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BE901737A - Composition pharmaceutique pour le traitement de l'ischemie myocardique aigue. - Google Patents

Composition pharmaceutique pour le traitement de l'ischemie myocardique aigue.

Info

Publication number
BE901737A
BE901737A BE0/214518A BE214518A BE901737A BE 901737 A BE901737 A BE 901737A BE 0/214518 A BE0/214518 A BE 0/214518A BE 214518 A BE214518 A BE 214518A BE 901737 A BE901737 A BE 901737A
Authority
BE
Belgium
Prior art keywords
treatment
pharmaceutical composition
myocardial ischemia
acute myocardial
polydeoxyribonucleotoide
Prior art date
Application number
BE0/214518A
Other languages
English (en)
Inventor
G Prino
M Mantovani
R Niada
Original Assignee
Crinos Industria Farmaco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crinos Industria Farmaco filed Critical Crinos Industria Farmaco
Publication of BE901737A publication Critical patent/BE901737A/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

Compositions pour le traitement des états aigus d'ischémie et d'infarctus du myocarde comprenant comme ingrédient actif du défibrotide, un polydésoxyribonucléotoide obtenu par extraction à partir d'organes d'animaux, en combinaisonavec des véhicules et excipients usuels.
BE0/214518A 1984-02-16 1985-02-14 Composition pharmaceutique pour le traitement de l'ischemie myocardique aigue. BE901737A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8419645A IT1206341B (it) 1984-02-16 1984-02-16 Composizione farmaceutica per il trattamento dell'ischemia acuta del miocardio.

Publications (1)

Publication Number Publication Date
BE901737A true BE901737A (fr) 1985-05-29

Family

ID=11160049

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/214518A BE901737A (fr) 1984-02-16 1985-02-14 Composition pharmaceutique pour le traitement de l'ischemie myocardique aigue.

Country Status (9)

