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BE1017943A4 - Psoriasis treatment scalp. - Google Patents

Psoriasis treatment scalp. Download PDF

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Publication number
BE1017943A4
BE1017943A4 BE2007/0001A BE200700001A BE1017943A4 BE 1017943 A4 BE1017943 A4 BE 1017943A4 BE 2007/0001 A BE2007/0001 A BE 2007/0001A BE 200700001 A BE200700001 A BE 200700001A BE 1017943 A4 BE1017943 A4 BE 1017943A4
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BE
Belgium
Prior art keywords
oil
ylang
scalp
psoriasis
argan
Prior art date
Application number
BE2007/0001A
Other languages
French (fr)
Original Assignee
Erbisim Tahir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Priority to BE2007/0001A priority Critical patent/BE1017943A4/en
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Publication of BE1017943A4 publication Critical patent/BE1017943A4/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)

Abstract

Treatment against psoriasis and scalp problem, using a combination of vegetable oil, and essential oil, shampoo based on neutral, argan oil, avocado oil, jojoba oil, wheat germ oil, borage oil, baobab oil, ylang-ylang oil and rose geranium oil, is claimed. ACTIVITY : Antipsoriatic. MECHANISM OF ACTION : None given.

Description

       

  Description 

  
Traitement contre le psoriasis du cuir chevelu 

  
L'invention a pour but de lutter contre le psoriasis du cuir chevelu qui touche 2% à 3 % de la population Belge. A cette fin, un traitement d'un shampooing dermo-cosmétiques. Très souvent, le psoriasis du cuir chevelu provoque des squames épaisses et des plaques érythérriateuses. 

  
Différents traitements locaux ont déjà été proposés, vis-à-vis du psoriasis du cuir chevelu, mais sont difficiles à appliquer en raison du l'existence ou de la présence des cheveux. Notamment diverses préparations topiques sont disponibles, et comportent pour la plupart d'entre elles de l'acide salicylique associé à différents agents réducteurs, comme du goudron de houille, de l'anthraline, et/ou comportent différents dermocorticoïdes. 

  
Il existe plusieurs options thérapeutiques disponibles pour soigner le psoriasis: les traitements locaux (pommade, gel, crème) très contraignants, les photothérapies qui augmentent le risque de cancer de la peau, et les traitements systémiques qui présentent beaucoup d'effets secondaires et sont toxiques à long terme. Malheureusement, ces inconvénients ont amené 17% des patients à ne plus consulter de médecin pour soigner leur psoriasis. Un espoir se profile toutefois à l'horizon avec les agents biologiques qui ont été conçus pour apporter une alternative thérapeutique aux patients qui ne répondent plus aux traitements existants.

   Tous ces produits sont d'un usage délicat, car de nombreux effets secondaires peuvent apparaître, au rang desquels on peut noter une atrophie cutanée, des vergetures, un retard de cicatrisation des plaies, différents phénomènes de dessiccation cutanée, des folliculites, des éruptions acnéiformes, voire une dépigmentation du cuir chevelu. Le psoriasis est une dermatose fréquente, à évolution chronique caractérisée par des taches rouges plus ou moins étendues, bien circonscrites, recouvertes de squames sèches, abondantes et friables. Les lésions correspondantes siègent surtout aux coudes, aux genoux, au cuir chevelu, mais peuvent aussi envahir tout le corps. Traitement contre le psoriasis du cuir chevelu l'élément clé dans la composition du shampooing, qui réagit pour lutter contre le problème du cuir chevelu c'est l'huile d'argan.

   L'huile d'argan contient un stérol le schotténol qui conférerait à cette huile son action réparatrice et régénératrice au niveau de la peau aussi riche en tocophérols (Vitamine E) avec 80 % d'acide gras insaturé. 

  
Tocophérols (la vitamine E) 

  
C'est Propriétés : Le rôle physiologique de la vitamine est le principal antioxydant de l'organisme et joue un rôle dans nombreux phénomènes biologique impliquant les membranes cellulaires. Les bénéfices de cette protection anti- radicalaire ont été étudiés et démontrés dans de nombreux domaines thérapeutique : athérosclérose, ophtalmologie neurologie, hématologie.  Des études épidémiologiques ont montré que la vitamine E exerce un rôle protecteur vis-à-vis de certains cancers et maladies cardio-vasculaires. 

  
Il existe deux voies d'absorption de la vitamine au niveau cutané : 1[deg.] passe à travers la couche cornée, l'épiderme et la jonction dermo-épidermique. 2[deg.] Passe par le canal philo-sébacé et l'intérieur des follicules pileux. 

