BE872990A - Trans-4a-aryl-octahydro-1h-2-pyrindines et leur utilisation therapeutique - Google Patents
Trans-4a-aryl-octahydro-1h-2-pyrindines et leur utilisation therapeutiqueInfo
- Publication number
- BE872990A BE872990A BE1009211A BE1009211A BE872990A BE 872990 A BE872990 A BE 872990A BE 1009211 A BE1009211 A BE 1009211A BE 1009211 A BE1009211 A BE 1009211A BE 872990 A BE872990 A BE 872990A
- Authority
- BE
- Belgium
- Prior art keywords
- pyrindins
- octahydro
- trans
- aryl
- therapeutic use
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86489977A | 1977-12-27 | 1977-12-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE872990A true BE872990A (fr) | 1979-06-22 |
Family
ID=25344312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE1009211A BE872990A (fr) | 1977-12-27 | 1978-12-22 | Trans-4a-aryl-octahydro-1h-2-pyrindines et leur utilisation therapeutique |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP0002937A1 (fr) |
| JP (1) | JPS5498770A (fr) |
| AR (1) | AR221352A1 (fr) |
| AU (1) | AU4286678A (fr) |
| BE (1) | BE872990A (fr) |
| BG (1) | BG30927A3 (fr) |
| CA (1) | CA1105026A (fr) |
| CS (1) | CS203940B2 (fr) |
| DD (1) | DD141156A5 (fr) |
| DK (1) | DK577078A (fr) |
| ES (1) | ES476385A1 (fr) |
| FI (1) | FI783992A (fr) |
| FR (1) | FR2413370A1 (fr) |
| GB (1) | GB2010806A (fr) |
| GR (1) | GR70349B (fr) |
| IL (1) | IL56268A0 (fr) |
| IT (1) | IT1101682B (fr) |
| LU (1) | LU80719A1 (fr) |
| NZ (1) | NZ189230A (fr) |
| PL (1) | PL117572B1 (fr) |
| PT (1) | PT68934A (fr) |
| RO (1) | RO75805A (fr) |
| SU (1) | SU841586A3 (fr) |
| ZA (1) | ZA787156B (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4579952A (en) * | 1981-12-28 | 1986-04-01 | E. I. Du Pont De Nemours And Company | Intermediates for octahydrobenzofuro[3,2-e]isoquinolines |
| US4415736A (en) * | 1981-12-28 | 1983-11-15 | E. I. Du Pont De Nemours & Co. | Certain tetrahydropyridine intermediates |
| US4537963A (en) * | 1981-12-28 | 1985-08-27 | E. I. Du Pont De Nemours And Company | Intermediates for octahydrobenzofuro[3,2-E]isoquinolines |
| FR2617481B1 (fr) * | 1987-07-03 | 1989-11-10 | Roussel Uclaf | Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
| HUE028983T2 (en) | 2010-05-06 | 2017-01-30 | Vertex Pharma | Heterocyclic chromene-spirocyclic piperidine amides as ion channel modulators |
| KR101923367B1 (ko) | 2011-02-02 | 2018-12-04 | 버텍스 파마슈티칼스 인코포레이티드 | 이온 채널의 조절제로서의 피롤로피라진―스피로사이클릭 피페리딘 아미드 |
| AU2012217616B2 (en) | 2011-02-18 | 2017-03-02 | Vertex Pharmaceuticals Incorporated | Chroman - spirocyclic piperidine amides as modulators of ion channels |
| CN103517910B (zh) | 2011-03-14 | 2016-12-14 | 沃泰克斯药物股份有限公司 | 作为离子通道调节剂的吗啉-螺环哌啶酰胺 |
