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BE863429A - Derives de l'acide quinoleine-carboxylique - Google Patents

Derives de l'acide quinoleine-carboxylique

Info

Publication number
BE863429A
BE863429A BE2056647A BE2056647A BE863429A BE 863429 A BE863429 A BE 863429A BE 2056647 A BE2056647 A BE 2056647A BE 2056647 A BE2056647 A BE 2056647A BE 863429 A BE863429 A BE 863429A
Authority
BE
Belgium
Prior art keywords
quinolein
carboxylic acid
acid derivatives
derivatives
carboxylic
Prior art date
Application number
BE2056647A
Other languages
English (en)
Original Assignee
Kyorin Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=13020985&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BE863429(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyorin Seiyaku Kk filed Critical Kyorin Seiyaku Kk
Publication of BE863429A publication Critical patent/BE863429A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
BE2056647A 1977-05-16 1978-01-30 Derives de l'acide quinoleine-carboxylique BE863429A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5621977A JPS53141286A (en) 1977-05-16 1977-05-16 Novel substituted quinolinecarboxylic acid

Publications (1)

Publication Number Publication Date
BE863429A true BE863429A (fr) 1978-05-16

Family

ID=13020985

Family Applications (1)

Application Number Title Priority Date Filing Date
BE2056647A BE863429A (fr) 1977-05-16 1978-01-30 Derives de l'acide quinoleine-carboxylique

Country Status (11)

Country Link
US (1) US4146719A (fr)
JP (1) JPS53141286A (fr)
AU (1) AU512940B2 (fr)
BE (1) BE863429A (fr)
CA (1) CA1178961A (fr)
DE (1) DE2804097C3 (fr)
FR (1) FR2391210A1 (fr)
GB (1) GB1574285A (fr)
HK (1) HK10385A (fr)
HU (1) HU176265B (fr)
SE (1) SE436129B (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000203A1 (fr) * 1977-07-01 1979-01-10 Ciba-Geigy Ag 1-Ethyl-7-chloro-6-fluoro-4-quinolone-3-acide carboxylique, sa préparation et son application comme bactéricide pour plantes
FR2403339A1 (fr) * 1977-09-20 1979-04-13 Bellon Labor Sa Roger Nouveaux acides dialkylamino-7 halogeno-6 oxo-4 dihydro-1,4 quinoleine-3 carboxyliques, procede pour leur preparation, et leur application comme medicament
EP0009425A1 (fr) * 1978-08-25 1980-04-02 Société anonyme dite: LABORATOIRE ROGER BELLON Dérivés de la naphtyridine et compositions pharmaceutiques les contenant
WO1986006630A1 (fr) * 1985-05-14 1986-11-20 Beecham Group P.L.C. Utilisation de derives de quinolone pour le traitement de la pneumonie mycoplasmatique chez les porcs
EP0142426A3 (fr) * 1983-11-14 1986-12-17 Merck & Co. Inc. Formulation ophtalmique contenant de la norfloxacine et antibiotiques apparentés
EP0210513A1 (fr) * 1985-07-24 1987-02-04 Bayer Ag Préparations pour le traîtement des mycoplasmoses et des infections bactériennes chez la volaille
WO1987003587A1 (fr) 1985-12-09 1987-06-18 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Procede pour la preparation d'acides carboxyliques de quinoleine
WO1987003595A1 (fr) 1985-12-09 1987-06-18 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Intermediaire de la norfloxacine