Country Link
US (1) US4693995A (fr)
EP (1) EP0152148B1 (fr)
JP (1) JPH0649651B2 (fr)
AT (1) ATE76296T1 (fr)
AU (1) AU585495B2 (fr)
BE (1) BE901737A (fr)
CH (1) CH662509A5 (fr)
DE (1) DE3505359C2 (fr)
IT (1) IT1206341B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1170214B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per la cura delle arteriopatie periferiche
IT1190313B (it) * 1986-04-17 1988-02-16 Crinos Industria Farmaco Procedimento per l'ottenimento di polidesossiribonucleotidi chimicamente definiti e riproducibili e prodotto farmacologicamente attivo risultante
DE3782427T2 (de) * 1986-10-06 1996-07-18 Univ Virginia Verwendung einer adenosin, hypoxanthin und ribose enthaltender lösung zur schonung des herzens während chirurgischer eingriffe.
IT1223322B (it) * 1987-10-23 1990-09-19 Crinos Industria Farmaco Metodo per prevenire la formazione di coaguli sanguigni nel circuito extracorporeo di apparecchi di dialisi a composizione utile per esso
IT1231509B (it) * 1989-09-07 1991-12-07 Crinos Industria Farmaco Composizione farmceutica ad uso topico per la terapia della fragilita' capillare.
US6699985B2 (en) * 1991-08-21 2004-03-02 Arsinur Burcoglu Method of treating HIV infection and related secondary infections thereof
US5624912A (en) * 1991-08-21 1997-04-29 Burcoglu; Arsinur Method of treating HIV infection and related secondary infections with defibrotide
US5977083A (en) * 1991-08-21 1999-11-02 Burcoglu; Arsinur Method for using polynucleotides, oligonucleotides and derivatives thereof to treat various disease states
IT1252174B (it) * 1991-12-09 1995-06-05 Crinos Industria Farmaco Oligodesossimibonucleotidi ad attivita' antiischemica e procedimenti per il loro ottenimento
CA2153778C (fr) * 1993-01-13 2004-07-06 Arsinur Burcoglu Methode d'utilisation de polynucleotides, d'oligonucleotides et de leurs derives pour traiter divers etats maladifs
US5852000A (en) * 1993-08-25 1998-12-22 Otsuka Pharmaceutical Factory, Inc. Cardiac rehabilitation agent
WO1995005832A1 (fr) * 1993-08-25 1995-03-02 Otsuka Pharmaceutical Factory, Inc. Analeptique des fonctions cardiaques
WO1998048843A1 (fr) * 1997-04-28 1998-11-05 Arsinur Burcoglu Traitement de l'infection par vih et de ses infections opportunistes
US7252818B2 (en) * 1998-07-24 2007-08-07 Cardiovascular Biotherapeutics, Inc. Method of producing biologically active human acidic fibroblast growth factor and its use in promoting angiogenesis
EP1147777A1 (fr) 2000-04-18 2001-10-24 Crinos Industria Farmacobiologica S.p.A. Combinaison de Defibrotide et de G-CSF et son utilisation pour activer les cellules progénitrices haematopoiétiques
EP1325962A1 (fr) * 2001-12-17 2003-07-09 Gentium S.p.A. Procédé pour la détermination de l'activité biologique de la defibrotide
EP1495702A1 (fr) 2003-07-10 2005-01-12 Nestec S.A. Dispositif pour l'extraction d'une capsule
ITMI20031714A1 (it) * 2003-09-05 2005-03-06 Gentium Spa Formazioni ad azione antitumorale.
JP5714203B2 (ja) * 2005-03-03 2015-05-07 ゲンチウム エスピーエー 血管新生依存性腫瘍を治療するためのデフィブロチドおよび／またはオリゴデオキシリボヌクレオチド
EP1872787A1 (fr) * 2006-06-27 2008-01-02 Gentium S.p.A. Utilisation de defibrotide pour l'inhibition de l'heparanase
EP1982722A1 (fr) * 2007-04-16 2008-10-22 Gentium S.p.A. Utilisation de oligotide pour le traitement de maladies rénales
EP2103689A1 (fr) * 2008-03-19 2009-09-23 Gentium S.p.A. Oligonucléotides phosphodiesters synthétiques et leurs utilisations thérapeutiques
IT1406068B1 (it) 2010-07-22 2014-02-06 Medestea Int Spa Polidesossiribonucleotidi (pdrn) per l'impiego nel trattamento di condizioni di acidosi e composizioni a base di polidesossiribonucleotidi per il suddetto impiego
DE102010039631A1 (de) 2010-08-22 2012-02-23 Ulrich Schubert Pharmazeutische Zusammensetzungen mit immunmodulatorischen Eigenschaften
CN107007617A (zh) 2010-11-12 2017-08-04 真蒂奥姆责任有限公司 去纤维蛋白多核苷酸用于预防和/或治疗移植物抗宿主病(gvhd)
IN2014DN10584A (fr) 2012-06-22 2015-08-28 Gentium Spa
EP3026122A1 (fr) 2014-11-27 2016-06-01 Gentium S.p.A. Procédé à base cellulaire pour déterminer la puissance de défibrotide
SG11202000952PA (en) 2017-08-03 2020-02-27 Jazz Pharmaceuticals Ireland Ltd Formulations comprising a nucleic acid in a high concentration
MX2020010689A (es) 2018-04-12 2021-01-20 Jazz Pharmaceuticals Inc Defibrotida para la prevencion y tratamiento del sindrome de liberacion de citocinas y la neurotoxicidad asociada con la inmunodeplecion.
WO2020118165A1 (fr) 2018-12-07 2020-06-11 Jazz Pharmaceuticals Ireland Limited Administration sous-cutanée de formulations à haute concentration
EP4110287A1 (fr) 2020-02-28 2023-01-04 Jazz Pharmaceuticals Ireland Limited Administration de formulations de faible viscosité
EP4135717A1 (fr) 2020-04-17 2023-02-22 Jazz Pharmaceuticals Ireland Limited Traitement de défibrotide pour la prévention d'un rejet et d'une lésion d'organe
WO2022234101A1 (fr) 2021-05-06 2022-11-10 Jazz Pharmaceuticals Ireland Limited Défibrotide pour le traitement et la prévention du syndrome de détresse respiratoire aiguë

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3899481A (en) * 1970-11-03 1975-08-12 Crinos Industria Farmaco Process for the controlled partial degradation of deoxyribonucleic acid extracted from animal organs
IT1043823B (it) * 1970-11-03 1980-02-29 Prephar Procedimento per l estrazione di acidi nucleici da organi animali
DE2154279A1 (de) * 1970-11-03 1972-05-25 Crinos Industria Farmaco Medikamente für das fibrinolytische System

Also Published As

Publication number Publication date
DE3505359C2 (de) 1994-01-20
US4693995A (en) 1987-09-15
JPS60188323A (ja) 1985-09-25
JPH0649651B2 (ja) 1994-06-29
EP0152148A2 (fr) 1985-08-21
CH662509A5 (it) 1987-10-15
EP0152148A3 (en) 1987-04-29
EP0152148B1 (fr) 1992-05-20
AU585495B2 (en) 1989-06-22
DE3505359A1 (de) 1985-08-22
IT8419645A0 (it) 1984-02-16
ATE76296T1 (de) 1992-06-15
IT1206341B (it) 1989-04-14
AU3878785A (en) 1985-08-22

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: CRINOS INDUSTRIA FARMACOBIOLOGICA S.P.A.

Effective date: 19980228