  
La vitamine E est directement absorbée dans le cortex des cheveux. Elle possède une grande affinité pour les petits vaisseaux sanguins. 

  
A aussi comme protection vis-à-vis des UV. La vitamine E possède un rôle protecteur vis-à-vis de tous les agents extérieurs générateurs de radicaux libres. On sait que le rayonnement solaire entraîne la production de radicaux libre oxygénés, en partie responsable des dommages cellulaires et génétique et induit une immunosuppression. 

  
De plus la vitamine E possède un rôle protecteur sur certain nombre d'enzyme de détoxifîcation qui permet de neutraliser le radical super oxyde. Les tissus conjonctifs dermiques constituent également une cible privilégiée des attaques radicalaires d'UV. La vitamine E aide a maintient de la structure de derme en limitant la formation des ponts entre les molécules de collagène et en inhibant Phyperplasie des fibres élastique 

  
Propriétés anti-inflammatoires, la vitamine E en piégeant les radicaux libres, inhibe le mécanisme de peroxydation qui, à partir de l'acide arachilidonique aboutit à la formation de prostaglandines, médiateurs physiologique de l'inflammation. 

  
Les acides gras insaturé ; Acide oléique 43 % Acide linoléique 37 % et en C 18-1 et C 18-2, acide palmitique 12 à 13% en C 16 et Acide stéarique 6% en C 18 d'autre part, la quasi absence d'acide linolénique fait que cette huile est peu susceptible de s'oxyder pendent la conservation, l'huile argan grâce à ses propriétés antioxydant permet de lutter contre le vieillissement. 

  
Deux compositions de traitement capillaire, les substances suivant : 

  
Formule 1 

  
On par d'un shampooing de base neutre, auquel nous allons ajouter l'huile végétale d'argan. Ce shampooing aura pour but d'agir contre le psoriasis du cuir chevelu. 

  
Aqua (eau), Ammonium lauryl sulfate (tensioactif ayant une action détergente et moussante),Coco-glucoside (issu de l'huile de Coco et du glucose : légèrement moussant, particulièrement bien supporté par la peau, lisse les cheveux et en facilite le démêlage),Glycerin (glycérine issue d'huiles végétales : protège la peau et les cheveux de la déshydratation) Caprylyl/capryl glucoside (tensioactif de sucre, émulsifiant),Coco betaine (détergent doux issu de la coco),Hydrolyzed wheat protein (protéines de blé hydrolysées),Sodium chloride (sel),Citric acid (régulateur de pH), l'huile d'argan. Pour le psoriasis  Formule 2 amélioré 

  
D'un shampooing de base neutre en ajoutant un mélange des huiles végétales et des huiles essentielles. Les huiles essentielles ont pour but d'éliminer l'odeur forte des huiles végétales et de parfumer le mélange pour qu'il ait une odeur agréable. 

  
Ce shampooing a pour but d'agir contre le psoriasis et d'éliminer les pellicules et dégraisser les cheveux, de supprimer les démangeaisons, la perte de cheveux et de donner une brillance et de la souplesse aux cheveux. 

  
Shampooing de base neutre auquel on ajoute les huiles suivant : l'huile d'argan, Huile d'Avocat, huile de jojoba, huile de germe de blé huile de bourrache, huile de baobab et en ajoutant les Huiles essentielles d'ylang-ylang et du géranium rosat.



  Description

  
Treatment against scalp psoriasis

  
The invention aims to fight against scalp psoriasis which affects 2% to 3% of the Belgian population. To this end, a treatment of a dermo-cosmetic shampoo. Very often, psoriasis of the scalp causes thick scales and erythema patches.

  
Various local treatments have already been proposed for scalp psoriasis, but are difficult to apply because of the existence or presence of the hair. In particular, various topical preparations are available, and most of them contain salicylic acid associated with various reducing agents, such as coal tar, anthralin, and / or comprise different topical corticosteroids.

  
There are several therapeutic options available to treat psoriasis: local treatments (ointment, gel, cream) very restrictive, phototherapies that increase the risk of skin cancer, and systemic treatments that have many side effects and are toxic long-term. Unfortunately, these inconveniences led 17% of patients to stop consulting a doctor to treat their psoriasis. There is hope, however, on the horizon with the biological agents that have been designed to provide a therapeutic alternative to patients who no longer respond to existing treatments.

