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AU7262700A - Enhanced phage display library of human vh fragments and methods for producing same - Google Patents

Enhanced phage display library of human vh fragments and methods for producing same

Info

Publication number
AU7262700A
AU7262700A AU72627/00A AU7262700A AU7262700A AU 7262700 A AU7262700 A AU 7262700A AU 72627/00 A AU72627/00 A AU 72627/00A AU 7262700 A AU7262700 A AU 7262700A AU 7262700 A AU7262700 A AU 7262700A
Authority
AU
Australia
Prior art keywords
fragments
human
methods
phage display
display library
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU72627/00A
Inventor
Michael Dan
Joycelyn Entwistle
Howard Kaplan
Saran Narang
Jamshid Tanha
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Viventia Bio Inc
Original Assignee
Novopharm Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA 2282179 external-priority patent/CA2282179A1/en
Application filed by Novopharm Biotech Inc filed Critical Novopharm Biotech Inc
Publication of AU7262700A publication Critical patent/AU7262700A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU72627/00A 1999-09-07 2000-09-07 Enhanced phage display library of human vh fragments and methods for producing same Abandoned AU7262700A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CA 2282179 CA2282179A1 (en) 1999-09-07 1999-09-07 Enhanced phage display library
CA2282179 1999-09-07
US16354699P 1999-11-04 1999-11-04
US60163546 1999-11-04
PCT/CA2000/001027 WO2001018058A2 (en) 1999-09-07 2000-09-07 Enhanced phage display library of human vh fragments and methods for producing same

Publications (1)

Publication Number Publication Date
AU7262700A true AU7262700A (en) 2001-04-10

Family

ID=25681199

Family Applications (1)

Application Number Title Priority Date Filing Date
AU72627/00A Abandoned AU7262700A (en) 1999-09-07 2000-09-07 Enhanced phage display library of human vh fragments and methods for producing same

Country Status (3)

Country Link
EP (1) EP1214352A2 (en)
AU (1) AU7262700A (en)
WO (1) WO2001018058A2 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001297872B2 (en) 2000-11-17 2006-11-09 University Of Rochester In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
ES2376454T3 (en) 2000-12-22 2012-03-14 Grad, Carole, Legal Representative Of Howard, Kaplan EXPRESSION BOOKS IN FAGO OF VH HUMAN FRAGMENTS.
WO2003054021A2 (en) * 2001-12-20 2003-07-03 Agricultural Research Council Semi-synthetic antibody fragment combinatorial library based on avian immunoglobulin genes
AU2004239065B2 (en) * 2003-05-14 2008-05-15 Domantis Limited A process for recovering polypeptides that unfold reversibly from a polypeptide repertoire
WO2006081473A2 (en) 2005-01-28 2006-08-03 Children's Medical Center Corporation Methods for diagnosis and prognosis of epithelial cancers
AU2007217861A1 (en) 2006-02-17 2007-08-30 Children's Medical Center Corporation Free NGAL as a biomarker for cancer
US7888044B2 (en) 2006-04-10 2011-02-15 Trustees Of Boston University Melanoma biomarker and methods of uses
CA3056116A1 (en) 2007-06-22 2008-12-31 Randolph Watnick Methods and uses thereof of prosaposin
AU2009335000B2 (en) 2008-12-30 2014-11-13 Children's Medical Center Corporation Method of predicting acute appendicitis
US9081008B2 (en) 2009-12-04 2015-07-14 James Sherley Detecting and counting tissue—specific stem cells and uses thereof
AU2010339794B2 (en) 2009-12-17 2016-09-22 Children's Medical Center Corporation Saposin-A derived peptides and uses thereof
ES2974506T3 (en) 2011-12-22 2024-06-27 Childrens Medical Center Peptides derived from saposin-A and uses thereof
CN103215255B (en) * 2012-01-19 2015-06-17 深圳华大基因科技有限公司 Primer set for amplifying immunoglobulin light chain CDR3 sequence and application thereof
US10078085B2 (en) 2012-08-22 2018-09-18 Mogam Biothechnology Institute Screening and engineering method of super-stable immunoglobulin variable domains and their uses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639863A (en) * 1994-06-21 1997-06-17 Dan; Michael D. Human monoclonal antibodies specific to cell cycle independent glioma surface antigen
IL127127A0 (en) * 1998-11-18 1999-09-22 Peptor Ltd Small functional units of antibody heavy chain variable regions

Also Published As

Publication number Publication date
EP1214352A2 (en) 2002-06-19
WO2001018058A3 (en) 2001-10-04
WO2001018058A2 (en) 2001-03-15

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase