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BE746816A - Procede de preparation de pyrazinamides et nouveaux composes intermediaires de cette preparation - Google Patents

Procede de preparation de pyrazinamides et nouveaux composes intermediaires de cette preparation

Info

Publication number
BE746816A
BE746816A BE746816DA BE746816A BE 746816 A BE746816 A BE 746816A BE 746816D A BE746816D A BE 746816DA BE 746816 A BE746816 A BE 746816A
Authority
BE
Belgium
Prior art keywords
pyrazinamides
preparing
preparation
intermediate compounds
new intermediate
Prior art date
Application number
Other languages
English (en)
Inventor
K L Shepard
E J Cragoe Jr
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of BE746816A publication Critical patent/BE746816A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BE746816D 1969-03-05 1970-03-04 Procede de preparation de pyrazinamides et nouveaux composes intermediaires de cette preparation BE746816A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80466369A 1969-03-05 1969-03-05

Publications (1)

Publication Number Publication Date
BE746816A true BE746816A (fr) 1970-09-04

Family

ID=25189519

Family Applications (1)

Application Number Title Priority Date Filing Date
BE746816D BE746816A (fr) 1969-03-05 1970-03-04 Procede de preparation de pyrazinamides et nouveaux composes intermediaires de cette preparation

Country Status (4)

Country Link
US (1) US3573306A (fr)
BE (1) BE746816A (fr)
IL (1) IL33940A0 (fr)
NL (1) NL7001141A (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196292A (en) * 1977-06-29 1980-04-01 Merck & Co., Inc. 6-Substituted amiloride derivatives
IE52345B1 (en) * 1981-02-02 1987-09-16 Ici Plc Alkanolamine derivatives
US6858614B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenolic guanidine sodium channel blockers
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6903105B2 (en) * 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US7375107B2 (en) * 2003-08-18 2008-05-20 Parion Sciences, Inc. Alaphatic pyrazinoylguanidine sodium channel blockers
US7745442B2 (en) * 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
US20090253714A1 (en) * 2003-08-20 2009-10-08 Johnson Michael R Methods of reducing risk of infection from pathogens
CA2555402A1 (fr) * 2004-02-12 2005-09-01 Celine Bonnefous Amides bipyridyles en tant que modulateurs du recepteur-5 metabotropique du glutamate
EP1879871A1 (fr) * 2005-05-03 2008-01-23 Bayer CropScience S.A. Nouveaux derives d'heterocyclylethylamide
US20070021439A1 (en) * 2005-07-25 2007-01-25 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers
WO2009074575A2 (fr) * 2007-12-10 2009-06-18 Novartis Ag Composés organiques
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
WO2013038390A1 (fr) * 2011-09-16 2013-03-21 Novartis Ag Hétérocyclyle carboxamides n-substitués
WO2014099676A1 (fr) 2012-12-17 2014-06-26 Parion Sciences, Inc. Dérivés de chloro-pyrazine carboxamide utiles dans le traitement de maladies favorisées par une hydratation insuffisante des muqueuses
NZ709197A (en) 2012-12-17 2020-06-26 Parion Sciences Inc 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
UY36034A (es) 2014-03-18 2015-09-30 Astrazeneca Ab Derivados de 3,5-diamino-6-cloro-pirazina-2-carboxamida y sales farmaceuticamente aceptables de estos
AR126669A1 (es) * 2021-08-02 2023-11-01 Eurofarma Laboratorios S A COMPUESTOS N-ACILIDRAZÓNICOS INHIBIDORES DE Nav 1.7 Y/O Nav 1.8, SUS PROCESOS DE OBTENCIÓN, COMPOSICIONES, USOS, MÉTODOS DE TRATAMIENTO DE ESTOS Y KITS

Also Published As

Publication number Publication date
US3573306A (en) 1971-03-30
NL7001141A (fr) 1970-09-08
IL33940A0 (en) 1970-04-20

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