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BE894350A - NOVEL DERIVATIVES OF N "-CYANO N-OXYDO-1 PYRIDINIO-4 GUANIDINE N'-SUBSTITUEE USEFUL AS ANTIHYPERTENSIVE DRUGS AND PROCESS FOR THEIR PREPARATION - Google Patents

NOVEL DERIVATIVES OF N "-CYANO N-OXYDO-1 PYRIDINIO-4 GUANIDINE N'-SUBSTITUEE USEFUL AS ANTIHYPERTENSIVE DRUGS AND PROCESS FOR THEIR PREPARATION

Info

Publication number
BE894350A
BE894350A BE0/208978A BE208978A BE894350A BE 894350 A BE894350 A BE 894350A BE 0/208978 A BE0/208978 A BE 0/208978A BE 208978 A BE208978 A BE 208978A BE 894350 A BE894350 A BE 894350A
Authority
BE
Belgium
Prior art keywords
substituee
oxydo
pyridinio
guanidine
cyano
Prior art date
Application number
BE0/208978A
Other languages
French (fr)
Inventor
H J Petersen
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of BE894350A publication Critical patent/BE894350A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
BE0/208978A 1981-09-10 1982-09-09 NOVEL DERIVATIVES OF N "-CYANO N-OXYDO-1 PYRIDINIO-4 GUANIDINE N'-SUBSTITUEE USEFUL AS ANTIHYPERTENSIVE DRUGS AND PROCESS FOR THEIR PREPARATION BE894350A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8127367 1981-09-10

Publications (1)

Publication Number Publication Date
BE894350A true BE894350A (en) 1983-03-09

Family

ID=10524416

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/208978A BE894350A (en) 1981-09-10 1982-09-09 NOVEL DERIVATIVES OF N "-CYANO N-OXYDO-1 PYRIDINIO-4 GUANIDINE N'-SUBSTITUEE USEFUL AS ANTIHYPERTENSIVE DRUGS AND PROCESS FOR THEIR PREPARATION

Country Status (16)

Country Link
JP (1) JPS5857363A (en)
BE (1) BE894350A (en)
CA (1) CA1177080A (en)
CH (1) CH655500B (en)
DE (1) DE3233380A1 (en)
DK (1) DK157923C (en)
FR (1) FR2512447B1 (en)
GB (1) GB2105331B (en)
GR (1) GR77009B (en)
IE (1) IE54196B1 (en)
IT (1) IT1156515B (en)
LU (1) LU84375A1 (en)
NL (1) NL8203214A (en)
PH (1) PH18596A (en)
SE (1) SE441357B (en)
ZA (1) ZA825997B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5371086A (en) * 1991-03-15 1994-12-06 The Green Cross Corporation Aminopyridine compounds
JPH05294935A (en) * 1991-03-15 1993-11-09 Green Cross Corp:The Aminopyridine compound
EP1917245A1 (en) 2005-08-21 2008-05-07 Abbott GmbH & Co. KG Heterocyclic compounds and their use as binding partners for 5-ht5 receptors
EP1917244A2 (en) 2005-08-24 2008-05-07 Abbott GmbH & Co. KG Hetaryl-substituted guanidine compounds and use thereof as binding partners for 5-ht5-receptors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3074955A (en) * 1960-11-30 1963-01-22 Us Vitamin Pharm Corp Pyridylalkyl dicyandiamides and guanylureas
US3329569A (en) * 1962-07-31 1967-07-04 Smith Kline French Lab Hypotensive compositions and methods of producing hypotension
FR2043491A1 (en) * 1969-05-30 1971-02-19 Ugine Kuhlmann Alpha-pyrid-4'-yl-benzylidene-aminoguani- - dines useful as hypotensives and spasmoly-tics
GB1489879A (en) * 1974-12-20 1977-10-26 Leo Pharm Prod Ltd N'-cyano-n'-3-pyridylguanidines
NL8000869A (en) * 1979-02-16 1980-08-19 Eisai Co Ltd CYANOGUANIDINE DERIVATIVES AND METHOD FOR THE PREPARATION THEREOF.

Also Published As

Publication number Publication date
IT1156515B (en) 1987-02-04
JPS5857363A (en) 1983-04-05
DK398882A (en) 1983-03-11
CA1177080A (en) 1984-10-30
FR2512447B1 (en) 1985-11-22
NL8203214A (en) 1983-04-05
IE821918L (en) 1983-03-10
SE8205107D0 (en) 1982-09-08
PH18596A (en) 1985-08-15
SE441357B (en) 1985-09-30
ZA825997B (en) 1983-07-27
DE3233380A1 (en) 1983-03-17
SE8205107L (en) 1983-03-11
GB2105331A (en) 1983-03-23
GB2105331B (en) 1985-05-01
FR2512447A1 (en) 1983-03-11
IT8268075A0 (en) 1982-09-09
GR77009B (en) 1984-09-04
CH655500B (en) 1986-04-30
DK157923C (en) 1990-08-06
IE54196B1 (en) 1989-07-19
LU84375A1 (en) 1983-06-07
DK157923B (en) 1990-03-05

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: LEO PHARMACEUTICAL PRODUCTS LTD A/S (LOVENS KEMIS

Effective date: 19900930