[go: up one dir, main page]

AU9094991A - Triplex-forming oligomers containing modified bases - Google Patents

Triplex-forming oligomers containing modified bases

Info

Publication number
AU9094991A
AU9094991A AU90949/91A AU9094991A AU9094991A AU 9094991 A AU9094991 A AU 9094991A AU 90949/91 A AU90949/91 A AU 90949/91A AU 9094991 A AU9094991 A AU 9094991A AU 9094991 A AU9094991 A AU 9094991A
Authority
AU
Australia
Prior art keywords
triplex
modified bases
containing modified
oligomers containing
forming oligomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU90949/91A
Inventor
Brian Froehler
Steven Krawczyk
Mark D. Matteucci
John Milligan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gilead Sciences Inc
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of AU9094991A publication Critical patent/AU9094991A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6839Triple helix formation or other higher order conformations in hybridisation assays
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU90949/91A 1990-11-23 1991-11-25 Triplex-forming oligomers containing modified bases Abandoned AU9094991A (en)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US61790790A 1990-11-23 1990-11-23
US617907 1990-11-23
US64338291A 1991-01-18 1991-01-18
US68342091A 1991-04-08 1991-04-08
US683420 1991-04-08
US68654691A 1991-04-17 1991-04-17
US68654791A 1991-04-17 1991-04-17
US68654491A 1991-04-17 1991-04-17
US686547 1991-04-17
US686544 1991-04-17
US686546 1991-04-17
US76673391A 1991-09-27 1991-09-27
US766733 1996-12-13
US643382 2000-08-21

Publications (1)

Publication Number Publication Date
AU9094991A true AU9094991A (en) 1992-06-25

Family

ID=27569857

Family Applications (1)

Application Number Title Priority Date Filing Date
AU90949/91A Abandoned AU9094991A (en) 1990-11-23 1991-11-25 Triplex-forming oligomers containing modified bases

Country Status (3)

Country Link
EP (1) EP0558634A4 (en)
AU (1) AU9094991A (en)
WO (1) WO1992009705A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6235887B1 (en) 1991-11-26 2001-05-22 Isis Pharmaceuticals, Inc. Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines
EP0637965B1 (en) * 1991-11-26 2002-10-16 Isis Pharmaceuticals, Inc. Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines
TW393513B (en) * 1991-11-26 2000-06-11 Isis Pharmaceuticals Inc Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines
AU3250093A (en) 1991-12-12 1993-07-19 Gilead Sciences, Inc. Nuclease stable and binding competent oligomers and methods for their use
US7038026B2 (en) 2000-05-26 2006-05-02 Centelion Purification of a triple heli formation with an immobilized oligonucleotide
FR2728264B1 (en) 1994-12-16 1997-01-31 Rhone Poulenc Rorer Sa DNA PURIFICATION BY TRIPLE PROPELLER FORMATION WITH A IMMOBILIZED OLIGONUCLEOTIDE
AU701106B2 (en) 1995-06-07 1999-01-21 Promega Biosciences, Inc. Novel carbamate-based cationic lipids
US6426407B1 (en) * 1995-06-07 2002-07-30 Codon Pharm. Residues for binding third strands to complementary nucleic acid duplexes of any base pair sequence
AU2696897A (en) * 1996-04-26 1997-11-19 Novartis Ag Modified oligonucleotides
US6093816A (en) 1996-06-27 2000-07-25 Isis Pharmaceuticals, Inc. Cationic lipids
US6034135A (en) * 1997-03-06 2000-03-07 Promega Biosciences, Inc. Dimeric cationic lipids
US5877220A (en) * 1997-03-06 1999-03-02 Genta, Incorporated Amide-based oligomeric cationic lipids
CN101671335A (en) 2001-05-31 2010-03-17 梅达莱克斯公司 Cytotoxins, prodrugs, linkers and stabilizers useful therefor
JP4806680B2 (en) 2004-05-19 2011-11-02 メダレックス インコーポレイテッド Self-sacrificing linker and drug conjugate
AU2006294554B2 (en) 2005-09-26 2013-03-21 E. R. Squibb & Sons, L.L.C. Antibody-drug conjugates and methods of use
CN118286245A (en) 2014-12-26 2024-07-05 埃莫里大学 N4-hydroxycytidine and derivatives and antiviral uses related thereto
HUE069306T2 (en) 2017-12-07 2025-02-28 Univ Emory N4-hydroxycytidine derivative and anti-viral uses related thereto
CN112778388B (en) * 2021-01-21 2022-08-23 大连医科大学 Nucleoside analogue and preparation method and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2006008C (en) * 1988-12-20 2000-02-15 Donald J. Kessler Method for making synthetic oligonucleotides which bind specifically to target sites on duplex dna molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use
AU7998491A (en) * 1990-05-25 1991-12-31 Gilead Sciences, Inc. Sequence-specific nonphotoactivated crosslinking agents which bind to the major groove of duplex dna
AU668886B2 (en) * 1991-08-30 1996-05-23 Johns Hopkins University, The Formation of triple helix complexes of double stranded DNA using nucleoside oligomers which comprise purine base analogs

Also Published As

Publication number Publication date
WO1992009705A1 (en) 1992-06-11
EP0558634A1 (en) 1993-09-08
EP0558634A4 (en) 1995-06-28

Similar Documents

Publication Publication Date Title
AU639126B2 (en) Oxorapamycin
AU7414291A (en) Data element switch
AU7286696A (en) Antisense oligomers
AU1142692A (en) Flowsplitting conveyor
AU9094991A (en) Triplex-forming oligomers containing modified bases
EP0456512A3 (en) Polyimidesiloxane oligomer
AU1719792A (en) Can ends
EP0516958A3 (en) Caffeoyl-coa-3-o-methyltransferase gene
AU9030991A (en) Improved capacitor-sensor
AU7804691A (en) N-pyridinesulfonyl-N-pyrimidinyl-or-triazinylureas
AU641667B2 (en) Conveyor system with cantilever carriers
GB8929182D0 (en) Stabilisation
GB9117682D0 (en) Objectoriented data bases
AU2831692A (en) Novel expression system
AU7726391A (en) Slitterscorer
AU2010992A (en) Novel azabicyclobenzisoquinolines
AU7566691A (en) Compostor
AU632357B2 (en) Label
AU8237891A (en) Conveyor
GB8818150D0 (en) Gene modification
AU7296291A (en) Carrier
GB8924143D0 (en) Novel oligomers
EP0498992A3 (en) Serum-free culture medium containing lysozyme
AU8090691A (en) Article carrying system
AU5711090A (en) Trailer-barrow