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BE834369A - Nouveaux sels de biguanides - Google Patents

Nouveaux sels de biguanides

Info

Publication number
BE834369A
BE834369A BE160823A BE160823A BE834369A BE 834369 A BE834369 A BE 834369A BE 160823 A BE160823 A BE 160823A BE 160823 A BE160823 A BE 160823A BE 834369 A BE834369 A BE 834369A
Authority
BE
Belgium
Prior art keywords
biguanide salts
new
new biguanide
salts
biguanide
Prior art date
Application number
BE160823A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE834369A publication Critical patent/BE834369A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24Y being a hetero atom
    • C07C279/26X and Y being nitrogen atoms, i.e. biguanides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE160823A 1974-10-11 1975-10-10 Nouveaux sels de biguanides BE834369A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1369774A CH602612A5 (pt) 1974-10-11 1974-10-11

Publications (1)

Publication Number Publication Date
BE834369A true BE834369A (fr) 1976-04-12

Family

ID=4394567

Family Applications (1)

Application Number Title Priority Date Filing Date
BE160823A BE834369A (fr) 1974-10-11 1975-10-10 Nouveaux sels de biguanides

Country Status (26)

Country Link
US (1) US4028402A (pt)
JP (1) JPS51125718A (pt)
AR (1) AR209457A1 (pt)
AT (1) AT343676B (pt)
BE (1) BE834369A (pt)
BR (1) BR7506595A (pt)
CA (1) CA1053258A (pt)
CH (1) CH602612A5 (pt)
CU (1) CU34371A (pt)
DD (1) DD123322A5 (pt)
DE (1) DE2542598A1 (pt)
DK (1) DK140834B (pt)
ES (1) ES441673A1 (pt)
FI (1) FI752626A (pt)
FR (1) FR2287221A1 (pt)
GB (1) GB1473256A (pt)
IE (1) IE41807B1 (pt)
IL (1) IL48116A (pt)
LU (1) LU73557A1 (pt)
NL (1) NL7511890A (pt)
NO (1) NO753447L (pt)
PH (1) PH12279A (pt)
PL (1) PL95259B1 (pt)
SE (1) SE7511357L (pt)
SU (1) SU572200A3 (pt)
ZA (1) ZA755861B (pt)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2401898A1 (fr) * 1977-09-05 1979-03-30 Aec Chim Organ Biolog Nouveau sel de l'acide patoique
US20020006899A1 (en) * 1998-10-06 2002-01-17 Pospisilik Andrew J. Use of dipeptidyl peptidase IV effectors for lowering blood pressure in mammals
DE19616486C5 (de) 1996-04-25 2016-06-30 Royalty Pharma Collection Trust Verfahren zur Senkung des Blutglukosespiegels in Säugern
US6399658B1 (en) 1996-12-24 2002-06-04 Sumitomo Pharmaceuticals Co., Ltd. Composition containing ascorbic acid
DE19823831A1 (de) * 1998-05-28 1999-12-02 Probiodrug Ges Fuer Arzneim Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen
DE19828114A1 (de) 1998-06-24 2000-01-27 Probiodrug Ges Fuer Arzneim Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
DE19828113A1 (de) 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
DE19834591A1 (de) 1998-07-31 2000-02-03 Probiodrug Ges Fuer Arzneim Verfahren zur Steigerung des Blutglukosespiegels in Säugern
US20030176357A1 (en) * 1998-10-06 2003-09-18 Pospisilik Andrew J. Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels
DE19926233C1 (de) 1999-06-10 2000-10-19 Probiodrug Ges Fuer Arzneim Verfahren zur Herstellung von Thiazolidin
DE19940130A1 (de) * 1999-08-24 2001-03-01 Probiodrug Ges Fuer Arzneim Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung
CN1287779C (zh) * 1999-10-06 2006-12-06 黑川清 羰基压迫降低剂
US20080076811A1 (en) * 2000-01-21 2008-03-27 Bork Balkan Combinations comprising depeptidypeptidase-iv inhibitors and antidiabetic agents
CN101690815A (zh) * 2000-03-31 2010-04-07 普罗西迪恩有限公司 二肽基肽酶iv酶活性抑制剂的新用途
FR2809310B1 (fr) 2000-05-26 2004-02-13 Centre Nat Rech Scient Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant
JP2005097117A (ja) * 2000-06-30 2005-04-14 Chugai Pharmaceut Co Ltd 糖尿病治療剤
US7132104B1 (en) 2000-10-27 2006-11-07 Probiodrug Ag Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders
RU2286149C2 (ru) * 2000-10-27 2006-10-27 Пробиодруг Аг Способ для лечения неврологических и нейропсихологических нарушений
US6890905B2 (en) 2001-04-02 2005-05-10 Prosidion Limited Methods for improving islet signaling in diabetes mellitus and for its prevention
DE10150203A1 (de) 2001-10-12 2003-04-17 Probiodrug Ag Peptidylketone als Inhibitoren der DPIV
US20030130199A1 (en) * 2001-06-27 2003-07-10 Von Hoersten Stephan Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
US7368421B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
JP2005504766A (ja) * 2001-08-16 2005-02-17 プロバイオドラッグ アーゲー プロリンエンドペプチダーゼ阻害剤の、細胞内シグナルカスケード依存性イノシトール(1,4,5)トリホスフェート濃度調節への使用。
US6844316B2 (en) 2001-09-06 2005-01-18 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
ATE349435T1 (de) 2002-02-28 2007-01-15 Prosidion Ltd Dpiv-inhibitoren auf glutaminbasis
US20030232761A1 (en) * 2002-03-28 2003-12-18 Hinke Simon A. Novel analogues of glucose-dependent insulinotropic polypeptide
US20040033051A1 (en) * 2002-08-16 2004-02-19 Ip Kiril Kun Wan Method and system for producing and displaying visual presentations which inhibit off-screen duplication
DE60331747D1 (de) * 2002-09-18 2010-04-29 Prosidion Ltd Sekundäre bindungsstelle von dipeptidylpeptidase iv (dp iv)
US20040058876A1 (en) * 2002-09-18 2004-03-25 Torsten Hoffmann Secondary binding site of dipeptidyl peptidase IV (DP IV)
ATE462432T1 (de) 2003-05-05 2010-04-15 Probiodrug Ag Glutaminylcyclase-hemmer
EP1961416B1 (en) 2003-05-05 2013-01-23 Probiodrug AG Use of inhibitors of glutaminyl cyclase for treating psoriasis, rheumatoid arthritis or atherosclerosis.
DK1675578T3 (da) * 2003-10-15 2013-08-26 Probiodrug Ag Inhibitorer af glutaminyl- og glutamatcyclaser til behandling af de neurodegenerative sygdomme FBD og FDD
US20050171112A1 (en) * 2003-11-03 2005-08-04 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
US20100099721A1 (en) * 2003-11-03 2010-04-22 Probiodrug Ag Novel compounds for the treatment of neurological disorders
KR101099206B1 (ko) 2004-02-05 2011-12-27 프로비오드룩 아게 신규한 글루타미닐 시클라제 저해제
JP4592818B2 (ja) * 2007-01-29 2010-12-08 ハナル バイオファーマ カンパニー リミテッド N,n−ジメチルイミドジカルボンイミド酸ジアミドの酢酸塩、その製造方法、及びそれを含む薬剤学的組成物
WO2008097861A2 (en) * 2007-02-02 2008-08-14 Braincells, Inc. MODULATION OF NEUROGENESIS WITH BIGUANIDES AND GSK3-ß AGENTS
WO2009038396A2 (en) * 2007-09-21 2009-03-26 Hanall Pharmaceutical Company. Ltd N,n-dimethyl imidodicarbonimidic diamide dicarboxylate, method for producing the same and pharmaceutical compositions comprising the same
WO2009088220A2 (ko) * 2008-01-08 2009-07-16 Hanall Pharmaceutical Company. Ltd N,n-디메틸 이미도디카르본이미딕 디아미드의 니코틴산염, 그의 제조방법 및 그를 포함하는 약제학적 조성물
AU2008357111B2 (en) * 2008-06-26 2013-05-09 Laboratorios Silanes, S.A. De C.V. A new metformin Glycinate salt for blood glucose control
WO2010146604A2 (en) 2009-06-18 2010-12-23 Exemed Pharmaceuticals Processes for preparing metformin hydrochloride
WO2011049400A2 (ko) * 2009-10-23 2011-04-28 한올바이오파마주식회사 N,n-디메틸 이미도디카르본이미딕 디아미드의 산 부가염을 포함하는 항암용 약제학적 조성물
KR101324283B1 (ko) 2010-04-27 2013-11-01 한올바이오파마주식회사 바이구아나이드 화합물의 신규 염, 그의 제조방법, 그를 포함하는 약제학적 조성물
MX2019003725A (es) 2016-09-30 2019-08-12 Laboratorios Silanes S A De C V Glicinato de metformina, composiciones farmaceuticas que comprenden la misma, y metodos de uso de la misma.
WO2018060962A2 (en) 2016-09-30 2018-04-05 Laboratorios Silanes S.A. De C.V. Metformin amino acid compounds and methods of using the same
CN107118130A (zh) * 2017-05-11 2017-09-01 杜剑平 一类治疗肿瘤的药物化合物及其应用
CN106986791A (zh) * 2017-05-11 2017-07-28 杜剑平 一种治疗肿瘤的药物化合物及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3179562A (en) * 1961-08-23 1965-04-20 Du Pont Treatment of diabetes with alpha, alpha substituted acetic acid derivatives