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292317A (en) * 1977-09-20 1981-09-29 Laboratorie Roger Bellon 1,4-Dihydro-quinoline-3-carboxylic acid derivatives, process for their preparation and compositions containing them
US4416884A (en) * 1978-04-12 1983-11-22 Otsuka Pharmaceutical Co., Ltd. Piperazinylbenzoheterocyclic compounds
JPS5533453A (en) * 1978-08-31 1980-03-08 Dainippon Pharmaceut Co Ltd Preventive and remedy for infectious disease of fish
JPS5845426B2 (ja) * 1978-09-29 1983-10-08 杏林製薬株式会社 置換キノリンカルボン酸誘導体
JPS55100364A (en) * 1979-01-26 1980-07-31 Dainippon Pharmaceut Co Ltd Pyridonecarboxylic acid derivative and its salt
JPS604820B2 (ja) * 1979-02-26 1985-02-06 大塚製薬株式会社 キノリンカルボン酸誘導体
JPS5630964A (en) * 1979-08-22 1981-03-28 Kyorin Pharmaceut Co Ltd Novel substituted quinolinecarboxylic acid and its preparation
DE3142854A1 (de) * 1981-10-29 1983-05-11 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7-piperazino-chinolin-3-carbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4670444B1 (en) * 1980-09-03 1999-02-09 Bayer Ag and-naphthyridine-3-carboxylic acids and antibacte7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-quinoline-rial agents containing these compounds
JPS5762259A (en) * 1980-09-05 1982-04-15 Kyorin Pharmaceut Co Ltd Preparation of substituted quinolinecarboxylic acid derivative
IE52125B1 (en) * 1980-10-02 1987-06-24 Fox Charles L Jun 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quino-line carboxylic acid and metal salts thereof useful in burn therapy
US4522819A (en) * 1980-10-02 1985-06-11 Norwich Eaton Pharmaceuticals, Inc. 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid and metal salts thereof useful in burn therapy
JPS57106681A (en) * 1980-12-24 1982-07-02 Dainippon Pharmaceut Co Ltd 1,8-naphthyridine derivative and its salt
JPS57134482A (en) * 1981-02-13 1982-08-19 Dainippon Pharmaceut Co Ltd 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8- naphthyridine-3-carboxylic acid-3/2 hydrate and its preparation
SE440354B (sv) * 1981-02-19 1985-07-29 Kyorin Seiyaku Kk Kinolinkarboxylsyraderivat
JPS57145862A (en) * 1981-03-06 1982-09-09 Kyorin Pharmaceut Co Ltd Quinolinecarboxylic acid derivative
JPS57164216A (en) * 1981-04-03 1982-10-08 Babcock Hitachi Kk Removing method for ash by hopper
US4404197A (en) * 1981-05-15 1983-09-13 Fox Jr Charles L Antimicrobial compositions containing 1-ethyl-6-fluoro-1,4-dihydro-4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid or metal salts thereof and silver sulfadiazine
JPS57203067A (en) * 1981-06-10 1982-12-13 Kanebo Ltd Novel quinolinecarboxylic acid derivatives, their preparations, and antibacterial agent comprising them as active ingredient
US4499091A (en) * 1982-03-31 1985-02-12 Sterling Drug Inc. 1-Amino (or substituted amino)-1,4-dihydro-4-oxo-6-fluoro-7-heterylquinoline-3-carboxylic acids and their use as antibacterial agents
DE3363711D1 (en) * 1982-03-31 1986-07-03 Sterling Drug Inc New quinolone compounds and preparation thereof
ZA832057B (en) * 1982-03-31 1984-06-27 Sterling Drug Inc New quinolone compounds and preparation thereof
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
JPS59122470A (ja) * 1982-12-27 1984-07-14 Dai Ichi Seiyaku Co Ltd キノリン−３−カルボン酸誘導体の製造法
DE3248507A1 (de) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen Mikrobizide mittel auf chinoloncarbonsaeure basis
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
EP0154622A4 (fr) * 1983-09-12 1987-03-16 Research Corp Compositions antimicrobiennes contenant de l'acide carboxylique de 1-ethyl-6-fluoro-1,4-dihydro-oxo-7-(1-piperazinyl)-3-quinoline ou ses sels metalliques et de la sulfadiazine d'argent.
AU553415B2 (en) * 1983-09-19 1986-07-17 Abbott Japan Co., Ltd. 6-fluoro-1-4-dihydro-4-oxo-7-substituted piperazinyl- quinoline-3-carboxylic acids
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
US4698350A (en) * 1984-09-17 1987-10-06 Sterling Drug Inc. 1-ethyl-6-fluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarboxylic acid and antibacterial use thereof
EP0181521A1 (fr) * 1984-10-19 1986-05-21 Otsuka Pharmaceutical Co., Ltd. Composés d'acide 1-phényl substitué-4-oxo-3-quinoléine carboxylique
US4851535A (en) * 1985-01-23 1989-07-25 Toyama Chemical Co., Ltd. Nicotinic acid derivatives
US4755513A (en) * 1985-01-30 1988-07-05 Otsuka Pharmaceutical Company, Limited Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds
HUT40429A (en) * 1985-04-29 1986-12-28 Chinoin Gyogyszer Es Vegyeszet Process for production of salts of derivatives of kynolin carbonic acid
