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AU8769291A - Deoxyhypusyl hydroxylase inhibitors - Google Patents

Deoxyhypusyl hydroxylase inhibitors

Info

Publication number
AU8769291A
AU8769291A AU87692/91A AU8769291A AU8769291A AU 8769291 A AU8769291 A AU 8769291A AU 87692/91 A AU87692/91 A AU 87692/91A AU 8769291 A AU8769291 A AU 8769291A AU 8769291 A AU8769291 A AU 8769291A
Authority
AU
Australia
Prior art keywords
hydroxylase inhibitors
deoxyhypusyl hydroxylase
deoxyhypusyl
inhibitors
hydroxylase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU87692/91A
Inventor
Hartmut M Hanauske-Abel
Marc E Lalande
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston Childrens Hospital
Original Assignee
Boston Childrens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Childrens Hospital filed Critical Boston Childrens Hospital
Publication of AU8769291A publication Critical patent/AU8769291A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU87692/91A 1990-09-17 1991-09-17 Deoxyhypusyl hydroxylase inhibitors Abandoned AU8769291A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58383990A 1990-09-17 1990-09-17
US583839 1990-09-17

Publications (1)

Publication Number Publication Date
AU8769291A true AU8769291A (en) 1992-04-15

Family

ID=24334805

Family Applications (1)

Application Number Title Priority Date Filing Date
AU87692/91A Abandoned AU8769291A (en) 1990-09-17 1991-09-17 Deoxyhypusyl hydroxylase inhibitors

Country Status (2)

Country Link
AU (1) AU8769291A (en)
WO (1) WO1992005190A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789426A (en) * 1995-01-20 1998-08-04 Cornell Research Foundation, Inc. Method for the treatment of fibroproliferative disorders by application of inhibitors of protein hydroxylation
US5849587A (en) * 1995-06-09 1998-12-15 Cornell Research Foundation, Inc. Method of inhibiting viral replication in eukaryotic cells and of inducing apoptosis of virally-infected cells
US5846984A (en) * 1996-01-19 1998-12-08 The Trustees Of Columbia University In The City Of New York Use of ciclopirox or a pharmaceutically acceptable salt thereof for inhibiting neuronal cell damage or neuronal cell death
WO2003018014A2 (en) * 2001-08-23 2003-03-06 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Methods of inhibiting formation of vascular channels and profileration using pyridinone derivatives
GB2389581A (en) * 2002-06-12 2003-12-17 Viaxxel Biotech Gmbh Hydrogenated pyrimidines and their use as inhibitors of deoxyhypusine-synthase or hypusination of eIF-5A
US20120095058A1 (en) * 2003-12-03 2012-04-19 Hanauske-Abel H M Method of preventing survival of retrovirally cells and of inhibiting formation of infectious retroviruses
CN104926722A (en) * 2010-06-01 2015-09-23 拜欧赛里克斯公司 Hydroxypyridone derivatives, pharmaceutical compositions thereof, and their therapeutic use for treating proliferative diseases
WO2011153199A1 (en) * 2010-06-01 2011-12-08 Biotheryx, Inc. Methods of treating hematologic malignancies using 6-cyclohexyl-1-hydroxy-4-methyl-2(1h)-pyridone

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3687458T2 (en) * 1985-11-04 1993-07-29 Owen Galderma Lab Inc FILM-FORMING MEDICINAL PRODUCTS FOR THE ADMINISTRATION OF MEDICINAL PRODUCTS ON NAILS
LU86944A1 (en) * 1987-07-17 1989-03-08 Oreal COMPOSITION BASED ON HYDROXYPYRIDONE DERIVATIVES FOR REDUCING HAIR LOSS
EP0313305A3 (en) * 1987-10-22 1990-02-07 The Procter & Gamble Company Photoprotection compositions comprising chelating agents
DE3830509A1 (en) * 1988-09-08 1990-03-22 Hoechst Ag MEDICINAL PRODUCTS WITH SYNERGISTIC ANTIMYCOTIC AND ANTIVIRAL EFFECTIVENESS

Also Published As

Publication number Publication date
WO1992005190A1 (en) 1992-04-02

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