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BE879494A - Procede de production de l'oxymorphone - Google Patents

Procede de production de l'oxymorphone

Info

Publication number
BE879494A
BE879494A BE0/197710A BE197710A BE879494A BE 879494 A BE879494 A BE 879494A BE 0/197710 A BE0/197710 A BE 0/197710A BE 197710 A BE197710 A BE 197710A BE 879494 A BE879494 A BE 879494A
Authority
BE
Belgium
Prior art keywords
oxymorphone
production process
production
oxymorphone production
Prior art date
Application number
BE0/197710A
Other languages
English (en)
Inventor
M Wilson
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of BE879494A publication Critical patent/BE879494A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Polarising Elements (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE0/197710A 1978-10-19 1979-10-18 Procede de production de l'oxymorphone BE879494A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95305678A 1978-10-19 1978-10-19

Publications (1)

Publication Number Publication Date
BE879494A true BE879494A (fr) 1980-02-15

Family

ID=25493512

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/197710A BE879494A (fr) 1978-10-19 1979-10-18 Procede de production de l'oxymorphone

Country Status (16)

Country Link
JP (1) JPS55501025A (fr)
AU (1) AU5189779A (fr)
BE (1) BE879494A (fr)
CA (1) CA1108132A (fr)
CS (1) CS211364B2 (fr)
DK (1) DK258280A (fr)
ES (1) ES485154A1 (fr)
FI (1) FI793235A (fr)
FR (1) FR2439201A1 (fr)
GB (1) GB2049680A (fr)
IL (1) IL58489A0 (fr)
IT (1) IT7969032A0 (fr)
NL (1) NL7920126A (fr)
NO (1) NO793297L (fr)
SE (1) SE8004454L (fr)
WO (1) WO1980000841A1 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795813A (en) * 1981-08-17 1989-01-03 The Florida Board Of Regents On Behalf Of The Florida State University Synthesis of derivatives of codeine and other 3-O-alkylmorphines
US5668285A (en) * 1986-10-31 1997-09-16 The United States Of America As Represented By The Department Of Health And Human Services Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
FR2636330B1 (fr) * 1988-09-13 1990-11-30 Sanofi Sa Procede de preparation de derives de morphinane
WO1991005768A1 (fr) * 1989-10-16 1991-05-02 The United States Of America, Represented By The Secretary, United States Department Of Commerce Synthese totale d'enantiomeres et de derives de northebaine, normorphine, neuroxymorphone par des intermediaires n-nor
DE60219478T2 (de) 2001-07-06 2008-01-03 Endo Pharmaceuticals Inc. Orale gabe von 6-hydroxy-oxymorphon als analgetikum
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
CN101395159A (zh) 2006-03-02 2009-03-25 马林克罗特公司 制备含有低含量α,β-不饱和酮化合物的吗啡烷-6-酮产物的方法
JP5774853B2 (ja) 2008-01-25 2015-09-09 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 医薬投薬形
BRPI0912014A2 (pt) 2008-05-09 2019-03-06 Grünenthal GmbH processo para a preparação de uma formulação em pó intermediária e uma forma de dosagem sólida final sob uso de uma etapa de congelamento por atomização
MX2012000317A (es) 2009-07-22 2012-02-08 Gruenenthal Gmbh Forma de dosificacion de liberacion controlada extruida por fusion en caliente.
WO2011009603A1 (fr) 2009-07-22 2011-01-27 Grünenthal GmbH Forme galénique inviolable pour des opioïdes sensibles à l’oxydation
KR20130097202A (ko) 2010-09-02 2013-09-02 그뤼넨탈 게엠베하 무기 염을 포함하는 내변조성 투여형
AR082862A1 (es) 2010-09-02 2013-01-16 Gruenenthal Gmbh Forma de dosificacion resistente a alteracion que comprende un polimero anionico
AU2012292418B2 (en) 2011-07-29 2017-02-16 Grunenthal Gmbh Tamper-resistant tablet providing immediate drug release
EA201400172A1 (ru) 2011-07-29 2014-06-30 Грюненталь Гмбх Устойчивая к разрушению таблетка, которая обеспечивает немедленное высвобождение лекарственного средства
AU2013225106B2 (en) 2012-02-28 2017-11-02 Grunenthal Gmbh Tamper-resistant dosage form comprising pharmacologically active compound and anionic polymer
EA201401139A1 (ru) 2012-04-18 2015-03-31 Грюненталь Гмбх Устойчивая к разрушению и к сбросу дозы фармацевтическая лекарственная форма
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
WO2014191396A1 (fr) 2013-05-29 2014-12-04 Grünenthal GmbH Forme dosifiée inviolable à profil de libération bimodale
CA2907950A1 (fr) 2013-05-29 2014-12-04 Grunenthal Gmbh Forme pharmaceutique inviolable contenant une ou plusieurs particules
WO2015004245A1 (fr) 2013-07-12 2015-01-15 Grünenthal GmbH Forme posologique inviolable contenant un polymère d'éthylène-acétate de vinyle
MX371372B (es) 2013-11-26 2020-01-28 Gruenenthal Gmbh Preparacion de una composicion farmaceutica en polvo por medio de criomolienda.
AU2015261060A1 (en) 2014-05-12 2016-11-03 Grunenthal Gmbh Tamper resistant immediate release capsule formulation comprising Tapentadol
EA201692388A1 (ru) 2014-05-26 2017-05-31 Грюненталь Гмбх Лекарственная форма в виде множества частиц, защищенная от вызываемого этанолом сброса дозы
WO2016170097A1 (fr) 2015-04-24 2016-10-27 Grünenthal GmbH Forme galénique inviolable avec libération immédiate et résistance à l'extraction par solvant.
AU2016319203A1 (en) 2015-09-10 2018-02-22 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
EP3252055B1 (fr) 2016-05-31 2018-09-19 Alcaliber Investigacion Desarrollo e Innovacion SLU Procédé d'obtention de 3,14-diacetyloxymorphone à partir d'oripavine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3249616A (en) * 1966-05-03 Ix-dfflydroxy-g-oxo-n-phenethylmor- phinan (cis) and production thereof
US2806033A (en) * 1955-08-03 1957-09-10 Lewenstein Morphine derivative
US3775414A (en) * 1972-05-10 1973-11-27 Bristol Myers Co Process for the preparation of 14-hydroxymorphinan derivatives

Also Published As

Publication number Publication date
IL58489A0 (en) 1980-01-31
NL7920126A (nl) 1980-08-29
CS211364B2 (en) 1982-02-26
AU5189779A (en) 1980-04-24
CA1108132A (fr) 1981-09-01
JPS55501025A (fr) 1980-11-27
SE8004454L (sv) 1980-06-16
FI793235A (fi) 1980-04-20
ES485154A1 (es) 1980-06-16
GB2049680A (en) 1980-12-31
FR2439201A1 (fr) 1980-05-16
NO793297L (no) 1980-04-22
WO1980000841A1 (fr) 1980-05-01
IT7969032A0 (it) 1979-10-18
DK258280A (da) 1980-06-17

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