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AU8107098A - Leukotriene b4 antagonists, in particular 3-carba-tetrahydronaphthalene-ltb4 antagonists - Google Patents

Leukotriene b4 antagonists, in particular 3-carba-tetrahydronaphthalene-ltb4 antagonists

Info

Publication number
AU8107098A
AU8107098A AU81070/98A AU8107098A AU8107098A AU 8107098 A AU8107098 A AU 8107098A AU 81070/98 A AU81070/98 A AU 81070/98A AU 8107098 A AU8107098 A AU 8107098A AU 8107098 A AU8107098 A AU 8107098A
Authority
AU
Australia
Prior art keywords
antagonists
carba
tetrahydronaphthalene
leukotriene
ltb4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU81070/98A
Inventor
Bernd Buchmann
Wolfgang Frohlich
Claudia Giesen
Hartwig Hennekes
Stefan Jaroch
Werner Skuballa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU8107098A publication Critical patent/AU8107098A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/54—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/38—Alcohols containing six-membered aromatic rings and other rings and having unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0058—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a not condensed ring different from a five-membered ring
    • C07C405/0066—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a not condensed ring different from a five-membered ring to a six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU81070/98A 1997-05-23 1998-05-22 Leukotriene b4 antagonists, in particular 3-carba-tetrahydronaphthalene-ltb4 antagonists Abandoned AU8107098A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1997122853 DE19722853A1 (en) 1997-05-23 1997-05-23 Leukotriene B¶4¶ antagonists, especially 3-carba-tetrahydronaphthalene LTB¶4¶ antagonists
DE19722853 1997-05-23
PCT/EP1998/003136 WO1998052912A2 (en) 1997-05-23 1998-05-22 Leukotriene b4 antagonists, in particular 3-carba-tetrahydronaphthalene-ltb4 antagonists

Publications (1)

Publication Number Publication Date
AU8107098A true AU8107098A (en) 1998-12-11

Family

ID=7831041

Family Applications (1)

Application Number Title Priority Date Filing Date
AU81070/98A Abandoned AU8107098A (en) 1997-05-23 1998-05-22 Leukotriene b4 antagonists, in particular 3-carba-tetrahydronaphthalene-ltb4 antagonists

Country Status (3)

Country Link
AU (1) AU8107098A (en)
DE (1) DE19722853A1 (en)
WO (1) WO1998052912A2 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3917597A1 (en) * 1989-05-26 1990-11-29 Schering Ag NEW LEUKOTRIA-B (DOWN ARROW) 4 (DOWN ARROW) DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS
US5344836A (en) * 1991-11-11 1994-09-06 Ono Pharmaceutical Co., Ltd. Fused benzeneoxyacetic acid derivatives
DE4236540A1 (en) * 1992-10-22 1994-06-23 Schering Ag New leukotriene B4 derivs.
DE4242390A1 (en) * 1992-12-09 1994-06-16 Schering Ag New cycloaliphatic leukotriene-B4 derivs. - used as leukotriene antagonists e.g. for treating inflammation, allergy, skin disease or leukaemia
US5399588A (en) * 1993-12-14 1995-03-21 American Home Products Corporation Naphthalenylmethyl cycloalkenone acetic acids and analogs thereof useful as aldose reductase inhibitors

Also Published As

Publication number Publication date
WO1998052912A3 (en) 1999-02-25
DE19722853A1 (en) 1998-12-10
WO1998052912A2 (en) 1998-11-26

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase