[go: up one dir, main page]

BE783026A - Cytidines et leur procede de preparation - Google Patents

Cytidines et leur procede de preparation

Info

Publication number
BE783026A
BE783026A BE783026A BE783026A BE783026A BE 783026 A BE783026 A BE 783026A BE 783026 A BE783026 A BE 783026A BE 783026 A BE783026 A BE 783026A BE 783026 A BE783026 A BE 783026A
Authority
BE
Belgium
Prior art keywords
cytidines
preparation process
preparation
Prior art date
Application number
BE783026A
Other languages
English (en)
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of BE783026A publication Critical patent/BE783026A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
BE783026A 1971-05-04 1972-05-04 Cytidines et leur procede de preparation BE783026A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2122991A DE2122991C2 (de) 1971-05-04 1971-05-04 Verfahren zur Herstellung von Cytosin- und 6-Azacytosinnucleosiden

Publications (1)

Publication Number Publication Date
BE783026A true BE783026A (fr) 1972-11-06

Family

ID=5807376

Family Applications (1)

Application Number Title Priority Date Filing Date
BE783026A BE783026A (fr) 1971-05-04 1972-05-04 Cytidines et leur procede de preparation

Country Status (8)

Country Link
US (1) US3891623A (fr)
BE (1) BE783026A (fr)
CH (1) CH579585A5 (fr)
CS (1) CS171723B2 (fr)
DE (1) DE2122991C2 (fr)
FR (1) FR2135249B1 (fr)
GB (1) GB1395764A (fr)
NL (1) NL7206058A (fr)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4090021A (en) * 1971-10-08 1978-05-16 Schering Aktiengesellschaft Process for the production of N6 -substituted adenosine nucleotides and products resulting therefrom
DE2508312A1 (de) * 1975-02-24 1976-09-02 Schering Ag Neues verfahren zur herstellung von nucleosiden
DE2514275A1 (de) * 1975-03-27 1976-10-14 Schering Ag Verfahren zur herstellung von n- (polysaccharidyl)-stickstoffheterocyclen, insbesondere von pyrimidin- oder purinbasen
US4118484A (en) * 1976-03-29 1978-10-03 The Upjohn Company Method of treating rheumatoid arthritis
DE2621645C3 (de) * 1976-05-13 1981-08-06 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur Herstellung von Aminoderivaten von N-Heterocyclen
GB1601020A (en) 1978-04-24 1981-10-21 Stichting Grega Vzw 2'-deoxy-5 (2-halogenovinyl)-uridines
US4267171A (en) * 1979-07-02 1981-05-12 The Regents Of The University Of California C-5 Substituted cytosine nucleosides
US4754026A (en) * 1985-06-04 1988-06-28 Takeda Chemical Industries, Ltd. Conversion of uracil derivatives to cytosine derivatives
FR2590255B1 (fr) * 1985-11-19 1987-12-24 Rhone Poulenc Sante Procede de preparation de derives de la pteridine
US4788181A (en) * 1986-09-29 1988-11-29 The United States Of America As Represented By The Department Of Health And Human Services 5-substituted-2',3'-dideoxycytidine compounds with anti-HTLV-III activity
US6432924B1 (en) 1993-12-26 2002-08-13 East Carolina University Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase
US8236493B2 (en) * 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US6974666B1 (en) * 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
WO1997023230A1 (fr) * 1995-12-22 1997-07-03 East Carolina University Procede de traitement des troubles caracterises par une surexpression de la cytidine-desaminase ou de la desoxycytidine-desaminase
US6864059B2 (en) * 1996-01-23 2005-03-08 Affymetrix, Inc. Biotin containing C-glycoside nucleic acid labeling compounds
EP0880598A4 (fr) * 1996-01-23 2005-02-23 Affymetrix Inc Evaluation rapide de difference d'abondance d'acides nucleiques, avec un systeme d'oligonucleotides haute densite
US7423143B2 (en) * 1996-01-23 2008-09-09 Affymetrix. Inc. Nucleic acid labeling compounds
US20010018514A1 (en) * 1998-07-31 2001-08-30 Mcgall Glenn H. Nucleic acid labeling compounds
US7282327B2 (en) * 1996-01-23 2007-10-16 Affymetrix, Inc. Nucleic acid labeling compounds
US6965020B2 (en) 1996-01-23 2005-11-15 Affymetrix, Inc. Nucleic acid labeling compounds
US7291463B2 (en) * 1996-01-23 2007-11-06 Affymetrix, Inc. Nucleic acid labeling compounds
US20040210045A1 (en) * 1996-01-23 2004-10-21 Mcgall Glenn Nucleic acid labeling compounds
MY164523A (en) * 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
KR20080021797A (ko) 2000-05-26 2008-03-07 이데닉스(케이만)리미티드 플라비바이러스 및 페스티바이러스의 치료방법 및 조성물
US20030008841A1 (en) * 2000-08-30 2003-01-09 Rene Devos Anti-HCV nucleoside derivatives
EP1385829A4 (fr) 2001-03-12 2005-10-19 Affymetrix Inc Composes de marquage d'acide nucleique
US7608600B2 (en) 2002-06-28 2009-10-27 Idenix Pharmaceuticals, Inc. Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
CN101172993A (zh) * 2002-06-28 2008-05-07 埃迪尼克斯(开曼)有限公司 用于治疗黄病毒感染的2′－c－甲基－3′－o－l－缬氨酸酯核糖呋喃基胞苷
US7662798B2 (en) * 2002-06-28 2010-02-16 Idenix Pharmaceuticals, Inc. 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
US7824851B2 (en) 2002-11-15 2010-11-02 Idenix Pharmaceuticals, Inc. 2′-branched nucleosides and Flaviviridae mutation
EP1585529A4 (fr) * 2002-12-12 2008-05-28 Idenix Cayman Ltd Procede de production de nucleosides ramifies en position 2'
US6943249B2 (en) * 2003-03-17 2005-09-13 Ash Stevens, Inc. Methods for isolating crystalline Form I of 5-azacytidine
US6887855B2 (en) * 2003-03-17 2005-05-03 Pharmion Corporation Forms of 5-azacytidine
US7038038B2 (en) * 2003-03-17 2006-05-02 Pharmion Corporation Synthesis of 5-azacytidine
WO2004084453A2 (fr) * 2003-03-20 2004-09-30 Microbiologica Quimica E Farmaceutica Ltd. Procedes de fabrication de 2'-desoxy-$g(b)-l-nucleosides
CN1812995A (zh) 2003-04-28 2006-08-02 艾登尼科斯（开曼）有限公司 工业化规模的核苷合成
MXPA06000162A (es) * 2003-06-30 2006-03-21 Idenix Cayman Ltd Sintesis de ?-l-2-desoxinucleosidos.
JP4516863B2 (ja) * 2005-03-11 2010-08-04 株式会社ケンウッド 音声合成装置、音声合成方法及びプログラム
US7781576B2 (en) 2005-12-23 2010-08-24 Idenix Pharmaceuticals, Inc. Process for preparing a synthetic intermediate for preparation of branched nucleosides
BRPI0817269A2 (pt) * 2007-09-26 2014-10-07 Sinai School Medicine Análogos de azacitidina e usos dos mesmos
ES2893785T3 (es) 2008-05-15 2022-02-10 Celgene Corp Formulaciones orales de análogos de citidina y métodos de uso de los mismos
CN103619864A (zh) 2011-03-31 2014-03-05 细胞基因国际有限公司 5-氮杂胞苷的合成