US4684648A (en) * 1985-05-10 1987-08-04 Otsuka Pharmaceutical Company Limited Antimicrobial 1-substituted phenyl-4-oxoquinoline-3-carboxylic acid compounds and compositions thereof
IN166416B (fr) * 1985-09-18 1990-05-05 Pfizer
EP0224121A3 (fr) * 1985-11-19 1987-11-11 ROTTAPHARM S.p.A. Dérivés de 7-[4-aminopipérazinyl] ou 7-[4-chloropipérazinyl]quinoléinone, leur procédé de préparation et compositions pharmaceutiques les contenant
US4687770A (en) * 1985-12-23 1987-08-18 Abbott Laboratories Isoxazolo-pyrido-benzoxazine and isothiazolo-pyrido-benzoxazine derivatives
US4689325A (en) * 1985-12-23 1987-08-25 Abbott Laboratories Isoxazolo-pyrido-phenoxazine and isothiazolo-pyrido-phenoxazine derivatives
US4692454A (en) * 1986-02-03 1987-09-08 Warner-Lambert Company Opthalmic use of quinolone antibiotics
IL80459A (en) * 1986-10-30 1991-04-15 Abic Ltd Water-soluble adduct of norfloxacin and nicotinic acid
DE3641312A1 (de) * 1986-12-03 1988-06-09 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
WO1989005643A1 (fr) * 1987-12-18 1989-06-29 Pfizer Inc. Acides carboxyliques de quinoline a substitution heterocyclique
US4920120A (en) 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
US5585491A (en) * 1988-01-25 1996-12-17 Otsuka Pharmaceutical Co., Ltd. Antibacterial agents
KR910003630B1 (ko) * 1988-06-17 1991-06-07 한국과학기술원 벤조일 아세틱 에스테르 유도체 및 그 제조방법
US5491139A (en) * 1988-10-24 1996-02-13 The Procter & Gamble Company Antimicrobial quinolonyl lactams
US5328908A (en) * 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
CA2001203C (fr) * 1988-10-24 2001-02-13 Thomas P. Demuth, Jr. Dithiocarbamoyl quinolones antimicrobiens
US5180719A (en) * 1988-10-24 1993-01-19 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl lactam esters
US5273973A (en) * 1988-10-24 1993-12-28 Norwich Eaton Pharmaceuticals, Inc. Antimicrobial quinolonyl esters
EP0997466A1 (fr) * 1988-10-24 2000-05-03 PROCTER & GAMBLE PHARMACEUTICALS, INC. Lactam-quinolones antimicrobiennes
US5262417A (en) * 1988-12-06 1993-11-16 The Upjohn Company Antibacterial quinolone compounds
US5214051A (en) * 1989-08-01 1993-05-25 Pfizer Inc. Thiazolyl and oxazolyl[5,4-c]piperidyl-substituted quinolone-carboxylic acid and related analogs thereof having antibacterial properties are disclosed
ES2147721T3 (es) * 1990-04-18 2000-10-01 Procter & Gamble Pharma Quinolonil lactamas antimicrobianas.
WO1993005816A1 (fr) * 1991-09-17 1993-04-01 Alcon Laboratories, Inc. Compositions contenant des antibiotiques quinolone et du sulfonate de polystyrol
AU4272793A (en) * 1993-04-24 1994-11-21 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and process for preparing the same
ATE188377T1 (de) * 1993-06-29 2000-01-15 Takeda Chemical Industries Ltd Chinoline oder chinazolin-derivate und deren verwendung zur herstellung eines medikaments für die behandlung von osteoporose
AU679961B2 (en) * 1993-08-13 1997-07-17 Dong Wha Pharmaceutical Industrial Co., Ltd. Novel quinolone carboxylic acid derivatives
KR950018003A (ko) * 1993-12-09 1995-07-22 스미스클라인 비참 피엘씨 신규한 퀴놀론 유도체 및 그의 제조 방법
EP0787720B1 (fr) * 1994-10-20 2003-07-16 Wakunaga Seiyaku Kabushiki Kaisha Derive de pyridone-carboxylate, ou sel de celui-ci, et antibacterien le contenant comme principe actif
US5602254A (en) * 1995-05-26 1997-02-11 Warner-Lambert Company Method for making quinoline carboxylic acids or naphthyridine carboxylic acids in free base form
DK0897919T3 (da) 1996-04-19 2004-09-27 Wakunaga Pharma Co Ltd Nye pyridoncarboxylsyrederivater eller salte deraf samt antibakterielle midler indeholdende disse som den aktive bestanddel
DE69802692D1 (de) 1997-06-26 2002-01-10 Dong Wha Pharm Ind Co Ltd Derivate der chinoloncarbonsäure
CN1343128B (zh) 1999-03-17 2010-04-21 第一制药株式会社 药物组合物
EP1219618A4 (fr) 1999-09-02 2002-09-18 Wakunaga Pharma Co Ltd Derive d'acide quinolinecarboxylique ou son sel
EP1282603A2 (fr) * 2000-05-09 2003-02-12 Natco Pharma Limited Procede ameliore de preparation de derives de quinolone
FR2916446B1 (fr) 2007-05-24 2009-08-21 Biocodex Sa Nouveau procede de synthese de fluoroquinolones
MX2018015462A (es) 2016-06-15 2019-05-27 Wakunaga Pharma Co Ltd Derivado novedoso del acido piridonacarboxilico o su sal.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1451911A (en) 1972-08-14 1976-10-06 Dainippon Pharmaceutical Co 2-1-piperazino-5-oxopyrido-2,3,d-pyrimidine-6-carboxylic acids their preparation and pharmaceutical compositions thereof
US4017622A (en) * 1972-12-18 1977-04-12 Dainippon Pharmaceutical Co., Ltd. Piperazine derivatives
HU168497B (fr) * 1972-12-18 1976-05-28
JPS5750784B2 (fr) * 1974-02-12 1982-10-28