Also Published As

Publication number Publication date
IE41807L (en) 1976-04-11
DD123322A5 (pt) 1976-12-12
BR7506595A (pt) 1976-08-17
DE2542598A1 (de) 1976-04-22
DK140834B (da) 1979-11-26
ES441673A1 (es) 1977-04-01
ATA776375A (de) 1977-10-15
NO753447L (pt) 1976-04-13
ZA755861B (en) 1976-08-25
US4028402A (en) 1977-06-07
PL95259B1 (pl) 1977-10-31
JPS51125718A (en) 1976-11-02
DK457475A (pt) 1976-04-12
PH12279A (en) 1978-12-12
CH602612A5 (pt) 1978-07-31
IL48116A0 (en) 1975-11-25
AR209457A1 (es) 1977-04-29
LU73557A1 (pt) 1977-05-24
IE41807B1 (en) 1980-03-26
NL7511890A (nl) 1976-04-13
FR2287221A1 (fr) 1976-05-07
AU8497775A (en) 1977-03-24
SE7511357L (sv) 1976-04-12
AT343676B (de) 1978-06-12
DK140834C (pt) 1980-04-28
IL48116A (en) 1979-07-25
GB1473256A (en) 1977-05-11
CU34371A (es) 1979-06-01
FI752626A (pt) 1976-04-12
SU572200A3 (ru) 1977-09-05
CA1053258A (en) 1979-04-24

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