   All these products are of a delicate use, because numerous side effects can appear, among which one can note a cutaneous atrophy, stretch marks, a delay of cicatrization of the wounds, various phenomena of cutaneous dessiccation, folliculitis, acneiform eruptions or even depigmentation of the scalp. Psoriasis is a frequent dermatosis, with chronic evolution characterized by red spots more or less extensive, well circumscribed, covered with dry, abundant and friable scales. The corresponding lesions sit mostly on the elbows, knees, scalp, but can also invade the whole body. Treatment against scalp psoriasis The key element in the composition of the shampoo, which reacts to fight against the problem of the scalp is argan oil.

   Argan oil contains a sterol schotténol that would give this oil its restorative and regenerative action on the skin as rich in tocopherols (Vitamin E) with 80% unsaturated fatty acid.

  
Tocopherols (vitamin E)

  
It is Properties: The physiological role of the vitamin is the main antioxidant of the body and plays a role in many biological phenomena involving cell membranes. The benefits of this radical protection have been studied and demonstrated in many therapeutic areas: atherosclerosis, ophthalmology neurology, hematology. Epidemiological studies have shown that vitamin E has a protective role against certain cancers and cardiovascular diseases.

  
There are two routes of vitamin absorption at the cutaneous level: 1 [deg.] Passes through the stratum corneum, the epidermis and the dermal-epidermal junction. 2 [deg.] Go through the philo-sebaceous canal and inside the hair follicles.

  
Vitamin E is directly absorbed into the hair's cortex. It has a great affinity for small blood vessels.

  
Also as protection against UV. Vitamin E has a protective role vis-à-vis all external agents generating free radicals. It is known that solar radiation causes the production of oxygen free radicals, partly responsible for cellular and genetic damage and induces immunosuppression.

  
In addition, vitamin E has a protective role on a number of detoxification enzyme that can neutralize the superoxide radical. Dermal connective tissue is also a preferred target for free radical UV attacks. Vitamin E helps maintain the dermis structure by limiting the formation of bridges between collagen molecules and inhibiting elastic fiber hyperplasia.

  
Anti-inflammatory properties, vitamin E by scavenging free radicals, inhibits the mechanism of peroxidation which, from arachilidonic acid results in the formation of prostaglandins, physiological mediators of inflammation.

  
Unsaturated fatty acids; Oleic acid 43% linoleic acid 37% and C 18-1 and C 18-2, palmitic acid 12 to 13% C 16 and stearic acid 6% C 18, the absence of linolenic acid that this oil is unlikely to oxidize during storage, argan oil thanks to its antioxidant properties helps fight against aging.

  
Two hair treatment compositions, the following substances:

  
Formula 1

  
We use a neutral base shampoo, to which we will add the vegetable oil of argan. This shampoo will aim to act against psoriasis of the scalp.

  
Aqua (water), Ammonium lauryl sulfate (surfactant with a detergent and foaming action), Coco-glucoside (derived from coconut oil and glucose: slightly foaming, particularly well supported by the skin, smoothes hair and facilitates detangling), Glycerin (glycerin from vegetable oils: protects skin and hair from dehydration) Caprylyl / capryl glucoside (sugar surfactant, emulsifier), Coco betaine (mild detergent from coconut), Hydrolyzed wheat protein (protein hydrolyzed wheat), sodium chloride (salt), citric acid (pH regulator), argan oil. For improved psoriasis Formula 2

  
From a neutral base shampoo by adding a blend of vegetable oils and essential oils. The essential oils are meant to eliminate the strong smell of vegetable oils and to perfume the mixture so that it has a pleasant smell.

  
This shampoo aims to act against psoriasis and eliminate dandruff and degrease hair, remove itching, hair loss and give a shine and flexibility to the hair.

  
Neutral base shampoo with the following oils: argan oil, avocado oil, jojoba oil, wheat germ oil borage oil, baobab oil and adding the essential oils of ylang-ylang and geranium rosat.


    

Claims (1)

Revendication Claim Un traitement sera mis en place contre le psoriasis et les problèmes du cuir chevelu par une combinaison d'huiles végétale et de l'huiles essentiel et d'un shampooing de base neutre, l'huile d'argan, Huile d'Avocat, huile de jojoba, huile de germe de blé huile de bourrache, huile de baobab, huile d'ylang-ylang et huile de géranium rosat. A treatment will be set up against psoriasis and scalp problems by a combination of vegetable oils and essential oils and a neutral base shampoo, argan oil, avocado oil, oil jojoba, wheat germ oil borage oil, baobab oil, ylang-ylang oil and rose geranium oil.
BE2007/0001A 2007-01-05 2007-01-05 Psoriasis treatment scalp. BE1017943A4 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BE2007/0001A BE1017943A4 (en) 2007-01-05 2007-01-05 Psoriasis treatment scalp.