| CA2917198C (fr) * | 2013-07-10 | 2022-06-07 | Vertex Pharmaceuticals Incorporated | Amides de piperidine fusionnes utiles en tant que modulateurs de canaux ioniques |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA734895B (en) * | 1972-07-20 | 1974-06-26 | Du Pont | Analgesigs and/or narcotic antagonists |
| DE2336559A1 (de) * | 1972-07-20 | 1974-01-31 | Du Pont | 4a-aryl-trans-decahydrochinoline und verfahren zu ihrer herstellung |
| PT67194B (en) * | 1976-11-02 | 1979-03-23 | Lilly Co Eli | Process for preparing 4a-aryl-octahydro-1h-2-pyrindines |
-
1978
- 1978-12-19 BG BG041785A patent/BG30927A3/xx unknown
- 1978-12-19 PT PT68934A patent/PT68934A/pt unknown
- 1978-12-19 PL PL1978211919A patent/PL117572B1/pl unknown
- 1978-12-19 NZ NZ189230A patent/NZ189230A/xx unknown
- 1978-12-20 RO RO7895989A patent/RO75805A/fr unknown
- 1978-12-20 GR GR57949A patent/GR70349B/el unknown
- 1978-12-20 CA CA318,284A patent/CA1105026A/fr not_active Expired
- 1978-12-20 ZA ZA787156A patent/ZA787156B/xx unknown
- 1978-12-20 AR AR274886A patent/AR221352A1/es active
- 1978-12-21 GB GB7849437A patent/GB2010806A/en not_active Withdrawn
- 1978-12-21 FR FR7835977A patent/FR2413370A1/fr not_active Withdrawn
- 1978-12-21 EP EP78300879A patent/EP0002937A1/fr not_active Withdrawn
- 1978-12-21 IL IL56268A patent/IL56268A0/xx unknown
- 1978-12-22 LU LU80719A patent/LU80719A1/fr unknown
- 1978-12-22 AU AU42866/78A patent/AU4286678A/en active Pending
- 1978-12-22 BE BE1009211A patent/BE872990A/fr unknown
- 1978-12-22 IT IT31268/78A patent/IT1101682B/it active
- 1978-12-22 DK DK577078A patent/DK577078A/da not_active Application Discontinuation
- 1978-12-22 CS CS788854A patent/CS203940B2/cs unknown
- 1978-12-25 JP JP16448778A patent/JPS5498770A/ja active Pending
- 1978-12-26 SU SU782701053A patent/SU841586A3/ru active
- 1978-12-27 DD DD78210204A patent/DD141156A5/de unknown
- 1978-12-27 ES ES476385A patent/ES476385A1/es not_active Expired
- 1978-12-27 FI FI783992A patent/FI783992A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0002937A1 (fr) | 1979-07-11 |
| PT68934A (en) | 1979-01-01 |
| IT1101682B (it) | 1985-10-07 |
| BG30927A3 (en) | 1981-09-15 |
| AR221352A1 (es) | 1981-01-30 |
| NZ189230A (en) | 1981-05-15 |
| AU4286678A (en) | 1979-07-05 |
| CS203940B2 (en) | 1981-03-31 |
| LU80719A1 (fr) | 1979-04-13 |
| SU841586A3 (ru) | 1981-06-23 |
| FI783992A (fi) | 1979-06-28 |
| GB2010806A (en) | 1979-07-04 |
| JPS5498770A (en) | 1979-08-03 |
| PL117572B1 (en) | 1981-08-31 |
| DK577078A (da) | 1979-06-28 |
| ZA787156B (en) | 1980-08-27 |
| FR2413370A1 (fr) | 1979-07-27 |
| IT7831268A0 (it) | 1978-12-22 |
| GR70349B (fr) | 1982-09-23 |
| ES476385A1 (es) | 1979-11-16 |
| RO75805A (fr) | 1981-02-28 |
| IL56268A0 (en) | 1979-03-12 |
| CA1105026A (fr) | 1981-07-14 |
| DD141156A5 (de) | 1980-04-16 |
| PL211919A1 (pl) | 1979-09-10 |
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