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BG101570A - Производни на еритромицин а 9-0-оксим, притежаващи антибиотична активност - Google Patents

Производни на еритромицин а 9-0-оксим, притежаващи антибиотична активност

Info

Publication number
BG101570A
BG101570A BG101570A BG10157097A BG101570A BG 101570 A BG101570 A BG 101570A BG 101570 A BG101570 A BG 101570A BG 10157097 A BG10157097 A BG 10157097A BG 101570 A BG101570 A BG 101570A
Authority
BG
Bulgaria
Prior art keywords
erythromycin
oxime
derivatives
antibiotic activity
compounds
Prior art date
Application number
BG101570A
Other languages
English (en)
Other versions
BG63261B1 (bg
Inventor
Franco Pellacini
Giovanna Schioppacassi
Enrico Albini
Daniela Botta
Stefano Romagnano
Francesco Santangelo
Original Assignee
Zambon Group S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Group S.P.A. filed Critical Zambon Group S.P.A.
Publication of BG101570A publication Critical patent/BG101570A/bg
Publication of BG63261B1 publication Critical patent/BG63261B1/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Изобретението се отнася до съединения с формула, в която А, R1, R2, M, n, m и r имат посочените в описанието значения, до методи за получаването им и фармацевтични състави, които ги съдържат като активни съставки. Съединенията са приложими при лечението на инфекциозни заболявания.
BG101570A 1994-12-13 1997-06-05 Производни на еритромицин а 9-0-оксим, притежаващи антибиотична активност BG63261B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT94MI002496A IT1276901B1 (it) 1994-12-13 1994-12-13 Derivati dell'eritromicina a 9-0-ossina dotati di attivita' antibiotica
PCT/EP1995/004815 WO1996018633A1 (en) 1994-12-13 1995-12-07 Erythromycin a 9-0-oxime derivatives endowed with antibiotic activity

Publications (2)

Publication Number Publication Date
BG101570A true BG101570A (bg) 1998-02-27
BG63261B1 BG63261B1 (bg) 2001-07-31

Family

ID=11369979

Family Applications (1)

Application Number Title Priority Date Filing Date
BG101570A BG63261B1 (bg) 1994-12-13 1997-06-05 Производни на еритромицин а 9-0-оксим, притежаващи антибиотична активност

Country Status (35)