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BE2007/0001A BE1017943A4 (en) 2007-01-05 2007-01-05 Psoriasis treatment scalp.

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BE1017943A4 true BE1017943A4 (en) 2010-01-12

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITBA20110029A1 (en) * 2011-06-04 2012-12-05 Ruggero Defente HERBAL AND VEGETABLE MIXTURE TO HELP THE GROWTH OF THE HAIR AND PREVENT THE FALL

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001066079A1 (en) * 2000-03-08 2001-09-13 Bodnar Tibor Cosmetic and dermatological composition for psoriatic skin, scalp treatment and care
WO2003077811A1 (en) * 2002-03-14 2003-09-25 Mcclung Jackie H Pharmaceutically active compounds containing phosphorous defficient oil
GB2411833A (en) * 2004-03-08 2005-09-14 Skin Salveation Ltd Composition for use in the treatment of dry skin conditions

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001066079A1 (en) * 2000-03-08 2001-09-13 Bodnar Tibor Cosmetic and dermatological composition for psoriatic skin, scalp treatment and care
WO2003077811A1 (en) * 2002-03-14 2003-09-25 Mcclung Jackie H Pharmaceutically active compounds containing phosphorous defficient oil
GB2411833A (en) * 2004-03-08 2005-09-14 Skin Salveation Ltd Composition for use in the treatment of dry skin conditions

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "Argan oil shampoo", INTERNET, pages 1 - 3, XP002534837, Retrieved from the Internet <URL:http://www.alibaba.com/product-tp/101067009/Argan_Oil_Shampoo.html> *
ANONYMOUS: "DermOrganic sulfate-free conditioning shampoo with argan oil, 12 fl. oz.", INTERNET, pages 1 - 3, XP002534836, Retrieved from the Internet <URL:http://www.aveyou.com/dermorganicsulfate-freeconditioningshampoowitharganoil12floz.aspx> *
ANONYMOUS: "Huile d'argan", INTERNET, pages 1 - 4, XP002534835, Retrieved from the Internet <URL:http://fr.wikipedia.org/wiki/Huile_d'argan> *
ANONYMOUS: "Natural argan oil shampoo 200 ml", INTERNET, pages 1 - 2, XP002534838, Retrieved from the Internet <URL:http://www.alibaba.com/product-free/103486010/Natural_Argan_Oil_Shampoo_200ml.html> *
CHARROUF Z ET AL: "Ethnoeconomical, Ethomedical, and Phytochemical Study of Argania Spinosa (L.) Skeels: A Review", JOURNAL OF ETHNOPHARMACOLOGY, ELSEVIER SCIENTIFIC PUBLISHERS LTD, IE, vol. 67, no. 1, 1 October 1992 (1992-10-01), pages 7 - 14, XP002242296, ISSN: 0378-8741 *
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; 1986, FERRANDO J: "[Clinical trial of a topical preparation containing urea, sunflower oil, evening primrose oil, wheat germ oil and sodium pyruvate, in several hyperkeratotic skin conditions]", XP002534839, Database accession no. NLM3528709 *
MAURIN R: "L'HUILE D'ARGAN ARGANIA SPINOSA (L.) SKEELS SAPOTACEAE. MISE AU POINT", O.C.L. OLEAGINEUX CORPS GRAS LIPIDES, EDITIONS JOHN LIBBEY EUROTEXT, MONTROUGE, FR, vol. 39, no. 5/06, 1 May 1992 (1992-05-01), pages 139 - 146, XP002037529, ISSN: 1258-8210 *
MEDICINA CUTÁNEA IBERO-LATINO-AMERICANA 1986, vol. 14, no. 2, 1986, pages 133 - 137, ISSN: 0210-5187 *
STUECKER M ET AL: "VITAMIN B12 CREAM CONTAINING AVOCADO OIL IN THE THERAPY OF PLAQUE PSORIASIS", DERMATOLOGY,, vol. 203, no. 2, 1 January 2001 (2001-01-01), pages 141 - 147, XP009003410, ISSN: 1018-8665 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITBA20110029A1 (en) * 2011-06-04 2012-12-05 Ruggero Defente HERBAL AND VEGETABLE MIXTURE TO HELP THE GROWTH OF THE HAIR AND PREVENT THE FALL

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