BG102222A - Използване на производни на сулфаминовата киселина, ацил сулфонамиди или сулфамоил карбамати за получаването на средство за понижаване на липопротеиновите нива - Google Patents
Използване на производни на сулфаминовата киселина, ацил сулфонамиди или сулфамоил карбамати за получаването на средство за понижаване на липопротеиновите ниваInfo
- Publication number
- BG102222A BG102222A BG102222A BG10222298A BG102222A BG 102222 A BG102222 A BG 102222A BG 102222 A BG102222 A BG 102222A BG 10222298 A BG10222298 A BG 10222298A BG 102222 A BG102222 A BG 102222A
- Authority
- BG
- Bulgaria
- Prior art keywords
- sulphamoylcarbamates
- acylsulphanomides
- medicament
- derivatives
- preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Изобретението се отнася до ново терапевтично използване на съединения с формула, в която Х и Y означават кислород, сяра или (CR'R'')n, като n има стойност от 1 до 4, R е водород, алкил или бензил, R1и R2 означават фенил, заместен фенил, нафтил, заместен нафтил, аралкилна група, алкилна верига, адамантил или циклоалкилна група. Тези съединения се използват при цереброваскуларни заболявания, като удар, заболявания на периферната кръвоносна система и растеноза.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US303195P | 1995-08-04 | 1995-08-04 | |
PCT/US1996/011366 WO1997005868A1 (en) | 1995-08-04 | 1996-07-08 | Use of sulfamic acid derivatives, acyl sulfonamides or sulfonyl carbamates for the manufacture of a medicament for lowering lipoprotein levels |
Publications (2)
Publication Number | Publication Date |
---|---|
BG102222A true BG102222A (bg) | 1998-09-30 |
BG63863B1 BG63863B1 (bg) | 2003-04-30 |
Family
ID=21703764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG102222A BG63863B1 (bg) | 1995-08-04 | 1998-01-30 | Използване на производни на сулфаминовата киселина, ацил сулфонамиди или сулфамоил карбамати за получаването на средство за понижаване на липопротеиновите нива |
Country Status (27)
Country | Link |
---|---|
US (1) | US6117909A (bg) |
EP (1) | EP0841913B1 (bg) |
JP (1) | JPH11510184A (bg) |
KR (1) | KR19990036127A (bg) |
CN (1) | CN1192140A (bg) |
AT (1) | ATE232097T1 (bg) |
AU (1) | AU716255B2 (bg) |
BG (1) | BG63863B1 (bg) |
CA (1) | CA2221729A1 (bg) |
CZ (1) | CZ26198A3 (bg) |
DE (1) | DE69626118T2 (bg) |
DK (1) | DK0841913T3 (bg) |
EA (1) | EA002435B1 (bg) |
EE (1) | EE9800037A (bg) |
ES (1) | ES2191762T3 (bg) |
GE (1) | GEP20012511B (bg) |
HR (1) | HRP960341A2 (bg) |
HU (1) | HUP9900668A3 (bg) |
IL (1) | IL122247A0 (bg) |
NO (1) | NO980466D0 (bg) |
NZ (1) | NZ312571A (bg) |
PL (1) | PL185943B1 (bg) |
PT (1) | PT841913E (bg) |
SK (1) | SK12598A3 (bg) |
UA (1) | UA46030C2 (bg) |
WO (1) | WO1997005868A1 (bg) |
ZA (1) | ZA966617B (bg) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1584333A3 (en) * | 1998-01-28 | 2009-04-29 | Warner-Lambert Company LLC | Use of acetylcoenzime A inhibitors for treating Alzheimer's disease |
TR200100205T2 (tr) * | 1998-07-21 | 2001-05-21 | Warner-Lambert Company | Aterosklerotik lezyonların tedavisi için ACAT ve MMP inhibitörlerinin birlikte uygulanması. |
IT1303249B1 (it) * | 1998-10-23 | 2000-11-06 | Dompe Spa | Alcune n-(2-aril-propionil)-solfonammidi e preparazionifarmaceutiche che le contengono. |
KR20020050257A (ko) * | 1999-11-05 | 2002-06-26 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | Acat 저해제에 의한 플라크 파열의 방지 |
CA2369967A1 (en) * | 2001-02-12 | 2002-08-12 | Joseph Anthony Cornicelli | Methods of treating nuclear factor-kappa b mediated diseases and disorders |
AR037097A1 (es) | 2001-10-05 | 2004-10-20 | Novartis Ag | Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento |
US6939224B2 (en) * | 2002-03-12 | 2005-09-06 | Igt | Gaming device having varying risk player selections |
US11498904B2 (en) | 2017-11-14 | 2022-11-15 | Merck Sharp & Dohme Llc | Substituted biaryl compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors |