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0000203A1 (fr) * 1977-07-01 1979-01-10 Ciba-Geigy Ag 1-Ethyl-7-chloro-6-fluoro-4-quinolone-3-acide carboxylique, sa préparation et son application comme bactéricide pour plantes
FR2403339A1 (fr) * 1977-09-20 1979-04-13 Bellon Labor Sa Roger Nouveaux acides dialkylamino-7 halogeno-6 oxo-4 dihydro-1,4 quinoleine-3 carboxyliques, procede pour leur preparation, et leur application comme medicament
FR2498931A1 (fr) * 1977-09-20 1982-08-06 Bellon Labor Sa Roger Medicament constitue par l'acide ethyl-1 fluoro-6 piperazinyl-7 oxo-4 dihydro-1,4 quinoleine-3 carboxylique et ses sels d'addition d'acides non toxiques pharmaceutiquement acceptables
EP0009425A1 (fr) * 1978-08-25 1980-04-02 Société anonyme dite: LABORATOIRE ROGER BELLON Dérivés de la naphtyridine et compositions pharmaceutiques les contenant
EP0142426A3 (fr) * 1983-11-14 1986-12-17 Merck & Co. Inc. Formulation ophtalmique contenant de la norfloxacine et antibiotiques apparentés
WO1986006630A1 (fr) * 1985-05-14 1986-11-20 Beecham Group P.L.C. Utilisation de derives de quinolone pour le traitement de la pneumonie mycoplasmatique chez les porcs
EP0210513A1 (fr) * 1985-07-24 1987-02-04 Bayer Ag Préparations pour le traîtement des mycoplasmoses et des infections bactériennes chez la volaille
US5145853A (en) * 1985-07-24 1992-09-08 Bayer Aktiengesellschaft Bactericidal formulations for use in veterinary medicine
WO1987003587A1 (fr) 1985-12-09 1987-06-18 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Procede pour la preparation d'acides carboxyliques de quinoleine
WO1987003595A1 (fr) 1985-12-09 1987-06-18 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Intermediaire de la norfloxacine
EP0351889A1 (fr) 1985-12-09 1990-01-24 CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. Procédé pour la préparation d'un acide carboxylique de quinoléine

Also Published As

Publication number Publication date
JPS53141286A (en) 1978-12-08
CA1178961A (fr) 1984-12-04
FR2391210B1 (fr) 1981-08-21
FR2391210A1 (fr) 1978-12-15
AU512940B2 (en) 1980-11-06
SE7800970L (sv) 1978-11-17
JPS5534144B2 (fr) 1980-09-04
SE436129B (sv) 1984-11-12
DE2804097B2 (de) 1980-01-03
DE2804097A1 (de) 1978-11-23
AU3271378A (en) 1979-08-02
US4146719A (en) 1979-03-27
HU176265B (en) 1981-01-28
HK10385A (en) 1985-02-15
GB1574285A (en) 1980-09-03
DE2804097C3 (de) 1980-08-28

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Legal Events

Date Code Title Description
CCPA Application for a supplementary protection certificate

Free format text: 093C0157

CCPV Grant of a supplementary protection certificate

Free format text: 093C0157, EXPIRES 19980509

RE20 Patent expired

Owner name: KYORIN SEIYAKU K.K.

Effective date: 19980130