

Publication number
BG102222A
BG102222A BG102222A BG10222298A BG102222A BG 102222 A BG102222 A BG 102222A BG 102222 A BG102222 A BG 102222A BG 10222298 A BG10222298 A BG 10222298A BG 102222 A BG102222 A BG 102222A
Authority
BG
Bulgaria
Prior art keywords
sulphamoylcarbamates
acylsulphanomides
medicament
derivatives
preparation
Prior art date
Application number
BG102222A
Other languages
English (en)
Other versions
BG63863B1 (bg
Inventor
Brian KRAUSE
Original Assignee
Warner-Lambert Company Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company Llc filed Critical Warner-Lambert Company Llc
Publication of BG102222A publication Critical patent/BG102222A/bg
Publication of BG63863B1 publication Critical patent/BG63863B1/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Изобретението се отнася до ново терапевтично използване на съединения с формула, в която Х и Y означават кислород, сяра или (CR'R'')n, като n има стойност от 1 до 4, R е водород, алкил или бензил, R1и R2 означават фенил, заместен фенил, нафтил, заместен нафтил, аралкилна група, алкилна верига, адамантил или циклоалкилна група. Тези съединения се използват при цереброваскуларни заболявания, като удар, заболявания на периферната кръвоносна система и растеноза.
BG102222A 1995-08-04 1998-01-30 Използване на производни на сулфаминовата киселина, ацил сулфонамиди или сулфамоил карбамати за получаването на средство за понижаване на липопротеиновите нива BG63863B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US303195P 1995-08-04 1995-08-04
PCT/US1996/011366 WO1997005868A1 (en) 1995-08-04 1996-07-08 Use of sulfamic acid derivatives, acyl sulfonamides or sulfonyl carbamates for the manufacture of a medicament for lowering lipoprotein levels

Publications (2)

Publication Number Publication Date
BG102222A true BG102222A (bg) 1998-09-30
BG63863B1 BG63863B1 (bg) 2003-04-30

Family

ID=21703764

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102222A BG63863B1 (bg) 1995-08-04 1998-01-30 Използване на производни на сулфаминовата киселина, ацил сулфонамиди или сулфамоил карбамати за получаването на средство за понижаване на липопротеиновите нива

Country Status (27)

Country Link
US (1) US6117909A (bg)
EP (1) EP0841913B1 (bg)
JP (1) JPH11510184A (bg)
KR (1) KR19990036127A (bg)
CN (1) CN1192140A (bg)
AT (1) ATE232097T1 (bg)
AU (1) AU716255B2 (bg)
BG (1) BG63863B1 (bg)
CA (1) CA2221729A1 (bg)
CZ (1) CZ26198A3 (bg)
DE (1) DE69626118T2 (bg)
DK (1) DK0841913T3 (bg)
EA (1) EA002435B1 (bg)
EE (1) EE9800037A (bg)
ES (1) ES2191762T3 (bg)
GE (1) GEP20012511B (bg)
HR (1) HRP960341A2 (bg)
HU (1) HUP9900668A3 (bg)
IL (1) IL122247A0 (bg)
NO (1) NO980466D0 (bg)
NZ (1) NZ312571A (bg)
PL (1) PL185943B1 (bg)
PT (1) PT841913E (bg)
SK (1) SK12598A3 (bg)
UA (1) UA46030C2 (bg)
WO (1) WO1997005868A1 (bg)
ZA (1) ZA966617B (bg)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1584333A3 (en) * 1998-01-28 2009-04-29 Warner-Lambert Company LLC Use of acetylcoenzime A inhibitors for treating Alzheimer's disease
TR200100205T2 (tr) * 1998-07-21 2001-05-21 Warner-Lambert Company Aterosklerotik lezyonların tedavisi için ACAT ve MMP inhibitörlerinin birlikte uygulanması.
IT1303249B1 (it) * 1998-10-23 2000-11-06 Dompe Spa Alcune n-(2-aril-propionil)-solfonammidi e preparazionifarmaceutiche che le contengono.
KR20020050257A (ko) * 1999-11-05 2002-06-26 로즈 암스트롱, 크리스틴 에이. 트러트웨인 Acat 저해제에 의한 플라크 파열의 방지
CA2369967A1 (en) * 2001-02-12 2002-08-12 Joseph Anthony Cornicelli Methods of treating nuclear factor-kappa b mediated diseases and disorders
AR037097A1 (es) 2001-10-05 2004-10-20 Novartis Ag Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento
US6939224B2 (en) * 2002-03-12 2005-09-06 Igt Gaming device having varying risk player selections
US11498904B2 (en) 2017-11-14 2022-11-15 Merck Sharp & Dohme Llc Substituted biaryl compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
JP7269928B2 (ja) 2017-11-14 2023-05-09 メルク・シャープ・アンド・ドーム・エルエルシー インドールアミン 2,3-ジオキシゲナーゼ(ido)阻害剤としての新規の置換ビアリール化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5003106A (en) * 1983-07-19 1991-03-26 American Cyanamid Company Antiatherosclerotic ureas and thioureas
ATE116291T1 (de) * 1990-10-30 1995-01-15 Warner Lambert Co Oxysulfonylcarbamate.
US5245068A (en) * 1990-10-30 1993-09-14 Warner-Lambert Company Oxysulfonyl carbamates
IL101785A0 (en) * 1991-05-10 1992-12-30 Fujisawa Pharmaceutical Co Urea derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US5491172A (en) * 1993-05-14 1996-02-13 Warner-Lambert Company N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents
IL109431A (en) * 1993-05-14 2001-01-11 Warner Lambert Co Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds

Also Published As

Publication number Publication date
UA46030C2 (uk) 2002-05-15
EA002435B1 (ru) 2002-04-25
NZ312571A (en) 2000-07-28
IL122247A0 (en) 1998-04-05
DE69626118D1 (de) 2003-03-13
ATE232097T1 (de) 2003-02-15
HRP960341A2 (en) 1998-02-28
KR19990036127A (ko) 1999-05-25
BG63863B1 (bg) 2003-04-30
GEP20012511B (en) 2001-08-27
EA199800176A1 (ru) 1998-10-29
ES2191762T3 (es) 2003-09-16
EE9800037A (et) 1998-08-17
HUP9900668A2 (hu) 1999-06-28
WO1997005868A1 (en) 1997-02-20
JPH11510184A (ja) 1999-09-07
AU716255B2 (en) 2000-02-24
CN1192140A (zh) 1998-09-02
PL324908A1 (en) 1998-06-22
EP0841913B1 (en) 2003-02-05
EP0841913A1 (en) 1998-05-20
SK12598A3 (en) 1999-02-11
DK0841913T3 (da) 2003-05-05
PT841913E (pt) 2003-06-30
PL185943B1 (pl) 2003-09-30
AU6454196A (en) 1997-03-05
HUP9900668A3 (en) 2000-08-28
NO980466L (no) 1998-02-03
ZA966617B (en) 1997-02-18
CA2221729A1 (en) 1997-02-20
CZ26198A3 (cs) 1998-07-15
NO980466D0 (no) 1998-02-03
DE69626118T2 (de) 2003-11-27
US6117909A (en) 2000-09-12

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