JP7269928B2 (ja) | 2017-11-14 | 2023-05-09 | メルク・シャープ・アンド・ドーム・エルエルシー | インドールアミン 2,3-ジオキシゲナーゼ(ido)阻害剤としての新規の置換ビアリール化合物 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5003106A (en) * | 1983-07-19 | 1991-03-26 | American Cyanamid Company | Antiatherosclerotic ureas and thioureas |
ATE116291T1 (de) * | 1990-10-30 | 1995-01-15 | Warner Lambert Co | Oxysulfonylcarbamate. |
US5245068A (en) * | 1990-10-30 | 1993-09-14 | Warner-Lambert Company | Oxysulfonyl carbamates |
IL101785A0 (en) * | 1991-05-10 | 1992-12-30 | Fujisawa Pharmaceutical Co | Urea derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
US5491172A (en) * | 1993-05-14 | 1996-02-13 | Warner-Lambert Company | N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents |
IL109431A (en) * | 1993-05-14 | 2001-01-11 | Warner Lambert Co | Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds |
-
1996
- 1996-07-08 KR KR1019980700795A patent/KR19990036127A/ko not_active Application Discontinuation
- 1996-07-08 SK SK125-98A patent/SK12598A3/sk unknown
- 1996-07-08 US US09/000,296 patent/US6117909A/en not_active Expired - Fee Related
- 1996-07-08 PT PT96923687T patent/PT841913E/pt unknown
- 1996-07-08 EP EP96923687A patent/EP0841913B1/en not_active Expired - Lifetime
- 1996-07-08 WO PCT/US1996/011366 patent/WO1997005868A1/en not_active Application Discontinuation
- 1996-07-08 GE GEAP19964165A patent/GEP20012511B/en unknown
- 1996-07-08 NZ NZ312571A patent/NZ312571A/en unknown
- 1996-07-08 HU HU9900668A patent/HUP9900668A3/hu unknown
- 1996-07-08 EE EE9800037A patent/EE9800037A/xx unknown
- 1996-07-08 JP JP9508427A patent/JPH11510184A/ja active Pending
- 1996-07-08 DK DK96923687T patent/DK0841913T3/da active
- 1996-07-08 CN CN96196033A patent/CN1192140A/zh active Pending
- 1996-07-08 IL IL12224796A patent/IL122247A0/xx unknown
- 1996-07-08 CZ CZ98261A patent/CZ26198A3/cs unknown
- 1996-07-08 DE DE69626118T patent/DE69626118T2/de not_active Expired - Fee Related
- 1996-07-08 ES ES96923687T patent/ES2191762T3/es not_active Expired - Lifetime
- 1996-07-08 AT AT96923687T patent/ATE232097T1/de not_active IP Right Cessation
- 1996-07-08 AU AU64541/96A patent/AU716255B2/en not_active Ceased
- 1996-07-08 CA CA002221729A patent/CA2221729A1/en not_active Abandoned
- 1996-07-08 PL PL96324908A patent/PL185943B1/pl unknown
- 1996-07-08 EA EA199800176A patent/EA002435B1/ru not_active IP Right Cessation
- 1996-07-16 HR HR60/003,031A patent/HRP960341A2/hr not_active Application Discontinuation
- 1996-08-02 ZA ZA9606617A patent/ZA966617B/xx unknown
- 1996-08-07 UA UA97126430A patent/UA46030C2/uk unknown
-
1998
- 1998-01-30 BG BG102222A patent/BG63863B1/bg unknown
- 1998-02-03 NO NO980466A patent/NO980466D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
UA46030C2 (uk) | 2002-05-15 |
EA002435B1 (ru) | 2002-04-25 |
NZ312571A (en) | 2000-07-28 |
IL122247A0 (en) | 1998-04-05 |
DE69626118D1 (de) | 2003-03-13 |
ATE232097T1 (de) | 2003-02-15 |
HRP960341A2 (en) | 1998-02-28 |
KR19990036127A (ko) | 1999-05-25 |
BG63863B1 (bg) | 2003-04-30 |
GEP20012511B (en) | 2001-08-27 |
EA199800176A1 (ru) | 1998-10-29 |
ES2191762T3 (es) | 2003-09-16 |
EE9800037A (et) | 1998-08-17 |
HUP9900668A2 (hu) | 1999-06-28 |
WO1997005868A1 (en) | 1997-02-20 |
JPH11510184A (ja) | 1999-09-07 |
AU716255B2 (en) | 2000-02-24 |
CN1192140A (zh) | 1998-09-02 |
PL324908A1 (en) | 1998-06-22 |
EP0841913B1 (en) | 2003-02-05 |
EP0841913A1 (en) | 1998-05-20 |
SK12598A3 (en) | 1999-02-11 |
DK0841913T3 (da) | 2003-05-05 |
PT841913E (pt) | 2003-06-30 |
PL185943B1 (pl) | 2003-09-30 |
AU6454196A (en) | 1997-03-05 |
HUP9900668A3 (en) | 2000-08-28 |
NO980466L (no) | 1998-02-03 |
ZA966617B (en) | 1997-02-18 |
CA2221729A1 (en) | 1997-02-20 |
CZ26198A3 (cs) | 1998-07-15 |
NO980466D0 (no) | 1998-02-03 |
DE69626118T2 (de) | 2003-11-27 |
US6117909A (en) | 2000-09-12 |
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