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1030970A (en) * 1964-05-15 1966-05-25 Inst Mikrobiologii Im Akad D K Method for the preparation of 2', 3', 5'-tri-o-acyl-6-azacytidines
US3328389A (en) * 1964-08-07 1967-06-27 Sankyo Co Process for preparing nucleotide derivatives
US3328388A (en) * 1964-09-02 1967-06-27 Merck & Co Inc Arabinofuranosyl pyrimidines and methods of preparing same
US3354160A (en) * 1965-07-22 1967-11-21 Hoffmann La Roche Tri-lower alkyl-silyl-5-fluoropyrimidines
US3346561A (en) * 1965-10-24 1967-10-10 Merck & Co Inc Pyrimidine 3-deoxynucleosides
US3404144A (en) * 1965-12-23 1968-10-01 Research Corp 1-beta-d-arabinofuranosyl-5-fluorocytosine compounds
DE1795357A1 (de) * 1968-09-18 1972-01-05 Schering Ag 2-Thio-pyrimidin-nucleoside
US3721664A (en) * 1970-01-27 1973-03-20 Hoffmann La Roche Preparation of 5-cytosine nucleosides

Also Published As

Publication number Publication date
FR2135249B1 (fr) 1975-10-17
NL7206058A (fr) 1972-11-07
US3891623A (en) 1975-06-24
CS171723B2 (fr) 1976-10-29
DE2122991A1 (de) 1972-11-16
FR2135249A1 (fr) 1972-12-15
GB1395764A (en) 1975-05-29
DE2122991C2 (de) 1982-06-09
CH579585A5 (fr) 1976-09-15

Similar Documents

Publication Publication Date Title
BE783026A (fr) Cytidines et leur procede de preparation
BE764179A (fr) " 5-azapyrimidine-nucleosides et leur procede de preparation
BE823973A (fr) Beta-aminoethylsilanes et leur procede de preparation
BE762038A (fr) Capsules minuscules et leur procede de preparation
BE820385A (fr) D-homo-steroides et leur procede de preparation
BE782847A (fr) Triazolobenzodiazepines et leur procede de
BE795705A (fr) Procede de preparation de polyfluoroalcools et leur application
BE793142A (fr) Nitroimidazoles, et leur procede de preparation
BE749413A (fr) Briques silico-calcaires et leur procede de preparation
BE792482A (fr) Nouveaux agents adhesifs et leur procede de preparation
BE788093A (fr) Phosphinylalcoylaminobenzophenones et leur procede de preparation
BE792724A (fr) Derives de pyrazinoindole et leur procede de preparation
BE776457A (fr) Coacervats thermoreversibles et procede de leur preparation
BE780993A (fr) Hemopeptides et leur procede de preparation
BE785998A (fr) Derives de thieno-diazepine et leur procede de preparation
BE779976A (fr) Nouveaux n-acyl-(piperazinoalcoyl)-pyrazoles et leur procede depreparation
BE753632A (fr) Nitrofuryl-aminoalkoxy-pyrimidines et leur procede de preparation
BE799339A (fr) Nouvelles 2-benzoyl-3-amino-pyridines et leur procede de preparation
BE790549A (fr) Derives de thiazoloquinoleine et leur procede de preparation
BE791638A (fr) Sulfonyl-urees, leur procede de preparation et leurs applications
BE754110A (fr) 14beta-hydroxy-15alpha-acyloxy-cardenolides et leur procede de preparation
BE755922A (fr) Polyisocyanurates-polyurees et leur procede de preparation
BE785366A (fr) Derives de 5-nitrothiazole et leur procede de
BE806909A (fr) 2-amino-2-oxazolines leur procede de preparation et leur applications
BE783400A (fr) Arylaminobutanols cardioactifs et leur procede de preparation