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BE794377A - Nouveaux derives du benzo-cyclohepta-thiophene - Google Patents

Nouveaux derives du benzo-cyclohepta-thiophene

Info

Publication number
BE794377A
BE794377A BE794377DA BE794377A BE 794377 A BE794377 A BE 794377A BE 794377D A BE794377D A BE 794377DA BE 794377 A BE794377 A BE 794377A
Authority
BE
Belgium
Prior art keywords
cyclohepta
thiophene
benzo
new derivatives
derivatives
Prior art date
Application number
Other languages
English (en)
French (fr)
Inventor
J P Bourquin
G Schwarb
E Waldvogel
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Priority claimed from CH98872A external-priority patent/CH565172A5/de
Priority claimed from CH99072A external-priority patent/CH569006A5/de
Priority claimed from CH98672A external-priority patent/CH569012A5/de
Priority claimed from CH99272A external-priority patent/CH562244A5/de
Publication of BE794377A publication Critical patent/BE794377A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/08Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BE794377D 1972-01-24 Nouveaux derives du benzo-cyclohepta-thiophene BE794377A (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH98872A CH565172A5 (en) 1972-01-24 1972-01-24 4-piperidylidene benzocycloheptathiophenes - - antihistamines and serotonin and acetyl choline inhibitors
CH99072A CH569006A5 (en) 1972-01-24 1972-01-24 4-piperidylidene benzocycloheptathiophenes - - antihistamines and serotonin and acetyl choline inhibitors
CH98672A CH569012A5 (en) 1972-01-24 1972-01-24 4-piperidylidene benzocycloheptathiophenes - - antihistamines and serotonin and acetyl choline inhibitors
CH99272A CH562244A5 (en) 1972-01-24 1972-01-24 4-piperidylidene benzocycloheptathiophenes - - antihistamines and serotonin and acetyl choline inhibitors

Publications (1)

Publication Number Publication Date
BE794377A true BE794377A (fr) 1973-07-23

Family

ID=27428052

Family Applications (1)

Application Number Title Priority Date Filing Date
BE794377D BE794377A (fr) 1972-01-24 Nouveaux derives du benzo-cyclohepta-thiophene

Country Status (14)

Country Link
US (1) US3862156A (de)
JP (1) JPS5760351B2 (de)
BE (1) BE794377A (de)
CY (1) CY992A (de)
DD (1) DD102701A5 (de)
DE (1) DE2302944C2 (de)
FI (1) FI55843C (de)
FR (1) FR2183663B2 (de)
GB (1) GB1415591A (de)
HK (1) HK11279A (de)
HU (1) HU165130B (de)
MY (1) MY7900114A (de)
NL (1) NL7300796A (de)
SE (1) SE383347B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI761607A (de) * 1975-06-16 1976-12-17 Sandoz Ag
GB1570500A (en) * 1976-01-02 1980-07-02 Sandoz Ltd Anti-9,10-dihydro-4-(1-methyl-4-piperidylidene)-4h-benzo(4,5) cyclohepta (1,2-b)thiophen-10(9h)-one oxime
US4132796A (en) * 1977-12-01 1979-01-02 Merck & Co., Inc. Antipsychotic 3-trifluoromethylsulfinyl analogs of cyproheptadine
US4356184A (en) * 1980-06-04 1982-10-26 G. D. Searle & Co. Anti-allergic or antihypertensive 1-piperidinylmethyl benzenamines
US4355036A (en) * 1980-06-19 1982-10-19 Schering Corporation Tricyclic-substituted piperidine antihistamines
BR0013935A (pt) * 1999-09-13 2002-05-14 Bridge Pharma Inc IsÈmeros oticamente ativos de cetotifeno e metabólitos terapeuticamente ativos dos mesmos
JP5096500B2 (ja) 2008-01-30 2012-12-12 日本臓器製薬株式会社 ピペリジン誘導体
CN103619839B (zh) * 2011-06-28 2016-06-01 福建省闽东力捷迅药业有限公司 抗-变态反应的苯并环庚并噻吩衍生物
CN104045633B (zh) * 2014-06-26 2017-07-21 福建省闽东力捷迅药业有限公司 一种富马酸卢帕替芬晶型a及其制备方法
CN104031035B (zh) * 2014-06-26 2017-08-25 福建省闽东力捷迅药业有限公司 一种富马酸卢帕替芬混晶及其制备方法
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL130095C (de) * 1962-08-31
US3491103A (en) * 1963-12-19 1970-01-20 Sandoz Ag Certain 4h-benzo(4,5)cyclohepta-(1,2-b) thiophenes
US3466291A (en) * 1966-02-16 1969-09-09 Sandoz Ag 4(2-dialkylaminoethoxy or 2-piperidinoethoxy) - 9,10 - dihydro benzo(4,5)cyclohepta(1,2-b)thiophene derivatives
CH504466A (de) * 1969-02-07 1971-03-15 Sandoz Ag Verfahren zur Herstellung von 4-(1-Methyl-4-piperidyliden-N-oxid)- -9,10-dihydro-4H-benzo(4,5)cycloheptal(1,2-b)thiophen
CH531000A (de) * 1970-03-11 1972-11-30 Sandoz Ag Verfahren zur Herstellung neuer Benzocycloheptathiophene

Also Published As

Publication number Publication date
FR2183663A2 (de) 1973-12-21
CY992A (en) 1979-08-02
FI55843B (fi) 1979-06-29
DE2302944A1 (de) 1973-08-02
JPS5760351B2 (de) 1982-12-18
MY7900114A (en) 1979-12-31
JPS4885575A (de) 1973-11-13
DE2302944C2 (de) 1982-11-25
NL7300796A (de) 1973-07-26
US3862156A (en) 1975-01-21
HU165130B (de) 1974-06-28
GB1415591A (en) 1975-11-26
SE383347B (sv) 1976-03-08
FR2183663B2 (de) 1976-07-02
DD102701A5 (de) 1973-12-20
FI55843C (fi) 1979-10-10
HK11279A (en) 1979-03-16

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SANDOZ S.A.

Effective date: 19840122