BE533269A - - Google Patents

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Publication number: BE533269A
Authority: BE; Belgium
Prior art keywords: sep; brown; mycelium; white; tetracycline
Prior art date: 1953-11-12

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1953-11-12

Publication of BE533269A publication Critical patent/BE533269A/fr

Links

230000003115 biocidal effect Effects 0.000 claims description 41
229930101283 tetracycline Natural products 0.000 claims description 39
239000004098 Tetracycline Substances 0.000 claims description 37
229960002180 tetracycline Drugs 0.000 claims description 37
235000019364 tetracycline Nutrition 0.000 claims description 37
150000003522 tetracyclines Chemical class 0.000 claims description 36
238000000855 fermentation Methods 0.000 claims description 35
230000004151 fermentation Effects 0.000 claims description 34
238000000034 method Methods 0.000 claims description 22
235000015097 nutrients Nutrition 0.000 claims description 13
241000187747 Streptomyces Species 0.000 claims description 12
244000005700 microbiome Species 0.000 claims description 10
238000004519 manufacturing process Methods 0.000 claims description 7
238000002360 preparation method Methods 0.000 claims description 7
235000013312 flour Nutrition 0.000 claims description 6
150000001720 carbohydrates Chemical class 0.000 claims description 2
125000001477 organic nitrogen group Chemical group 0.000 claims description 2
235000010633 broth Nutrition 0.000 description 25
229920001817 Agar Polymers 0.000 description 24
239000008272 agar Substances 0.000 description 24
239000000047 product Substances 0.000 description 21
240000007817 Olea europaea Species 0.000 description 20
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XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 15
229910052751 metal Inorganic materials 0.000 description 14
239000002184 metal Substances 0.000 description 14
244000223760 Cinnamomum zeylanicum Species 0.000 description 13
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 13
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PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 9
241000219100 Rhamnaceae Species 0.000 description 9
150000002739 metals Chemical class 0.000 description 9
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 8
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235000016639 Syzygium aromaticum Nutrition 0.000 description 3
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239000002585 base Substances 0.000 description 3
CYDMQBQPVICBEU-XRNKAMNCSA-N chlortetracycline Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-XRNKAMNCSA-N 0.000 description 3
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KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
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239000011701 zinc Substances 0.000 description 3
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FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
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VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
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239000005018 casein Substances 0.000 description 2
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235000020232 peanut Nutrition 0.000 description 1
230000000737 periodic effect Effects 0.000 description 1
WVDDGKGOMKODPV-ZQBYOMGUSA-N phenyl(114C)methanol Chemical compound O[14CH2]C1=CC=CC=C1 WVDDGKGOMKODPV-ZQBYOMGUSA-N 0.000 description 1
229940067107 phenylethyl alcohol Drugs 0.000 description 1
238000000053 physical method Methods 0.000 description 1
230000008635 plant growth Effects 0.000 description 1
239000002798 polar solvent Substances 0.000 description 1
229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
239000001205 polyphosphate Substances 0.000 description 1
235000011176 polyphosphates Nutrition 0.000 description 1
229910000160 potassium phosphate Inorganic materials 0.000 description 1
235000011009 potassium phosphates Nutrition 0.000 description 1
238000012545 processing Methods 0.000 description 1
229940090181 propyl acetate Drugs 0.000 description 1
235000018102 proteins Nutrition 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
230000017854 proteolysis Effects 0.000 description 1
150000003242 quaternary ammonium salts Chemical class 0.000 description 1
238000001953 recrystallisation Methods 0.000 description 1
239000011347 resin Substances 0.000 description 1
229920005989 resin Polymers 0.000 description 1
230000007017 scission Effects 0.000 description 1
230000021148 sequestering of metal ion Effects 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
239000004317 sodium nitrate Substances 0.000 description 1
235000010344 sodium nitrate Nutrition 0.000 description 1
239000007787 solid Substances 0.000 description 1
238000000638 solvent extraction Methods 0.000 description 1
235000012424 soybean oil Nutrition 0.000 description 1
239000003549 soybean oil Substances 0.000 description 1
241000894007 species Species 0.000 description 1
230000003068 static effect Effects 0.000 description 1
230000004936 stimulating effect Effects 0.000 description 1
239000010902 straw Substances 0.000 description 1
229910052712 strontium Inorganic materials 0.000 description 1
CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 description 1
239000011975 tartaric acid Substances 0.000 description 1
235000002906 tartaric acid Nutrition 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
238000012549 training Methods 0.000 description 1
NQPDZGIKBAWPEJ-UHFFFAOYSA-N valeric acid Chemical compound CCCCC(O)=O NQPDZGIKBAWPEJ-UHFFFAOYSA-N 0.000 description 1
239000012138 yeast extract Substances 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P29/00—Preparation of compounds containing a naphthacene ring system, e.g. tetracycline

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

BE533269D 1953-11-12 BE533269A (xx)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US1236502XA	1953-11-12	1953-11-12

Publications (1)

Publication Number	Publication Date
BE533269A true BE533269A (xx)

Family

ID=22409981

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE533269D BE533269A (xx)	1953-11-12

Country Status (1)

Country	Link
BE (1)	BE533269A (xx)

0
- BE BE533269D patent/BE533269A/fr unknown

Publication	Publication Date	Title
CH304875A (fr)	1955-01-31	Procédé de préparation d'une nouvelle substance antibiotique.
BE530983A (xx)
BE533886A (xx)
BE487301A (xx)
FR2489819A1 (fr)	1982-03-12	Antibiotique bmg162-af2 ayant notamment une activite antitumorale et son procede de preparation a partir d'une souche du genre bacillus
BE533269A (xx)
US3352759A (en)	1967-11-14	Process for producing cis-succinic acid of gauche form
BE536232A (xx)
FR2476128A1 (fr)	1981-08-21	Procede microbiologique de production de narasine et cultures contenant le microorganisme producteur streptomyces lydicus deboer et al-
BE544035A (xx)
FR2499855A1 (fr)	1982-08-20	Nouvelles substances a action carcinostatique et immuno-stimulante, procede pour les preparer a partir de bacteries du genre fusobacterium, et agent carcinostatique contenant de telles substances
BE538487A (xx)
BE600777A (xx)
CH398885A (fr)	1966-03-15	Procédé de préparation d'un antibiotique
BE641209A (xx)
BE556196A (xx)
BE600096A (xx)
BE555769A (xx)
BE530635A (xx)
CH333722A (fr)	1958-10-31	Procédé de préparation d'un nouvel antibiotique
BE511759A (xx)
CH347301A (fr)	1960-06-30	Procédé de préparation d'un nouvel antibiotique
BE510219A (xx)
BE572450A (xx)
BE528324A (xx)