Country Link
US (1) US5847092A (bg)
EP (1) EP0797579B1 (bg)
JP (1) JPH10510520A (bg)
KR (1) KR100367559B1 (bg)
CN (1) CN1046535C (bg)
AP (1) AP739A (bg)
AT (1) ATE190620T1 (bg)
AU (1) AU690791B2 (bg)
BG (1) BG63261B1 (bg)
BR (1) BR9510015A (bg)
CA (1) CA2207029A1 (bg)
CZ (1) CZ289943B6 (bg)
DE (1) DE69515694T2 (bg)
DK (1) DK0797579T3 (bg)
EE (1) EE03401B1 (bg)
ES (1) ES2144154T3 (bg)
FI (1) FI972493L (bg)
GE (1) GEP20012391B (bg)
GR (1) GR3033622T3 (bg)
HU (1) HU220631B1 (bg)
IT (1) IT1276901B1 (bg)
LT (1) LT4276B (bg)
LV (1) LV11898B (bg)
MD (1) MD1788G2 (bg)
NO (1) NO309816B1 (bg)
NZ (1) NZ297446A (bg)
OA (1) OA10491A (bg)
PL (1) PL182053B1 (bg)
PT (1) PT797579E (bg)
RO (1) RO116282B1 (bg)
RU (1) RU2152951C1 (bg)
SI (1) SI9520124A (bg)
TJ (1) TJ306B (bg)
UA (1) UA48958C2 (bg)
WO (1) WO1996018633A1 (bg)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1290447B1 (it) * 1997-03-28 1998-12-03 Zambon Spa Derivati 1,3-ossatiolanici ad attivita' antivirale
IT1301968B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Derivati di eritromicina ad attivita' antibiotica
IT1301967B1 (it) * 1998-07-30 2000-07-20 Zambon Spa Derivato di eritromicina ad attivita' antibiotica
IT1306205B1 (it) * 1999-01-15 2001-05-30 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
US6638908B1 (en) 2000-08-09 2003-10-28 Yale University Crystals of the large ribosomal subunit
US6947844B2 (en) 2000-08-09 2005-09-20 Yale University Modulators of ribosomal function and identification thereof
IL151012A0 (en) 2001-08-03 2003-02-12 Ribosomes Structure And Protei Ribosomes structure and protein synthesis inhibitors
US6952650B2 (en) 2001-08-03 2005-10-04 Yale University Modulators of ribosomal function and identification thereof
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
US7091196B2 (en) 2002-09-26 2006-08-15 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using same
EP2716647A3 (en) 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2473525A1 (fr) * 1980-01-11 1981-07-17 Roussel Uclaf Nouvelles oximes derivees de l'erythromycine, leur procede de preparation et leur application comme medicaments
GB8521402D0 (en) 1985-08-28 1985-10-02 Beecham Group Plc Chemical compounds
US4740502A (en) * 1986-06-20 1988-04-26 Abbott Laboratories Semisynthetic erythromycin antibiotics
EP0284203A3 (en) 1987-02-24 1989-11-02 Beecham Group Plc Erythromycin derivatives, process for their preparation and their pharmaceutical use
US5302705A (en) * 1989-10-07 1994-04-12 Taisho Pharmaceutical Co., Ltd. 6-O-methylerythromycin a oxime derivatives
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
BG63261B1 (bg) 2001-07-31
OA10491A (en) 2002-04-10
DK0797579T3 (da) 2000-06-05
ITMI942496A1 (it) 1996-06-13
RU2152951C1 (ru) 2000-07-20
HUT77126A (hu) 1998-03-02
SI9520124A (sl) 1998-04-30
GR3033622T3 (en) 2000-10-31
FI972493A0 (fi) 1997-06-12
ES2144154T3 (es) 2000-06-01
EE9700124A (et) 1997-12-15
TJ306B (en) 2001-08-06
IT1276901B1 (it) 1997-11-03
ATE190620T1 (de) 2000-04-15
MD1788F2 (en) 2001-11-30
MD1788G2 (ro) 2002-05-31
GEP20012391B (en) 2001-03-25
CN1046535C (zh) 1999-11-17
PT797579E (pt) 2000-08-31
NZ297446A (en) 1999-06-29
AU690791B2 (en) 1998-04-30
LV11898A (lv) 1997-12-20
AP9700989A0 (en) 1997-07-31
NO972702D0 (no) 1997-06-12
PL182053B1 (pl) 2001-10-31
AP739A (en) 1999-03-24
MX9704253A (es) 1997-09-30
HU220631B1 (hu) 2002-03-28
LT97116A (en) 1997-10-27
CA2207029A1 (en) 1996-06-20
NO309816B1 (no) 2001-04-02
RO116282B1 (ro) 2000-12-29
WO1996018633A1 (en) 1996-06-20
EP0797579B1 (en) 2000-03-15
CZ289943B6 (cs) 2002-04-17
ITMI942496A0 (it) 1994-12-13
FI972493L (fi) 1997-06-12
AU4260396A (en) 1996-07-03
MD970243A (en) 1999-05-31
EP0797579A1 (en) 1997-10-01
UA48958C2 (uk) 2002-09-16
LT4276B (lt) 1998-01-26
US5847092A (en) 1998-12-08
DE69515694T2 (de) 2000-10-26
LV11898B (en) 1998-03-20
JPH10510520A (ja) 1998-10-13
BR9510015A (pt) 1997-10-28
PL320688A1 (en) 1997-10-27
DE69515694D1 (de) 2000-04-20
CN1169727A (zh) 1998-01-07
KR100367559B1 (ko) 2003-04-21
NO972702L (no) 1997-08-13
CZ178697A3 (en) 1997-12-17
EE03401B1 (et) 2001-04-16

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