AU9094991A - Triplex-forming oligomers containing modified bases - Google Patents
Triplex-forming oligomers containing modified basesInfo
- Publication number
- AU9094991A AU9094991A AU90949/91A AU9094991A AU9094991A AU 9094991 A AU9094991 A AU 9094991A AU 90949/91 A AU90949/91 A AU 90949/91A AU 9094991 A AU9094991 A AU 9094991A AU 9094991 A AU9094991 A AU 9094991A
- Authority
- AU
- Australia
- Prior art keywords
- triplex
- modified bases
- containing modified
- oligomers containing
- forming oligomers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US61790790A | 1990-11-23 | 1990-11-23 | |
US617907 | 1990-11-23 | ||
US64338291A | 1991-01-18 | 1991-01-18 | |
US68342091A | 1991-04-08 | 1991-04-08 | |
US683420 | 1991-04-08 | ||
US68654691A | 1991-04-17 | 1991-04-17 | |
US68654791A | 1991-04-17 | 1991-04-17 | |
US68654491A | 1991-04-17 | 1991-04-17 | |
US686547 | 1991-04-17 | ||
US686544 | 1991-04-17 | ||
US686546 | 1991-04-17 | ||
US76673391A | 1991-09-27 | 1991-09-27 | |
US766733 | 1996-12-13 | ||
US643382 | 2000-08-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU9094991A true AU9094991A (en) | 1992-06-25 |
Family
ID=27569857
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU90949/91A Abandoned AU9094991A (en) | 1990-11-23 | 1991-11-25 | Triplex-forming oligomers containing modified bases |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP0558634A4 (en) |
AU (1) | AU9094991A (en) |
WO (1) | WO1992009705A1 (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6235887B1 (en) | 1991-11-26 | 2001-05-22 | Isis Pharmaceuticals, Inc. | Enhanced triple-helix and double-helix formation directed by oligonucleotides containing modified pyrimidines |
EP0637965B1 (en) * | 1991-11-26 | 2002-10-16 | Isis Pharmaceuticals, Inc. | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines |
TW393513B (en) * | 1991-11-26 | 2000-06-11 | Isis Pharmaceuticals Inc | Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines |
AU3250093A (en) | 1991-12-12 | 1993-07-19 | Gilead Sciences, Inc. | Nuclease stable and binding competent oligomers and methods for their use |
US7038026B2 (en) | 2000-05-26 | 2006-05-02 | Centelion | Purification of a triple heli formation with an immobilized oligonucleotide |
FR2728264B1 (en) | 1994-12-16 | 1997-01-31 | Rhone Poulenc Rorer Sa | DNA PURIFICATION BY TRIPLE PROPELLER FORMATION WITH A IMMOBILIZED OLIGONUCLEOTIDE |
AU701106B2 (en) | 1995-06-07 | 1999-01-21 | Promega Biosciences, Inc. | Novel carbamate-based cationic lipids |
US6426407B1 (en) * | 1995-06-07 | 2002-07-30 | Codon Pharm. | Residues for binding third strands to complementary nucleic acid duplexes of any base pair sequence |
AU2696897A (en) * | 1996-04-26 | 1997-11-19 | Novartis Ag | Modified oligonucleotides |
US6093816A (en) | 1996-06-27 | 2000-07-25 | Isis Pharmaceuticals, Inc. | Cationic lipids |
US6034135A (en) * | 1997-03-06 | 2000-03-07 | Promega Biosciences, Inc. | Dimeric cationic lipids |
US5877220A (en) * | 1997-03-06 | 1999-03-02 | Genta, Incorporated | Amide-based oligomeric cationic lipids |
CN101671335A (en) | 2001-05-31 | 2010-03-17 | 梅达莱克斯公司 | Cytotoxins, prodrugs, linkers and stabilizers useful therefor |
JP4806680B2 (en) | 2004-05-19 | 2011-11-02 | メダレックス インコーポレイテッド | Self-sacrificing linker and drug conjugate |
AU2006294554B2 (en) | 2005-09-26 | 2013-03-21 | E. R. Squibb & Sons, L.L.C. | Antibody-drug conjugates and methods of use |
CN118286245A (en) | 2014-12-26 | 2024-07-05 | 埃莫里大学 | N4-hydroxycytidine and derivatives and antiviral uses related thereto |
HUE069306T2 (en) | 2017-12-07 | 2025-02-28 | Univ Emory | N4-hydroxycytidine derivative and anti-viral uses related thereto |
CN112778388B (en) * | 2021-01-21 | 2022-08-23 | 大连医科大学 | Nucleoside analogue and preparation method and application thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2006008C (en) * | 1988-12-20 | 2000-02-15 | Donald J. Kessler | Method for making synthetic oligonucleotides which bind specifically to target sites on duplex dna molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use |
AU7998491A (en) * | 1990-05-25 | 1991-12-31 | Gilead Sciences, Inc. | Sequence-specific nonphotoactivated crosslinking agents which bind to the major groove of duplex dna |
AU668886B2 (en) * | 1991-08-30 | 1996-05-23 | Johns Hopkins University, The | Formation of triple helix complexes of double stranded DNA using nucleoside oligomers which comprise purine base analogs |
-
1991
- 1991-11-25 AU AU90949/91A patent/AU9094991A/en not_active Abandoned
- 1991-11-25 WO PCT/US1991/008811 patent/WO1992009705A1/en not_active Application Discontinuation
- 1991-11-25 EP EP92901107A patent/EP0558634A4/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO1992009705A1 (en) | 1992-06-11 |
EP0558634A1 (en) | 1993-09-08 |
EP0558634A4 (en) | 1995-06-28 |
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