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AU7414300A - Method for the production of substituted pyrimidine derivatives - Google Patents

Method for the production of substituted pyrimidine derivatives

Info

Publication number
AU7414300A
AU7414300A AU74143/00A AU7414300A AU7414300A AU 7414300 A AU7414300 A AU 7414300A AU 74143/00 A AU74143/00 A AU 74143/00A AU 7414300 A AU7414300 A AU 7414300A AU 7414300 A AU7414300 A AU 7414300A
Authority
AU
Australia
Prior art keywords
production
pyrimidine derivatives
substituted pyrimidine
substituted
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU74143/00A
Inventor
Cristina Alonso-Alija
Jan Janichen
Michael Preiss
Alexander Straub
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU7414300A publication Critical patent/AU7414300A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/01Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/31Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU74143/00A 1999-09-08 2000-08-28 Method for the production of substituted pyrimidine derivatives Abandoned AU7414300A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19942809 1999-09-08
DE19942809A DE19942809A1 (en) 1999-09-08 1999-09-08 Process for the preparation of substituted pyrimidine derivatives
PCT/EP2000/008362 WO2001017998A2 (en) 1999-09-08 2000-08-28 Method for the production of substituted pyrimidine derivatives

Publications (1)

Publication Number Publication Date
AU7414300A true AU7414300A (en) 2001-04-10

Family

ID=7921171

Family Applications (1)

Application Number Title Priority Date Filing Date
AU74143/00A Abandoned AU7414300A (en) 1999-09-08 2000-08-28 Method for the production of substituted pyrimidine derivatives

Country Status (3)

Country Link
AU (1) AU7414300A (en)
DE (1) DE19942809A1 (en)
WO (1) WO2001017998A2 (en)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10122894A1 (en) * 2001-05-11 2002-11-14 Bayer Ag New pyrazolo(3,4-b)pyridin-3-yl)-5-pyrimidinyl sulfonates, are soluble guanyl cyclase stimulants useful e.g. for treating cardiovascular, thromboembolic or central nervous system diseases
DE102007028320A1 (en) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituted oxazolidinones and their use
DE102007028406A1 (en) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituted oxazolidinones and their use
DE102007028319A1 (en) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituted oxazolidinones and their use
DE102007028407A1 (en) 2007-06-20 2008-12-24 Bayer Healthcare Ag Substituted oxazolidinones and their use
EP2138178A1 (en) 2008-06-28 2009-12-30 Bayer Schering Pharma Aktiengesellschaft Oxazolidninones for the treatment fo chronic obstructive pulmonary disease (COPD) and/or asthma
US20130178475A1 (en) 2010-03-17 2013-07-11 Ironwood Pharmaceuticals, Inc. sGC STIMULATORS
CA2803292C (en) 2010-06-30 2016-06-14 Ironwood Pharmaceuticals, Inc. Sgc stimulators
JP5878546B2 (en) 2010-11-09 2016-03-08 アイアンウッド ファーマシューティカルズ インコーポレイテッド sGC stimulant
CA2861804C (en) 2011-12-27 2021-10-26 Ironwood Pharmaceuticals, Inc. 2-benzyl,3(pyrimidin-2-yl)substituted pyrazoles useful as sgc stimulators
KR102060376B1 (en) 2012-05-10 2019-12-30 바이엘 파마 악티엔게젤샤프트 Antibodies capable of binding to the coagulation factor xi and/or its activated form factor xia and uses thereof
WO2014047111A1 (en) 2012-09-18 2014-03-27 Ironwood Pharmaceuticals, Inc. Sgc stimulators
WO2014047325A1 (en) 2012-09-19 2014-03-27 Ironwood Pharmaceuticals, Inc. Sgc stimulators
EP3998260B1 (en) 2013-03-15 2023-11-01 Cyclerion Therapeutics, Inc. Sgc stimulators
EA032028B1 (en) 2013-12-11 2019-03-29 Айронвуд Фармасьютикалз, Инк. sGC STIMULATORS
EP3094327A1 (en) 2014-01-13 2016-11-23 Ironwood Pharmaceuticals, Inc. USE OF sGC STIMULATORS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS
EP3194382B1 (en) 2014-09-17 2021-09-08 Cyclerion Therapeutics, Inc. Pyrazole derivatives as sgc stimulators
WO2016044445A2 (en) 2014-09-17 2016-03-24 Ironwood Pharmaceuticals, Inc. sGC STIMULATORS
JP2017527604A (en) 2014-09-17 2017-09-21 アイアンウッド ファーマシューティカルズ インコーポレイテッド sGC stimulant
CN108463224A (en) 2015-12-14 2018-08-28 铁木医药有限公司 SGC stimulants are used for the application of gastrointestinal dysfunction treatment
CN109476686B (en) 2016-07-07 2022-01-18 赛克里翁治疗有限公司 Phosphorus prodrugs of sGC stimulators
CA3029333A1 (en) 2016-07-07 2018-01-11 Ironwood Pharmaceuticals, Inc. Solid forms of an sgc stimulator
SG11201901729YA (en) 2016-09-02 2019-03-28 Ironwood Pharmaceuticals Inc Fused bicyclic sgc stimulators
IL266372B2 (en) 2016-11-08 2023-11-01 Cyclerion Therapeutics Inc Sgc stimulators
TWI812601B (en) 2016-11-08 2023-08-21 美商賽克瑞恩醫療公司 TREATMENT OF CNS DISEASES WITH sGC STIMULATORS
US20190381039A1 (en) 2016-12-13 2019-12-19 Cyclerion Therapeutics, Inc. USE OF sGC STIMULATORS FOR THE TREATMENT OF ESOPHAGEAL MOTILITY DISORDERS
AU2018388629B2 (en) 2017-12-19 2023-11-16 Tisento Therapeutics Inc. sGC stimulators
MX2023004856A (en) 2018-03-07 2023-11-24 Cyclerion Therapeutics Inc Crystalline forms of an sgc stimulator.
AU2019301683A1 (en) 2018-07-11 2021-02-11 Tisento Therapeutics Inc. Use of sGC stimulators for the treatment of mitochonrial disorders
JP2022509815A (en) 2018-11-28 2022-01-24 トパデュール ファルマ アーゲー New dual-acting soluble guanylate cyclase activators and phosphodiesterase inhibitors and their uses
WO2021195403A1 (en) 2020-03-26 2021-09-30 Cyclerion Therapeutics, Inc. Deuterated sgc stimulators
US20230128032A1 (en) 2020-03-31 2023-04-27 Curtails Llc Early Drug Interventions to Reduce COVID-19 Related Respiratory Distress, Need for Respirator Assist and Death
AU2022261862A1 (en) 2021-04-20 2023-11-30 Tisento Therapeutics Inc. Sgc stimulators
WO2022225902A1 (en) 2021-04-20 2022-10-27 Cyclerion Therapeutics, Inc. Treatment of cns diseases with sgc stimulators
WO2024086179A1 (en) 2022-10-18 2024-04-25 Tisento Therapeutics, Inc. Pyrimidine sgc stimulators
WO2024086182A1 (en) 2022-10-18 2024-04-25 Tisento Therapeutics Inc. Treatment of mitochondrial diseases with sgc stimulators
CN118772140A (en) * 2023-04-07 2024-10-15 四川大学 A class of compounds and their use in treating hDHODH-mediated diseases

Also Published As

Publication number Publication date
WO2001017998A3 (en) 2001-10-11
DE19942809A1 (en) 2001-03-15
WO2001017998A2 (en) 2001-03-15

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase